Cited by 512Alzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchNeuroinflammation and Neurodegeneration Mechanisms

γ-Secretase, notch, Aβ and alzheimer's disease: Where do the presenilins fit in?

Sisodia, Sangram S., St George-Hyslop, Peter H.·2002·Nature Reviews Neuroscience

Integrity signals

Registry

Crossref · 10.1038/nrn785

Cites

138 of 138 references verified0 citation errors · 0 not checkable

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Authors
Sisodia, S. S., & St George-Hyslop, P. H.
Affiliations
University of Chicago (US)
Venue
Nature Reviews Neuroscience
Published
2002-04
Volume
3
Issue
4
Pages
281-290
ISSN
  • 1471-003X (ISSN-L)
  • 1471-0048
OpenAlex
W1541961513
Cited by
512
References
138
Citations by year
2026: 1 · 2025: 4 · 2024: 7 · 2023: 3 · 2022: 11 · 2021: 9 · 2020: 10 · 2019: 12 · 2018: 11 · 2017: 15 · 2016: 15 · 2015: 13 · 2014: 27 · 2013: 15 · 2012: 23
FWCI
6.39
Type
journal article
Language
en
Open access
closed
Locations
  • Nature reviews. Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Howard Hughes Medical Institute
  • Alzheimer Society
Topics
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Keywords
gamma-secretase, presenilin, Notch signaling, amyloid precursor protein, Alzheimer's disease, amyloid-beta, nicastrin, proteolytic processing, alpha-secretase, beta-secretase, ErbB4, substrate transport
MeSH terms
Alzheimer Disease, Animals, Humans, Membrane Proteins, Endopeptidases, Trans-Activators, Amyloid beta-Peptides, Aspartic Acid Endopeptidases, Receptors, Notch, Amyloid Precursor Protein Secretases

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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