The history of toll-like receptors - redefining innate immunity

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

A Toll-like receptor recognizes bacterial DNA

Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. (2000) · Nature · doi:10.1038/35047123 · Cited by 6,491

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature · doi:10.1038/35099560 · Cited by 6,129

Function and Activation of NF-kappaB in the Immune System

Baeuerle, P. A., & Henkel, T. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.001041 · Cited by 4,745

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Lemaître, B., Nicolas, E., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80172-5 · Cited by 4,224

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

Wright, S. D., Ramos, R., Tobias, P. S., Ulevitch, R. J., & Mathison, J. C. (1990) · Science · doi:10.1126/science.1698311 · Cited by 3,986

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., & Bauer, S. (2004) · Science · doi:10.1126/science.1093620 · Cited by 3,947

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Hayashi, F., Smith, K. D., Ozinsky, A., Hawn, T. R., Yi, E. C., Goodlett, D. R., Eng, J. K., Akira, S., Underhill, D. M., & Aderem, A. A. (2001) · Nature · doi:10.1038/35074106 · Cited by 3,605

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444

Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats

Tørresen, O. K., Brieuc, M. S. O., Solbakken, M. H., Sørhus, E., Nederbragt, A. J., Jakobsen, K. S., Meier, S., Edvardsen, R. B., & Jentoft, S. (2018) · BMC Genomics · doi:10.1186/s12864-018-4616-y · Cited by 42

Understanding the role of Toll-like receptors in lung cancer immunity and immunotherapy

Hoden, B., DeRubeis, D., Martinez-Moczygemba, M., Ramos, K. S., & Zhang, D. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1033483 · Cited by 40

Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8

Meng, J., Liu, X., Zhang, P., Li, D., Xu, S., Zhou, Q., Guo, M., Huai, W., Chen, X., Wang, Q., et al. (2016) · Journal of Autoimmunity · doi:10.1016/j.jaut.2016.05.012 · Cited by 42

CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling

Narayanaswamy, P. B., Tkachuk, S., Haller, H. G., Dumler, I., & Kiyan, Y. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.291 · Cited by 40

The role of human phospholipid scramblases in apoptosis: An overview

Sivagnanam, U., Palanirajan, S. K., & Gummadi, S. N. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2017.08.008 · Cited by 40

CpG ODN1826 as a Promising Mucin1-Maltose-Binding Protein Vaccine Adjuvant Induced DC Maturation and Enhanced Antitumor Immunity

Jie, J., Zhang, Y., Zhou, H., Zhai, X., Zhang, N., Yuan, H., Ni, W., & Tai, G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19030920 · Cited by 40

HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways

Alam, M. M., Yang, D., Trivett, A. L., Meyer, T. J., & Oppenheim, J. J. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02982 · Cited by 40

β-Glucan-Induced Trained Immunity in Dogs

Paris, S., Chapat, L., Pasin, M., Lambiel, M., Sharrock, T. E., Shukla, R., Sigoillot-Claude, C., Bonnet‐Garin, J., Poulet, H., Freyburger, L., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.566893 · Cited by 42

Evaluation of immune status in testis and macrophage polarization associated with testicular damage in patients with nonobstructive azoospermia

Zheng, W., Zhang, S., Jiang, S., Huang, Z., Chen, X., Guo, H., Li, M., & Zheng, S. (2021) · American Journal of Reproductive Immunology · doi:10.1111/aji.13481 · Cited by 42

Purification, identification and functional characterization of an immunomodulatory protein from Pleurotus eryngii

Hu, Q., Du, H., Ma, G., Pei, F., Ma, N., Yuan, B., Nakata, P. A., & Yang, W. (2018) · Food & Function · doi:10.1039/c8fo00604k · Cited by 40

Mechanisms of Stress‐Induced Visceral Pain: Implications in Irritable Bowel Syndrome

Meerveld, B. G., Moloney, R. D., Johnson, A. C., & Vicario, M. (2016) · Journal of Neuroendocrinology · doi:10.1111/jne.12361 · Cited by 39

Canine susceptibility to visceral leishmaniasis: A systematic review upon genetic aspects, considering breed factors and immunological concepts

de Vasconcelos, T. C. B., Furtado, M. C., Belo, V. S., Morgado, F. N., & Figueiredo, F. B. (2017) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2017.10.005 · Cited by 39

Toll‐like receptors 7 and 9 in myasthenia gravis thymus: amplifiers of autoimmunity?

Cavalcante, P., Barzago, C., Baggi, F., Antozzi, C. G., Maggi, L., Mantegazza, R., & Bernasconi, P. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13534 · Cited by 40

Thymol alleviates lipopolysaccharide-stimulated inflammatory response via downregulation of RhoA-mediated NF-κB signalling pathway in human peritoneal mesothelial cells

Wang, Q., Cheng, F., Xu, Y., Zhang, J., Qi, J., Liu, X., & Wang, R. (2018) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2018.06.003 · Cited by 39

Nucleic acids presenting polymer nanomaterials as vaccine adjuvants

Comberlato, A., Paloja, K., & Bastings, M. M. C. (2019) · Journal of Materials Chemistry B · doi:10.1039/c9tb01222b · Cited by 39

Macrophage activation as an archetype of mitochondrial repurposing

Jones, A. E., & Divakaruni, A. S. (2020) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2019.100838 · Cited by 41

STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis

Dawson, R., Deswaerte, V., West, A. C., Tang, K., West, A. J., Balic, J. J., Gearing, L. J., Saad, M. I., Yu, L., Wu, Y., et al. (2021) · Gut · doi:10.1136/gutjnl-2020-323916 · Cited by 40

Type I IFN–Inducible Downregulation of MicroRNA-27a Feedback Inhibits Antiviral Innate Response by Upregulating Siglec1/TRIM27

Zheng, Q., Hou, J., Zhou, Y., Yang, Y., & Cao, X. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1502134 · Cited by 39

TLR4, TLR7/8 agonist-induced miR-146a promotes macrophage tolerance to MyD88-dependent TLR agonists

Nahid, M. A., Benso, L., Shin, J. D., Mehmet, H., Hicks, A., & Ramadas, R. A. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.2a0515-197r · Cited by 39

CYP2J2 – regulation, function and polymorphism

Murray, M. T. (2016) · Drug Metabolism Reviews · doi:10.1080/03602532.2016.1188938 · Cited by 40

NF-κB Regulation by Gut Microbiota Decides Homeostasis or Disease Outcome During Ageing

Zhang, S., Paul, S., & Kundu, P. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.874940 · Cited by 40

Nanocodelivery of an NIR photothermal agent and an acid-responsive TLR7 agonist prodrug to enhance cancer photothermal immunotherapy and the abscopal effect

Chen, B., Huang, R., Zeng, W., Wang, W., & Min, Y. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122434 · Cited by 38

Real-time imaging and genetic dissection of host-microbe interactions in zebrafish

Meijer, A. H., van der Vaart, M., & Spaink, H. P. (2013) · Cellular Microbiology · doi:10.1111/cmi.12236 · Cited by 41

A20 expression in dendritic cells protects mice from LPS‐induced mortality

Xuân, N. T., Wang, X., Nishanth, G., Waisman, A., Borucki, K., Isermann, B., Naumann, M., Deckert, M., & Schlüter, D. (2014) · European Journal of Immunology · doi:10.1002/eji.201444795 · Cited by 38

Pleurotus ferulae water extract enhances the maturation and function of murine bone marrow-derived dendritic cells through TLR4 signaling pathway

Li, J., Wang, X., Wang, W., Luo, J., Aipire, A., Li, J., & Fuchun, Z. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.02.063 · Cited by 38

In Ovo Delivery of CpG DNA Reduces Avian Infectious Laryngotracheitis Virus Induced Mortality and Morbidity

Thapa, S., Cader, M. A., Murugananthan, K., Nagy, É., Sharif, S., Czub, M., & Abdul-Careem, M. F. (2015) · Viruses · doi:10.3390/v7041832 · Cited by 38

PcToll3 was involved in anti- Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii

Lan, J.-F., Wei, S., Wang, Y., Dai, Y., Tu, J., Zhao, L., Li, X.-C., Qin, Q., Chen, N., & Lin, L. (2016) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2016.08.021 · Cited by 38

TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism

New, M. I., Sheikh, S., Bekheet, M., Olzscha, H., Thézénas, M., Care, M. A., Fotheringham, S. A., Tooze, R. M., Kessler, B. M., & Thangue, N. B. L. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-0504 · Cited by 40

Serotonin disturbs colon epithelial tolerance of commensal E. coli by increasing NOX2-derived superoxide

Banskota, S., Regmi, S. C., Gautam, J., Gurung, P., Lee, Y., Ku, S., Lee, J., Lee, J., Chang, H. W., Park, S. J., et al. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.02.034 · Cited by 38

Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta1–42-Induced Toxicity in SH-SY5Y Cells

Amiri, M., Braidy, N., & Aminzadeh, M. (2018) · Neurotoxicity Research · doi:10.1007/s12640-018-9914-2 · Cited by 38

The immune evasion strategies of fish viruses

Guo, C.-J., He, J., & He, J. G. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.12.013 · Cited by 38

Toll‐like receptors: A pathway alluding to cancer control

Ayala‐Cuellar, A. P., Cho, J., & Choi, K. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28879 · Cited by 38

Tumor‐Selective Activation of Toll‐Like Receptor 7/8 Agonist Nano‐Immunomodulator Generates Safe Anti‐Tumor Immune Responses upon Systemic Administration

Hao, Y., Li, H., Ge, X., Liu, Y., Li, X., Liu, Y., Chen, H., Zhang, S., Zou, J., Huang, L., et al. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202214992 · Cited by 38

Phosphatase PTPN4 Preferentially Inhibits TRIF-Dependent TLR4 Pathway by Dephosphorylating TRAM

Huai, W., Song, H., Wang, L., Li, B., Zhao, J., Han, L., Gao, C., Jiang, G., Zhang, L., & Zhao, W. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1402183 · Cited by 38

A Lactococcus lactis BFE920 feed vaccine expressing a fusion protein composed of the OmpA and FlgD antigens from Edwardsiella tarda was significantly better at protecting olive flounder (Paralichthys olivaceus) from edwardsiellosis than single antigen vaccines

Beck, B. R., Lee, S. H., Kim, D., Park, J. H., Lee, H. K., Kwon, S.-S., Lee, K. H., Lee, J. I., & Song, S. K. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.07.004 · Cited by 38

TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes

Schleimann, M. H., Kobberø, M.-L., Vibholm, L. K., Kjær, K., Giron, L. B., Busman‐Sahay, K., Chan, C. N., Nekorchuk, M. D., Schmidt, M., Wittig, B., et al. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.07.005 · Cited by 38

Systematic review and meta-analysis of human Toll-like receptors genetic polymorphisms for susceptibility to tuberculosis infection

Varshney, D., Singh, S. V., Sinha, E., Mohanty, K. K., Kumar, S., Barik, S. K., Patil, S. A., & Katara, P. (2022) · Cytokine · doi:10.1016/j.cyto.2021.155791 · Cited by 37

Ligation of TLR7 on CD19+CD1dhi B cells suppresses allergic lung inflammation via regulatory T cells

Khan, A. R., Amu, S., Saunders, S. P., Hams, E., Blackshields, G., Leonard, M. O., Weaver, C. T., Sparwasser, T. D., Sheils, O. M., & Fallon, P. G. (2015) · European Journal of Immunology · doi:10.1002/eji.201445211 · Cited by 38

Innate Receptors and Cellular Defense against Pulmonary Infections

Werner, J. L., & Steele, C. H. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400978 · Cited by 40

Radiation takes its Toll

Ratikan, J. A., Micewicz, E. D., Xie, M. W., & Schaue, D. (2015) · Cancer Letters · doi:10.1016/j.canlet.2015.03.031 · Cited by 40

Serum Amyloid A Induces Toll-Like Receptor 2-Dependent Inflammatory Cytokine Expression and Atrophy in C2C12 Skeletal Muscle Myotubes

Passey, S. L., Bozinovski, S., Vlahos, R., Anderson, G. P., & Hansen, M. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0146882 · Cited by 37

NF-κB signaling pathway as target for antiplatelet activity

Eduardo Fuentes, Q., Armando Rojas, R., & Palomo, I. F. (2016) · Blood Reviews · doi:10.1016/j.blre.2016.03.002 · Cited by 37

Unraveling the molecular pathways of DNA-methylation inhibitors: human endogenous retroviruses induce the innate immune response in tumors

Strick, R., Strissel, P. L., Baylin, S. B., & Chiappinelli, K. B. (2015) · OncoImmunology · doi:10.1080/2162402x.2015.1122160 · Cited by 37

Discrimination of Self and Non-Self Ribonucleic Acids

Gebhardt, A., Laudenbach, B. T., & Pichlmair, A. (2017) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2016.0092 · Cited by 37

Mucosal Vaccine Approaches for Prevention of HIV and SIV Transmission

Kozlowski, P. A., & Aldovini, A. (2018) · Current Immunology Reviews · doi:10.2174/1573395514666180605092054 · Cited by 38

Sphingosine kinase 2 is a negative regulator of inflammatory macrophage activation

Weigert, A., von Knethen, A., Thomas, D., de Faria, I. C. J., Namgaladze, D., Zezina, E. A., Fuhrmann, D. C., Petcherski, A., zu Heringdorf, D. M., Radeke, H. H., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2019.05.008 · Cited by 37

An intravital window to image the colon in real time

Rakhilin, N., Garrett, A., Eom, C., Chavez, K. R., Small, D. M., Daniel, A. R., Kaelberer, M. M., Mejooli, M. A., Huang, Q., Ding, S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13699-w · Cited by 40

RNF152 positively regulates TLR/IL‐1R signaling by enhancing MyD88 oligomerization

Xiong, M., Xu, Z., Li, Y., Wang, S., Wang, Y., & Ran, Y. (2020) · EMBO Reports · doi:10.15252/embr.201948860 · Cited by 37

TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes

Nguyen, B. N., Chávez‐Arroyo, A., Cheng, M. I., Krasilnikov, M., Louie, A., & Portnoy, D. A. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008622 · Cited by 37

Plasmodium infection inhibits tumor angiogenesis through effects on tumor-associated macrophages in a murine implanted hepatoma model

Wang, B., Li, Q., Wang, J., Zhao, S., Nashun, B., Li, Q., & Chen, X. (2020) · Cell Communication and Signaling · doi:10.1186/s12964-020-00570-5 · Cited by 38

Myeloid-Derived Suppressor Cells: Implications in the Resistance of Malignant Tumors to T Cell-Based Immunotherapy

Shi, H., Li, K., Ni, Y., Liang, X., & Zhao, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.707198 · Cited by 39

Targeting the “sweet spot” in septic shock – A perspective on the endothelial glycocalyx regulating proteins Heparanase-1 and -2

Pape, T., Hunkemöller, A. M., Kümpers, P., Haller, H. G., David, S., & Stahl, K. (2021) · Matrix Biology Plus · doi:10.1016/j.mbplus.2021.100095 · Cited by 37

Immmunoinformatics‐based design of a multi‐epitope vaccine with CTLA‐4 extracellular domain to combat Helicobacter pylori

Ru, Z., Yu, M., Zhu, Y., Chen, Z., Zhang, F., Zhang, Z., & Ding, J. (2022) · The FASEB Journal · doi:10.1096/fj.202101538rr · Cited by 37

STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation

Xu, J., Lee, M. H., Chakhtoura, M., Green, B. L., Kotredes, K. P., Chain, R. W., Sriram, U., Gamero, A. M., & Gallucci, S. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1500152 · Cited by 39

A poly(beta-amino ester) activates macrophages independent of NF-κB signaling

Dold, N. M., Zeng, Q., Zeng, X., & Jewell, C. M. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.12.040 · Cited by 37

Molecular basis of neurophysiological and antioxidant roles of Szechuan pepper

Deng, S., Rong, H., Tu, H., Zheng, B., Mu, X., Zhu, L., Xu, Z., Peng, W., Wu, M., Zhang, E., et al. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.108696 · Cited by 37

Immunostimulatory polysaccharide isolated from the leaves of Diospyros kaki Thumb modulate macrophage via TLR2

Lee, S.-G., Jung, J., Shin, J., Shin, K., Cho, C., Rhee, Y.-K., Hong, H., & Lee, K. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.06.023 · Cited by 37

Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome

Yan, T., Julio, A. R., Villanueva, M., Jones, A. E., Ball, A. B., Boatner, L. M., Turmon, A. C., Nguyễn, K. B., Yen, S. L., Desai, H. S., et al. (2023) · Cell chemical biology · doi:10.1016/j.chembiol.2023.06.008 · Cited by 37

IRAK-4 inhibition: emavusertib for the treatment of lymphoid and myeloid malignancies

Parrondo, R. D., Iqbal, M., von Roemeling, R., Roemeling, C. A. V., & Tun, H. W. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1239082 · Cited by 36

Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression

Hu, X., Han, C., Jin, J., Qin, K., Zhang, H., Li, T., Li, N., & Cao, X. (2016) · Scientific Reports · doi:10.1038/srep26252 · Cited by 36

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

Ricci-Azevedo, R., Roque‐Barreira, M. C., & Gay, N. J. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01820 · Cited by 36

Checkpoint inhibition in pediatric hematologic malignancies

Davis, K. L., Agarwal, A. M., & Verma, A. R. (2017) · Pediatric Hematology and Oncology · doi:10.1080/08880018.2017.1383542 · Cited by 36

Naturally Derived Anti-HIV Polysaccharide Peptide (PSP) Triggers a Toll-Like Receptor 4-Dependent Antiviral Immune Response

Rodríguez-Valentín, M., Acevedo, S. N. L., Rivera, M., Ríos‐Olivares, E., Cubano, L. A., & Boukli, N. M. (2018) · Journal of Immunology Research · doi:10.1155/2018/8741698 · Cited by 36

Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy

Amon, L., Hatscher, L., Heger, L., Dudziak, D., & Lehmann, C. H. K. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12070663 · Cited by 37

The Anti-fibrotic Effects of Heat-Killed Akkermansia muciniphila MucT on Liver Fibrosis Markers and Activation of Hepatic Stellate Cells

Raftar, S. K. A., Abdollahiyan, S., Azimirad, M., Yadegar, A., Vaziri, F., Moshiri, A., Siadat, S. D., & Zali, M. R. (2021) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-020-09733-9 · Cited by 37

The Emerging Role of RNA Modifications in the Regulation of Antiviral Innate Immunity

Tong, J., Zhang, W., Chen, Y., Yuan, Q., Qin, N.-N., & Qu, G. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.845625 · Cited by 37

The Role of Ten-Eleven Translocation Proteins in Inflammation

Gerecke, C., Rodrigues, C. E., Homann, T., & Kleuser, B. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.861351 · Cited by 36

Pervasive tandem duplications and convergent evolution shape coral genomes

Noël, B., Denœud, F., Rouan, A., Buitrago‐López, C., Capasso, L., Poulain, J., Boissin, É., Pousse, M., Silva, C. D., Couloux, A., et al. (2023) · Genome biology · doi:10.1186/s13059-023-02960-7 · Cited by 41

Integrative Development of a TLR8 Agonist for Ovarian Cancer Chemoimmunotherapy

Monk, B. J., Facciabene, A., Brady, W. E., Aghajanian, C. A., Fracasso, P. M., Walker, J. L., Lankes, H. A., Manjarrez, K. L., Danet-Desnoyers, G.-A., Bell‐McGuinn, K. M., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-16-1453 · Cited by 37

Interface Oral Health Science 2016

Takahashi, N., Sasaki, K., & Suzuki, O. (2016) · Springer eBooks · doi:10.1007/978-981-10-1560-1 · Cited by 36

Type I interferons and MAVS signaling are necessary for tissue resident memory CD8+ T cell responses to RSV infection

Varese, A., Nakawesi, J., Farias, A., Kirsebom, F. C. M., Paulsen, M., Nuriev, R. I., & Johansson, C. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010272 · Cited by 36

Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth

Li, L., Yang, J., Jiang, Y., Tu, J., & Schust, D. J. (2015) · Molecular Human Reproduction · doi:10.1093/molehr/gav001 · Cited by 35

Toll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints

Barreto, G., Sandelin, J., Salem, A., Nordström, D., & Waris, E. (2017) · Acta Orthopaedica · doi:10.1080/17453674.2017.1281058 · Cited by 35

Biosynthesis and structure–activity relationships of the lipid a family of glycolipids

Xiao, X., Sankaranarayanan, K., & Khosla, C. (2017) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2017.07.008 · Cited by 35

Mast cell tryptase – Marker and maker of cardiovascular diseases

Mohajeri, M., Kovanen, P. T., Bianconi, V., Pirro, M., Cicero, A. F. G., & Sahebkar, A. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.03.008 · Cited by 36

Escalating Threat Levels of Bacterial Infection Can Be Discriminated by Distinct MAPK and NF-κB Signaling Dynamics in Single Host Cells

Lane, K. M., Andres-Terrè, M., Kudo, T., Monack, D. M., & Covert, M. W. (2019) · Cell Systems · doi:10.1016/j.cels.2019.02.008 · Cited by 36

Synthesis and Evaluation of Novel TLR2 Agonists as Potential Adjuvants for Cancer Vaccines

Lu, B. L., Williams, G. M., Verdon, D. J., Dunbar, P. R., & Brimble, M. A. (2019) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.9b01044 · Cited by 35

The prognostic role of tissue TLR2 and TLR4 in colorectal cancer

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