The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.
Losing balance: the origin and impact of aneuploidy in cancer: ‘Exploring aneuploidy: the significance of chromosomal imbalance’ review series
Open accessAbstract
Most solid human tumours are aneuploid, that is, they contain an abnormal number of chromosomes. Paradoxically, however, aneuploidy has been reported to induce a stress response that suppresses cellular proliferation in vitro . Here, we review the progress in our understanding of the causes and effects of aneuploidy in cancer and discuss how, in specific contexts, aneuploidy can provide a growth advantage and facilitate cellular transformation. We also explore the emerging possibilities for targeting the cause or consequences of aneuploidy therapeutically.
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Metadata
- Authors
- Holland, A. J., & Cleveland, D. W.
- Venue
- EMBO reports
- Published
- 2012-05-08
- Volume
- 13
- Issue
- 6
- Pages
- 501-514
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- OpenAlex
- W2028666395
- Cited by
- 288
- References
- 177
- FWCI
- 13.83
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.