Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease

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Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

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ApoE Promotes the Proteolytic Degradation of Aβ

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ApoE genotype accounts for the vast majority of AD risk and AD pathology

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Aβ Secretion and Plaque Formation Depend on Autophagy

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Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity*

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The Plasmin System Is Induced by and Degrades Amyloid-β Aggregates

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Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels <i>in vivo</i>

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Alzheimer's Disease β-Amyloid Peptide Is Increased in Mice Deficient in Endothelin-converting Enzyme*

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Brain Renin–Angiotensin System as Novel and Potential Therapeutic Target for Alzheimer’s Disease

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Neuroprotective Effects of Ginsenoside Rf on Amyloid-β-Induced Neurotoxicity in vitro and in vivo

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Redox-Active Metal Ions and Amyloid-Degrading Enzymes in Alzheimer’s Disease

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Human microRNA (miR-20b-5p) modulates Alzheimer’s disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences Alzheimer’s biomarkers

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Differentially expressed genes in Alzheimer’s disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1

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Laboratory evolution of a sortase enzyme that modifies amyloid-β protein

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Neuroprotective Mechanisms Mediated by CDK5 Inhibition

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Insulin mediated novel therapies for the treatment of Alzheimer's disease

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Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease

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Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways

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Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice

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Early-Stage Alzheimer’s Disease Is Associated with Simultaneous Systemic and Central Nervous System Dysregulation of Insulin-Linked Metabolic Pathways

de la Monte, S. M., Tong, M., Daiello, L. A., & Ott, B. R. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-180906 · Cited by 57 · see citing works

lncRNA XIST induces Aβ accumulation and neuroinflammation by the epigenetic repression of NEP in Alzheimer’s disease

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Genistein: A focus on several neurodegenerative diseases

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Recent advancement in therapeutic strategies for Alzheimer’s disease: Insights from clinical trials

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Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from Embelia ribes as a multitargeted anti‐Alzheimer agent

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Association of Angiotensin II–Stimulating Antihypertensive Use and Dementia Risk

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Photobiomodulation using a low-level light-emitting diode improves cognitive dysfunction in the 5XFAD mouse model of Alzheimer’s disease

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Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors

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Importance of endogenous compensatory vasoactive peptides in broadening the effects of inhibitors of the renin-angiotensin system for the treatment of heart failure

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Renin-angiotensin system and Alzheimer's disease pathophysiology: From the potential interactions to therapeutic perspectives.

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High-fat diet impairs cognitive function of zebrafish

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Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments

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Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors

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The neurobiology and therapeutic potential of multi-targeting β-secretase, glycogen synthase kinase 3β and acetylcholinesterase in Alzheimer’s disease

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A Small Molecule Inhibitor of Plasminogen Activator Inhibitor-1 Reduces Brain Amyloid-β Load and Improves Memory in an Animal Model of Alzheimer’s Disease

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Endogenous Murine Amyloid-β Peptide Assembles into Aggregates in the Aged C57BL/6J Mouse Suggesting These Animals as a Model to Study Pathogenesis of Amyloid-β Plaque Formation

Ahlemeyer, B., Halupczok, S., Rodenberg-Frank, E., Valerius, K.-P., & Baumgart‐Vogt, E. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170923 · Cited by 46 · see citing works

Interactions between Amyloid-Β Proteins and Human Brain Pericytes: Implications for the Pathobiology of Alzheimer’s Disease

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Association of Antihypertensives That Stimulate vs Inhibit Types 2 and 4 Angiotensin II Receptors With Cognitive Impairment

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In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan

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Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro

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The multifaceted role of WNT signaling in Alzheimer’s disease onset and age-related progression.

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Sacubitril/valsartan: A novel angiotensin receptor-neprilysin inhibitor

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5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer’s disease

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Accelerated Ovarian Failure as a Unique Model to Study Peri-Menopause Influence on Alzheimer’s Disease

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p38 MAPK Is a Major Regulator of Amyloid Beta-Induced IL-6 Expression in Human Microglia

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Valsartan/Sacubitril for Heart Failure

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Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight

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Vitamin E, Turmeric and Saffron in Treatment of Alzheimer’s Disease

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iPSC-derived three-dimensional brain organoid models and neurotropic viral infections

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Diosmetin as a promising natural therapeutic agent: In vivo, in vitro mechanisms, and clinical studies

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Influenza vaccine combined with moderate-dose PD1 blockade reduces amyloid-β accumulation and improves cognition in APP/PS1 mice

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