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Dairy consumption and risk of type 2 diabetes mellitus: a meta-analysis of cohort studies
Abstract
Background/objectives Milk intake is widely recommended for a healthy diet. Epidemiological studies have suggested that the consumption of dairy products may be associated with a reduction in type 2 diabetes mellitus (T2DM). A meta-analysis was conducted to elucidate the association between dairy products consumption and T2DM.Subjects/methods A systematical literature search was done through the Medline database and seven related cohort studies were identified. The adjusted relative risks (RRs) with the highest and the lowest categories from each study were extracted to calculate the combined RR. A least-square trend estimation was applied to assess the dose-response relationships.Results A combined RR of 0.86 (95% confidence interval (CI), 0.79-0.92) was revealed on T2DM risk associated to dairy intake, with little evidence of heterogeneity. For subgroup analysis, a combined RR was 0.82 (95% CI, 0.74-0.90), 1.00 (95% CI, 0.89-1.10), 0.95 (95% CI, 0.86-1.05) and 0.83 (95% CI, 0.74-0.93) for the intake of low-fat dairy, high-fat dairy, whole milk and yogurt, respectively. Dose-response analysis showed that T2DM risk could be reduced 5% for total dairy products and 10% for low-fat dairy products.Conclusion An inverse association of daily intake of dairy products, especially low-fat dairy, with T2DM was revealed, indicating a beneficial effect of dairy consumption in the prevention of T2DM development.
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“However, increased low-fat dairy consumption is associated with lower LDL-C, triglycerides, plasma insulin, insulin resistance, waist circumference, BMI, possibly blood pressure (BP); and reduced diabetes risk (174–182).”
From Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System (2015) · cites this paper as [182]
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Metadata
- Authors
- Tong, X., Dong, J.-Y., Wu, Z.-W., Li, W., & Qin, L.-Q.
- Affiliations
- Soochow University (CN)
- Corresponding author
- Qin, L-Q
- ORCID
- Tong, X
- Venue
- European Journal of Clinical Nutrition
- Published
- 2011-05-11
- Volume
- 65
- Issue
- 9
- Pages
- 1027-1031
- ISSN
- 0954-3007 (ISSN-L)
- 1476-5640
- OpenAlex
- W2125791761
- Cited by
- 337
- References
- 27
- Citations by year
- 2026: 3 · 2025: 15 · 2024: 16 · 2023: 18 · 2022: 22 · 2021: 22 · 2020: 18 · 2019: 28 · 2018: 20 · 2017: 32 · 2016: 26 · 2015: 36 · 2014: 30 · 2013: 29 · 2012: 17
- FWCI
- 3.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Vitamin D Research Studies
- Keywords
- dairy products, type 2 diabetes, low-fat dairy, whole milk, yogurt, high-fat dairy, milk consumption, diabetes prevention, dose-response relationship
- MeSH terms
- Dairy Products, Diabetes Mellitus, Type 2, Humans, Risk Factors, Cohort Studies, Confidence Intervals, Risk Assessment
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