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Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis
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Cites
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans
Saito, M., Okamatsu-Ogura, Y., Matsushita, M., Watanabe, K., Yoneshiro, T., Nio-Kobayashi, J., Iwanaga, T., Miyagawa, M., Kameya, T., Nakada, K., et al. (2009) · Diabetes · doi:10.2337/db09-0530 · Cited by 1,848
Nichols, D. E., & Nichols, C. D. (2008) · Chemical Reviews · doi:10.1021/cr078224o · Cited by 895
Roberts, L. D., Boström, P., O’Sullivan, J. F., Schinzel, R. T., Lewis, G. D., Dejam, A., Lee, Y.-K., Palma, M. J., Calhoun, S., Georgiadi, A., et al. (2014) · Cell Metabolism · doi:10.1016/j.cmet.2013.12.003 · Cited by 643
Paulmann, N., Grohmann, M., Voigt, J.-P., Bert, B., Vowinckel, J., Bader, M., Skelin, M., Jevšek, M., Fink, H., Rupnik, M., et al. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000229 · Cited by 404
Li, Z., Chalazonitis, A., Huang, Y.-Y., Mann, J. J., Margolis, K. G., Yang, Q. M., Kim, D. O., Cote, F., Mallet, J., & Gershon, M. D. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6684-10.2011 · Cited by 403
Metabolomic Analysis of Livers and Serum from High-Fat Diet Induced Obese Mice
Kim, H.-J., Kim, J. H., Noh, S., Hur, H. J., Sung, M. J., Hwang, J.-T., Park, J. H., Yang, H. J., Kim, M.-S., Kwon, D. Y., et al. (2011) · Journal of Proteome Research · doi:10.1021/pr100892r · Cited by 376
Self-citationSteinberg, G. R., O'Neill, H. M., Dzamko, N. L., Galic, S., Naim, T., Koopman, R., Jørgensen, S. B., Honeyman, J., Hewitt, K., Chen, Z.-P., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.102434 · Cited by 164
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Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
Agus, A., Planchais, J., & Sokol, H. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.05.003 · Cited by 3,180
Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health
Cervenka, I., Agudelo, L. Z., & Ruas, J. L. (2017) · Science · doi:10.1126/science.aaf9794 · Cited by 1,382
Gut microbiota-derived metabolites as central regulators in metabolic disorders
Agus, A., Clément, K., & Sokol, H. (2021) · Gut · doi:10.1136/gutjnl-2020-323071 · Cited by 1,347
From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways
Rogers, G. B., Keating, D. J., Young, R. L., Wong, M.-L., Licinio, J., & Wesselingh, S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.50 · Cited by 969
Jenkins, T., Nguyen, J., Polglaze, K., & Bertrand, P. (2016) · Nutrients · doi:10.3390/nu8010056 · Cited by 904
Nonalcoholic fatty liver disease
Brunt, E. M., Wong, V. W.-S., Nobili, V., Day, C. P., Sookoian, S., Maher, J. J., Bugianesi, E., Sirlin, C. B., Neuschwander-Tetri, B. A., & Rinella, M. E. (2015) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2015.80 · Cited by 818
Kynurenine pathway metabolism and the microbiota-gut-brain axis
Kennedy, P. J., Cryan, J. F., Dinan, T. G., & Clarke, G. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.07.002 · Cited by 724
Natividad, J. M., Agus, A., Planchais, J., Lamas, B., Jarry, A. C., Martin, R., Michel, M.-L., Chong-Nguyen, C., Roussel, R., Straube, M., et al. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.07.001 · Cited by 642
The Influence of the Gut Microbiome on Host Metabolism Through the Regulation of Gut Hormone Release
Martin, A. M., Sun, E. W., Rogers, G. B., & Keating, D. J. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00428 · Cited by 384
From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators
Han, H., Yi, B., Zhong, R., Wang, M., Zhang, S., Ma, J., Yin, Y., Yin, J., Chen, L., & Zhang, H. (2021) · Microbiome · doi:10.1186/s40168-021-01093-y · Cited by 292
Non-conventional features of peripheral serotonin signalling — the gut and beyond
Spohn, S. N., & Mawe, G. M. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.51 · Cited by 282
The diverse metabolic roles of peripheral serotonin
Martin, A. M., Young, R. L., Leong, L., Rogers, G. B., Spencer, N. J., Jessup, C. F., & Keating, D. J. (2017) · Endocrinology · doi:10.1210/en.2016-1839 · Cited by 261
Tryptophan Dietary Impacts Gut Barrier and Metabolic Diseases
Taleb, S. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02113 · Cited by 236
Clostridium ramosum regulates enterochromaffin cell development and serotonin release
Mandić, A. D., Woting, A., Jaenicke, T., Sander, A., Sabrowski, W., Rolle-Kampcyk, U., von Bergen, M., & Blaut, M. (2019) · Scientific Reports · doi:10.1038/s41598-018-38018-z · Cited by 150
The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
Bany Bakar, R., Reimann, F., & Gribble, F. M. (2023) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-023-00830-y · Cited by 144
Ghesmati, Z., Rashid, M., Fayezi, S., Gieseler, F., Alizadeh, E., & Darabi, M. (2024) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09850-0 · Cited by 139
Low protein diets produce divergent effects on energy balance
Pezeshki, A., Zapata, R. C., Singh, A., Yee, N. J., & Chelikani, P. K. (2016) · Scientific Reports · doi:10.1038/srep25145 · Cited by 103
Augmented capacity for peripheral serotonin release in human obesity
Young, R. L., Lumsden, A. L., Martin, A. M., Schober, G., Pezos, N., Thazhath, S. S., Isaacs, N. J., Cvijanovic, N., Sun, E. W. L., Wu, T., et al. (2018) · International Journal of Obesity · doi:10.1038/s41366-018-0047-8 · Cited by 87
Antipsychotics and glucose metabolism: how brain and body collide
Kowalchuk, C., Castellani, L. N., Chintoh, A., Remington, G., Giacca, A., & Hahn, M. K. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00164.2018 · Cited by 85
Smith, B. K., Ford, R. J., Desjardins, E. M., Green, A. E., Hughes, M. C., Houde, V. P., Day, E. A., Marcinko, K., Crane, J. D., Mottillo, E. P., et al. (2016) · Diabetes · doi:10.2337/db16-0564 · Cited by 79
Self-citationThe Regulation of Peripheral Metabolism by Gut-Derived Hormones
Sun, E. W. L., Martin, A. M., Young, R. L., & Keating, D. J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00754 · Cited by 71
The nutrient-sensing repertoires of mouse enterochromaffin cells differ between duodenum and colon
Martin, A. M., Lumsden, A. L., Young, R. L., Jessup, C. F., Spencer, N. J., & Keating, D. J. (2017) · Neurogastroenterology & Motility · doi:10.1111/nmo.13046 · Cited by 74
Lactation improves pancreatic β cell mass and function through serotonin production
Moon, J. H., Kim, H., Kim, H., Park, J., Choi, W., Choi, W., Hong, H. J., Ro, H.-J., Jun, S., Choi, S. H., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay0455 · Cited by 67
Enteroendocrine Cells: Metabolic Relays between Microbes and Their Host
Plovier, H., & Cani, P. D. (2017) · Endocrine Development · doi:10.1159/000475736 · Cited by 36
BANANA PEEL FLAKES ALLEVIATE BLOOD GLUCOSE AND STRESS IN A DOSE-DEPENDENT MANNER
MELIALA, A., SUMIWI, Y. A. A., NARWIDINA, P., RINI, S. L. S., & SETYANINGSIH, W. (2020) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2020v12i8.37659 · Cited by 10
Metadata
- Authors
- Crane, J. D., Palanivel, R., Mottillo, E. P., Bujak, A. L., Wang, H., Ford, R. J., Collins, A., Blümer, R. M., Fullerton, M. D., Yabut, J. M., Kim, J. J., Ghia, J.-E., Hamza, S. M., Morrison, K. M., Schertzer, J. D., Dyck, J. R. B., Khan, W. I., & Steinberg, G. R.
- Venue
- Nature Medicine
- Published
- 2014-12-08
- Volume
- 21
- Issue
- 2
- Pages
- 166-172
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1996234987
- Cited by
- 490
- References
- 7
- FWCI
- 20.99
- Type
- journal article
- Language
- en
- Open access
- green
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