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Applying machine learning to predict viral assembly for adeno-associated virus capsid libraries

Marques, A. D., Kummer, M., Kondratov, O., Banerjee, A., Moskalenko, O. V., & Zolotukhin, S. (2020) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2020.11.017 · Cited by 55

Gene delivery methods in cardiac gene therapy

Ishikawa, K., Tilemann, L. M., Fish, K. M., & Hajjar, R. J. (2011) · The Journal of Gene Medicine · doi:10.1002/jgm.1609 · Cited by 55

Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry

Large, E. E., Silveria, M., Zane, G. M., Weerakoon, O., & Chapman, M. S. (2021) · Viruses · doi:10.3390/v13071336 · Cited by 57

Immune responses to adeno-associated virus type 2 encoding channelrhodopsin-2 in a genetically blind rat model for gene therapy

Sugano, E., Isago, H., Wang, Z., Murayama, N., Tamai, M., & Tomita, H. (2010) · Gene Therapy · doi:10.1038/gt.2010.140 · Cited by 55

Synthetic virology: engineering viruses for gene delivery

Guenther, C. M., Kuypers, B. E., Lam, M. T., Robinson, T. M., Zhao, J. X., & Suh, J. (2014) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1287 · Cited by 56

Next-generation AAV vectors for clinical use: an ever-accelerating race

Weinmann, J., & Grimm, D. (2017) · Virus Genes · doi:10.1007/s11262-017-1502-7 · Cited by 54

Immune responses to gene editing by viral and non-viral delivery vectors used in retinal gene therapy

Ren, D., Fisson, S., Dalkara, D., & Ail, D. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14091973 · Cited by 52

DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain

Zhou, L., Ni, Y.-Y., Piñeyro, P. E., Sanford, B. J., Cossaboom, C. M., Dryman, B. A., Huang, Y., Cao, D., & Meng, X. (2012) · Virology · doi:10.1016/j.virol.2012.09.005 · Cited by 52

Optimization of AAV vectors to target persistent viral reservoirs

Colón-Thillet, R., Jerome, K. R., & Stone, D. (2021) · Virology Journal · doi:10.1186/s12985-021-01555-7 · Cited by 50

Optimization of stealth adeno-associated virus vectors by randomization of immunogenic epitopes

Maersch, S., Huber, A., Büning, H., Hallek, M., & Perabo, L. (2010) · Virology · doi:10.1016/j.virol.2009.10.021 · Cited by 50

Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy

Nance, M. E., & Duan, D. (2015) · Human Gene Therapy · doi:10.1089/hum.2015.107 · Cited by 52

Random Insertion of mCherry Into VP3 Domain of Adeno-associated Virus Yields Fluorescent Capsids With no Loss of Infectivity

Judd, J., Wei, F., Nguyen, P. Q., Tartaglia, L. J., Agbandje‐McKenna, M., Silberg, J. J., & Suh, J. (2012) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2012.46 · Cited by 53

Directed evolution of adeno-associated virus for glioma cell transduction

Maguire, C. A., Gianni, D., Meijer, D. H., Shaket, L. A., Wakimoto, H., Rabkin, S. D., Gao, G., & Sena‐Esteves, M. (2009) · Journal of Neuro-Oncology · doi:10.1007/s11060-009-9972-7 · Cited by 52

CAV-2 Vector Development and Gene Transfer in the Central and Peripheral Nervous Systems

Rio, D. D., Beucher, B., Lavigne, M., Wehbi, A., Dopeso‐Reyes, I. G., Saggio, I., & Kremer, E. J. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00071 · Cited by 53

In This Issue

(2008) · Molecular Therapy · doi:10.1038/mt.2008.139

743. Directed Evolution of Adeno-Associated Virus (AAV) by DNA Shuffling Yields Enhanced Gene Delivery Vectors

Li, W., & Samulski, J. R. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2006.08.825 · Cited by 2

Dissection and optimization of Adeno-associated virus (AAV) DNA family shuffling technology: The journey is the reward

Herrmann, A.-K. (2018) · heiDOK (Heidelberg University) · doi:10.11588/heidok.00025503

Secrets to finding the ideal mate:New insights into parameters that govern successful Adeno-associated virus (AAV) vector evolution

Kienle, E. (2014) · heiDOK (Heidelberg University) · doi:10.11588/heidok.00017851 · Cited by 1

Engineering and Evolution of Synthetic Adeno-Associated Virus (AAV) Gene Therapy Vectors via DNA Family Shuffling

Kienle, E., Senís, E., Börner, K., Niopek, D., Wiedtke, E., Große, S., & Grimm, D. (2012) · Journal of Visualized Experiments · doi:10.3791/3819 · Cited by 31