Leveraging human-centered design to implement modern psychological science: Return on an early investment.
Open accessAbstract
Although classic models of implementation emphasized the importance of innovation characteristics in their adoption and sustained use, contemporary implementation research and practice have deprioritized these variables. Human-centered design (HCD) is an approach that grounds product development in information collected about the people and settings that will ultimately use those products. HCD has strong roots in psychological theory, but its application is typically limited to the development of digital technologies. HCD is rarely applied to the design of psychosocial innovations-including both service-recipient-facing interventions and implementation strategies-within the applied psychological disciplines. The current article reviews the psychological origins of HCD and details pathways through which HCD theories and methods can be leveraged to advance the "core tasks" of contemporary implementation research and practice in psychology. These include (a) identification of multilevel implementation determinants through specification of user needs and contexts; (b) tailoring of implementation strategies, such as contextually driven intervention redesign; and (c) evaluating implementation mechanisms and outcomes, including disentangling how the core HCD focus on usability relates to closely associated implementation variables such as acceptability, feasibility, and appropriateness. Collectively, these applications provide directions through which to leverage the mature field of HCD, maximize psychology's return on its early theoretical investment, and promote the large-scale impact of findings from across the applied fields of psychology. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
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The project's approach was grounded in HCD, an iterative approach to problem solving in which stakeholders are involved in all steps.
“The project’s approach was grounded in HCD, an iterative approach to problem solving in which stakeholders are involved in all steps, from problem identification through prototype testing and evaluation (7, 8).”
From Cocreating the ICU-PAUSE Tool for Intensive Care Unit–Ward Transitions (2022) · cites this paper as [7]
The authors used human-centered design methods across multiple internal medicine residency programs to create and iteratively prototype a structured ICU-to-ward transfer tool embedded within the EHR.
“Accordingly, we used human-centered design methods across multiple internal medicine residency programs to create and iteratively prototype a structured ICU-to-ward transfer tool embedded within the electronic health record (EHR) [11].”
From Improving Communication in Intensive Care Unit to Ward Transitions: Protocol for Multisite National Implementation of the ICU-PAUSE Handoff Tool (2023) · cites this paper as [11]
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AI-Assisted Causal Pathway Diagram for Human-Centered Design
Zhong, R., Shin, D.-H., Meza, R. D., Klasnja, P., Colusso, L. F., & Hsieh, G. (2024) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3613904.3642179 · Cited by 24 · see citing works
Woerner, M., Sams, N., Nales, C. J. R., Gorstein, T., Johnson, M., Mosser, B. A., & Areán, P. A. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.840169 · Cited by 24 · see citing works
Self-citationMata-Greve, F., Johnson, M., Pullmann, M. D., Friedman, E. C., Fillipo, I. G., Comtois, K. A., & Areán, P. A. (2021) · JMIR Mental Health · doi:10.2196/28360 · Cited by 19 · see citing works
Self-citationAgapie, E., Haldar, S., & Poblete, S. G. (2022) · Proceedings of the ACM on Human-Computer Interaction · doi:10.1145/3555610 · Cited by 21 · see citing works
Kammer-Kerwick, M., Takasaki, K., Kellison, J. B., & Sternberg, J. (2022) · Applied Research in Quality of Life · doi:10.1007/s11482-022-10051-1 · Cited by 20 · see citing works
O’Hara, K. L., Knowles, L. M., Guastaferro, K., & Lyon, A. R. (2022) · Implementation Research and Practice · doi:10.1177/26334895221131052 · Cited by 22 · see citing works
Self-citationArtificial intelligence overdependence in tourism
Christou, P. (2024) · Current Issues in Tourism · doi:10.1080/13683500.2024.2369192 · Cited by 19 · see citing works
Redesigning the Hospital Environment to Improve Restfulness
Catley, C. D., Paynter, K., Jackson, K., Huggins, A., Ji, J., Sanka, S. A., Simkins, M., Maddox, T. M., & Lyons, P. G. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.47790 · Cited by 19 · see citing works
Wakschlag, L. S., Finlay‐jones, A. L., MacNeill, L. A., Kaat, A. J., Brown, C. H., Davis, M. M., Franklin, P. D., Berkel, C., Krogh‐Jespersen, S., & Smith, J. D. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.827412 · Cited by 18 · see citing works
Leveraging Implementation Science in Human-Centred Design for Digital Health
Waddell, A., Seguin, J. P., Wu, L., Stragalinos, P., Wherton, J. P., Watterson, J., Prawira, C. O., Olivier, P. L., Manning, V., Lubman, D. I., et al. (2024) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3613904.3642161 · Cited by 22 · see citing works
Cocreating the ICU-PAUSE Tool for Intensive Care Unit–Ward Transitions
Santhosh, L., Rojas, J. C., Garcia, B., Thomashow, M., & Lyons, P. G. (2022) · ATS Scholar · doi:10.34197/ats-scholar.2021-0135in · Cited by 21 · see citing works
“The project ’ s approach was grounded in HCD, an iterative approach to problem solving in which stakeholders are involved in all steps, from problem identification through prototype testing and evaluation (7, 8).”
Hallgren, K. A., Cohn, E. B., Ries, R. K., & Atkins, D. C. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.840409 · Cited by 17 · see citing works
Jenness, J. L., Bhattacharya, A., Kientz, J. A., Munson, S. A., & Nagar, R. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104065 · Cited by 14 · see citing works
Kepper, M. M., L’Hotta, A. J., Shato, T., Kwan, B. M., Glasgow, R. E., Luke, D. A., Graham, A. K., Baumann, A. A., Brownson, R. C., & Morse, B. (2024) · Implementation Science · doi:10.1186/s13012-024-01410-7 · Cited by 16 · see citing works
Davis, K. S., Anderson, M., Yang, C., Choukas‐Bradley, S., Bell, B. T., & Slovák, P. (2024) · Journal of Adolescent Research · doi:10.1177/07435584241291163 · Cited by 17 · see citing works
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Advancing youth co-design of ethical guidelines for AI-powered digital mental health tools
Figueroa, C. A., Ramos, G., Psihogios, A. M., Ekuban, E., Bansie, P., de Haas, M., Karnik, N. S., Ajilore, O., Anderson, E. E., & Stiles‐Shields, C. (2025) · Nature Mental Health · doi:10.1038/s44220-025-00467-7 · Cited by 12 · see citing works
Brewer, S. K., Corbin, C. M., Baumann, A. A., Stirman, S. W., Jones, J. M., Pullmann, M. D., Lyon, A. R., Panel, M. E., Aalsma, M. C., Aldridge, W. A., et al. (2024) · Implementation Science Communications · doi:10.1186/s43058-024-00592-x · Cited by 15 · see citing works
Self-citationEnhancing Exposure Treatment for Youths With Chronic Pain: Co-design and Qualitative Approach
Schemer, L., Hess, C. W., Orden, A. R. V., Birnie, K. A., Harrison, L. E., Glombiewski, J. A., & Simons, L. E. (2023) · Journal of Participatory Medicine · doi:10.2196/41292 · Cited by 13 · see citing works
Marcotte, L. M., Langevin, R., Hempstead, B. H., Ganguly, A., Lyon, A. R., Weiner, B. J., Akinsoto, N., Houston, P. L., Fang, V., & Hsieh, G. (2024) · Implementation Science Communications · doi:10.1186/s43058-024-00569-w · Cited by 11 · see citing works
Self-citationLenze, E. J., Torous, J. B., & Areán, P. A. (2023) · Neuropsychopharmacology · doi:10.1038/s41386-023-01664-7 · Cited by 10 · see citing works
Self-citationFukui, E. M., Lyons, P. G., Harris, E., McCune, E. K., Rojas, J. C., & Santhosh, L. (2023) · JMIR Research Protocols · doi:10.2196/40918 · Cited by 9 · see citing works
“Accordingly, we used human-centered design methods across multiple internal medicine residency programs to create and iteratively prototype a structured ICU-to-ward transfer tool embedded within the electronic health record (EHR) [11].”
Pendekatan Human Centered Design pada Perancangan User Experience Aplikasi Pemesanan Menu Cafe
Putra, F. P., & Tedyyana, A. (2021) · SISTEMASI · doi:10.32520/stmsi.v10i2.1229 · Cited by 9 · see citing works
Rosenbaum, S., Moberg, J., Chesire, F., Mugisha, M., Ssenyonga, R., Ochieng, M., Simbi, C. M. C., Nakyejwe, E., Ngatia, B., Gabriel Rada, G., et al. (2024) · F1000Research · doi:10.12688/f1000research.132580.3 · Cited by 8 · see citing works
The Connections Matter: Bi-Directional Learning in Program Evaluation and Practice-Oriented Research
Douglas, S. R., Page, A. C., Moltu, C., Kyron, M. J., & Satterthwaite, T. (2023) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-023-01304-8 · Cited by 11 · see citing works
Yakubu, T., Jhajj, P., Pawer, S., West, N., Amed, S., Tang, T. S., & Görges, M. (2024) · JMIR Diabetes · doi:10.2196/64267 · Cited by 8 · see citing works
Zhai, S., Yuwen, W., Zyniewicz, T. L., Sonney, J., Hash, J. B., Chen, M., & Ward, T. M. (2025) · Digital Health · doi:10.1177/20552076251348579 · Cited by 7 · see citing works
Larson, M. F., & Cook, C. R. (2023) · Issues in clinical child psychology · doi:10.1007/978-3-031-20006-9_28 · Cited by 8 · see citing works
Hankins, J. S., Potter, M. B., Fernandez, M. E., Melvin, C. L., DiMartino, L., Jacobs, S., Bosworth, H. B., King, A. A., Simon, J., Glassberg, J., et al. (2023) · Frontiers in Health Services · doi:10.3389/frhs.2022.1024541 · Cited by 8 · see citing works
Integrating Single-Session Interventions into Existing Care Systems
Cohen, K. A., Smith, A. C., & Schleider, J. L. (2024) · Advances in Psychiatry and Behavioral Health · doi:10.1016/j.ypsc.2024.04.006 · Cited by 8 · see citing works
Chu, W., Becker, K. D., Boustani, M. M., Park, A. L., & Chorpita, B. F. (2022) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2021.11.003 · Cited by 7 · see citing works
Landis‐Lewis, Z., Flynn, A. J., Janda, A. M., & Shah, N. J. (2022) · JMIR Research Protocols · doi:10.2196/34990 · Cited by 6 · see citing works
Holdheide, L. R., Osher, D. D., Cirks, V., & Chagnon, E. (2024) · Evaluation & the Health Professions · doi:10.1177/01632787241291052 · Cited by 7 · see citing works
3D Printing for Accessible Education: A Case Study in Assistive Technology Adoption
Holloway, L. M., Butler, M., Waddell, A., & Marriott, K. (2025) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3706598.3713689 · Cited by 8 · see citing works
Cornell, E. G., Harris, E., McCune, E., Fukui, E., Lyons, P. G., Rojas, J. C., & Santhosh, L. (2023) · Diagnosis · doi:10.1515/dx-2023-0046 · Cited by 6 · see citing works
shinyDLRs: A dashboard to facilitate derivation of diagnostic likelihood ratios.
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Edwards, G. F., Zagarese, V., Jesso, S. T., Jesso, M. N., Harden, S. M., & Parker, S. H. (2023) · Frontiers in Health Services · doi:10.3389/frhs.2022.981450 · Cited by 8 · see citing works
Pielech, M., Beckmann, E. A., & Dorsainvil, H. (2025) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2025.102038 · Cited by 5 · see citing works
Kornfield, R., Popowski, S. A., Tack, E. B., Svoboda, J., Herrera, M. A., Nguyen, T., Knapp, A. A., Mohr, D. C., & Meyerhoff, J. (2025) · JMIR Formative Research · doi:10.2196/68950 · Cited by 8 · see citing works
Kim, B., Guyer, M. E., & Keshavan, M. S. (2024) · Early Intervention in Psychiatry · doi:10.1111/eip.13496 · Cited by 5 · see citing works
Perceived barriers transitioning to adult healthcare among adults with spina bifida
Kritikos, T. K., Stiles‐Shields, C., Leard, R. S., & Holmbeck, G. N. (2024) · Health Care Transitions · doi:10.1016/j.hctj.2024.100054 · Cited by 5 · see citing works
Editorial Perspective: A systems approach to addressing young people's mental health
Hobbs, T., Berry, V., & Fonagy, P. (2024) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.14077 · Cited by 7 · see citing works
Last, B. S., Jans, L. K., & Schleider, J. L. (2023) · Behavior Therapy · doi:10.1016/j.beth.2024.06.004 · Cited by 4 · see citing works
Collaboration and co-creation: fostering student learning through syllabus redesign
Iverson, M., Reiter, J. E., & Martin, L. (2025) · Social Work Education · doi:10.1080/02615479.2025.2502397 · Cited by 4 · see citing works
Addressing Psychological Needs in Designing for a Sustainable Circular Economy
Wölfel, C., & Burmester, M. (2023) · Design science and innovation · doi:10.1007/978-981-99-7532-7_9 · Cited by 4 · see citing works
Triplett, N. S., Mbwayo, A., Kiche, S. W., Sackey, E., AlRasheed, R., Okoth, D. A., Nyaboke, O. A., Amanya, C., & Dorsey, S. (2024) · SSM - Mental Health · doi:10.1016/j.ssmmh.2024.100319 · Cited by 4 · see citing works
Najafi, M. K., Alizadeh, Z., Dehghani, M., Herzog, P., & Azimisefat, P. (2024) · Children and Youth Services Review · doi:10.1016/j.childyouth.2024.107663 · Cited by 7 · see citing works
Hameed, W., Katiyar, J., & Avan, B. I. (2024) · Mental Health & Prevention · doi:10.1016/j.mhp.2024.200356 · Cited by 6 · see citing works
Farooq, A., Abbey, A. B. N., & Onukwulu, E. C. (2024) · Gulf Journal of Advance Business Research · doi:10.51594/gjabr.v2i6.57 · Cited by 4 · see citing works
Well-Being Across the Globe - New Perspectives, Concepts, Correlates and Geography
Mullings, J., Paul, T., Dunn, L. L., Arbor, S., Meeks-Gardner, J., & Arbor, T. (2023) · Sustainable development · doi:10.5772/intechopen.104197 · Cited by 6 · see citing works
Frazier, M. C., Balis, L. E., Armbruster, S. D., Estabrooks, P. A., & Harden, S. M. (2023) · Translational Behavioral Medicine · doi:10.1093/tbm/ibad052 · Cited by 4 · see citing works
March, C. A., Naame, E., Libman, I. M., Proulx, C. N., Siminerio, L. M., Miller, E. P., & Lyon, A. R. (2025) · JMIR Diabetes · doi:10.2196/64096 · Cited by 3 · see citing works
Self-citationProfiling and Predicting Faculty Assessment Behavior in Surgical Education
Patel, R. K., Jenkins, P. D., Lee, E., Nitzkorski, J. R., Seshadri, R. M., Rhee, R., Cook, M. R., Shelton, J., Doberne, J., Jesneck, J. L., et al. (2025) · Journal of surgical education · doi:10.1016/j.jsurg.2025.103737 · Cited by 3 · see citing works
Maulana, I. R., Fitria, M., Faizah, C. N., Adharani, D. H., Jinan, S. N., & Dawood, R. (2024) · International HCI and UX Conference in Indonesia (CHIuXiD) · doi:10.1109/chiuxid64022.2024.10860581 · Cited by 3 · see citing works
Tirtanadi, K., Johnson, K. A., Epler, A. J., & Chen, J. A. (2025) · Patient Education and Counseling · doi:10.1016/j.pec.2025.108745 · Cited by 2 · see citing works
Human-Centered Design for Inclusive Peer Mentoring of Graduate Teaching Assistants
Anders, A. D., Walton, A., Muhammad, A. A., Cabada, C., Deam, N., Speltz, E. D., Everett, R., Guskaroska, A., Haffner, J., & Payton, C. (2023) · College English · doi:10.58680/ce202332760 · Cited by 3 · see citing works
Coetzer-Liversage, A., Stein, L. A. R., Stephens, M., Jefferis, E. S., Step, M. M., Crowe, A. R., & Sloboda, Z. (2024) · Health Behavior Research · doi:10.4148/2572-1836.1265 · Cited by 2 · see citing works
Waddell, A., Watterson, J., Basur, D., Prawira, C. O., Picco, L., Lam, T., Olivier, P. L., Seguin, J. P., Kay, L., & Nielsen, S. (2025) · Frontiers in Digital Health · doi:10.3389/fdgth.2025.1600836 · Cited by 2 · see citing works
Kindervaag, E., Hauge, Å. L., & Johnsen, S. Å. K. (2025) · HERD Health Environments Research & Design Journal · doi:10.1177/19375867251365849 · Cited by 3 · see citing works
Locke, J. J., Corbin, C. M., Cook, C. R., Ehrhart, M. G., Davis, C. J., & Lyon, A. R. (2023) · Global Implementation Research and Applications · doi:10.1007/s43477-023-00080-9 · Cited by 3 · see citing works
Self-citationScience for behavioral health systems change: evolving research-policy-public partnerships
Southam‐Gerow, M. A., Sale, R., Robinson, A., Sanborn, V., Wu, J., Boggs, B., Riso, A., Scalone, M., & Sandman, A. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1359143 · Cited by 2 · see citing works
Seff, I., Deitch, J., Harker, A., Rodríguez, C., Andia, T. S., Pena, T. A., & Stark, L. (2024) · PLoS ONE · doi:10.1371/journal.pone.0303588 · Cited by 3 · see citing works
Ethical and Social Consideration in Mechatronics
Mobarak, M. H., Hasan, M. J., Rahman, M., Rana, M., Shaikat, A. S., & Tasnim, R. (2024) · Emerging trends in mechatronics · doi:10.1007/978-981-97-7117-2_8 · Cited by 2 · see citing works
Comtois, K. A., Salisbury, J., Clifton, R. L., Grumet, J. G., & Adrian, M. C. (2025) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2025.2491061 · Cited by 2 · see citing works
Universitas Katolik Musi Charitas, I., Wibagso, S. S., Celesta, I., & Universitas Katolik Musi Charitas, I. (2021) · Matrix Jurnal Manajemen Teknologi dan Informatika · doi:10.31940/matrix.v11i3.150-161 · Cited by 2 · see citing works
Olusanya, O., Collier, W. G. A., Marshall, S., Knapp, V., & Baldwin, A. (2022) · Journal of Legal Research Methodology · doi:10.19164/jlrm.v2i1.1240 · Cited by 2 · see citing works
Ahuna, J. K., Becker, K. D., & Chorpita, B. F. (2023) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-023-01295-6 · Cited by 2 · see citing works
Lyon, A. R. (2024) · School Mental Health · doi:10.1007/s12310-024-09711-4 · Cited by 3 · see citing works
Self-citationAssessing the Usability of Complex Psychosocial Interventions: The Intervention Usability ScalePreprint
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Proceedings from the Fourth Annual Conference of the Norwegian Network for Implementation Research
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Bridging mental health research and practice: the role of human-centered design in fidelity
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User evaluation of an implementation toolkit for maternal–newborn care settings
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Kierkegaard, P., Su, B., Moghul, M. R., Cahill, D., & James, N. D. (2026) · Implementation Science Communications · doi:10.1186/s43058-026-01041-7 · Cited by 1 · see citing works
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Evaluation Review of Mobile Apps Supporting Adolescents’ and Young Adults’ Mental Health
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Factors Beyond Compensation Associated with Uptake of Voluntary Medical Male Circumcision in Zambia
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- Authors
- Lyon, A. R., Brewer, S. K., & Areán, P. A.
- Affiliations
- University of Washington (US)
- Venue
- American Psychologist
- Published
- 2020-11
- Volume
- 75
- Issue
- 8
- Pages
- 1067-1079
- ISSN
- 0003-066X (ISSN-L)
- 1935-990X
- PMC
- PMC7709137
- OpenAlex
- W3110183584
- Cited by
- 152
- References
- 84
- Citations by year
- 2026: 16 · 2025: 26 · 2024: 44 · 2023: 29 · 2022: 19 · 2021: 15 · 2020: 3
- FWCI
- 17.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- American Psychologist (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R34MH109605, P50MH115837)
- Topics
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Physical Sciences › Computer Science › Human-Computer Interaction › Usability and User Interface Design
- Physical Sciences › Computer Science › Human-Computer Interaction › Innovative Human-Technology Interaction
- Keywords
- human-centered design, implementation research, implementation strategies, psychosocial interventions, user needs, usability, implementation factors, implementation mechanisms, acceptability, feasibility, appropriateness, applied psychology
- MeSH terms
- Implementation Science, Humans, Psychology
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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