From gut microbiota to host appetite: gut microbiota-derived metabolites as key regulators

The gut microbiota as an environmental factor that regulates fat storage

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The Microbiota-Gut-Brain Axis

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Richness of human gut microbiome correlates with metabolic markers

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Cross-talk between <i>Akkermansia muciniphila</i> and intestinal epithelium controls diet-induced obesity

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Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

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Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis

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A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

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Human Genetics Shape the Gut Microbiome

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Metabolite profiles and the risk of developing diabetes

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Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

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Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

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Psychosomatic medicine in Germany: more timely than ever

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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

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Human gut microbes impact host serum metabolome and insulin sensitivity

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The neuroactive potential of the human gut microbiota in quality of life and depression

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The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

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Dietary fiber and prebiotics and the gastrointestinal microbiota

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The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism

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The Distribution and Mechanism of Action of Ghrelin in the CNS Demonstrates a Novel Hypothalamic Circuit Regulating Energy Homeostasis

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Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle

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The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

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Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

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A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

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Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

Chambers, E. S., Viardot, A., Psichas, A., Morrison, D. J., Murphy, K. G., Zac-Varghese, S. E. K., MacDougall, K., Preston, T., Tedford, C., Finlayson, G. S., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307913 · Cited by 1,424 · see citing works

Gut microbial metabolites as multi-kingdom intermediates

Krautkramer, K. A., Fan, J., & Bäckhed, F. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0438-4 · Cited by 1,398 · see citing works

Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

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Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome

Perry, R. J., Peng, L., Barry, N. A., Cline, G. W., Zhang, D., Cardone, R. L., Petersen, K. F., Kibbey, R. G., Goodman, A. L., & Shulman, G. I. (2016) · Nature · doi:10.1038/nature18309 · Cited by 1,299 · see citing works

Pleiotropic Roles of Bile Acids in Metabolism

de Aguiar Vallim, T. Q., Tarling, E. J., & Edwards, P. A. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.03.013 · Cited by 1,209 · see citing works

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Sharon, G., Cruz, N. J., Kang, D.-W., Gandal, M. J., Wang, B., Kim, Y.-M., Zink, E. M., Casey, C. P., Taylor, B. C., Lane, C. J., et al. (2019) · Cell · doi:10.1016/j.cell.2019.05.004 · Cited by 1,182 · see citing works

Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids

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γ-Aminobutyric acid production by culturable bacteria from the human intestine

Barrett, E., Ross, R. P., O'Toole, P. W., Fitzgerald, G. F., & Stanton, C. (2012) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2012.05344.x · Cited by 1,156 · see citing works

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

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The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

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Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

Everard, A., Lazarevic, V., Derrien, M., Girard, M., Muccioli, G. G., Neyrinck, A. M., Possemiers, S., Van Holle, A., François, P., de Vos, W. M., et al. (2011) · Diabetes · doi:10.2337/db11-0227 · Cited by 1,076 · see citing works

Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition

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Mediterranean Diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries

Ghosh, T. S., Rampelli, S., Jeffery, I. B., Santoro, A., Neto, M., Capri, M., Giampieri, E., Jennings, A., Candela, M., Turroni, S., et al. (2020) · Gut · doi:10.1136/gutjnl-2019-319654 · Cited by 991 · see citing works

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

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Involvement of gut microbiota in the development of low-grade inflammation and type 2 diabetes associated with obesity

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Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

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Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women

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Prevalence and correlates of DSM-5-defined eating disorders in a nationally representative sample of U.S. Adults

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Gut hormones and the regulation of energy homeostasis

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Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal

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Gut commensal Parabacteroides goldsteinii plays a predominant role in the anti-obesity effects of polysaccharides isolated from Hirsutella sinensis

Wu, T.-R., Lin, C.-S., Chang, C., Lin, T., Martel, J., Ko, Y., Ojcius, D. M., Lu, C., Young, J. D., & Lai, H. (2018) · Gut · doi:10.1136/gutjnl-2017-315458 · Cited by 757 · see citing works

Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis

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Daily sampling reveals personalized diet-microbiome associations in humans

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Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine

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Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults

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Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor

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Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

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The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level

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Toward a Wiring Diagram Understanding of Appetite Control

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Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

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Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells

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Antibiotic-induced microbiome depletion alters metabolic homeostasis by affecting gut signaling and colonic metabolism

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Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

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Accumulation of succinate controls activation of adipose tissue thermogenesis

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Metabolic and hedonic drives in the neural control of appetite: who is the boss?

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Personalized Mapping of Drug Metabolism by the Human Gut Microbiome

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Ghrelin action in the brain controls adipocyte metabolism

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Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

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Effects of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomized controlled trials

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Microbiota-gut-brain axis: Modulator of host metabolism and appetite

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Microbiota modulate sympathetic neurons via a gut–brain circuit

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Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion

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Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

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Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota

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Microbiota depletion promotes browning of white adipose tissue and reduces obesity

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Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

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Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling

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Citrus polymethoxyflavones attenuate metabolic syndrome by regulating gut microbiome and amino acid metabolism

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Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high‐fat diet‐fed mice

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GABA production and structure of gadB / gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota

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Gut Microbiota Restores Central Neuropeptide Deficits in Germ-Free Mice

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Malnourished Microbes: Host–Microbiome Interactions in Child Undernutrition

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Prevotella and succinate treatments altered gut microbiota, increased laying performance, and suppressed hepatic lipid accumulation in laying hens

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Exploring Gut Microbiota in Systemic Lupus Erythematosus: Insights and Biomarker Discovery Potential

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Nutrition, cognition and chronic kidney disease: A comprehensive review of interactions and interventions

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A database of animal metagenomes

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