The FGF family: biology, pathophysiology and therapy

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837

Thalidomide is an inhibitor of angiogenesis.

D'Amato, R. J., Loughnan, M. S., Flynn, E., & Folkman, J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.9.4082 · Cited by 2,454

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P., & Ornitz, D. M. (1991) · Cell · doi:10.1016/0092-8674(91)90512-w · Cited by 2,440

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23606 · Cited by 2,125

Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

Kirkwood, J. M., Strawderman, M. H., Ernstoff, M. S., Smith, T. J., Borden, E. C., & Blum, R. H. (1996) · Journal of Clinical Oncology · doi:10.1200/jco.1996.14.1.7 · Cited by 2,089

Suppression of Aging in Mice by the Hormone Klotho

Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science · doi:10.1126/science.1112766 · Cited by 1,935

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2005.09.001 · Cited by 1,865

Klotho converts canonical FGF receptor into a specific receptor for FGF23

Urakawa, I., Yamazaki, Y., Shimada, T., Iijima, K., Hasegawa, H., Okawa, K., Fujita, T., Fukumoto, S., & Yamashita, T. (2006) · Nature · doi:10.1038/nature05315 · Cited by 1,865

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

Gutiérrez, O. M., Mannstadt, M., Isakova, T., Rauh‐Hain, J. A., Tamez, H. E., Shah, A., Smith, K. T., Lee, H., Thadhani, R., Jüppner, H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706130 · Cited by 1,729

Endocrine Regulation of the Fasting Response by PPARα-Mediated Induction of Fibroblast Growth Factor 21

Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.05.003 · Cited by 1,504

Environmental regulation of valvulogenesis: implications for tissue engineering

Vis, P. W. R., Kluin, J., Sluijter, J. P. G., van Herwerden, L. A., & Bouten, C. V. C. (2010) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/j.ejcts.2010.05.032 · Cited by 25

Switching off angiogenic signalling: creating channelled constructs for adequate oxygen delivery in tissue engineered constructs

Cheema, U., Alekseeva, T., Neel, E. A. A., & Brown, R. A. (2010) · European Cells and Materials · doi:10.22203/ecm.v020a22 · Cited by 25

Preclinical Pharmacological Evaluation of a Novel Multiple Kinase Inhibitor, ON123300, in Brain Tumor Models

Zhang, X., Lv, H., Zhou, Q. S., Elkholi, R., Chipuk, J. E., Reddy, M. V. R., Reddy, E. P., & Gallo, J. M. (2014) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-13-0847 · Cited by 25

Fibroblast Growth Factor Family in the Progression of Prostate Cancer

Teishima, J., Hayashi, T., Nagamatsu, H., Shoji, K., Shikuma, H., Yamanaka, R., Sekino, Y., Goto, K., Inoue, S., & Matsubara, A. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020183 · Cited by 29

Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development

Chen, L., Li, X., Wang, Y., Song, T., Li, H., Xie, L., Li, L., Chen, X., Ma, L., Chen, Y., et al. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00118 · Cited by 25

Genome-Wide Association Study of Opioid Cessation

Cox, J. W., Sherva, R., Lunetta, K. L., Johnson, E. C., Martin, N. G., Degenhardt, L. J., Arpana Agrawal, A., Nelson, E. C., Kranzler, H. R., Gelernter, J. E., et al. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9010180 · Cited by 28

Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions

Repetto, M., Crimini, E., Giugliano, F., Morganti, S., Belli, C., & Curigliano, G. (2021) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2021.1947246 · Cited by 25

Circulating Thrombospondin-2 and FGF-2 in Patients with Advanced Non-small Cell Lung Cancer: Correlation with Survival

Naumnik, W., Ossolińska, M., Płońska, I., Chyczewska, E., & Nikliński, J. (2014) · Advances in experimental medicine and biology · doi:10.1007/5584_2014_78 · Cited by 25

The roles of FGFR3 and c-MYC in urothelial bladder cancer

Bogale, D. E. (2024) · Discover Oncology · doi:10.1007/s12672-024-01173-z · Cited by 27

Colonic epithelial-derived FGF1 drives intestinal stem cell commitment toward goblet cells to suppress inflammatory bowel disease

Lin, Q., Zhang, S., Zhang, J., Jin, Y., Chen, T., Lin, R., Lv, J., Xu, W., Wu, T., Tian, S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58644-2 · Cited by 26

Regenerative Chemical Biology: Current Challenges and Future Potential

Ao, A. S., Hao, J., & Hong, C. C. (2011) · Chemistry & Biology · doi:10.1016/j.chembiol.2011.03.011 · Cited by 24

Interaction of the receptor FGFRL1 with the negative regulator Spred1

Zhuang, L., Villiger, P. M., & Trüeb, B. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.05.006 · Cited by 24

Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements

Paradiso, B., Zucchini, S., & Simonato, M. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00152 · Cited by 24

The fibroblast growth factor 8 family in the female reproductive tract

Estienne, A., & Price, C. A. (2017) · Reproduction · doi:10.1530/rep-17-0542 · Cited by 25

FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance

Stöhr, O., Tao, R., Miao, J., Copps, K. D., & White, M. F. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108893 · Cited by 24

Peptides Derived from Growth Factors to Treat Alzheimer’s Disease

Gascon, S., Jann, J., Langlois-Blais, C., Plourde, M., Lavoie, C. L., & Faucheux, N. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22116071 · Cited by 24

Endocrine Fibroblast Growth Factors in Relation to Stress Signaling

Shimizu, M., & Sato, R. (2022) · Cells · doi:10.3390/cells11030505 · Cited by 25

Fibroblast Growth Factor Receptor 1-4 Genetic Aberrations as Clinically Relevant Biomarkers in Squamous Cell Lung Cancer

Moes-Sosnowska, J., & Chorostowska-Wynimko, J. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.780650 · Cited by 21

Development of selective FGFR1 degraders using a Rapid synthesis of proteolysis targeting Chimera (Rapid-TAC) platform

Guo, L., Liu, J., Nie, X., Wang, T., Ma, Z., Yin, D., & Tang, W. (2022) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2022.128982 · Cited by 24

Prospective use of amniotic mesenchymal stem cell metabolite products for tissue regeneration

Miatmoko, A., Hariawan, B. S., Cahyani, D. M., Dewangga, S. S., Handoko, K. K., Purwati, P., Sahu, R. K., & Hariyadi, D. M. (2023) · Journal of Biological Engineering · doi:10.1186/s13036-023-00331-1 · Cited by 24

Pioneering therapies for post-infarction angiogenesis: Insight into molecular mechanisms and preclinical studies

Chen, C., Wang, J., Liu, C., Hu, J., & Liu, L. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115306 · Cited by 25

Fibroblast Growth Factor‐9 Activates c‐Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart

Singla, D. K., & Wang, J. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/5810908 · Cited by 24

Gene Therapy to Stimulate Angiogenesis to Treat Diffuse Coronary Artery Disease

Kaminsky, S. M., Rosengart, T. K., Rosenberg, J. B., Chiuchiolo, M. J., de Graaf, B. G. V., Sondhi, D., & Crystal, R. G. (2013) · Human Gene Therapy · doi:10.1089/hum.2013.2516 · Cited by 24

Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer

Inokuchi, M., Fujimori, Y., Otsuki, S., Sato, Y., Nakagawa, M., & Kojima, K. (2015) · Gastroenterology Research and Practice · doi:10.1155/2015/796380 · Cited by 24

TAT-Mediated Acidic Fibroblast Growth Factor Delivery to the Dermis Improves Wound Healing of Deep Skin Tissue in Rat

Zheng, L., Hui, Q., Tang, L., Zheng, L., Jin, Z., Yu, B., Wang, Z., Lin, P., Wei-dan, Y., Li, H., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135291 · Cited by 24

FGFR2 Assessment in Gastric Cancer Using Quantitative Real-Time Polymerase Chain Reaction, Fluorescent In Situ Hybridization, and Immunohistochemistry

Park, Y. S., Na, Y.-S., Ryu, M., Lee, C., Park, H. J., Lee, J., Park, S. R., Ryoo, B., & Kang, Y. (2015) · American Journal of Clinical Pathology · doi:10.1309/ajcpnflsmwwpp8dr · Cited by 24

Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague–Dawley rats fed prenatal low protein and postnatal high-fat diets

Claycombe, K., Vomhof‐DeKrey, E. E., Garcia, R. A. G., Johnson, W. T., Uthus, E. O., & Roemmich, J. N. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.01.008 · Cited by 24

MicroRNA-34a and Impaired FGF19/21 Signaling in Obesity

Fu, T., & Kemper, J. K. (2016) · Vitamins and hormones · doi:10.1016/bs.vh.2016.02.002 · Cited by 24

Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins

Morris, J., Jayanthi, S., Langston, R. G., Daily, A. E., Kight, A. D., McNabb, D. S., Henry, R. L., & Kumar, T. K. S. (2016) · Protein Expression and Purification · doi:10.1016/j.pep.2016.05.013 · Cited by 24

Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity

Bartz, R., Fukuchi, K., Ohtsuka, T., Lange, T., Grüner, K., Watanabe, I., Hayashi, S., Oda, Y., Kawaida, R., Komori, H., et al. (2019) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-18-0048 · Cited by 23

The Suitability of FGF21 and FGF23 as New Biomarkers in Endometrial Cancer Patients

Cymbaluk‐Płoska, A., Gargulińska, P., Chudecka-Glaz, A. M., Kwiatkowski, S., Pius‐Sadowska, E., & Machaliński, B. (2020) · Diagnostics · doi:10.3390/diagnostics10060414 · Cited by 23

FGF signaling in cranial suture development and related diseases

Zhao, X., Erhardt, S., Sung, K., & Wang, J. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1112890 · Cited by 25

Therapeutic utilities of fibroblast growth factor 19

Wu, X., & Li, Y. (2011) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2011.624514 · Cited by 23

Monoclonal Antibody Targeting of Fibroblast Growth Factor Receptor 1c Ameliorates Obesity and Glucose Intolerance via Central Mechanisms

Lelliott, C. J., Ahnmark, A., Admyre, T., Ahlstedt, I., Irving, L. M., Keyes, F., Patterson, L. M., Mumphrey, M. B., Bjursell, M., Gorman, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112109 · Cited by 23

Fibroblast growth factor 19-targeted therapies for the treatment of metabolic disease

Rysz, J., Gluba-Brzózka, A., Mikhailidis, D. P., & Banach, M. (2015) · Expert Opinion on Investigational Drugs · doi:10.1517/13543784.2015.1006357 · Cited by 23

Prognostic roles for fibroblast growth factor receptor family members in malignant peripheral nerve sheath tumor

Zhou, W., Du, X., Song, F., Zheng, H., Chen, K., Zhang, W., & Yang, J. (2016) · Oncotarget · doi:10.18632/oncotarget.8067 · Cited by 23

Proximity Labeling by a Recombinant APEX2–FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4

Zhen, Y., Haugsten, E. M., Singh, S. K., & Wesche, J. (2018) · Biochemistry · doi:10.1021/acs.biochem.8b00120 · Cited by 23

VEGF and FGF signaling during head regeneration in hydra

Turwankar, A., & Ghaskadbi, S. (2019) · Gene · doi:10.1016/j.gene.2019.144047 · Cited by 23

Autocrine FGF1 signaling promotes glucose uptake in adipocytes

Nies, V. J. M., Struik, D., Liu, S., Liu, W., Kruit, J. K., Downes, M., van Zutphen, T., Verkade, H. J., Evans, R. M., & Jonker, J. W. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2122382119 · Cited by 23

Regulation of stem cell fate by HSPGs: implication in hair follicle cycling

Colin-Pierre, C., Baraka, O. E., Danoux, L., Bardey, V., André, V., Ramont, L., & Brézillon, S. (2022) · npj Regenerative Medicine · doi:10.1038/s41536-022-00267-y · Cited by 25

Molecular regulation of satellite cells via intercellular signaling

Yeh, C.-J., Sattler, K. M., & Lepper, C. (2023) · Gene · doi:10.1016/j.gene.2023.147172 · Cited by 26

Approaches Targeting the FGF–FGFR System: a Review of the Recent Patent Literature and Associated Advanced Therapeutic Agents

Herbert, C., Lassalle, G. Y., Alcouffe, C., & Bono, F. (2014) · Pharmaceutical Patent Analyst · doi:10.4155/ppa.14.45 · Cited by 23

The association of depressed angiogenic factors with reduced capillary density in the Rhesus monkey model of myocardial ischemia

Zhang, W., Zhao, X., Xiao, Y., Chen, J., Han, P., Zhang, J., Fu, H., & Kang, Y. J. (2016) · Metallomics · doi:10.1039/c5mt00332f · Cited by 24

Advanced Interfere Treatment of Diabetic Cardiomyopathy Rats by aFGF-Loaded Heparin-Modified Microbubbles and UTMD Technique

Zhang, M., Yu, W., Shen, X.-T., Xiang, Q., Xu, J., Yang, J., Chen, P.-P., Fan, Z.-L., Xiao, J., Zhao, Y., et al. (2016) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-016-6639-4 · Cited by 23

Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis

Park, J.-H., Park, G.-M., & Kim, J. (2015) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2015.19.4.335 · Cited by 23

Structural analysis of synthetic heparan sulfate oligosaccharides with fibroblast growth factors and heparin-binding hemagglutinin

Zulueta, M. M. L., Chyan, C., & Hung, S. (2018) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2018.03.003 · Cited by 24

Up-Regulated FGFR1 Expression as a Mediator of Intrinsic TKI Resistance in EGFR-Mutated NSCLC

Gammelgaard, K. R., Vad‐Nielsen, J., Clement, M. S., Weiss, S., Daugaard, T. F., Dagnæs‐Hansen, F., Meldgaard, P., Sørensen, B. S., & Nielsen, A. L. (2018) · Translational Oncology · doi:10.1016/j.tranon.2018.11.017 · Cited by 23

Collagen sponge scaffolds containing growth factors for the functional regeneration of tracheal epithelium

Nakamura, R., Katsuno, T., Kitamura, M., Yamashita, M., Tsuji, T., Suzuki, R., Kishimoto, Y., Suehiro, A., Tateya, I., Nakamura, T., et al. (2019) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2835 · Cited by 23

Fibroblast growth factor signaling in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Paving the way to hepatocellular carcinoma

Ocker, M. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i3.279 · Cited by 23

Serum Endocrine Fibroblast Growth Factors as Potential Biomarkers for Chronic Kidney Disease and Various Metabolic Dysfunctions in Aged Patients

Yamamoto, S., Koyama, D., Igarashi, R., Maki, T., Mizuno, H., Furukawa, Y., & Kuro‐o, M. (2020) · Internal Medicine · doi:10.2169/internalmedicine.3597-19 · Cited by 23

Long-Term Toxicity Study of Topical Administration of a Highly-Stable rh-aFGF Carbomer 940 Hydrogel in a Rabbit Skin Wound Model

Zhang, L., Huang, T., Bi, J., Zheng, Y., Lü, C., Hui, Q., Wang, X., & Lin, X. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00058 · Cited by 23

Sustained release and protein stabilization reduce the growth factor dosage required for human pluripotent stem cell expansion

Khalil, A. S., Xie, A. W., Johnson, H. J., & Murphy, W. L. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2020.120007 · Cited by 23

Is Cerebrospinal Fluid Fibroblast Growth Factor 19 (FGF19) a mood regulator?

Liu, Y., Yu, D., Wang, X., Tan, X., Luo, X., Fan, H., Kang, Y., Xiao, J., Li, X., & Wang, F. (2017) · Neuropsychiatry · doi:10.4172/neuropsychiatry.1000187 · Cited by 22

Roles of FGFR in oral carcinogenesis

Xie, X., Wang, Z., Chen, F., Yao Zong, Y. U. A. N., Wang, J., Liu, R. R., & Chen, Q. (2016) · Cell Proliferation · doi:10.1111/cpr.12260 · Cited by 23

miR‑210 promotes human osteosarcoma cell migration and invasion by targeting FGFRL1

Liu, X., Zhang, C., Wang, C., Sun, J., Wang, D., Zhao, Y., & Xu, X. (2018) · Oncology Letters · doi:10.3892/ol.2018.8939 · Cited by 22

FGF23, a novel muscle biomarker detected in the early stages of ALS

Si, Y., Kazamel, M., Benatar, M. G., Wuu, J., Kwon, Y., Kwan, T., Jiang, N., Kentrup, D., Faul, C., Alesce, L., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-91496-6 · Cited by 22

Fgf15 Neurons of the Dorsomedial Hypothalamus Control Glucagon Secretion and Hepatic Gluconeogenesis

Picard, A., Metref, S., Tarussio, D., Dolci, W., Berney, X. P., Croizier, S., Labouèbe, G., & Thorens, B. (2021) · Diabetes · doi:10.2337/db20-1121 · Cited by 22

Stabilisation of Recombinant Human Basic Fibroblast Growth Factor (FGF-2) against Stressors Encountered in Medicinal Product Processing and Evaluation

Benington, L. R., Rajan, G. P., Locher, C., & Lim, L. Y. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13111762 · Cited by 22

Roles of Therapeutic Bioactive Compounds in Hepatocellular Carcinoma

Jain, D., Murti, Y., Khan, W. U., Hossain, R., Hossain, M. N., Agrawal, K. K., Ashraf, R. A., Islam, M. T., Janmeda, P., Taheri, Y., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/9068850 · Cited by 24

Fibroblast growth factor 21: A “rheostat” for metabolic regulation?

She, Q.-Y., Bao, J., Wang, H.-Z., Liang, H., Huang, W., Wu, J., Zhong, Y.-W., Ling, H., Li, A., & Qin, S.-L. (2022) · Metabolism · doi:10.1016/j.metabol.2022.155166 · Cited by 22

Deficiency of zebrafish fgf20a results in aberrant skull remodeling that mimics both human cranial disease and evolutionarily important fish skull morphologies

Cooper, W. J., Wirgau, R. M., Sweet, E. M., & Albertson, R. C. (2013) · Evolution & Development · doi:10.1111/ede.12052 · Cited by 22

Heart-specific expression of FGF-16 and a potential role in postnatal cardioprotection

Wang, J., Sontag, D., & Cattini, P. A. (2014) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2014.07.007 · Cited by 22

Anti-angiogenic therapy in pediatric brain tumors: An effective strategy?

Sie, M., den Dunnen, W. F. A., Hoving, E. W., & de Bont, E. S. J. M. (2013) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2013.09.005 · Cited by 23

Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma

Kamath, A. V., Lu, D., Gupta, P., Jin, D., Xin, Y., Brady, A., Stéphan, J.-P., Li, H., Tien, J., Qing, J., et al. (2011) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-011-1807-5 · Cited by 22

Computer-Aided Discovery of New Fgfr-1 Inhibitors Followed by In Vitro Validation

Alabed, S. J., Khanfar, M. A., & Taha, M. O. (2016) · Future Medicinal Chemistry · doi:10.4155/fmc-2016-0056 · Cited by 22

Purification of recombinant human fibroblast growth factor 13 in E. coli and its molecular mechanism of mitogenesis

Lin, H., Lu, P., Zhou, M., Wu, F., Weng, L., Meng, K., Yang, D., Li, S., Jiang, C., & Tian, H. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-09973-y · Cited by 21

The Enterokine Fibroblast Growth Factor 15/19 in Bile Acid Metabolism

Cariello, M., Piglionica, M., Gadaleta, R. M., & Moschetta, A. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_235 · Cited by 22

Myocardial protection by heparin-based coacervate of FGF10

Wang, Z., Huang, Y., He, Y., Khor, S., Zhong, X., Xiao, J., Ye, Q., & Li, X. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.12.002 · Cited by 22

Promising Molecular Targets for the Targeted Therapy of Biliary Tract Cancers: An Overview

Yang, W., & Sun, Y. (2021) · OncoTargets and Therapy · doi:10.2147/ott.s297643 · Cited by 22

Cardiac Differentiation of Mesenchymal Stem Cells: Impact of Biological and Chemical Inducers

Ramesh, S., Govarthanan, K., Ostrovidov, S., Zhang, H., Hu, Q., Camci‐Unal, G., Verma, R. S., & Ramalingam, M. (2021) · Stem Cell Reviews and Reports · doi:10.1007/s12015-021-10165-3 · Cited by 23

Salivary Gland Regeneration

Carpenter, G. H., & Cotroneo, E. (2010) · Frontiers of oral physiology/Frontiers of oral biology · doi:10.1159/000313710 · Cited by 22

Coordination of Cell Differentiation and Migration in Mathematical Models of Caudal Embryonic Axis Extension

Harrison, N., del Corral, R. D., & Vasiev, B. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022700 · Cited by 22

Deletion of Soluble Epoxide Hydrolase Attenuates Cardiac Hypertrophy via Down-Regulation of Cardiac Fibroblasts–Derived Fibroblast Growth Factor-2

Zhang, H., Wang, T., Zhang, K., Liu, Y., Huang, F., Zhu, X., Liu, Y., Wang, M.-H., Tang, W., Wang, J., et al. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000226 · Cited by 22

Sphingosine-1-phosphate induces VEGF-C expression through a MMP-2/FGF-1/FGFR-1-dependent pathway in endothelial cells in vitro

Chang, C.-H., Huang, Y., Shyu, M., Chen, S., Lin, C., Ju, T.-K., Lu, J., & Lee, H. (2013) · Acta Pharmacologica Sinica · doi:10.1038/aps.2012.186 · Cited by 22

Acquired nintedanib resistance in FGFR1-driven small cell lung cancer: role of endothelin-A receptor-activated ABCB1 expression

Englinger, B., Lötsch, D., Pirker, C., Mohr, T. T., van Schoonhoven, S., Boidol, B., Lardeau, C.-H., Spitzwieser, M., Szabó, P. T., Heffeter, P., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.10324 · Cited by 22

ROCK/actin/MRTF signaling promotes the fibrogenic phenotype of fibroblast-like synoviocytes derived from the temporomandibular joint

Yokota, S., Chosa, N., Kyakumoto, S., Kimura, H., Ibi, M., Kamo, M., Satoh, K., & Ishisaki, A. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.2896 · Cited by 22

3D spheroid culture synchronizes heterogeneous MSCs into an immunomodulatory phenotype with enhanced anti-inflammatory effects

Lu, R., Zheng, K., Zhou, Y., Wang, W., Zhang, Y., Chen, Y., Mo, M., Li, X., Dong, Y., Xie, J., et al. (2024) · iScience · doi:10.1016/j.isci.2024.110811 · Cited by 21

Fibroblast growth factor–transforming growth factor beta dialogues, endothelial cell to mesenchymal transition, and atherosclerosis

Chen, P., & Simons, M. (2018) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000542 · Cited by 21

Protective effects of FGF10 on neurovascular unit in a rat model of neonatal hypoxic-ischemic brain injury

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