The FGF family: biology, pathophysiology and therapy

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

Thalidomide is an inhibitor of angiogenesis.

D'Amato, R. J., Loughnan, M. S., Flynn, E., & Folkman, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.9.4082 · Cited by 2,454

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., & Ornitz, D. M. (1991) · Cell · doi:10.1016/0092-8674(91)90512-w · Cited by 2,440

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23606 · Cited by 2,125

Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

Kirkwood, J. M., Strawderman, M. H., Ernstoff, M. S., Smith, T. J., Borden, E. C., & Blum, R. H. (1996) · Journal of Clinical Oncology · doi:10.1200/jco.1996.14.1.7 · Cited by 2,089

Suppression of Aging in Mice by the Hormone Klotho

Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science · doi:10.1126/science.1112766 · Cited by 1,935

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.001 · Cited by 1,865

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Urakawa, I., Yamazaki, Y., Shimada, T., Iijima, K., Hasegawa, H., Okawa, K., Fujita, T., Fukumoto, S., & Yamashita, T. (2006) · Nature · doi:10.1038/nature05315 · Cited by 1,865

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

Gutiérrez, O. M., Mannstadt, M., Isakova, T., Rauh‐Hain, J. A., Tamez, H. E., Shah, A., Smith, K. T., Lee, H., Thadhani, R., Jüppner, H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706130 · Cited by 1,729

Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.003 · Cited by 1,504

Understanding the Structure-Function Relationship between FGF19 and Its Mitogenic and Metabolic Activities

Wu, X., & Li, Y. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0887-1_13 · Cited by 21

Peptides derived from specific interaction sites of the fibroblast growth factor 2 – FGF receptor complexes induce receptor activation and signaling

Manfé, V., Kochoyan, A., Bock, E., & Berezin, V. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.06718.x · Cited by 21

Potential dual role of KGF/KGFR as a target option in novel therapeutic strategies for the treatment of cancers and mucosal damages

Ceccarelli, S., Romano, F., Angeloni, A., & Marchese, C. (2012) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2012.671813 · Cited by 20

Fibroblast growth factor receptor signaling in metabolic dysfunction-associated fatty liver disease: Pathogenesis and therapeutic targets

Chu, Y., Yang, S., & Chen, X. (2025) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2025.108844 · Cited by 21

Nonsmall Cell Lung Cancer Therapy: Insight into Multitargeted Small-Molecule Growth Factor Receptor Inhibitors

Roy, M., Luo, Y., Ye, M., & Liu, J. (2013) · BioMed Research International · doi:10.1155/2013/964743 · Cited by 20

Hypoxia-Induced Adipose Lipolysis Requires Fibroblast Growth Factor 21

Wu, G., Liu, Y., Feng, W., An, X., Lin, W., & Tang, C. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01279 · Cited by 20

Expedient Synthesis of a Library of Heparan Sulfate‐Like “Head‐to‐Tail” Linked Multimers for Structure and Activity Relationship Studies**

Zhang, J., Liang, L., Yang, W., Ramadan, S., Baryal, K. N., Huo, C., Bernard, J. J., Liu, J., Hsieh‐Wilson, L. C., Zhang, F., et al. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202209730 · Cited by 20

Emerging roles of fibroblast growth factor 21 in critical disease

Fang, Y., Li, Y., Yang, F., Wu, G., & Jiang, X. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1053997 · Cited by 20

Medical treatment for gastro-entero-pancreatic neuroendocrine tumours

Berardi, R., Morgese, F., Torniai, M., Savini, A., Partelli, S., Rinaldi, S., Caramanti, M., Ferrini, C., Falconi, M., & Cascinu, S. (2016) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v8.i4.389 · Cited by 20

Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study

Zhao, Y., Singh, A., Xu, Y., Zong, C., Zhang, F., Boons, G., Liu, J., Linhardt, R. J., Woods, R. J., & Amster, I. J. (2016) · Journal of the American Society for Mass Spectrometry · doi:10.1007/s13361-016-1496-8 · Cited by 20

Physiological and molecular responses to bariatric surgery: markers or mechanisms underlying T2DM resolution?

Hutch, C. R., & Sandoval, D. A. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13194 · Cited by 21

Insight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study

Liang, D., Chen, Q., Guo, Y., Zhang, T., & Guo, W. (2017) · Drug Design Development and Therapy · doi:10.2147/dddt.s129991 · Cited by 20

Non-invasive strategies for stimulating endogenous repair and regenerative mechanisms in the damaged heart

Lewis, F., Kumar, S. D., & Ellison, G. M. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2017.08.016 · Cited by 22

Influence of zinc on glycosaminoglycan neutralisation during coagulation

Sobczak, A. I. S., Pitt, S. J., & Stewart, A. J. (2018) · Metallomics · doi:10.1039/c8mt00159f · Cited by 20

Lipopolysaccharides Improve Mesenchymal Stem Cell-Mediated Cardioprotection by MyD88 and stat3 Signaling in a Mouse Model of Cardiac Ischemia/Reperfusion Injury

Chu, X., Xu, B., Gao, H., Li, B., Liu, Y., Reiter, J. L., & Wang, Y. (2019) · Stem Cells and Development · doi:10.1089/scd.2018.0213 · Cited by 20

Development of a Monomeric Inhibitory RNA Aptamer Specific for FGFR3 that Acts as an Activator When Dimerized

Kamatkar, N. G., Levy, M., & Hébert, J. M. (2019) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.06.020 · Cited by 20

The role of heparan sulfate maturation in cancer: A focus on the 3O-sulfation and the enigmatic 3O-sulfotransferases (HS3STs)

Gulberti, S., Mao, X., Bui, C., & Fournel‐Gigleux, S. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.10.009 · Cited by 22

Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study

Cunningham, D. L., Sarhan, A. R., Creese, A. J., Larkins, K. P. B., Zhao, H., Ferguson, H. R., Brookes, K., Marusiak, A. A., Cooper, H. J., & Heath, J. K. (2020) · Scientific Reports · doi:10.1038/s41598-020-64534-y · Cited by 20

Current understanding and controversies on the clinical implications of fibroblast growth factor 21

Badakhshi, Y., & Jin, T. (2020) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2020.1864278 · Cited by 20

Autophagy-targeting modulation to promote peripheral nerve regeneration

Chen, Y., Deng, H., & Zhang, N. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01948 · Cited by 20

Strategies to Overcome Resistance to Osimertinib in EGFR-Mutated Lung Cancer

Romaniello, D., Morselli, A., & Marrocco, I. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072957 · Cited by 20

Gekko-sulfated Glycopeptide Inhibits Tumor Angiogenesis by Targeting Basic Fibroblast Growth Factor

Zhang, S.-X., Zhu, C., Ba, Y., Chen, D., Zhou, X.-L., Cao, R., Wang, L.-P., Ren, Y., & Wu, X.-Z. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.321521 · Cited by 19

New Directions and Challenges in Targeted Therapies of Advanced Bladder Cancer: The Role of FGFR Inhibitors

Szklener, K., Chmiel, P., Michalski, A., & Mańdziuk, S. (2022) · Cancers · doi:10.3390/cancers14061416 · Cited by 22

Advances in the role and mechanism of fibroblasts in fracture healing

Wang, H., Qi, L., Shema, C., Jiang, K.-Y., Ren, P., Wang, H., & Wang, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1350958 · Cited by 22

The Complexity and Significance of Fibroblast Growth Factor (FGF) Signaling for FGF-Targeted Cancer Therapies

Nguyen, A. L., Facey, C. O. B., & Boman, B. M. (2024) · Cancers · doi:10.3390/cancers17010082 · Cited by 23

Expression of bioactive recombinant human fibroblast growth factor 9 in oil bodies of Arabidopsis thaliana

Yi, S., Yang, J., Huang, J., Guan, L., Du, L., Guo, Y., Zhai, F., Wang, Y., Lu, Z., Wang, L., et al. (2015) · Protein Expression and Purification · doi:10.1016/j.pep.2015.08.006 · Cited by 19

Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system

Murakami, M., & Sakurai, T. (2012) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1190 · Cited by 19

Fibroblast Growth Factor 8b Causes Progressive Stromal and Epithelial Changes in the Epididymis and Degeneration of the Seminiferous Epithelium in the Testis of Transgenic Mice1

Elo, T., Sipilä, P., Valve, E. M., Kujala, P. M., Toppari, J., POUTANEN, M. H., & Härkönen, P. L. (2012) · Biology of Reproduction · doi:10.1095/biolreprod.111.097352 · Cited by 19

Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients

Kilvaer, T. K., Valkov, A., Sørbye, S. W., Smeland, E., Bremnes, R. M., Busund, L., & Dønnem, T. (2011) · Journal of Translational Medicine · doi:10.1186/1479-5876-9-104 · Cited by 19

Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival

Chen, C., Zhang, Y., Loomis, M. M., Upton, M. P., Lohavanichbutr, P., Houck, J. R., Doody, D. R., Méndez, E., Futran, N. D., Schwartz, S. M., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135074 · Cited by 19

Evidence of post-transcriptional readthrough regulation in FGF5 gene of alpaca

Pallotti, S., Pediconi, D., Dharaneedharan, S., Molina, G., Antonini, M., Morelli, M. B., Renieri, C., & Terza, A. L. (2018) · Gene · doi:10.1016/j.gene.2018.01.006 · Cited by 20

The Expression and Prognostic Value of FGF2, FGFR3, and FGFBP1 in Esophageal Squamous Cell Carcinoma

Zhang, W., Zhou, Y., Li, C., Xu, S., Li, M., Liu, W., Ma, Y., & Wang, H. (2020) · Analytical Cellular Pathology · doi:10.1155/2020/2872479 · Cited by 19

Low temperature plasma induces angiogenic growth factor via up-regulating hypoxia–inducible factor 1α in human dermal fibroblasts

Cui, H. S., Joo, S. Y., Lee, D. H., Yu, J. H., Jeong, J. H., Kim, J., & Seo, C. H. (2017) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2017.07.012 · Cited by 19

High-efficiency production of bioactive oleosin-basic fibroblast growth factor in A. thaliana and evaluation of wound healing

Yang, J., Qiang, W., Ren, S., Yi, S., Li, J., Guan, L., Du, L., Guo, Y., Hu, H., Li, H., et al. (2017) · Gene · doi:10.1016/j.gene.2017.09.064 · Cited by 19

The FGFR D3 Domain Determines Receptor Selectivity For Fibroblast Growth Factor 21

Gupte, J., Li, Y., Wu, X., Weiszmann, J., Hecht, R. I., Lemon, B. D., Lindberg, R. A., Wang, Z., & Li, Y. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.03.003 · Cited by 18

Effects of fasting on the expression pattern of FGFs in different skeletal muscle fibre types and sexes in mice

Jia, W., Wang, N., Yin, L., Chen, X., Hou, B., Wang, J., Qiang, G., Chan, C. B., Yang, X., & Du, G. (2020) · Biology of Sex Differences · doi:10.1186/s13293-020-00287-7 · Cited by 18

Mechanisms of Efficacy of the FGFR1–3 Inhibitor AZD4547 in Pediatric Solid Tumor Models

Phanhthilath, N., Hakim, S., Su, C., Liu, A. J., Subramonian, D., Lesperance, J., & Zage, P. E. (2020) · Investigational New Drugs · doi:10.1007/s10637-020-00933-2 · Cited by 18

Therapeutic implications of fibroblast growth factor receptor inhibitors in a combination regimen for solid tumors (Review)

Luo, H., Zhang, T., Cheng, P., Li, D., Ogorodniitchouk, O., Lahmamssi, C., Wang, G., & Lan, M. (2020) · Oncology Letters · doi:10.3892/ol.2020.11858 · Cited by 17

Structure-guided design, generation, and biofunction of PEGylated fibroblast growth factor 2 variants for wound healing

Sun, J., Wu, J., Jin, H. Z., Ying, T., Jin, W., Fan, M., Zhou, J., Chen, H., Jin, L., & Zhou, J. (2020) · Nanoscale · doi:10.1039/d0nr05999d · Cited by 18

Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology

Ahmed, M. B., Mäkinen, V., Mulugeta, A., Shin, J., Boyle, T., Hyppönen, E., & Lee, S. (2022) · Communications Biology · doi:10.1038/s42003-022-03554-y · Cited by 17

Myokines: Novel therapeutic targets for diabetic nephropathy

Yang, M., Luo, S., Yang, J., Chen, W., He, L., Liu, D., Zhao, L., & Wang, X. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1014581 · Cited by 18

Significant Enhancement of Fibroblast Migration, Invasion, and Proliferation by Exosomes Loaded with Human Fibroblast Growth Factor 1.

Hade, M. D., Suire, C. N., & Suo, Z. (2024) · ACS Applied Materials and Interfaces · doi:10.1021/acsami.3c10350 · Cited by 13

The FGF/FGFR/c-Myc axis as a promising therapeutic target in multiple myeloma

Giacomini, A., Taranto, S., Gazzaroli, G., Faletti, J., Capoferri, D., Marcheselli, R., Sciumé, M., Presta, M., Sacco, A., & Roccaro, A. M. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03217-2 · Cited by 19

Fibroblast Growth Factor Receptor 1 as a Target for the Therapy of Renal Cell Carcinoma

Tsimafeyeu, I. V., & Bratslavsky, G. (2015) · Oncology · doi:10.1159/000370118 · Cited by 18

How the concentration of insulin affects the development of preantral follicles in goats

Chaves, R. N., Alves, A. M. C. V., Faustino, L. R., Oliveira, K. P. L., Campello, C. C., Lopes, C. A. P., Báo, S. N., & Figueiredo, J. R. (2011) · Cell and Tissue Research · doi:10.1007/s00441-011-1264-9 · Cited by 18

The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer’s Disease

Martins, I. J. (2016) · Proteomes · doi:10.3390/proteomes4020014 · Cited by 19

Fibroblast growth factor 23, iron and inflammation – are they related in early stages of chronic kidney disease?

Łukaszyk, E., Łukaszyk, M., Koc‐Żórawska, E., Bodzenta­‐Łukaszyk, A., & Małyszko, J. (2016) · Archives of Medical Science · doi:10.5114/aoms.2016.58647 · Cited by 18

Increased Expression of FGF19 Contributes to Tumor Progression and Cell Motility of Human Thyroid Cancer

Zhang, X., Wang, Z., Tian, L., Xie, J., Guijun, Z., & Jiang, F. (2015) · Otolaryngology · doi:10.1177/0194599815609534 · Cited by 18

Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement

Uchida, S., & Shumyatsky, G. P. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.02.016 · Cited by 18

Fibroblast growth factors 19 and 21 in acute liver damage

Shan, Z., Álvarez‐Sola, G., Uriarte, I., Arechederra, M., Fernández‐Barrena, M. G., Berasain, C., Ju, C., & Avila, M. A. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.05.26 · Cited by 19

CYP7A1 expression in hepatocytes is retained with upregulated fibroblast growth factor 19 in pediatric biliary atresia

Hasegawa, Y., Kawai, M., Bessho, K., Yasuda, K., Ueno, T., Satomura, Y., Konishi, A., Kimura, T., Ikeda, K., Tachibana, M., et al. (2018) · Hepatology Research · doi:10.1111/hepr.13245 · Cited by 18

A phase 1 study of oral ASP5878, a selective small-molecule inhibitor of fibroblast growth factor receptors 1–4, as a single dose and multiple doses in patients with solid malignancies

Yamamoto, N., Ryoo, B., Keam, B., Kudo, M., Lin, C., Kunieda, F., Ball, H. A., Moran, D. M., Komatsu, K., Takeda, K., et al. (2019) · Investigational New Drugs · doi:10.1007/s10637-019-00780-w · Cited by 18

Evaluation of VEGF, FGF and PDGF and Serum Levels of Inflammatory Cytokines in Patients with Glioma and Meningioma in Southern Iran

Shamsdin, S. A., Mehrafshan, A., Rakei, S. M., & Mehrabani, D. (2019) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2019.20.10.2883 · Cited by 18

Skeletal muscle–targeted delivery of Fgf6 protects mice from diet-induced obesity and insulin resistance

Xu, B., Liu, C., Zhang, H., Zhang, R., Tang, M., Huang, Y., Li, J., Xu, L., Hu, C., & Jia, W. (2021) · JCI Insight · doi:10.1172/jci.insight.149969 · Cited by 20

circCCT3 Enhances Invasion and Epithelial-Mesenchymal Transition (EMT) of Non-Small-Cell Lung Cancer (NSCLC) via the miR-107/Wnt/FGF7 Axis

Li, J., Lu, R., Yang, K., & Sun, Q. (2022) · Journal of Oncology · doi:10.1155/2022/7020774 · Cited by 18

FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro

Ishino, R., Minami, K., Tanaka, S., Nagai, M., Matsui, K., Hasegawa, N., Roeder, R. G., Asano, S., & Ito, M. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.09.044 · Cited by 18

JNK/ERK/FAK Mediate Promigratory Actions of Basic Fibroblast Growth Factor in Astrocytes via CCL2 and COX2

Lichtenstein, M. P., Madrigal, J. L. M., Pujol, A., & Galea, E. (2011) · Neurosignals · doi:10.1159/000330805 · Cited by 18

Basic fibroblast growth factor suppresses meiosis and promotes mitosis of ovarian germ cells in embryonic chickens

He, B., Lin, J., Li, J., Mi, Y., Zeng, W., & Zhang, C. (2012) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2012.01.012 · Cited by 18

Mast Cell Proteases 6 and 7 Stimulate Angiogenesis by Inducing Endothelial Cells to Release Angiogenic Factors

de Souza, D. A., Borges, A. C., Santana, A. C., Oliver, C., & Jamur, M. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0144081 · Cited by 19

Homology modeling and virtual screening studies of FGF-7 protein—a structure-based approach to design new molecules against tumor angiogenesis

Vadija, R., Mustyala, K. K., Nambigari, N., Dulapalli, R., Dumpati, R. K., Ramatenki, V., Vellanki, S., & Vuruputuri, U. (2016) · Journal of Chemical Biology · doi:10.1007/s12154-016-0152-x · Cited by 18

In silico enhancement of the stability and activity of keratinocyte growth factor

Poorebrahim, M., Sadeghi, S., Ghorbani, R., Asghari, M., Abazari, M. F., Kalhor, H., & Rahimi, H. (2017) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2017.01.009 · Cited by 19

High in situ mRNA levels of IL-22, TFG-β, and ARG-1 in keloid scars

Tiveron, L. R. D. C. C., da Silva, I. R., da Silva, M. V., Peixoto, A. B., Rodrigues, D. B. R., & Rodrigues, V. (2018) · Immunobiology · doi:10.1016/j.imbio.2018.08.010 · Cited by 20

FGF11 influences 3T3‐L1 preadipocyte differentiation by modulating the expression of PPARγ regulators

Lee, K. W., Jeong, J., An, Y. J., Jung-Hyun, L. E. E., & Yim, H. (2019) · FEBS Open Bio · doi:10.1002/2211-5463.12619 · Cited by 18

Isolation of tissue-resident endothelial stem cells and their use in regenerative medicine

Iba, T., Naito, H., Shimizu, S., Rahmawati, F. N., Wakabayashi, T., & Takakura, N. (2019) · Inflammation and Regeneration · doi:10.1186/s41232-019-0098-9 · Cited by 18

The driver of malignancy in KG-1a leukemic cells, FGFR1OP2–FGFR1, encodes an HSP90 addicted oncoprotein

Jin, Y., Zhen, Y., Haugsten, E. M., & Więdłocha, A. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.06.010 · Cited by 18

Cancer-associated adipocytes mediate CD8+T cell dysfunction via FGF21-driven lipolysis

Dalangood, S., Hu, C., Yuan, C., Li, X. O., Qiao, W., Li, H., Zhang, R., Li, L., Peng, L., Yu, X., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116526 · Cited by 18

Across Barriers: Blood–Brain and Gut Barrier Signaling in Psychiatric Disorders

Binder, L. B., Bevilacqua, L. M., Thomassen, F. G. L., Lebel, M., Jensen, B. A. H., & Ménard, C. (2025) · Journal of Neurochemistry · doi:10.1111/jnc.70282 · Cited by 19

Downregulation of microRNA-302b-3p relieves oxygen-glucose deprivation/re-oxygenation induced injury in murine hippocampal neurons through up-regulating Nrf2 signaling by targeting fibroblast growth factor 15/19

Zhang, Z., Wang, N., Zhang, Y., Zhao, J., & Lv, J. (2019) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2019.06.018 · Cited by 17

Intrinsically Fluorescent Oligomeric Cytotoxic Conjugates Toxic for FGFR1-Overproducing Cancers

Porębska, N., Knapik, A., Poźniak, M., Krzyścik, M., Zakrzewska, M., Otlewski, J., & Opaliński, Ł. (2021) · Biomacromolecules · doi:10.1021/acs.biomac.1c01280 · Cited by 16

Using single cell atlas data to reconstruct regulatory networks

Song, Q., Ruffalo, M., & Bar‐Joseph, Z. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad053 · Cited by 23

Biomaterial-Based bFGF Delivery for Nerve Repair

Huang, Q., Liu, B., & Wu, W.-C. (2023) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2023/8003821 · Cited by 19

Receptor tyrosine kinases (RTKs)

Batool, Z., Azfal, A., Liaquat, L., Sadir, S., Nisar, R., Inamullah, A., Ghalib, A. U. F., & Haider, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-443-18677-6.00012-9 · Cited by 17

Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 derived peptide, 44-ERGVVSIKGV-53

Lee, S., Dayem, A. A., Kmiecik, S., Lim, K., Seo, D., Kim, H.-T., Biswas, P. K., Do, M., Kim, D.-H., & Cho, S.-G. (2023) · Journal of Advanced Research · doi:10.1016/j.jare.2023.09.041 · Cited by 18

Quantitative and qualitative differences in the activation of a fibroblast growth factor receptor by different FGF ligands

Krzyścik, M. A., Karl, K., Dudeja, P., Krejčı́, P., & Hristova, K. A. (2024) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2024.07.002 · Cited by 17

Spatial and Temporal Analyses of FGF9 Expression During Early Pregnancy

Šućurović, S., Nikolić, T., Brosens, J. J., & Mulac‐Jeričević, B. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000480004 · Cited by 17

Molecular characterization of the llama FGF 5 gene and identification of putative loss of function mutations

Daverio, M. S., Vidal-Rioja, L., Frank, E., & Rocco, F. D. (2017) · Animal Genetics · doi:10.1111/age.12616 · Cited by 17

Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF

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