Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

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8. mRNA-Based Protein Replacement Therapy for the Heart
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9. Biomaterials for mRNA delivery
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10. Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
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14. mRNA mediates passive vaccination against infectious agents, toxins, and tumors
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15. Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code
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16. Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
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18. Lipid nanoparticles for short interfering RNA delivery
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19. Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics: Getting the message across
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20. Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins
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21. Breaking the final barrier: Evolution of cationic and ionizable lipid structure in lipid nanoparticles to escape the endosome
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22. Effects of Chemically Modified Messenger RNA on Protein Expression
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23. Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics—An innate immune system standpoint
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24. Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’
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25. Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency
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27. Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
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28. Synthetic mRNA Encoding VEGF-A in Patients Undergoing Coronary Artery Bypass Grafting: Design of a Phase 2a Clinical Trial
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29. Modulated Protonation of Side Chain Aminoethylene Repeats in N-Substituted Polyaspartamides Promotes mRNA Transfection
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30. Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac and Tol2 for Genome Engineering
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31. Non-viral delivery of the CRISPR/Cas system: DNA versus RNA versus RNP
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32. Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia
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35. Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety
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37. Ionizable Amino‐Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino‐Alcohols for Tissue Selective mRNA Delivery
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47. Responsive Nanocarriers as an Emerging Platform for Cascaded Delivery of Nucleic Acids to Cancer
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48. Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life
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55. Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells
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56. Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon
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57. A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs
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58. mRNA therapeutics deliver a hopeful message
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59. Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment
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61. Single-cell mRNA transfection studies: Delivery, kinetics and statistics by numbers
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