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Mutations in the deubiquitinase gene USP8 cause Cushing's disease
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Cites
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
Roberts, P. J., & Der, C. J. (2007) · Oncogene · doi:10.1038/sj.onc.1210422 · Cited by 2,788
Breaking the chains: structure and function of the deubiquitinases
Komander, D., Clague, M. J., & Urbé, S. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2731 · Cited by 1,969
The ubiquitin-proteasome proteolytic pathway
Ciechanover, A. (1994) · Cell · doi:10.1016/0092-8674(94)90396-4 · Cited by 1,791
DNA Repair by ERCC1 in Non–Small-Cell Lung Cancer and Cisplatin-Based Adjuvant Chemotherapy
Olaussen, K. A., Dunant, A., Fouret, P., Brambilla, E., André, F., Haddad, V., Taranchon, E., Filipits, M., Pirker, R., Popper, H. H., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa060570 · Cited by 1,727
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.
Reyes-Turcu, F. E., Ventii, K. H., & Wilkinson, K. D. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.78.082307.091526 · Cited by 1,396
Cushing, H. (1964) · Journal of Neurosurgery · doi:10.3171/jns.1964.21.4.0318 · Cited by 851
Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
Kulathu, Y., & Komander, D. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3394 · Cited by 619
Regulation of monoubiquitinated PCNA by DUB autocleavage
Huang, T. T., Nijman, S. M. B., Mirchandani, K. D., Galardy, P. J., Cohn, M. A., Haas, W., Gygi, S. P., Ploegh, H. L., Bernards, R., & D'Andrea, A. D. (2006) · Nature Cell Biology · doi:10.1038/ncb1378 · Cited by 581
Huang, F., Kirkpatrick, D., Jiang, X., Gygi, S., & Sorkin, A. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.02.018 · Cited by 497
Pathogenesis of pituitary tumors
Melmed, S. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2011.40 · Cited by 466
Constitutive activation of PKA catalytic subunit in adrenal Cushing’s syndrome
Beuschlein, F., Fassnacht, M., Assié, G., Calebiro, D., Stratakis, C. A., Osswald, A., Ronchi, C. L., Wieland, T., Sbiera, S., Faucz, F. R., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1310359 · Cited by 443
Self-citationNovel Dimeric Nur77 Signaling Mechanism in Endocrine and Lymphoid Cells
Philips, A., Lesage, S., Gingras, R., Maira, M.-H., Gauthier, Y., Hugo, P., & Drouin, J. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.10.5946 · Cited by 372
Orchestration of cell surface proteins by Rab11
Welz, T., Wellbourne-Wood, J., & Kerkhoff, E. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.02.004 · Cited by 315
The role of ubiquitylation in receptor endocytosis and endosomal sorting
Haglund, K., & Dikic, I. (2012) · Journal of Cell Science · doi:10.1242/jcs.091280 · Cited by 313
Row, P. E., Prior, I. A., McCullough, J., Clague, M. J., & Urbé, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m512615200 · Cited by 264
EGFR as a therapeutic target for human, canine, and mouse ACTH-secreting pituitary adenomas
Fukuoka, H., Cooper, O., Ben-Shlomo, A., Mamelak, A., Ren, S.-G., Bruyette, D., & Melmed, S. (2011) · Journal of Clinical Investigation · doi:10.1172/jci60417 · Cited by 254
Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors
Goh, G., Scholl, U. I., Healy, J. M., Choi, M., Prasad, M. L., Nelson-Williams, C., Kunstman, J. W., Korah, R., Suttorp, A.-C., Dietrich, D., et al. (2014) · Nature Genetics · doi:10.1038/ng.2956 · Cited by 251
Mizuno, E., Iura, T., Mukai, A., Yoshimori, T., Kitamura, N., & Komada, M. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-06-0560 · Cited by 248
Self-citationActivating hotspot L205R mutation in PRKACA and adrenal Cushing’s syndrome
Cao, Y., He, M., Gao, Z., Peng, Y., Li, Y., Li, L., Zhou, W., Li, X., Zhong, X., Lei, Y., et al. (2014) · Science · doi:10.1126/science.1249480 · Cited by 232
Kato, M., Miyazawa, K., & Kitamura, N. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m007251200 · Cited by 213
Stratakis, C., Tichomirowa, M., Boikos, S., Azevedo, M., Lodish, M., Martari, M., Verma, S., Daly, A., Raygada, M., Keil, M., et al. (2010) · Clinical Genetics · doi:10.1111/j.1399-0004.2010.01406.x · Cited by 210
Recurrent somatic mutations underlie corticotropin-independent Cushing’s syndrome
Sato, Y., Maekawa, S., Ishii, R., Sanada, M., Morikawa, T., Shiraishi, Y., Yoshida, K., Nagata, Y., Sato-Otsubo, A., Yoshizato, T., et al. (2014) · Science · doi:10.1126/science.1252328 · Cited by 209
Niendorf, S., Oksche, A., Kisser, A., Löhler, J., Prinz, M., Schorle, H., Feller, S., Lewitzky, M., Horak, I., & Knobeloch, K.-P. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.01566-06 · Cited by 207
Retinoic acid prevents experimental Cushing syndrome
Páez-Pereda, M., Kovalovsky, D., Hopfner, U., Theodoropoulou, M., Pagotto, U., Uhl, E., Losa, M., Stalla, J., Grübler, Y., Missale, C., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11098 · Cited by 190
Self-citationGovernance of Endocytic Trafficking and Signaling by Reversible Ubiquitylation
Clague, M. J., Liu, H., & Urbé, S. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.08.011 · Cited by 177
Bowers, K., Piper, S. C., Edeling, M. A., Gray, S. R., Owen, D. J., Lehner, P. J., & Luzio, J. P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m508632200 · Cited by 166
Komada, M., Masaki, R., Yamamoto, A., & Kitamura, N. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.33.20538 · Cited by 161
Self-citationUBPY-mediated Epidermal Growth Factor Receptor (EGFR) De-ubiquitination Promotes EGFR Degradation
Alwan, H. A. J., & van Leeuwen, J. E. M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m604711200 · Cited by 140
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
Mukai, A., Yamamoto‐Hino, M., Awano, W., Watanabe, W., Komada, M., & Goto, S. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.100 · Cited by 138
Self-citationA Deubiquitinating Enzyme UBPY Regulates the Level of Protein Ubiquitination on Endosomes
Mizuno, E., Kobayashi, K., Yamamoto, A., Kitamura, N., & Komada, M. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00452.x · Cited by 120
Self-citationTheodoropoulou, M., Arzberger, T., Grübler, Y., Jaffrain‐Rea, M., Schlegel, J., Schaaf, L., Petrangeli, E., Losa, M., Stalla, G. K., & Pagotto, U. (2004) · Journal of Endocrinology · doi:10.1677/joe.1.05616 · Cited by 105
Self-citationMizuno, E., Kitamura, N., & Komada, M. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.07.028 · Cited by 98
Self-citationKetoconazole Inhibits Corticotropic Cell Functionin Vitro*
Stalla, G. K., Stalla, J., HUBER, M., Loeffler, J., Höllt, V., von Werder, K., & Müller, O. A. (1988) · Endocrinology · doi:10.1210/endo-122-2-618 · Cited by 76
The ubiquitin code and its decoding machinery in the endocytic pathway
Tanno, H., & Komada, M. (2013) · The Journal of Biochemistry · doi:10.1093/jb/mvt028 · Cited by 72
Self-citationLiu, B., Hammer, G. D., Rubinstein, M., Mortrud, M. T., & Low, M. J. (1992) · Molecular and Cellular Biology · doi:10.1128/mcb.12.9.3978 · Cited by 67
Ishida, M., Ohbayashi, N., Maruta, Y., Ebata, Y., & Fukuda, M. (2012) · Journal of Cell Science · doi:10.1242/jcs.109314 · Cited by 49
Morino, C., Kato, M., Yamamoto, A., Mizuno, E., Hayakawa, A., Komada, M., & Kitamura, N. (2004) · Experimental Cell Research · doi:10.1016/j.yexcr.2004.03.038 · Cited by 33
Self-citationThe molecular pathogenesis of corticotroph tumours
Dworakowska, D., & Grossman, A. B. (2011) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2011.02621.x · Cited by 30
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Lacroix, A., Feelders, R. A., Stratakis, C. A., & Nieman, L. K. (2015) · The Lancet · doi:10.1016/s0140-6736(14)61375-1 · Cited by 1,777
Consensus on diagnosis and management of Cushing's disease: a guideline update
Fleseriu, M., Auchus, R., Bancos, I., Ben-Shlomo, A., Bertherat, J., Biermasz, N. R., Boguszewski, C. L., Bronstein, M. D., Buchfelder, M., Carmichael, J. D., et al. (2021) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(21)00235-7 · Cited by 953
Self-citationDeubiquitylating enzymes and drug discovery: emerging opportunities
Harrigan, J. A., Jacq, X., Martin, N. M., & Jackson, S. P. (2018) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2017.152 · Cited by 940
Breaking the chains: deubiquitylating enzyme specificity begets function
Clague, M. J., Urbé, S., & Komander, D. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0099-1 · Cited by 832
Immunological impact of cell death signaling driven by radiation on the tumor microenvironment
Rodriguez-Ruiz, M. E., Vitale, I., Harrington, K. J., Melero, I., & Galluzzi, L. (2020) · Nature Immunology · doi:10.1038/s41590-019-0561-4 · Cited by 385
Metadata
- Authors
- Reincke, M., Sbiera, S., Hayakawa, A., Theodoropoulou, M., Osswald, A., Beuschlein, F., Meitinger, T., Mizuno-Yamasaki, E., Kawaguchi, K., Saeki, Y., Tanaka, K., Wieland, T., Graf, E., Saeger, W., Ronchi, C. L., Allolio, B., Buchfelder, M., Strom, T. M., Fassnacht, M., & Komada, M.
- Venue
- Nature Genetics
- Published
- 2014-12-08
- Volume
- 47
- Issue
- 1
- Pages
- 31-38
- ISSN
- 1061-4036 (ISSN-L)
- 1546-1718
- OpenAlex
- W1975715657
- Cited by
- 599
- References
- 39
- FWCI
- 28.72
- Type
- journal article
- Language
- en
- Open access
- closed
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