Targeting inflammation in the treatment of type 2 diabetes: time to start

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Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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Rosuvastatin to Prevent Vascular Events in Men and Women With Elevated C-Reactive Protein

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

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Inflammation in Atherosclerosis

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Mammalian Sirtuins: Biological Insights and Disease Relevance

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Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of <i>Ikkβ</i>

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Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

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Islet cell failure in type 2 diabetes

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Leptin-regulated endocannabinoids are involved in maintaining food intake

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CCR2 modulates inflammatory and metabolic effects of high-fat feeding

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Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

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Relationship between Adipocyte Size and Adipokine Expression and Secretion

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The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

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Monocyte chemoattractant protein 1 in obesity and insulin resistance

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Five stages of evolving beta-cell dysfunction during progression to diabetes

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Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets

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Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

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Nutrient sensing and inflammation in metabolic diseases

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A Subpopulation of Macrophages Infiltrates Hypertrophic Adipose Tissue and Is Activated by Free Fatty Acids via Toll-like Receptors 2 and 4 and JNK-dependent Pathways

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Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

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β-Cell Glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes.

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Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

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Increased Number of Islet-Associated Macrophages in Type 2 Diabetes

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Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

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The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

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A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance

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Islet Amyloid: A Critical Entity in the Pathogenesis of Type 2 Diabetes

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High White Blood Cell Count Is Associated With a Worsening of Insulin Sensitivity and Predicts the Development of Type 2 Diabetes

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Metformin Inhibits Proinflammatory Responses and Nuclear Factor-κB in Human Vascular Wall Cells

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Psoriasis Severity and the Prevalence of Major Medical Comorbidity

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Blocking Interleukin-1β Induces a Healing-Associated Wound Macrophage Phenotype and Improves Healing in Type 2 Diabetes

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Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

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