The code and beyond: transcription regulation by the RNA polymerase II carboxy-terminal domain

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Human TFIIH Kinase CDK7 Regulates Transcription-Associated Chromatin Modifications

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RNA-modifying proteins as anticancer drug targets

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CDK9: A Comprehensive Review of Its Biology, and Its Role as a Potential Target for Anti-Cancer Agents

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Phase separation of RNA-binding protein promotes polymerase binding and transcription

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RNA polymerase II activity revealed by GRO-seq and pNET-seq in Arabidopsis

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Transcriptional Control of Circadian Rhythms and Metabolism: A Matter of Time and Space

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Dosage Compensation of the X Chromosome: A Complex Epigenetic Assignment Involving Chromatin Regulators and Long Noncoding RNAs

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Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III

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The essential and multifunctional TFIIH complex

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CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genes

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PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency

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RNA and liquid-liquid phase separation

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Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast

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Tracking chromatin state changes using nanoscale photo-proximity labelling

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R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes

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Therapeutic targeting of transcriptional cyclin-dependent kinases

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Anticancer mechanism of coumarin-based derivatives

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Non-canonical DNA/RNA structures during Transcription-Coupled Double-Strand Break Repair: Roadblocks or Bona fide repair intermediates?

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Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks

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Genomic regulation of transcription and RNA processing by the multitasking Integrator complex

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BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genomePreprint

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Transcription Factor DynamicsPreprint

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Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo

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ENL initiates multivalent phase separation of the super elongation complex (SEC) in controlling rapid transcriptional activation

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The logic of protein post‐translational modifications (PTMs): Chemistry, mechanisms and evolution of protein regulation through covalent attachments

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CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stabilityPreprint

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Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction

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Nascent RNA and the Coordination of Splicing with TranscriptionPreprint

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Chromatin dependencies in cancer and inflammation

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RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control

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Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting

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Discovery of 3-Benzyl-1-( trans -4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors

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The cryoelectron microscopy structure of the human CDK-activating kinase

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Mechanisms of Transcription Elongation Factor DSIF (Spt4–Spt5)

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Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis

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Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes

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Depicting HIV-1 Transcriptional Mechanisms: A Summary of What We Know

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WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin

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G 1 cyclin–Cdk promotes cell cycle entry through localized phosphorylation of RNA polymerase II

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Widespread and precise reprogramming of yeast protein–genome interactions in response to heat shockPreprint

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Regulation of RAD51 at the Transcriptional and Functional Levels: What Prospects for Cancer Therapy?

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Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription

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Influenza virus infection causes global RNAPII termination defects

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Peptidyl Arginine Deiminase 2 (PADI2)-Mediated Arginine Citrullination Modulates Transcription in Cancer

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Live imaging of transcription sites using an elongating RNA polymerase II–specific probe

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The Integrator complex at the crossroad of coding and noncoding RNA

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The Promise and Current Status of CDK12/13 Inhibition for the Treatment of Cancer

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Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries

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RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting

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The C-Terminal Domain of RNA Polymerase II Is a Multivalent Targeting Sequence that Supports Drosophila Development with Only Consensus Heptads

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Distinct patterns of histone acetyltransferase and Mediator deployment at yeast protein-coding genesPreprint

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Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

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Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene

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The Integrator Complex in Transcription and Development

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Angel or Devil ? - CDK8 as the new drug target

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BRD4: a general regulator of transcription elongation

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PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC

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Enhancer-Promoter Interaction of SELF PRUNING 5G Shapes Photoperiod Adaptation

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CDK11 is required for transcription of replication-dependent histone genes

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Coordinated Control of rRNA Processing by RNA Polymerase I

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Dual inhibition of CDK12 and CDK13 uncovers actionable vulnerabilities in patient-derived ovarian cancer organoids

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TFIIH: A multi-subunit complex at the cross-roads of transcription and DNA repair

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Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity

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RNA Polymerase II CTD Tyrosine 1 Is Required for Efficient Termination by the Nrd1-Nab3-Sen1 Pathway

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Chromatin-based mechanisms to coordinate convergent overlapping transcription

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CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci

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Oncogenic dysregulation of pre‐mRNA processing by protein kinases: challenges and therapeutic opportunities

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Cyclin‐dependent kinases: Masters of the eukaryotic universe

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Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters

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Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1

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Structural basis of INTAC-regulated transcription

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TAF15b, involved in the autonomous pathway for flowering, represses transcription of FLOWERING LOCUS C

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Key Concepts and Challenges in Archaeal Transcription

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