A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Inoki, K., Li, Y., Zhu, T., Wu, J., & Guan, K.-L. (2002) · Nature Cell Biology · doi:10.1038/ncb839 · Cited by 3,083

Role of insulin-like growth factors in embryonic and postnatal growth

Baker, J., Liu, J.-P., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80085-6 · Cited by 2,463

Satellite Cells and the Muscle Stem Cell Niche

Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

Pevny, L., Simon, M. C., Robertson, E., Klein, W. H., Tsai, S.-F., D'Agati, V., Orkin, S. H., & Costantini, F. (1991) · Nature · doi:10.1038/349257a0 · Cited by 1,308

Genomic imprinting in mammalian development: a parental tug-of-war

Moore, T. (1991) · Trends in Genetics · doi:10.1016/0168-9525(91)90230-n · Cited by 1,281

Genetic conflicts in human pregnancy

Haig, D. (1993) · The Quarterly Review of Biology · doi:10.1086/418300 · Cited by 1,253

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

Thomas, K. R., & Capecchi, M. R. (1990) · Nature · doi:10.1038/346847a0 · Cited by 896

Review: Sex and the human placenta: Mediating differential strategies of fetal growth and survival

Clifton, V. L. (2010) · Placenta · doi:10.1016/j.placenta.2009.11.010 · Cited by 868

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia

Rane, S. G., Dubus, P., Mettus, R. V., Galbreath, E. J., Boden, G., Reddy, E. P., & Barbacid, M. (1999) · Nature Genetics · doi:10.1038/8751 · Cited by 700

Parental transmission of type 2 diabetes: the Framingham Offspring Study

Meigs, J. B., Cupples, L. A., & Wilson, P. W. (2000) · Diabetes · doi:10.2337/diabetes.49.12.2201 · Cited by 666

Insulin-like growth factor signaling in fish

Wood, A. W., Duan, C., & Bern, H. A. (2005) · International Review of Cytology · doi:10.1016/s0074-7696(05)43004-1 · Cited by 657

Effects of an Igf1 Gene Null Mutation on Mouse Reproduction

Baker, J., Hardy, M. P., Zhou, J., Bondy, C., Lupu, F., Bellvé, A. R., & Efstratiadis, A. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.7.8813730 · Cited by 674

The role of the insulin-like growth factors in the central nervous system

D’Ercole, A. J., Ye, P., Calikoglu, A. S., & Gutierrez-Ospina, G. (1996) · Molecular Neurobiology · doi:10.1007/bf02740625 · Cited by 447

Evidence of Placental Translation Inhibition and Endoplasmic Reticulum Stress in the Etiology of Human Intrauterine Growth Restriction

Yung, H.-W., Calabrese, S., Hynx, D., Hemmings, B. A., Cetin, I., Charnock-Jones, D. S., & Burton, G. J. (2008) · The American Journal of Pathology · doi:10.2353/ajpath.2008.071193 · Cited by 388

Long-term effect of in vitro culture of mouse embryos with serum on mRNA expression of imprinting genes, development, and behavior

Fernández-Gonzalez, R., Moreira, P., Bilbao, A., Jiménez, A., Pérez-Crespo, M., Ramírez, M. A., De Fonseca, F. R., Pintado, B., & Gutiérrez-Adán, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308560101 · Cited by 370

Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormone

Episkopou, V, Maeda, S., Nishiguchi, S., Shimada, K., Gaitanaris, G. A., Gottesman, M. E., & Robertson, E. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.6.2375 · Cited by 325

Dwarfism and Impaired Gut Development in Insulin-Like Growth Factor II mRNA-Binding Protein 1-Deficient Mice

Hansen, T. V. O., Hammer, N. A., Nielsen, J., Madsen, M., Dalbaeck, C., Wewer, U. M., Christiansen, J., & Nielsen, F. C. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.10.4448-4464.2004 · Cited by 251

Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity

Nishizawa, M., Chonabayashi, K., Nomura, M., Tanaka, A., Nakamura, M., Inagaki, A., Nishikawa, M., Takei, I., Oishi, A., Tanabe, K., et al. (2016) · Cell stem cell · doi:10.1016/j.stem.2016.06.019 · Cited by 234

Strain difference in establishment of mouse embryonic stem (ES) cell lines

Kawase, E., Suemori, H., Takahashi, N., Okazaki, K., Hashimoto, K., & Nakatsuji, N. (1994) · The International Journal of Developmental Biology · doi:10.1387/ijdb.7981049 · Cited by 203

The Consequences of Altered Somatotropic System on Reproduction1

Chandrashekar, V., Zaczek, D., & Bartke, A. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.027060 · Cited by 175

Fetal Macrosomia: Etiologic Factors

LANGER, O. (2000) · Clinical Obstetrics and Gynecology · doi:10.1097/00003081-200006000-00006 · Cited by 171

First-trimester ADAM12 and PAPP-A as markers for intrauterine fetal growth restriction through their roles in the insulin-like growth factor system

Cowans, N. J., & Spencer, K. (2007) · Prenatal Diagnosis · doi:10.1002/pd.1665 · Cited by 160

Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland.

Mesiano, S., Mellon, S. H., & Jaffe, R. B. (1993) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.76.4.8473412 · Cited by 135

Growth factors and beta cell replication

Vasavada, R. C., Gonzalez-Pertusa, J. A., Fujinaka, Y., Fiaschi-Taesch, N., Cozar-Castellano, I., & Garcia-Ocaña, A. (2006) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.08.003 · Cited by 133

Network inference with Granger causality ensembles on single-cell transcriptomics

Deshpande, A., Chu, L.-F., Stewart, R., & Gitter, A. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110333 · Cited by 130

THE GROWTH WITHOUT GROWTH HORMONE SYNDROME

Geffner, M. E. (1996) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70345-5 · Cited by 108

PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma

Mohlin, S., Hamidian, A., von Stedingk, K., Bridges, E., Wigerup, C., Bexell, D., & Påhlman, S. (2015) · Cancer Research · doi:10.1158/0008-5472.can-15-0708 · Cited by 104

Maternally-inherited Grb10 reduces placental size and efficiency

Charalambous, M., Cowley, M., Geoghegan, F., Smith, F. M., Radford, E. J., Marlow, B. P., Graham, C. F., Hurst, L. D., & Ward, A. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.10.011 · Cited by 101

The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation

Melrose, J., Shu, C., Whitelock, J. M., & Lord, M. S. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.01.008 · Cited by 96

An upstream repressor element plays a role in Igf2 imprinting

Eden, S., Constancia, M., Hashimshony, T., Dean, W., Goldstein, B., Johnson, A. C., Keshet, I., Reik, W., & Cedar, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.13.3518 · Cited by 95

IGF2 in memory, neurodevelopmental disorders, and neurodegenerative diseases

Alberini, C. M. (2023) · Trends in Neurosciences · doi:10.1016/j.tins.2023.03.007 · Cited by 89

ATF3 drives senescence by reconstructing accessible chromatin profiles

Zhang, C., Zhang, X., Huang, L., Guan, Y., Huang, X., Tian, X., Zhang, L., & Tao, W. (2021) · Aging Cell · doi:10.1111/acel.13315 · Cited by 84

Genomic imprinting as an adaptative model of developmental plasticity

Radford, E. J., Ferrón, S. R., & Ferguson-Smith, A. C. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.063 · Cited by 64

Insulin-like growth factors and skeletal growth: possibilities for therapeutic interventions

Van Wyk, J. J., & Smith, E. P. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.12.6201 · Cited by 53