Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass
Abstract
Objective To identify factors contributing to the variation in weight loss after Roux-en-Y gastric bypass (RYGB).Design Cross-sectional study of patients with good (excess body mass index lost (EBL) >60%) and poor weight loss response (EBL <50%) >12 months after RYGB and a lean control group matched for age and gender.Materials and methods Sixteen patients with good weight loss response, 17 patients with poor weight loss response, and eight control subjects were included in the study. Participants underwent dual energy X-ray absorptiometry scan, indirect calorimetry and a 9 h multiple-meal test with measurements of glucose, insulin, total bile acids (TBA), glucagon-like peptide (GLP)-1, peptide YY3-36 (PYY), cholecystokinin (CCK), ghrelin, neurotensin and pancreatic polypeptide (PP) as well as assessment of early dumping and appetite.Results Suppression of hunger was more pronounced in the good than the poor responders in response to the multiple-meal test (P=0.006). In addition, the good responders had a larger release of GLP-1 (P=0.009) and a greater suppression of ghrelin (P=0.037) during the test, whereas the postprandial secretion of CCK was highest in the poor responders (P=0.005). PYY, neurotensin, PP and TBA release did not differ between the RYGB-operated groups. Compared with control subjects, patients had exaggerated release of GLP-1 (P<0.001), PYY (P=0.008), CCK (P=0.010) and neurotensin (P<0.001). Early dumping was comparable in the good and poor responders, but more pronounced than in controlled subjects. Differences in resting energy expenditure between the three groups were entirely explained by differences in body composition.Conclusion Favorable meal-induced changes in hunger and gut hormone release in patients with good compared with poor weight loss response support the role of gut hormones in the weight loss after RYGB.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
To date, the majority of the literature on weight regain physiology is based on dietary or surgically induced weight loss.
“To date, the majority of the literature on weight regain physiology is based on dietary or surgically induced weight loss.”
From The societal implications of using glucagon-like peptide-1 receptor agonists for the treatment of obesity (2025) · cites this paper as [82]
The Introduction (p. 1) and Discussion (pp. 5–6) address physiological differences in weight-loss response after gastric bypass, not the composition of the literature on weight-regain physiology. Searches for the claimed predominance of dietary or surgically induced weight-loss studies found no passage in our copy that assesses it. (LLM, conf=0.74)
Experimental — accuracy not yet measuredPatients with poor postoperative weight loss have greater concentrations of ghrelin and lower concentrations of GLP-1 and PYY than those with good weight loss.
“Furthermore, it has been shown that patients with poor postoperative weight loss have greater concentrations of ghrelin and lower concentrations of GLP-1 and PYY than those with good weight loss [126].”
From Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects (2020) · cites this paper as [126]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
New methods for calculating metabolic rate with special reference to protein metabolism
Weir, J. B. D. V. (1949) · The Journal of Physiology · doi:10.1113/jphysiol.1949.sp004363 · Cited by 5,608 · see citing works
Use and Abuse of HOMA Modeling
Wallace, T. M., Levy, J. C., & Matthews, D. R. (2004) · Diabetes Care · doi:10.2337/diacare.27.6.1487 · Cited by 5,114 · see citing works
Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects
Sjöström, L., Narbro, K., Sjöström, C. D., Karason, K., Larsson, B., Wedel, H., Lystig, T., Sullivan, M., Bouchard, C., Carlsson, B., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa066254 · Cited by 4,668 · see citing works
Gut hormone PYY3-36 physiologically inhibits food intake
Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351 · see citing works
Kahn, S. E. (2003) · Diabetologia · doi:10.1007/s00125-002-1009-0 · Cited by 2,166 · see citing works
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
Thomas, C., Gioiello, A., Noriega, L., Strehle, A., Oury, J., Rizzo, G., Macchiarulo, A., Yamamoto, H., Mataki, C., Pruzanski, M., et al. (2009) · Cell Metabolism · doi:10.1016/j.cmet.2009.08.001 · Cited by 1,885 · see citing works
Mechanick, J. I., Youdim, A., Jones, D. B., Garvey, W. T., Hurley, D. L., McMahon, M. M., Heinberg, L. J., Kushner, R., Adams, T. D., Shikora, S., et al. (2013) · Obesity · doi:10.1002/oby.20461 · Cited by 1,650 · see citing works
Tissue and Plasma Concentrations of Amidated and Glycine-Extended Glucagon-Like Peptide I in Humans
Ørskov, C., Rabenhøj, L., Wettergren, A., Kofod, H., & Holst, J. J. (1994) · Diabetes · doi:10.2337/diab.43.4.535 · Cited by 916 · see citing works
Self-citationGut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass
le Roux, C. W., Welbourn, R., Werling, M., Osborne, A., Kokkinos, A., Laurenius, A., Lönroth, H., Fändriks, L., Ghatei, M. A., Bloom, S. R., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e3180caa3e3 · Cited by 741 · see citing works
Weight Gain After Short- and Long-Limb Gastric Bypass in Patients Followed for Longer Than 10 Years
Christou, N. V., Look, D., & MacLean, L. D. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000217592.04061.d5 · Cited by 727 · see citing works
Long-term Weight Regain after Gastric Bypass: A 5-year Prospective Study
Magro, D. O., Geloneze, B., Delfini, R., Pareja, B. C., Callejas, F., & Pareja, J. C. (2008) · Obesity Surgery · doi:10.1007/s11695-007-9265-1 · Cited by 669 · see citing works
Verdich, C., Flint, A., Gutzwiller, J., Näslund, E. B., Beglinger, C., Hellström, P. M., Long, S. J., Morgan, L., Holst, J. J., & Astrup, A. V. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.9.7877 · Cited by 600 · see citing works
Self-citationPatti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, J. J., Badman, M. K., Maratos‐Flier, E., Mun, E. C., Pihlajamaki, J., et al. (2009) · Obesity · doi:10.1038/oby.2009.102 · Cited by 591 · see citing works
Peterli, R., Steinert, R. E., Wölnerhanssen, B. K., Peters, T. T. A., Christoffel-Courtin, C., Gass, M., Kern, B. E., von Fluee, M., & Beglinger, C. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0622-3 · Cited by 529 · see citing works
Morínigo, R., Moizé, V., Musri, M., Lacy, A. M., Navarro, S., Marín, J. L., Delgado, S., Casamitjana, R., & Vidal, J. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0904 · Cited by 397 · see citing works
Habib, A. M., Richards, P., Cairns, L. S., Rogers, G. J., Bannon, C. A. M., Parker, H. E., Morley, T. C. E., Yeo, G. S. H., Reimann, F. M., & Gribble, F. M. (2012) · Endocrinology · doi:10.1210/en.2011-2170 · Cited by 386 · see citing works
Pournaras, D. J., Glicksman, C., Vincent, R. P., Kuganolipava, S., Alaghband-Zadeh, J., Mahon, D., Bekker, J. H. R., Ghatei, M. A., Bloom, S. R., Walters, J. R. F., et al. (2012) · Endocrinology · doi:10.1210/en.2011-2145 · Cited by 383 · see citing works
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, J. J., & Patti, M. E. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0918 · Cited by 377 · see citing works
Self-citationPeptide YY3–36 and Glucagon-Like Peptide-17–36 Inhibit Food Intake Additively
Neary, N. M., Small, C. J., Druce, M. R., Park, A. J., Ellis, S. M., Semjonous, N. M., Dakin, C. L., Filipsson, K., Wang, F., Kent, A. S., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0237 · Cited by 371 · see citing works
Silva, A. D., Salem, V., Long, C. J., Makwana, A., Newbould, R. D., Rabiner, E. A., Ghatei, M. A., Bloom, S. R., Matthews, P. M., Beaver, J. D., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.09.010 · Cited by 351 · see citing works
Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, D., Almdal, T., Naver, L. S., Hvolris, L. E., et al. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0621-4 · Cited by 342 · see citing works
Self-citationOlbers, T., Bj??rkman, S., Lindroos, A., Maleckas, A., L??nn, L., Sj??str??m, L., & L??nroth, H. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000218085.25902.f8 · Cited by 340 · see citing works
Borg, C.-M., le Roux, C. W., Ghatei, M. A., Bloom, S. R., Patel, A. G., & Aylwin, S. J. B. (2006) · British journal of surgery · doi:10.1002/bjs.5227 · Cited by 318 · see citing works
Falkén, Y., Hellström, P. M., Holst, J. J., & Näslund, E. B. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2876 · Cited by 315 · see citing works
Self-citationJørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, D., Lindqvist Hansen, D., et al. (2012) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00073.2012 · Cited by 313 · see citing works
le Roux, C. W., Patterson, M., Vincent, R. P., Hunt, C., Ghatei, M. A., & Bloom, S. R. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1216 · Cited by 276 · see citing works
PANCREATIC-POLYPEPTIDE RESPONSE TO FOOD IN DUODENAL-ULCER PATIENTS BEFORE AND AFTER VAGOTOMY
Schwartz, T. W., STADIL, F., Chance, R. E., Rehfeld, J. F., Larson, L., & Moon, N. I. (1976) · The Lancet · doi:10.1016/s0140-6736(76)90065-9 · Cited by 252 · see citing works
Self-citationDifferential Effects of Gastric Bypass and Banding on Circulating Gut Hormone and Leptin Levels
Korner, J., Inabnet, W., Conwell, I. M., Taveras, C., Daud, A., Olivero‐Rivera, L., Restuccia, N. L., & Bessler, M. (2006) · Obesity · doi:10.1038/oby.2006.179 · Cited by 240 · see citing works
Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes
Prawitt, J., Caron, S., & Staels, B. (2011) · Current Diabetes Reports · doi:10.1007/s11892-011-0187-x · Cited by 239 · see citing works
ONE-HOUR BLOOD-XYLOSE TEST IN DIAGNOSIS OF COW'S MILK PROTEIN INTOLERANCE
Morin, C. L., Weber, A. M., Brochu, P., Buts, J., & Roy, C. (1979) · The Lancet · doi:10.1016/s0140-6736(79)91787-2 · Cited by 217 · see citing works
Sarwer, D., Dilks, R., & West-Smith, L. (2011) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2011.06.016 · Cited by 217 · see citing works
Das, S. K., Roberts, S. B., Crory, M. A. M., Hsu, L. G., Shikora, S. A., Kehayias, J. J., Dallal, G. E., & Saltzman, E. J. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.1.22 · Cited by 210 · see citing works
Gastric Bypass Increases Energy Expenditure in Rats
Bueter, M., Löwenstein, C., Olbers, T., Wang, M., Cluny, N. L., Bloom, S. R., Sharkey, K. A., Lutz, T. A., & le Roux, C. W. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.11.012 · Cited by 206 · see citing works
Changes in Eating Behaviour and Meal Pattern Following Roux-En-Y Gastric Bypass
Laurenius, A., Larsson, I., Bueter, M., Melanson, K. J., Bosaeus, I., Forslund, H. B., Lönroth, H., Fändriks, L., & Olbers, T. (2012) · International Journal of Obesity · doi:10.1038/ijo.2011.217 · Cited by 174 · see citing works
Changes in Patients’ Taste Acuity after Roux-en-Y Gastric Bypass for Clinically Severe Obesity
Burge, J. C., Schaumburg, J., Choban, P. S., DiSilvestro, R. A., & Flancbaum, L. (1995) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(95)00182-4 · Cited by 172 · see citing works
Miras, A. D., Jackson, R. N., Jackson, S. N., Goldstone, A. P., Olbers, T., Hackenberg, T., Spector, A. C., & le Roux, C. W. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.036921 · Cited by 162 · see citing works
Appetitive behavior after gastric bypass for obesity.
Halmi, K. A., Mason, E. E., Falk, J., & Stunkard, A. J. (1981) · PubMed · Cited by 148 · see citing works
Changes in neurohormonal gut peptides following bariatric surgery
Ochner, C. N., Gibson, C. D., Shanik, M. H., Goel, V., & Geliebter, A. (2010) · International Journal of Obesity · doi:10.1038/ijo.2010.132 · Cited by 135 · see citing works
Body Composition and Energy Metabolism Following Roux‐en‐Y Gastric Bypass Surgery
Tamboli, R. A., Hossain, H. A., Marks, P. A., Eckhauser, A. W., Rathmacher, J. A., Phillips, S. E., Buchowski, M. S., Chen, K. Y., & Abumrad, N. N. (2010) · Obesity · doi:10.1038/oby.2010.89 · Cited by 125 · see citing works
Early Changes in Ghrelin following Roux-en-Y Gastric Bypass: Influence of Vagal Nerve Functionality?
Sundbom, M., Holdstock, C., Engström, B. E., & Karlsson, F. A. (2007) · Obesity Surgery · doi:10.1007/s11695-007-9056-8 · Cited by 119 · see citing works
The Predominant Cholecystokinin in Human Plasma and Intestine Is Cholecystokinin-331
Rehfeld, J. F., Sun, G., Christensen, T., & Hillingsø, J. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.1.7148 · Cited by 116 · see citing works
Self-citationThe Predominant Cholecystokinin in Human Plasma and Intestine Is Cholecystokinin-33
Rehfeld, J. F. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.86.1.251 · Cited by 90 · see citing works
Self-citationDiagnostic Value of Dumping Provocation in Patients after Gastric Surgery
Van Der Kleij, F. G. H., Vecht, J., Lamers, C. B. H. W., & Masclee, A. A. M. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609036905 · Cited by 83 · see citing works
Postprandial changes in gut regulatory peptides in gastric bypass patients
Holdstock, C., Zethelius, B., Sundbom, M., Karlsson, F. A., & Engström, B. E. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.157 · Cited by 75 · see citing works
Ghrelin and appetite control in humans—Potential application in the treatment of obesity
Patterson, M., Bloom, S. R., & Gardiner, J. (2011) · Peptides · doi:10.1016/j.peptides.2011.07.021 · Cited by 72 · see citing works
How to measure cholecystokinin in tissue, plasma and cerebrospinal fluid
Rehfeld, J. F. (1998) · Regulatory Peptides · doi:10.1016/s0167-0115(98)00133-5 · Cited by 62 · see citing works
Self-citationEffect of Gastric Bypass and Gastric Banding on Proneurotensin Levels in Morbidly Obese Patients
Christ‐Crain, M., Stoeckli, R., Ernst, A. S., Morgenthaler, N. G., Bilz, S., Korbonits, M., Struck, J., Bergmann, A., Müller-Stich, B. P., & Keller, U. B. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0256 · Cited by 55 · see citing works
Ybarra, J., Bobbioni-Harsch, E., Chassot, G., Huber, O., Morel, P., Assimacopoulos‐Jeannet, F., & Golay, A. (2008) · Obesity Surgery · doi:10.1007/s11695-008-9748-8 · Cited by 41 · see citing works
Engström, B. E., Öhrvall, M., Sundbom, M., Lind, L., & Karlsson, F. A. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803440 · Cited by 37 · see citing works
Matzko, M. E., Argyropoulos, G. A., Wood, G. C., Chu, X., McCarter, R., Still, C. D., & Gerhard, G. S. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0631-2 · Cited by 36 · see citing works
Pérez, N., Serra, A., Granada, M. L., Rull, M., Alastrué, A., Navarro-Díaz, M., Romero, R., & Fernández-Llamazares, J. (2009) · Obesity Surgery · doi:10.1007/s11695-009-0035-0 · Cited by 36 · see citing works
Mechanisms of Weight Loss after Gastric Bypass and Gastric Banding
Bueter, M., Ashrafian, H., & le Roux, C. W. (2009) · Obesity Facts · doi:10.1159/000232383 · Cited by 35 · see citing works
Cholecystokinin as satiety signal.
Jf, R. (1981) · PubMed · Cited by 14 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- 30 Mechanick JI, Kushner RF, Sugerman HJ, Gonzalez-Campoy JM, Collazo-Clavell ML, Guven S et al. American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic and Bariatric Surgery Medical Guidelines for Clinical Practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric. Obesity (Silver Spring) 2008; 4 : S109-S184.
Cited by
Sorted by citations
Chávez-Talavera, O., Tailleux, A., Lefebvre, P., & Staels, B. (2017) · Gastroenterology · doi:10.1053/j.gastro.2017.01.055 · Cited by 970 · see citing works
Altered gut and adipose tissue hormones in overweight and obese individuals: Cause or consequence?
Lean, M. E. J., & Malkova, D. (2016) · International Journal of Obesity · doi:10.1038/ijo.2015.220 · Cited by 253 · see citing works
Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Jensen, M. H., Gabe, M. B. N., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., et al. (2019) · Diabetes · doi:10.2337/db18-1123 · Cited by 193 · see citing works
Self-citationMiras, A. D., Pérez-Pevida, B., Aldhwayan, M., Kamocka, A., McGlone, E. R., Al-Najim, W., Chahal, H., Batterham, R. L., McGowan, B., Khan, O., et al. (2019) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(19)30157-3 · Cited by 190 · see citing works
Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Wewer Albrechtsen, N. J., Rehfeld, J. F., Hartmann, B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.121 · Cited by 185 · see citing works
Self-citationMechanism Underlying the Weight Loss and Complications of Roux-en-Y Gastric Bypass. Review
Abdeen, G., & le Roux, C. (2016) · Obesity Surgery · doi:10.1007/s11695-015-1945-7 · Cited by 162 · see citing works
Bile acids and bariatric surgery
Albaugh, V. L., Banan, B., Ajouz, H., Abumrad, N. N., & Flynn, C. R. (2017) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2017.04.001 · Cited by 148 · see citing works
Weight Regain After Gastric Bypass: Influence of Gut Hormones
Santo, M. A., Riccioppo, D., Pajecki, D., Kawamoto, F., de Cleva, R., Antonangelo, L., Marçal, L., & Cecconello, I. (2016) · Obesity Surgery · doi:10.1007/s11695-015-1908-z · Cited by 145 · see citing works
Wharton, S., Kuk, J. L., Luszczynski, M., Kamran, E., & Christensen, R. A. G. (2019) · Clinical Obesity · doi:10.1111/cob.12323 · Cited by 144 · see citing works
Biological Control of Appetite: A Daunting Complexity
MacLean, P. S., Blundell, J. E., Mennella, J. A., & Batterham, R. L. (2017) · Obesity · doi:10.1002/oby.21771 · Cited by 140 · see citing works
Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36
Iepsen, E. W., Lundgren, J., Holst, J. J., Madsbad, S., & Torekov, S. S. (2016) · European Journal of Endocrinology · doi:10.1530/eje-15-1116 · Cited by 101 · see citing works
Self-citationMakaronidis, J. M., Neilson, S., Cheung, W.-H., Tymoszuk, U., Pucci, A., Finer, N., Doyle, J., Hashemi, M., Elkalaawy, M., Adamo, M., et al. (2016) · Appetite · doi:10.1016/j.appet.2016.07.029 · Cited by 94 · see citing works
Perakakis, N., Kokkinos, A., Peradze, N., Tentolouris, N., Ghaly, W., Pilitsi, E., Upadhyay, J., Alexandrou, A., & Mantzoros, C. S. (2019) · Metabolism · doi:10.1016/j.metabol.2019.153997 · Cited by 93 · see citing works
Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer
Sinclair, P., Brennan, D. J., & le Roux, C. W. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0057-y · Cited by 91 · see citing works
Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects
Biobaku, F., Ghanim, H., Monte, S. V., Caruana, J. A., & Dandona, P. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa049 · Cited by 68 · see citing works
GIP and GLP-1 receptor antagonism during a meal in healthy individuals
Gasbjerg, L. S., Helsted, M. M., Hartmann, B., Sparre-Ulrich, A. H., Veedfald, S., Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, M. B., Vilsbøll, T., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgz175 · Cited by 68 · see citing works
Self-citationDo Gut Hormones Contribute to Weight Loss and Glycaemic Outcomes after Bariatric Surgery?
Papamargaritis, D., & le Roux, C. W. (2021) · Nutrients · doi:10.3390/nu13030762 · Cited by 68 · see citing works
Huber, H., Schieren, A., Holst, J. J., & Simon, M.-C. (2024) · The American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2024.01.007 · Cited by 62 · see citing works
Self-citationIncretin Hormones, Obesity and Gut Microbiota
Angelini, G., Russo, S., & Mingrone, G. (2024) · Peptides · doi:10.1016/j.peptides.2024.171216 · Cited by 47 · see citing works
Tam, C. S., Redman, L. M., Greenway, F., LeBlanc, K. A., Haussmann, M. G., & Ravussin, E. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-1814 · Cited by 42 · see citing works
Protein- and Calcium-Mediated GLP-1 Secretion: A Narrative Review
Watkins, J. D., Koumanov, F., & Gonzalez, J. T. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab078 · Cited by 40 · see citing works
Change in Emotional Eating After Bariatric Surgery: Systematic Review and Meta-Analysis
Wong, L. Y., Zafari, N., Churilov, L., Stammers, L., Price, S., Ekinci, E. I., & Sumithran, P. (2020) · BJS Open · doi:10.1002/bjs5.50318 · Cited by 29 · see citing works
Lampropoulos, C., Alexandrides, T., Tsochatzis, S., Kehagias, D., & Kehagias, I. (2021) · Obesity Surgery · doi:10.1007/s11695-021-05568-7 · Cited by 30 · see citing works
Scragg, J., Koutoukidis, D. A., Dirksen, C., Heitmann, B. L., & Jebb, S. A. (2025) · Med · doi:10.1016/j.medj.2025.100805 · Cited by 16 · see citing works
Self-citation
- Authors
- Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, D., Hartmann, B., Rehfeld, J. F., Damgaard, M., Madsen, J. L., Madsbad, S., Holst, J. J., & Hansen, D. L.
- Affiliations
- University of Copenhagen (DK)
- Novo Nordisk (Denmark) (DK)
- Corresponding author
- Dirksen, C
- ORCID
- Venue
- International Journal of Obesity
- Published
- 2013-02-19
- Volume
- 37
- Issue
- 11
- Pages
- 1452-1459
- ISSN
- 0307-0565 (ISSN-L)
- 1476-5497
- OpenAlex
- W2049394141
- Cited by
- 276
- References
- 53
- Citations by year
- 2026: 4 · 2025: 18 · 2024: 16 · 2023: 16 · 2022: 21 · 2021: 25 · 2020: 21 · 2019: 19 · 2018: 24 · 2017: 27 · 2016: 31 · 2015: 30 · 2014: 14 · 2013: 9
- FWCI
- 27.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- International Journal of Obesity (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
- Keywords
- Roux-en-Y gastric bypass, weight loss response, gastrointestinal hormones, resting energy expenditure, ghrelin, glucagon-like peptide-1, cholecystokinin, peptide YY, neurotensin, pancreatic polypeptide, total bile acids, appetite suppression, body composition, bariatric surgery
- MeSH terms
- Appetite Regulation, Bile Acids and Salts, Blood Glucose, Cholecystokinin, Cross-Sectional Studies, Dumping Syndrome, Energy Metabolism, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neurotensin, Obesity, Morbid, Gastric Bypass, Weight Loss, Absorptiometry, Photon, Body Mass Index, Treatment Outcome, Peptide YY, Glucagon-Like Peptide 1, Ghrelin
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
