Myeloid-derived-suppressor cells as regulators of the immune system

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1. Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy
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2. Gemcitabine nanoparticles promote antitumor immunity against melanoma
   Zhang, Yuan, Bush, Xin, Yan, Bingfang, Chen, Justin A. · 2019 · Biomaterials
3. Hypoxia-induced PD-L1/PD-1 crosstalk impairs T-cell function in sleep apnoea
   Cubillos-Zapata, Carolina, Avendaño-Ortiz, Jose, Hernandez-Jimenez, Enrique, Toledano, Victor, Casas-Martin, Jose, Varela-Serrano, Anibal, Torres, Marta, Almendros, Isaac, Casitas, Raquel, Fernández-Navarro, Isabel et al. · 2017 · European Respiratory Journal
4. B cells and autoantibodies: Complex roles in CNS injury
   Ankeny, Daniel P., Popovich, Phillip G. · 2010 · Trends in Immunology
5. Immunosuppressive MDSCs induced by TLR signaling during infection and role in resolution of inflammation
   Ray, Anuradha, Chakraborty, Krishnendu, Ray, Prabir · 2013 · Frontiers in Cellular and Infection Microbiology
6. Determinants and functions of CAFs secretome during cancer progression and therapy
   Linares, Jenniffer, Marín-Jiménez, Juan A., Badia-Ramentol, Jordi, Calon, Alexandre · 2021 · Frontiers in Cell and Developmental Biology
7. Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer
   McLoed, Allyson G., Sherrill, Taylor P., Cheng, Dong-Sheng, Han, Wei, Saxon, Jamie A., Gleaves, Linda A., Wu, Pingsheng, Polosukhin, Vasiliy V., Karin, Michael, Yull, Fiona E. et al. · 2016 · Cell Reports
8. Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLC
   Tang, Kwan Ho, Li, Shuai, Khodadadi-Jamayran, Alireza, Jen, Jayu, Han, Han, Guidry, Kayla, Chen, Ting, Hao, Yuan, Fedele, Carmine, Zebala, John A. et al. · 2022 · Cancer Discovery
9. Tumor-associated macrophage polarization in the inflammatory tumor microenvironment
   Zou, Zijuan, Lin, Hongfen, Li, Mengsen, Lin, Bo · 2023 · Frontiers in Oncology
10. Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment
    Vickman, Renee E., Broman, Meaghan M., Lanman, Nadia A., Franco, Omar E., Sudyanti, Putu Ayu G., Ni, Yang, Ji, Yuan, Helfand, Brian T., Petkewicz, Jacqueline, Paterakos, Michael C. et al. · 2020 · The Prostate
11. The importance of immune checkpoints in immune monitoring: A future paradigm shift in the treatment of cancer
    Alemohammad, Hajar, Najafzadeh, Basira, Asadzadeh, Zahra, Baghbanzadeh, Amir, Ghorbaninezhad, Farid, Najafzadeh, Arezoo, Safarpour, Hossein, Bernardini, Renato, Brunetti, Oronzo, Sonnessa, Margherita et al. · 2022 · Biomedicine & Pharmacotherapy
12. Myeloid cell dysfunction and the pathogenesis of the diabetic chronic wound
    Wicks, Kate, Torbica, Tanja, Mace, Kimberly A. · 2014 · Seminars in Immunology
13. Aurora A inhibition eliminates myeloid cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in breast cancer
    Yin, Tingting, Zhao, Zhi-Bin, Guo, Jing, Wang, Tianchen, Yang, Jing-Bo, Wang, Chao, Long, Jie, Ma, Shisong, Huang, Qiang, Zhang, Kaiguang et al. · 2019 · Cancer Research
14. Harnessing and Enhancing Macrophage Phagocytosis for Cancer Therapy
    Chen, Siqi, Lai, Seigmund W. T., Brown, Christine E., Feng, Mingye · 2021 · Frontiers in Immunology
15. Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
    Salminen, Antero, Kauppinen, Anu, Kaarniranta, Kai · 2018 · Biogerontology
16. Activated hepatic stellate cells promote liver cancer by induction of myeloid-derived suppressor cells through cyclooxygenase-2
    Xu, Yaping, Zhao, Wenxiu, Xu, Jianfeng, Li, Jie, Hong, Zaifa, Yin, Zhenyu, Wang, Xiaomin · 2016 · Oncotarget
17. STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers
    Moreira, Dayson, Adamus, Tomasz, Zhao, Xingli, Su, Yu-Lin, Zhang, Zhuoran, White, Seok Voon, Swiderski, Piotr, Lu, Xin, DePinho, Ronald A., Pal, Sumanta K. et al. · 2018 · Clinical Cancer Research
18. Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties
    Novitskiy, Sergey V, Pickup, Michael W, Chytil, Anna, Polosukhina, Dina, Owens, Philip, Moses, Harold L · 2012 · Journal of Leukocyte Biology
19. Ibrutinib treatment inhibits breast cancer progression and metastasis by inducing conversion of myeloid-derived suppressor cells to dendritic cells
    Varikuti, Sanjay, Singh, Bhawana, Volpedo, Greta, Ahirwar, Dinesh K., Jha, Bijay K., Saljoughian, Noushin, Viana, Agostinho G., Verma, Chaitenya, Hamza, Omar, Halsey, Gregory et al. · 2020 · British Journal of Cancer
20. Role of Tumor Pericytes in the Recruitment of Myeloid-Derived Suppressor Cells
    Hong, JongWook, Tobin, Nicholas P., Rundqvist, Helene, Li, Tian, Lavergne, Marion, García-Ibáñez, Yaiza, Qin, Hanyu, Paulsson, Janna, Zeitelhofer, Manuel, Adzemovic, Milena Z. et al. · 2015 · Journal of the National Cancer Institute
21. Gr1intCD11b+ Myeloid-Derived Suppressor Cells in Mycobacterium tuberculosis Infection
    Obregón-Henao, Andrés, Henao-Tamayo, Marcela, Orme, Ian M., Ordway, Diane J. · 2013 · PLoS ONE
22. Interactions between cancer stem cells, immune system and some environmental components: Friends or foes?
    Vahidian, Fatemeh, Duijf, Pascal H.G., Safarzadeh, Elham, Derakhshani, Afshin, Baghbanzadeh, Amir, Baradaran, Behzad · 2019 · Immunology Letters
23. Location, location, location: functional and phenotypic heterogeneity between tumor-infiltrating and non-infiltrating myeloid-derived suppressor cells
    Maenhout, Sarah K, Thielemans, Kris, Aerts, Joeri L · 2014 · OncoImmunology
24. Circulating myeloid-derived suppressor cells increase in patients undergoing neo-adjuvant chemotherapy for breast cancer
    Wesolowski, Robert, Duggan, Megan C., Stiff, Andrew, Markowitz, Joseph, Trikha, Prashant, Levine, Kala M., Schoenfield, Lynn, Abdel-Rasoul, Mahmoud, Layman, Rachel, Ramaswamy, Bhuvaneswari et al. · 2017 · Cancer Immunology, Immunotherapy
25. p16Ink4a and p21Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis
    Okuma, Atsushi, Hanyu, Aki, Watanabe, Sugiko, Hara, Eiji · 2017 · Nature Communications
26. Drug-induced allergic hepatitis develops in mice when myeloid-derived suppressor cells are depleted prior to halothane treatment
    Chakraborty, Mala, Fullerton, Aaron M., Semple, Kenrick, Chea, Lynette S., Proctor, William R., Bourdi, Mohammed, Kleiner, David E., Zeng, Xiangbin, Ryan, Pauline M., Dagur, Pradeep K. et al. · 2015 · Hepatology
27. TGFβ and cancer metastasis: an inflammation link
    Yang, Li · 2010 · Cancer and Metastasis Reviews
28. Novel therapeutic approach to improve hematopoiesis in low risk MDS by targeting MDSCs with the Fc-engineered CD33 antibody BI 836858
    Eksioglu, E A, Chen, X, Heider, K-H, Rueter, B, McGraw, K L, Basiorka, A A, Wei, M, Burnette, A, Cheng, P, Lancet, J et al. · 2017 · Leukemia
29. Drug resistance in multiple myeloma: Soldiers and weapons in the bone marrow niche
    Solimando, Antonio Giovanni, Malerba, Eleonora, Leone, Patrizia, Prete, Marcella, Terragna, Carolina, Cavo, Michele, Racanelli, Vito · 2022 · Frontiers in Oncology
30. Clinical perspectives on the age-related increase of immunosuppressive activity
    Salminen, Antero · 2022 · Journal of Molecular Medicine
31. Myeloid-derived suppressor cells in major depression patients suppress T-cell responses through the production of reactive oxygen species
    Wei, Jianyang, Zhang, Ming, Zhou, Jie · 2015 · Psychiatry Research
32. Hypoxia-inducible factors as key regulators of tumor inflammation
    Mamlouk, Soulafa, Wielockx, Ben · 2013 · International Journal of Cancer
33. Prognostic Significance of the Lymphocyte-to-Monocyte Ratio in Patients with Malignant Pleural Mesothelioma
    Yamagishi, Tomoko, Fujimoto, Nobukazu, Nishi, Hideyuki, Miyamoto, Yosuke, Hara, Naofumi, Asano, Michiko, Fuchimoto, Yasuko, Wada, Sae, Kitamura, Kenichi, Ozaki, Shinji et al. · 2015 · Lung Cancer
34. Necrosis: C-Type Lectins Sense Cell Death
    Cambi, Alessandra, Figdor, Carl · 2009 · Current Biology
35. GB1275, a first-in-class CD11b modulator: rationale for immunotherapeutic combinations in solid tumors
    DeNardo, David G, Galkin, Anna, Dupont, Jakob, Zhou, Lei, Bendell, Johanna · 2021 · Journal for ImmunoTherapy of Cancer
36. Minding the body: Psychotherapy and cancer survival
    Spiegel, David · 2014 · British Journal of Health Psychology
37. Neutrophilic Granulocytes Modulate Invariant NKT Cell Function in Mice and Humans
    Wingender, Gerhard, Hiss, Marcus, Engel, Isaac, Peukert, Konrad, Ley, Klaus, Haller, Hermann, Kronenberg, Mitchell, von Vietinghoff, Sibylle · 2012 · The Journal of Immunology
38. Chronic Psychological Stress Induces the Accumulation of Myeloid-Derived Suppressor Cells in Mice
    Jin, Jianfeng, Wang, Xiaoqian, Wang, Qingyang, Guo, Xiangrui, Cao, Junxia, Zhang, Xueying, Zhu, Ting, Zhang, Dalin, Wang, Wendie, Wang, Jing et al. · 2013 · PLoS ONE
39. Long term impact of CTLA4 blockade immunotherapy on regulatory and effector immune responses in patients with melanoma
    Retseck, Janet, Nasr, Alexis, Lin, Yan, Lin, Huang, Mendiratta, Prateek, Butterfield, Lisa H., Tarhini, Ahmad A. · 2018 · Journal of Translational Medicine
40. TGF-beta: a master switch in tumor immunity
    Gigante, Margherita, Gesualdo, Loreto, Ranieri, Elena · 2012 · Current Pharmaceutical Design
41. Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
    Park, Jeong A, Espinosa-Cotton, Madelyn, Guo, Hong-fen, Monette, Sebastien, Cheung, Nai-Kong V · 2023 · Journal for ImmunoTherapy of Cancer
42. Leveraging microenvironmental synthetic lethalities to treat cancer
    Metcalf, Kevin J., Alazzeh, Alaa, Werb, Zena, Weaver, Valerie M. · 2021 · Journal of Clinical Investigation
43. Perspectives on Hypoxia Signaling in Tumor Stroma
    Zhang, Yuqing, Coleman, Morgan, Brekken, Rolf A. · 2021 · Cancers
44. Single‐cell RNAseq provides insight into altered immune cell populations in human fracture nonunions
    Avin, Keith G., Dominguez, James M., Chen, Neal X., Hato, Takashi, Myslinski, Jered J., Gao, Hongyu, Liu, Yunlong, McKinley, Todd O., Brown, Krista M., Moe, Sharon M. et al. · 2023 · Journal of Orthopaedic Research
45. S100A8 Production in CXCR2-Expressing CD11b+Gr-1high Cells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet
    Mukai, Kaori, Miyagi, Takuya, Nishio, Kumiko, Yokoyama, Yoshinobu, Yoshioka, Teppei, Saito, Yoshinobu, Tanaka, Satoshi, Shigekawa, Minoru, Nawa, Takatoshi, Hikita, Hayato et al. · 2016 · The Journal of Immunology
46. Immunotherapy Resistance in Glioblastoma
    Wang, Elaina J., Chen, Jia-Shu, Jain, Saket, Morshed, Ramin A., Haddad, Alexander F., Gill, Sabraj, Beniwal, Angad S., Aghi, Manish K. · 2021 · Frontiers in Genetics
47. TREM2: Keeping Pace With Immune Checkpoint Inhibitors in Cancer Immunotherapy
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48. High Levels of BMP2 Promote Liver Cancer Growth via the Activation of Myeloid-Derived Suppressor Cells
    Wu, Gui, Huang, Fei, Chen, Yaoqing, Zhuang, Yuehong, Huang, Yunpeng, Xie, Yun · 2020 · Frontiers in Oncology
49. Immunologic Correlates in the Course of Treatment With Immunomodulating Antibodies
    Weide, Benjamin, Di Giacomo, Anna Maria, Fonsatti, Ester, Zitvogel, Laurence · 2015 · Seminars in Oncology
50. Redox Remodeling by Dendritic Cells Protects Antigen-Specific T Cells against Oxidative Stress
    Martner, Anna, Aurelius, Johan, Rydström, Anna, Hellstrand, Kristoffer, Thorén, Fredrik B · 2011 · The Journal of Immunology
51. The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis
    Grasso, Francesca, Di Meo, Serena, De Luca, Gabriele, Pasquini, Luca, Rossi, Stefania, Boirivant, Monica, Biffoni, Mauro, Bignami, Margherita, Di Carlo, Emma · 2015 · Oncotarget
52. CD8 T Cell–Independent Antitumor Response and Its Potential for Treatment of Malignant Gliomas
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