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Selective attention and emotional vulnerability: Assessing the causal basis of their association through the experimental manipulation of attentional bias.
Abstract
Although it is well-established that vulnerability to negative emotion is associated with attentional bias toward aversive information, the causal basis of this association remains undetermined. Two studies addressed this issue by experimentally inducing differential attentional responses to emotional stimuli using a modified dot probe task, and then examining the impact of such attentional manipulation on subsequent emotional vulnerability. The results supported the hypothesis that the induction of attentional bias should serve to modify emotional vulnerability, as revealed by participants' emotional reactions to a final standardized stress task. These findings provide a sound empirical basis for the previously speculative proposal that attentional bias can causally mediate emotional vulnerability, and they suggest the possibility that cognitive-experimental procedures designed to modify selective information processing may have potential therapeutic value.
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“An initial study found that subliminal ABM training did not induce attentional changes to threatening stimuli (MacLeod, Rutherford, Campbell, Ebsworthy, 2002).”
From Advancing the treatment of anxiety disorders in transition‐age youth: a review of the therapeutic effects of unconscious exposure. (2025) · cites this paper as MacLeod, Rutherford, Campbell, Ebsworthy, 2002
In the citing paper
“Also, training attentional bias towards negative stimuli increases self-reported distress to a laboratory stressor (MacLeod, Rutherford, Campbell, Ebsworthy, & Holker, 2002)”
From Attentional bias and emotional reactivity as predictors and moderators of behavioral treatment for social phobia (2013) · cites this paper as MacLeod, Rutherford, Campbell, Ebsworthy, & Holker, 2002
In the citing paper
“Selective biases in attention can be modified by a simple computerized technique; the Attention Bias Modification task (ABM), pioneered by Colin MacLeod et al. [19]”
In the citing paper
“These simple, computer-based training tasks have been found to alter processing biases (eg, in attention) in both non-clinical (Browning et al, 2010b; MacLeod et al, 2002) and clinical groups (Amir et al, 2009)”
From Using an Experimental Medicine Model to Explore Combination Effects of Pharmacological and Cognitive Interventions for Depression and Anxiety (2011) · cites this paper as MacLeod et al, 2002
In the citing paper
“In line with previous work, both citalopram (Harmer et al, 2004; Murphy et al, 2009) and positive cognitive bias training (Browning et al, 2010b; MacLeod et al, 2002) on their own produced relatively positive changes in emotional bias, consistent with the idea that this may be a common process in treatments of emotional disorders (Harmer, 2008).”
From Using an Experimental Medicine Model to Explore Combination Effects of Pharmacological and Cognitive Interventions for Depression and Anxiety (2011) · cites this paper as MacLeod et al, 2002
In the citing paper
“After promising preclinical studies (MacLeod et al., 2002), first successful clinical applications have been reported in targeted prevention (See et al., 2009) and in clinically anxious patient groups (Amir et al., 2009;Schmidt et al., 2009), and targeted prevention (See et al., 2009) with maintenance of clinical improvement reported four months after the training (Schmidt et al., 2009).”
From Addiction, adolescence, and the integration of control and motivation (2011) · cites this paper as MacLeod et al., 2002
In the citing paper
“inducing a negative attentional bias in healthy participants increases anxiety (4)”
From Lateral prefrontal cortex mediates the cognitive modification of attentional bias (2010) · cites this paper as [4]
In the citing paper
“Thus, not only is exposure ineffective for those who are negatively biased, training attention toward threat in non-avoidant populations has also been found to increase rather than decrease anxiety in both adults and children [41,43,44].”
From Can mindfulness be too much of a good thing? The value of a middle way (2019) · cites this paper as [43]
In the citing paper
“One such potential intervention is attention bias modification (ABM), a computer-delivered treatment for anxiety that emerged from research in experimental psychopathology (MacLeod & Mathews, 2012;MacLeod, Rutherford, Campbell, Ebsworthy, & Holker, 2002).”
From Anxiety and attention to threat: cognitive mechanisms and treatment with attention bias modification (2016) · cites this paper as MacLeod et al., 2002
In the citing paper
“These differing views point to a potential limitation of ABM-threat-avoidance training which focuses on modifying an automatic bias in initial orienting to threat (MacLeod et al., 2002), rather than other attention mechanisms such as top-down attention control which may support emotion regulation and resilience to anxiety (e.g., Derryberry & Rothbart, 1997).”
From Anxiety and attention to threat: cognitive mechanisms and treatment with attention bias modification (2016) · cites this paper as MacLeod et al., 2002
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“…normally distributed (positive skew and kurtosis) and therefore the median instead of the mean reaction time was used for calculating bias index (MacLeod et al., 2002).1 Bias index was calculated by subtracting the median response time for trials inwhich the probe appeared on the location of…”
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“However, from another point of view, people who are highly anxious are more likely to have their attention drawn to threatening objects and information and fi nd it more diffi cult to disengage their attention from such stimuli (e.g. Keogh and French, 2001; MacLeod et al., 2002).”
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“Around this time, two other CBM studies also appeared (e.g. Grey and Mathews 2000; MacLeod et al. 2002).”
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“By presenting these probes distally from the target stimulus, it is hoped that participants will come to attend away from this category of information [35].”
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“The dot-probe task was used to measure attentional bias toward negative stimuli (MacLeod et al., 2002) of individuals with SubD or NC.”
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“This might be due to the limited number of training trials in our study compared to other studies using attentional retraining procedures (e.g., MacLeod et al., 2002).”
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“In addition, studies with non-clinical highanxious participants show that ABM training typically reduces stress vulnerability in the face of lab-induced (Amir et al., 2008; Bar-Haim et al., 2011) or real-life (See et al., 2009) stressors.”
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“Further, attention to threat can be altered via training protocols that implicitly modify attention patterns [27,28].”
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“For example, using an attentional modification training (AMT; [69]) paradigm, Najmi & Amir [70] attempted to reduce attentional bias to threat and approach behaviors to feared objects in subclinical OCD participants.”
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“Recently, many researchers have begun to develop re-trainings of biased cognitive processes such as attention([53]) or interpretation,([54]) in an attempt to identify the causal role of these processes as well as to augment existing therapies.”
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“consists of the presentation of a number of probe response trials which encourage the deployment of attention away from threat (MacLeod et al., 2002) or towards positive stimuli (Grafton, Ang, & Macleod, 2012).”
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“This is a particularly pertinent point given the rapid development of attention bias modification (ABM) techniques designed to alter the habitual deployment of attention to threat-related information in high trait anxiety (MacLeod, Rutherford, Campbell, Ebsworthy, & Holker, 2002).”
Attention Bias to Emotional Faces in Young Children Exposed to Intimate Partner Violence
Swartz, J. R., Graham‐Bermann, S. A., Mogg, K., Bradley, B. P., & Monk, C. S. (2011) · Journal of Child & Adolescent Trauma · doi:10.1080/19361521.2011.573525 · Cited by 28
“And, as discussed previously, research on healthy individuals suggests that altering attention biases through attention training can lead to changes in levels of anxiety (Eldar et al., 2008; MacLeod et al., 2002).”
BackgroundLancee, J., Yasiney, S. L., Brendel, R. S., Boffo, M., Clarke, P., & Salemink, E. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174531 · Cited by 27
Hang, Y., Xu, L., Wang, C., Zhang, G., & Zhang, N. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113892 · Cited by 29
Cognitive processes predict worry and anxiety under different stressful situations
Feng, Y.-C., Krahé, C., Koster, E. H. W., Lau, J. Y. F., & Hirsch, C. R. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104168 · Cited by 33
Botelho, C., Pasion, R., Prata, C., & Barbosa, F. (2022) · Biological Psychology · doi:10.1016/j.biopsycho.2022.108475 · Cited by 29
Approach-Bias Retraining and Other Training Interventions as Add-On in the Treatment of AUD Patients
Wiers, R. W. H. J., Pan, T., Dessel, P. V., Rinck, M., & Lindenmeyer, J. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_421 · Cited by 31
Abend, R., Pine, D. S., Fox, N. A., & Bar‐Haim, Y. (2014) · Clinical Psychological Science · doi:10.1177/2167702614526571 · Cited by 33
Notebaert, L., Grafton, B., Clarke, P., Rudaizky, D., Chen, N. T. M., & MacLeod, C. (2018) · JMIR Serious Games · doi:10.2196/10993 · Cited by 30
“Moreover, studies that have manipulated patterns of attentional bias (using attentional bias modification [ABM] procedures) have shown that attentional bias causally contributes to anxiety vulnerability, as a change in attentional bias produces a consequent change in anxiety vulnerability [3,4-6].”
BackgroundMethodSelf-citationNicotine decreases attentional bias to negative-affect-related Stroop words among smokers
Rzetelny, A., Gilbert, D. G., Hammersley, J. J., Radtke, R. C., Rabinovich, N. E., & Small, S. L. (2008) · Nicotine & Tobacco Research · doi:10.1080/14622200802097514 · Cited by 27
Van Bockstaele, B., Salemink, E., Bögels, S. M., & Wiers, R. W. (2017) · Cognition and Emotion · doi:10.1080/02699931.2015.1092418 · Cited by 26
Rumination Moderates the Effects of Cognitive Bias Modification of Attention
Hall, K. A. A., & Joormann, J. (2013) · Cognitive Therapy and Research · doi:10.1007/s10608-013-9581-9 · Cited by 26
“For example, most studies have assessed change in attention biases using the dot-probe task (e.g., Amir et al. 2008; Baert et al. 2010; MacLeod et al. 2002; Wells and Beevers 2010).”
BackgroundMethodHerrington, J. D., Maddox, B. B., McVey, A. J., Franklin, M. E., Yerys, B. E., Miller, J. S., & Schultz, R. T. (2017) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.03.009 · Cited by 26
Lechner, W. V., Sidhu, N. K., Kittaneh, A. A., & Anand, A. (2019) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2019.01.017 · Cited by 38
Depression and affective flexibility: A valence-specific bias
Wen, A., & Yoon, K. L. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103502 · Cited by 29
Clinical efficacy of cognitive bias modification interventions
Blackwell, S. E. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30170-x · Cited by 26
The Reliability and Validity of Response-Based Measures of Attention Bias
Meissel, E. E. E., Liu, H., Stevens, E. S., Evans, T. C., Britton, J. C., Letkiewicz, A. M., & Shankman, S. A. (2021) · Cognitive Therapy and Research · doi:10.1007/s10608-021-10212-w · Cited by 26
Working Memory, Test Anxiety and Effective Interventions: A Review
Mowbray, T. (2012) · The Australian Educational and Developmental Psychologist · doi:10.1017/edp.2012.16 · Cited by 26
Nishiguchi, Y., Takano, K., & Tanno, Y. (2015) · Emotion · doi:10.1037/a0039117 · Cited by 29
Hudlická, E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801851-4.00016-1 · Cited by 27
The causal role of selective attention for thin-ideal images on negative affect and rumination
Dondzilo, L., Rieger, E., Palermo, R., & Bell, J. (2018) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2018.07.006 · Cited by 26
Metadata
- Authors
- MacLeod, C., Rutherford, E., Campbell, L., Ebsworthy, G., & Holker, L.
- Affiliations
- The University of Western Australia (AU)
- ORCID
- MacLeod, Colin
- Venue
- Journal of Abnormal Psychology
- Published
- 2002-02
- Volume
- 111
- Issue
- 1
- Pages
- 107-123
- ISSN
- 0021-843X (ISSN-L)
- 1939-1846
- OpenAlex
- W2122758649
- Cited by
- 1,334
- References
- 48
- Citations by year
- 2026: 13 · 2025: 31 · 2024: 41 · 2023: 35 · 2022: 44 · 2021: 80 · 2020: 54 · 2019: 73 · 2018: 65 · 2017: 61 · 2016: 80 · 2015: 96 · 2014: 84 · 2013: 96 · 2012: 83
- FWCI
- 32.64
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Abnormal Psychology (publishedVersion)
- PubMed (publishedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attentional bias, emotional vulnerability, selective attention, negative emotions, dot-probe task, stress reactivity, causal mediation analysis, cognitive bias modification
- MeSH terms
- Adolescent, Psychology, Adolescent, Adult, Affect, Attention, Female, Humans, Male
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