Cited by 84Attention Deficit Hyperactivity DisorderChild and Adolescent Psychosocial and Emotional DevelopmentDevelopmental and Educational Neuropsychology

Early development of comorbidity between symptoms of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD)

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Harvey, Elizabeth A., Breaux, Rosanna P., Lugo-Candelas, Claudia I.·2016·Journal of Abnormal Psychology

Abstract

Attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are among the most common childhood disorders and frequently co-occur. The present study sought to advance our understanding of how comorbidity between ADHD and ODD develops during the preschool years by testing a cross-lagged model that integrates 2 prominent models: the developmental precursor model and the correlated risk factors model. Participants were 199 children (107 boys) who took part in a longitudinal study of preschoolers with behavior problems. Parent reports of ADHD and ODD symptoms were collected annually from ages 3 to 6 and a family history interview was administered at age 3. In support of the developmental precursors model, ADHD symptoms predicted later argumentative/defiant symptoms. In support of the correlated risk factors model, family histories of ADHD and ODD/CD symptoms were correlated risk factors that uniquely predicted ADHD and anger/irritable symptoms in children. Results suggest that the correlated risk factors model may best explain the development of comorbidity between symptoms of ADHD and anger/irritability, whereas the developmental precursors model may better explain the development of comorbidity between symptoms of ADHD and argumentative/defiance.

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Crossref · 10.1037/abn0000090

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  • Early onset of comorbidity between ADHD and ODD or CD represents a risk factor for the appearance of late ADHD symptoms, such as anger and irritability in young people.

    “the early onset of a comorbidity between ADHD and ODD or CD represents a risk factor for the appearance of late ADHD symptoms, such as anger and irritability in young people”

    From ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors (2018) · cites this paper as Harvey et al., 2016

    The Discussion (Correlated Risk Factors Model; page unavailable) identifies family histories of ADHD and ODD/CD—not early comorbidity itself—as correlated risk factors that independently predict ADHD and anger/irritability, respectively. The paper also classifies anger/irritability as an ODD symptom, not a late ADHD symptom, and reports that ADHD symptoms predicted later argumentative/defiant symptoms. (LLM, conf=0.88)

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  • Symptoms originating from ADHD disrupt family functioning and consequently contribute to the development of ODD symptoms.

    “the symptoms originating from ADHD disrupt family functioning and, consequently, contribute to the development of ODD symptoms”

    From ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors (2018) · cites this paper as Harvey et al., 2016

    The ‘Theoretical Models of Comorbidity Between ADHD and ODD’ section describes the proposed pathway: ADHD symptoms may disrupt family functioning and thereby place children at risk for ODD. But it presents this as a theory, not an established causal finding. The ‘Developmental Precursors Model’ discussion says the causal mechanisms still need to be identified. (LLM, conf=0.88)

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  • When ADHD, CD, and ODD emerge in adolescence, the reviewed literature attributes greater responsibility to environmental factors.

    “when the disorders emerge in adolescence, the reviewed literature attributes greater responsibility to environmental factors”

    From ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors (2018) · cites this paper as Harvey et al., 2016

    The Discussion’s “Correlated Risk Factors Model” section suggests that ODD expressed in later childhood or adolescence may be more influenced by environmental causes. It presents this as a possibility, not an established finding, and does not make the same age-specific claim about ADHD or CD. Page numbers are not available in the supplied passages. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Early expression of ODD may be more influenced by genetic factors, whereas later expression in childhood or adolescence may be more influenced by environmental causes.

    “the early expression of ODD may be more in fl uenced by genetic factors, whereas later expression of ODD in childhood or adolescence may be more in fl uenced by environmental causes”

    From ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors (2018) · cites this paper as Harvey, Breaux, & Lugo-Candelas, 2016

  • ADHD symptoms may affect the family environment in a way that predisposes towards the development of behavioral manifestations of ODD.

    “ADHD symptoms may a ff ect the family environment in the sense that, in turn, they predispose towards the development of behavioral manifestations of ODD”

    From ADHD, CD, and ODD: Systematic review of genetic and environmental risk factors (2018) · cites this paper as Harvey et al., 2016

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Cites

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7 of the 71 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. American Psychiatric Association 2013 Diagnostic and statistical manual of mental disorders, 5th Edition: DSM-5 5th Arlington, VA American Psychiatric Association
  2. Barkley RA 2006 Attention-deficit hyperactivity disorder: A handbook for diagnosis and treatment 3rd New York, NY Guilford Press

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Authors
Harvey, E. A., Breaux, R. P., & Lugo-Candelas, C. I.
Affiliations
University of Massachusetts Amherst (US)
Venue
Journal of Abnormal Psychology
Published
2016-02
Volume
125
Issue
2
Pages
154-167
ISSN
  • 0021-843X (ISSN-L)
  • 1939-1846
OpenAlex
W2263717711
Cited by
84
References
71
Citations by year
2026: 5 · 2025: 6 · 2024: 5 · 2023: 9 · 2022: 10 · 2021: 7 · 2020: 5 · 2019: 9 · 2018: 9 · 2017: 17 · 2016: 1
FWCI
10.66
Type
journal article
Language
en
Open access
Locations
  • Journal of Abnormal Psychology (publishedVersion, other-oa)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (MH60132)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
Keywords
attention deficit hyperactivity disorder, oppositional defiant disorder, comorbidities, preschool children, family history (medicine), anger and irritability, child behavior problems, cross-lagged panel model
MeSH terms
Attention Deficit Disorder with Hyperactivity, Child, Child Development, Child, Preschool, Female, Humans, Longitudinal Studies, Male, Psychological Tests, Risk Factors, Comorbidity, Attention Deficit and Disruptive Behavior Disorders

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