Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks

Mapping and analysis of chromatin state dynamics in nine human cell types

Ernst, J., Kheradpour, P., Mikkelsen, T. S., Shoresh, N., Ward, L. D., Epstein, C. B., Zhang, X., Wang, L., Issner, R., Coyne, M., et al. (2011) · Nature · doi:10.1038/nature09906 · Cited by 2,898 · see citing works

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

Bunting, S. F., Callén, E., Wong, N., Chen, H.-T., Polato, F., Gunn, A., Bothmer, A., Feldhahn, N., Fernandez-Capetillo, O., Cao, L., et al. (2010) · Cell · doi:10.1016/j.cell.2010.03.012 · Cited by 1,671 · see citing works

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T., & Kanemaki, M. (2009) · Nature Methods · doi:10.1038/nmeth.1401 · Cited by 1,663 · see citing works

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

The ENCODE Project Consortium (2011) · PLoS Biology · doi:10.1371/journal.pbio.1001046 · Cited by 1,495 · see citing works

Human CtIP promotes DNA end resection

Sartori, A. A., Lukas, C., Coates, J., Mistrik, M., Fu, S., Bartek, J., Baer, R., Lukas, J., & Jackson, S. P. (2007) · Nature · doi:10.1038/nature06337 · Cited by 1,362 · see citing works

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

Bouwman, P., Aly, A., Escandell, J. M., Pieterse, M., Bartkova, J., van der Gulden, H., Hiddingh, S., Thanasoula, M., Kulkarni, A., Yang, Q., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1831 · Cited by 1,001 · see citing works

Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Botuyan, M. V., Lee, J., Ward, I. M., Kim, J., Thompson, J. R., Chen, J., & Mer, G. (2006) · Cell · doi:10.1016/j.cell.2006.10.043 · Cited by 973 · see citing works

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

Escribano‐Diaz, C., Orthwein, A., Fradet‐Turcotte, A., Xing, M., Young, J. T. F., Tkáč, J., Cook, M. A., Rosebrock, A. P., Munro, M., Canny, M. D., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.001 · Cited by 903 · see citing works

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

Shanbhag, N. M., Rafalska-Metcalf, I. U., Balane-Bolivar, C., Janicki, S. M., & Greenberg, R. A. (2010) · Cell · doi:10.1016/j.cell.2010.04.038 · Cited by 737 · see citing works

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

Miller, K. M., Tjeertes, J. V., Coates, J., Legube, G., Polo, S. E., Britton, S., & Jackson, S. P. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1899 · Cited by 629 · see citing works

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

Chapman, J. R., Barral, P., Vannier, J., Borel, V., Steger, M., Tomás‐Loba, A., Sartori, A. A., Adams, I. R., Batista, F. D., & Boulton, S. J. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.01.002 · Cited by 624 · see citing works

53BP1 Regulates DSB Repair Using Rif1 to Control 5′ End Resection

Zimmermann, M., Lottersberger, F., Buonomo, S. B. C., Sfeir, A. J., & de Lange, T. (2013) · Science · doi:10.1126/science.1231573 · Cited by 594 · see citing works

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells.

Rouet, P., Smih, F., & Jasin, M. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.13.6064 · Cited by 571 · see citing works

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

Shibata, A., Moiani, D., Arvai, A. S., Perry, J. J. P., Harding, S. M., Genois, M., Maity, R., van Rossum-Fikkert, S. E., Kertokalio, A., Romoli, F., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.11.003 · Cited by 564 · see citing works

The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation

Dhayalan, A., Rajavelu, A., Rathert, P., Tamas, R., Jurkowska, R. Z., Ragozin, S., & Jeltsch, A. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.089433 · Cited by 560 · see citing works

ATM and Artemis promote homologous recombination of radiation‐induced DNA double‐strand breaks in G2

Beucher, A., Birraux, J., Tchouandong, L., Barton, O., Shibata, A., Conrad, S., Goodarzi, A. A., Krempler, A., Jeggo, P. A., & Löbrich, M. (2009) · The EMBO Journal · doi:10.1038/emboj.2009.276 · Cited by 548 · see citing works

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation

Edmunds, J. W., Mahadevan, L. C., & Clayton, A. L. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601967 · Cited by 547 · see citing works

Methylation of Histone H4 Lysine 20 Controls Recruitment of Crb2 to Sites of DNA Damage

Sanders, S. L., Portoso, M., Mata, J., Bähler, J., Allshire, R. C., & Kouzarides, T. (2004) · Cell · doi:10.1016/j.cell.2004.11.009 · Cited by 545 · see citing works

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

Tang, J., Cho, N. W., Cui, G., Manion, E. M., Shanbhag, N. M., Botuyan, M. V., Mer, G., & Greenberg, R. A. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2499 · Cited by 521 · see citing works

Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

Chiolo, I., Minoda, A., Colmenares, S. U., Polyzos, A. A., Costes, S. V., & Karpen, G. H. (2011) · Cell · doi:10.1016/j.cell.2011.02.012 · Cited by 516 · see citing works

High‐resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

Iacovoni, J. S., Caron, P., Lassadi, I., Nicolas, E., Massip, L., Trouche, D., & Legube, G. (2010) · The EMBO Journal · doi:10.1038/emboj.2010.38 · Cited by 515 · see citing works

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

Huertas, P., & Jackson, S. P. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808906200 · Cited by 511 · see citing works

Factors determining DNA double‐strand break repair pathway choice in G2 phase

Shibata, A., Conrad, S., Birraux, J., Geuting, V., Barton, O., Ismail, A., Kakarougkas, A., Meek, K., Taucher-Scholz, G., Löbrich, M., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.27 · Cited by 481 · see citing works

Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair

Berkovich, E., Monnat, R. J., & Kastan, M. B. (2007) · Nature Cell Biology · doi:10.1038/ncb1599 · Cited by 477 · see citing works

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

Pei, H., Zhang, L. M., Luo, K., Qin, Y., Chesi, M., Fei, Y. F., Bergsagel, P. L., Wang, L., You, Z., & Lou, Z. (2011) · Nature · doi:10.1038/nature09658 · Cited by 412 · see citing works

DNA Damage-Induced Cell Cycle Checkpoint Control Requires CtIP, a Phosphorylation-Dependent Binding Partner of BRCA1 C-Terminal Domains

Yu, X., & Chen, J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.21.9478-9486.2004 · Cited by 410 · see citing works

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

Virgilio, M. D., Callén, E., Yamane, A., Zhang, W., Janković, M., Gitlin, A. D., Feldhahn, N., Resch, W., Oliveira, T. Y., Chait, B. T., et al. (2013) · Science · doi:10.1126/science.1230624 · Cited by 401 · see citing works

Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase

Karanam, K., Kafri, R., Loewer, A., & Lahav, G. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.05.052 · Cited by 393 · see citing works

A library of TAL effector nucleases spanning the human genome

Kim, Y., Kweon, J., Kim, A., Chon, J. K., Yoo, J. Y., Kim, H. J., Kim, S., Lee, C., Jeong, E., Chung, E., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2517 · Cited by 371 · see citing works

Mechanisms of double-strand break repair in somatic mammalian cells

Hartlerode, A. J., & Scully, R. (2009) · Biochemical Journal · doi:10.1042/bj20090942 · Cited by 365 · see citing works

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

Soria, G., Polo, S. E., & Almouzni, G. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.06.002 · Cited by 342 · see citing works

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

Noon, A. T., Shibata, A., Rief, N., Löbrich, M., Stewart, G. S., Jeggo, P. A., & Goodarzi, A. A. (2010) · Nature Cell Biology · doi:10.1038/ncb2017 · Cited by 339 · see citing works

The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax

Goodarzi, A. A., Jeggo, P., & Lobrich, M. (2010) · DNA Repair · doi:10.1016/j.dnarep.2010.09.013 · Cited by 305 · see citing works

Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4Cdt2-Mediated PCNA-Dependent Degradation during DNA Damage

Oda, H., Hübner, M. R., Beck, D. B., Vermeulen, M., Hurwitz, J., Spector, D. L., & Reinberg, D. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.10.011 · Cited by 247 · see citing works

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells

Fattah, F. J., Lee, E. H., Weisensel, N. A., Wang, Y., Lichter, N., & Hendrickson, E. A. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000855 · Cited by 244 · see citing works

Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

Bothmer, A., Robbiani, D. F., Di Virgilio, M., Bunting, S. F., Klein, I. A., Feldhahn, N., Barlow, J., Chen, H.-T., Bosque, D., Callen, E., et al. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.03.019 · Cited by 244 · see citing works

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

Vezzoli, A., Bonadies, N., Allen, M. D., Freund, S. M. V., Santiveri, C. M., Kvinlaug, B. T., Huntly, B. J. P., Göttgens, B., & Bycroft, M. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1797 · Cited by 218 · see citing works

LEDGF (p75) promotes DNA-end resection and homologous recombination

Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, C. S., Petersen, N. H. T., Sorensen, P. H. B., Lukas, C., Bártek, J., et al. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2314 · Cited by 208 · see citing works

Recruitment of the Recombinational Repair Machinery to a DNA Double-Strand Break in Yeast

Wolner, B. S., Komen, S. V., Sung, P., & Peterson, C. L. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00242-9 · Cited by 198 · see citing works

Heterochromatin establishment in the context of genome-wide epigenetic reprogramming

Probst, A. V., & Almouzni, G. (2011) · Trends in Genetics · doi:10.1016/j.tig.2011.02.002 · Cited by 149 · see citing works

53BP1: function and mechanisms of focal recruitment

FitzGerald, J. E., Grenon, M., & Lowndes, N. F. (2009) · Biochemical Society Transactions · doi:10.1042/bst0370897 · Cited by 141 · see citing works

Cohesin Protects Genes against γH2AX Induced by DNA Double-Strand Breaks

Caron, P., Aymard, F., Iacovoni, J. S., Briois, S., Canitrot, Y., Bugler, B., Massip, L., Losada, A., & Legube, G. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002460 · Cited by 135 · see citing works

Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatinPreprint

Chantalat, S., Depaux, A., Héry, P., Barral, S., Thuret, J., Dimitrov, S. I., & Gérard, M. (2011) · Genome Research · doi:10.1101/gr.118091.110 · Cited by 119 · see citing works

Histone marks: repairing DNA breaks within the context of chromatin

Miller, K. M., & Jackson, S. P. (2012) · Biochemical Society Transactions · doi:10.1042/bst20110747 · Cited by 88 · see citing works

Common ground: small RNA programming and chromatin modifications

Lejeune, E., & Allshire, R. C. (2011) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2011.03.005 · Cited by 76 · see citing works

Impact of Histone H4 Lysine 20 Methylation on 53BP1 Responses to Chromosomal Double Strand Breaks

Hartlerode, A. J., Guan, Y., Rajendran, A., Ura, K., Schotta, G., Xie, A., Shah, J. V., & Scully, R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049211 · Cited by 70 · see citing works

Deciphering the chromatin landscape induced around DNA double strand breaks

Massip, L., Caron, P., Iacovoni, J. S., Trouche, D., & Legube, G. (2010) · Cell Cycle · doi:10.4161/cc.9.15.12412 · Cited by 68 · see citing works

Homologous chromosomes make contact at the sites of double-strand breaks in genes in somatic G 0 /G 1 -phase human cells

Gandhi, M., Evdokimova, V. N., Cuenco, K. T., Nikiforova, M. N., Kelly, L. M., Stringer, J. R., Bakkenist, C. J., & Nikiforov, Y. E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1205759109 · Cited by 52 · see citing works

Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation

Dumay, A., Laulier, C., Bertrand, P., Saintigny, Y., Lebrun, F., Vayssière, J.-L., & López, B. S. (2005) · Oncogene · doi:10.1038/sj.onc.1209344 · Cited by 49 · see citing works

Quantifying DNA double-strand breaks induced by site-specific endonucleases in living cells by ligation-mediated purification

Chailleux, C., Aymard, F., Caron, P., Daburon, V., Courilleau, C., Canitrot, Y., Legube, G., & Trouche, D. (2014) · Nature Protocols · doi:10.1038/nprot.2014.031 · Cited by 35 · see citing works

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36

Napierala, J. S., & Dent, S. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2370 · Cited by 22 · see citing works

Oogenesis: Active Heterochromatin

Finnegan, D. (2011) · Current Biology · doi:10.1016/j.cub.2011.07.029 · Cited by 3 · see citing works

DNA double-strand break repair-pathway choice in somatic mammalian cells

Scully, R., Panday, A., Elango, R., & Willis, N. A. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0152-0 · Cited by 1,445 · see citing works

Ribosome biogenesis in cancer: new players and therapeutic avenues

Pelletier, J., Thomas, G., & Volarević, S. (2017) · Nature reviews. Cancer · doi:10.1038/nrc.2017.104 · Cited by 802 · see citing works

R Loops: From Physiological to Pathological Roles

García‐Muse, T., & Aguilera, A. (2019) · Cell · doi:10.1016/j.cell.2019.08.055 · Cited by 676 · see citing works

Clear cell renal cell carcinoma ontogeny and mechanisms of lethality

Jonasch, E. W., Walker, C. L., & Rathmell, W. K. (2020) · Nature Reviews Nephrology · doi:10.1038/s41581-020-00359-2 · Cited by 647 · see citing works

Regulation of Single-Strand Annealing and its Role in Genome Maintenance

Bhargava, R., Onyango, D. O., & Stark, J. M. (2016) · Trends in Genetics · doi:10.1016/j.tig.2016.06.007 · Cited by 475 · see citing works

SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability

Pfister, S. X., Ahrabi, S., Zalmas, L., Sarkar, S., Aymard, F., Bachrati, C. Z., Helleday, T., Legube, G., Thangue, N. B. L., Porter, A. C. G., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.05.026 · Cited by 465 · see citing works

Nuclear ARP2/3 drives DNA break clustering for homology-directed repair

Schrank, B. R., Aparicio, T., Li, Y., Chang, W., Chait, B. T., Gundersen, G. G., Gottesman, M. E., & Gautier, J. (2018) · Nature · doi:10.1038/s41586-018-0237-5 · Cited by 400 · see citing works

Loop extrusion as a mechanism for formation of DNA damage repair foci

Arnould, C., Rocher, V., Finoux, A.-L., Clouaire, T., Li, K., Zhou, F., Caron, P., Mangeot, P. E., Ricci, E. P., Mourad, R., et al. (2021) · Nature · doi:10.1038/s41586-021-03193-z · Cited by 341 · see citing works

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Cohen, S., Puget, N., Lin, Y., Clouaire, T., Aguirrebengoa, M., Rocher, V., Pasero, P., Canitrot, Y., & Legube, G. (2018) · Nature Communications · doi:10.1038/s41467-018-02894-w · Cited by 338 · see citing works

DNA damage foci: Meaning and significance

Rothkamm, K., Barnard, S. G. R., Moquet, J., Ellender, M., Rana, Z., & Burdak‐Rothkamm, S. (2015) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21944 · Cited by 335 · see citing works

Chromatin and nucleosome dynamics in DNA damage and repairPreprint

Hauer, M., & Gasser, S. M. (2017) · Genes & Development · doi:10.1101/gad.307702.117 · Cited by 320 · see citing works

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

Yasuhara, T., Kato, R., Hagiwara, Y., Shiotani, B., Yamauchi, M., Nakada, S., Shibata, A., & Miyagawa, K. (2018) · Cell · doi:10.1016/j.cell.2018.08.056 · Cited by 317 · see citing works

Coevolution between transposable elements and recombination

Kent, T. V., Uzunović, J., & Wright, S. I. (2017) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0458 · Cited by 312 · see citing works

How cells ensure correct repair of DNA double-strand breaks

Her, J., & Bunting, S. F. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.tm118.000371 · Cited by 304 · see citing works

Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

Pfister, S. X., Markkanen, E., Jiang, Y., Sarkar, S., Woodcock, M., Orlando, G., Mavrommati, I., Pai, C., Zalmas, L., Drobnitzky, N., et al. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.09.015 · Cited by 300 · see citing works

Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures

Clouaire, T., Rocher, V., Lashgari, A., Arnould, C., Aguirrebengoa, M., Biernacka, A., Skrzypczak, M., Aymard, F., Fongang, B., Dojer, N., et al. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.08.020 · Cited by 300 · see citing works

Marked for death: Targeting epigenetic changes in cancer

Pfister, S. X., & Ashworth, A. (2017) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2016.256 · Cited by 288 · see citing works

Dual Chromatin and Cytoskeletal Remodeling by SETD2

Park, I. Y., Powell, R. T., Tripathi, D. N., Dere, R., Ho, T. H., Blasius, T. L., Chiang, Y.-C., Davis, I. J., Fahey, C. C., Hacker, K. E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.07.005 · Cited by 268 · see citing works

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

Aymard, F., Aguirrebengoa, M., Guillou, E., Javierre, B. M., Bugler, B., Arnould, C., Rocher, V., Iacovoni, J. S., Biernacka, A., Skrzypczak, M., et al. (2017) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3387 · Cited by 263 · see citing works

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation

Jacquet, K., Fradet‐Turcotte, A., Avvakumov, N., Lambert, J., Lopez‐Roques, C., PANDITA, R. K., Paquet, É. R., Herst, P. M., Gingras, A., Pandita, T. K., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.03.031 · Cited by 260 · see citing works

Temporal and Spatial Uncoupling of DNA Double Strand Break Repair Pathways within Mammalian Heterochromatin

Tsouroula, K., Furst, A., Rogier, M., Heyer, V., Maglott, A., Ferrand, A., Reina‐San‐Martin, B., & Soutoglou, E. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.06.002 · Cited by 250 · see citing works

Histone methylation and the DNA damage response

Gong, F., & Miller, K. M. (2017) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2017.09.003 · Cited by 247 · see citing works

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stagePreprint

van Sluis, M., & McStay, B. (2015) · Genes & Development · doi:10.1101/gad.260703.115 · Cited by 241 · see citing works

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

Gong, F., Chiu, L.-Y., Cox, B., Aymard, F., Clouaire, T., Leung, J. W., Cammarata, M., Perez, M., Agarwal, P., Brodbelt, J. S., et al. (2015) · Genes & Development · doi:10.1101/gad.252189.114 · Cited by 247 · see citing works

ALTernative Telomere Maintenance and Cancer

Dilley, R. L., & Greenberg, R. A. (2015) · Trends in cancer · doi:10.1016/j.trecan.2015.07.007 · Cited by 241 · see citing works

Transcription-mediated replication hindrance: a major driver of genome instabilityPreprint

Gómez‐González, B., & Aguilera, A. (2019) · Genes & Development · doi:10.1101/gad.324517.119 · Cited by 224 · see citing works

The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair

Jasin, M., & Haber, J. E. (2016) · DNA repair · doi:10.1016/j.dnarep.2016.05.001 · Cited by 220 · see citing works

A Macrohistone Variant Links Dynamic Chromatin Compaction to BRCA1-Dependent Genome Maintenance

Khurana, S., Kruhlak, M. J., Kim, J., Tran, A. D., Liu, J., Nyswaner, K., Shi, L., Jailwala, P., Sung, M.-H., Hakim, O., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.07.024 · Cited by 220 · see citing works

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner

Collins, P. L., Purman, C. E., Porter, S. I., Nganga, V. K., Saini, A., Hayer, K. E., Gurewitz, G. L., Sleckman, B. P., Bednarski, J. J., Bassing, C. H., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16926-x · Cited by 215 · see citing works

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

Lu, W.-T., Hawley, B. R., Skalka, G., Baldock, R. A., Smith, E. M., Bader, A. S., Malewicz, M., Watts, F. Z., Wilczynska, A., & Bushell, M. (2018) · Nature Communications · doi:10.1038/s41467-018-02893-x · Cited by 217 · see citing works

Nuclear position dictates DNA repair pathway choice

Lemaître, C., Grabarz, A., Tsouroula, K., Andronov, L., Furst, A., Pankotai, T., Heyer, V., Rogier, M., Attwood, K. M., Kessler, P., et al. (2014) · Genes & Development · doi:10.1101/gad.248369.114 · Cited by 209 · see citing works

H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

Saredi, G., Huang, H., Hammond, C. M., Alabert, C., Bekker‐Jensen, S., Forné, I., Reverón-Gómez, N., Foster, B. M., Mlejnkova, L. J., Bartke, T., et al. (2016) · Nature · doi:10.1038/nature18312 · Cited by 212 · see citing works

Alternative end-joining repair pathways are the ultimate backup for abrogated classical non-homologous end-joining and homologous recombination repair: Implications for the formation of chromosome translocations

Iliakis, G. E., Murmann-Konda, T., & Soni, A. (2015) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2015.07.001 · Cited by 199 · see citing works

Site-specific integration in CHO cells mediated by CRISPR/Cas9 and homology-directed DNA repair pathway

Lee, J. S., Kallehauge, T. B., Pedersen, L. E., & Kildegaard, H. F. (2015) · Scientific Reports · doi:10.1038/srep08572 · Cited by 196 · see citing works

The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo

Powers, N. R., Parvanov, E. D., Baker, C. L., Walker, M., Petkov, P. M., & Paigen, K. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006146 · Cited by 196 · see citing works

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Schep, R., Brinkman, E. K., Leemans, C., Vergara, X., van der Weide, R. H., Morris, B., van Schaik, T., Manzo, S. G., Peric‐Hupkes, D., van den Berg, J., et al. (2021) · Molecular Cell · doi:10.1016/j.molcel.2021.03.032 · Cited by 192 · see citing works

The nucleosome remodeling and deacetylase complex in development and disease

Basta, J., & Rauchman, M. (2015) · Translational Research · doi:10.1016/j.trsl.2014.05.003 · Cited by 191 · see citing works

DNA repair mechanisms and their clinical impact in glioblastoma

Erasimus, H., Gobin, M., Niclou, S. P., & Dyck, E. V. (2016) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2016.05.005 · Cited by 189 · see citing works

Histone demethylase KDM5A regulates the ZMYND8–NuRD chromatin remodeler to promote DNA repair

Gong, F., Clouaire, T., Aguirrebengoa, M., Legube, G., & Miller, K. M. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201611135 · Cited by 182 · see citing works

m5C modification of mRNA serves a DNA damage code to promote homologous recombination

Chen, H., Yang, H., Zhu, X., Yadav, T., Ouyang, J., Truesdell, S. S., Tan, J. J., Wang, Y., Duan, M.-H., Wei, L., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16722-7 · Cited by 181 · see citing works

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Kanu, N., Gronroos, E. C., Martinez, P., Burrell, R. A., Goh, X. Y., Bártková, J., Maya‐Mendoza, A., Mistrík, M., Rowan, A., Patel, H., et al. (2015) · Oncogene · doi:10.1038/onc.2015.24 · Cited by 181 · see citing works

Chromatin compartmentalization regulates the response to DNA damage

Arnould, C., Rocher, V., Saur, F., Bader, A. S., Muzzopappa, F., Collins, S., Lesage, E., Bozec, B. L., Puget, N., Clouaire, T., et al. (2023) · Nature · doi:10.1038/s41586-023-06635-y · Cited by 177 · see citing works

ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB

Teng, Y., Yadav, T., Duan, M.-H., Tan, J. J., Xiang, Y., Gao, B., Xu, J., Liang, Z., Liu, Y., Nakajima, S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06586-3 · Cited by 179 · see citing works

Regulation of repair pathway choice at two-ended DNA double-strand breaks

Shibata, A. (2017) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2017.07.011 · Cited by 176 · see citing works

Checkpoint Responses to DNA Double-Strand Breaks

Waterman, D. P., Haber, J. E., & Smolka, M. B. (2020) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-011520-104722 · Cited by 178 · see citing works

RNA transcripts stimulate homologous recombination by forming DR-loops

Ouyang, J., Yadav, T., Zhang, J., Yang, H., Rheinbay, E., Guo, H., Haber, D. A., Lan, L., & Zou, L. (2021) · Nature · doi:10.1038/s41586-021-03538-8 · Cited by 167 · see citing works

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation

Yang, H., Wang, Y., Xiang, Y., Yadav, T., Ouyang, J., Phoon, L. Y., Zhu, X., Shi, Y., Zou, L., & Lan, L. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2116251119 · Cited by 166 · see citing works

A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice

Pai, C., Deegan, R. S., Subramanian, L., Gal, C., Sarkar, S., Blaikley, E., Walker, C. A., Hulme, L., Bernhard, E. J., Codlin, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms5091 · Cited by 166 · see citing works

Epigenome Maintenance in Response to DNA Damage

Dabin, J., Fortuny, A., & Polo, S. E. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.04.006 · Cited by 161 · see citing works

LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2

Li, H., An, J., Wu, M., Zheng, Q., Gui, X., Li, T., Pu, H., & Lu, D. (2015) · Oncotarget · doi:10.18632/oncotarget.4443 · Cited by 160 · see citing works

DSBCapture: in situ capture and sequencing of DNA breaks

Lensing, S. V., Marsico, G., Hänsel‐Hertsch, R., Lam, E. Y. N., Tannahill, D., & Balasubramanian, S. (2016) · Nature Methods · doi:10.1038/nmeth.3960 · Cited by 155 · see citing works

PARP Inhibitors in Ovarian Cancer

Mittica, G., Ghisoni, E., Giannone, G., Genta, S., Aglietta, M., Sapino, A., & Valabrega, G. (2018) · Recent Patents on Anti-Cancer Drug Discovery · doi:10.2174/1574892813666180305165256 · Cited by 158 · see citing works

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes

Chakraborty, A., Tapryal, N., Venkova, T., Horikoshi, N., PANDITA, R. K., Sarker, A. H., Sarkar, P. S., Pandita, T. K., & Hazra, T. K. (2016) · Nature Communications · doi:10.1038/ncomms13049 · Cited by 155 · see citing works

Epigenetics, DNA damage, and aging

Soto-Palma, C., Niedernhofer, L., Faulk, C. D., & Dong, X. (2022) · Journal of Clinical Investigation · doi:10.1172/jci158446 · Cited by 112 · see citing works

DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks

Li, L., Germain, D. R., Poon, H.-Y., Hildebrandt, M. R., Monckton, E. A., McDonald, D., Hendzel, M. J., & Godbout, R. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00415-16 · Cited by 152 · see citing works

Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox

Vítor, A. C., Huertas, P., Legube, G., & de Almeida, S. F. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00024 · Cited by 148 · see citing works

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

Nishi, R., Wijnhoven, P. W. G., le Sage, C., Tjeertes, J., Galanty, Y., Forment, J. V., Clague, M. J., Urbé, S., & Jackson, S. P. (2014) · Nature Cell Biology · doi:10.1038/ncb3028 · Cited by 148 · see citing works

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

Wei, L., Nakajima, S., Böhm, S., Bernstein, K. A., Shen, Z., Tsang, M., Levine, A. S., & Lan, L. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1507105112 · Cited by 147 · see citing works

SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia

Mar, B. G., Chu, S. H., Kahn, J. D., Krivtsov, A. V., Koche, R. P., Castellano, C. A., Kotlier, J. L., Zon, R. L., McConkey, M. E., Chabon, J. R., et al. (2017) · Blood · doi:10.1182/blood-2017-03-775569 · Cited by 139 · see citing works

Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care

Marnef, A., Cohen, S., & Legube, G. (2017) · Journal of Molecular Biology · doi:10.1016/j.jmb.2017.03.024 · Cited by 138 · see citing works

Poly (ADP-Ribose) Polymerase Inhibitors: Talazoparib in Ovarian Cancer and Beyond

Boussios, S., Abson, C., Moschetta, M., Rassy, E., Karathanasi, A., Bhat, T., Ghumman, F. I. A., Sheriff, M., & Pavlidis, N. A. (2020) · Drugs in R&D · doi:10.1007/s40268-020-00301-8 · Cited by 140 · see citing works

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrityPreprint

Kim, J. J., Lee, S. Y., Gong, F., Battenhouse, A. M., Boutz, D. R., Bashyal, A., Refvik, S. T., Chiang, C., Xhemalçe, B., Paull, T. T., et al. (2019) · Genes & Development · doi:10.1101/gad.331231.119 · Cited by 139 · see citing works

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

Deshpande, R. A., Myler, L. R., Soniat, M. M., Makharashvili, N., Lee, L., Lees‐Miller, S. P., Finkelstein, I. J., & Paull, T. T. (2020) · Science Advances · doi:10.1126/sciadv.aay0922 · Cited by 138 · see citing works

DNA–RNA hybrids: the risks of DNA breakage during transcription

Aguilera, A., & Gómez‐González, B. (2017) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3395 · Cited by 137 · see citing works

Nuclear Actin and Actin-Binding Proteins in DNA Repair

Hurst, V., Shimada, K., & Gasser, S. M. (2019) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.02.010 · Cited by 133 · see citing works

Targeting epigenetic regulators as a promising avenue to overcome cancer therapy resistance

Song, J., Yang, P. X., Chen, C., Ding, W., Tillement, O., Bai, H., & Zhang, S. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02266-z · Cited by 145 · see citing works

A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

Iannelli, F., Galbiati, A., Capozzo, I., Nguyen, Q. H., Magnuson, B., Michelini, F., D’Alessandro, G., Cabrini, M., Roncador, M., Francia, S., et al. (2017) · Nature Communications · doi:10.1038/ncomms15656 · Cited by 124 · see citing works

Replication Stress in Mammalian Cells and Its Consequences for Mitosis

Gelot, C., Magdalou, I., & López, B. S. (2015) · Genes · doi:10.3390/genes6020267 · Cited by 123 · see citing works

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

Meisenberg, C., Pinder, S. I., Hopkins, S. R., Wooller, S. K., Benstead-Hume, G., Pearl, F. M. G., Jeggo, P. A., & Downs, J. A. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.11.001 · Cited by 126 · see citing works

An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair

Jha, D. K., & Strahl, B. D. (2014) · Nature Communications · doi:10.1038/ncomms4965 · Cited by 123 · see citing works

53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination

Callén, E., Zong, D., Wu, W., Wong, N., Stanlie, A., Ishikawa, M., Pavani, R., Dumitrache, L. C., Byrum, A. K., Mendez‐Dorantes, C., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.09.024 · Cited by 120 · see citing works

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

Caron, P., Choudjaye, J., Clouaire, T., Bugler, B., Daburon, V., Aguirrebengoa, M., Mangeat, T., Iacovoni, J. S., Álvarez-Quilón, A., Cortés‐Ledesma, F., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.10.024 · Cited by 124 · see citing works

Breaks in the 45S rDNA Lead to Recombination-Mediated Loss of Repeats

Warmerdam, D. O., van den Berg, J., & Medema, R. H. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.02.048 · Cited by 112 · see citing works

PRDM9, a driver of the genetic map

Grey, C., Baudat, F., & de Massy, B. (2018) · PLoS Genetics · doi:10.1371/journal.pgen.1007479 · Cited by 114 · see citing works

Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks

Gürsoy-Yüzügüllü, Ö., House, N. C. M., & Price, B. D. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.11.021 · Cited by 110 · see citing works

A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis

Löbrich, M., & Jeggo, P. A. (2017) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2017.06.011 · Cited by 114 · see citing works

The tale of a tail: histone H4 acetylation and the repair of DNA breaks

Dhar, S., Gürsoy-Yüzügüllü, Ö., Parasuram, R., & Price, B. D. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0284 · Cited by 113 · see citing works

BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair‡

Sessa, G., Gómez‐González, B., Silva, S. D. R., Calero, C. P., Beaurepere, R., Barroso, S. I., Martineau, S., Martin, C. A., Ehlén, Å., Martínez, J. S., et al. (2021) · The EMBO Journal · doi:10.15252/embj.2020106018 · Cited by 113 · see citing works

A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatinPreprint

Janssen, A., Breuer, G. A., Brinkman, E. K., van der Meulen, A. I., Borden, S. V., van Steensel, B., Bindra, R. S., LaRocque, J. R., & Karpen, G. H. (2016) · Genes & Development · doi:10.1101/gad.283028.116 · Cited by 109 · see citing works

A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repairPreprint

Marnef, A., Finoux, A.-L., Arnould, C., Guillou, E., Daburon, V., Rocher, V., Mangeat, T., Mangeot, P. E., Ricci, E. P., & Legube, G. (2019) · Genes & Development · doi:10.1101/gad.324012.119 · Cited by 112 · see citing works

Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness

Kari, V., Mansour, W. Y., Raul, S. K., Baumgart, S. J., Mund, A., Grade, M., Sirma, H., Simon, R., Will, H., Dobbelstein, M., et al. (2016) · EMBO Reports · doi:10.15252/embr.201642352 · Cited by 111 · see citing works

H3K36me3, message from chromatin to DNA damage repair

Sun, Z., Zhang, Y., Jia, J., Fang, Y., Tang, Y., Wu, H., & Fang, D. (2020) · Cell & Bioscience · doi:10.1186/s13578-020-0374-z · Cited by 109 · see citing works

DNA double strand break repair pathway choice: a chromatin based decision?

Clouaire, T., & Legube, G. (2015) · Nucleus · doi:10.1080/19491034.2015.1010946 · Cited by 108 · see citing works

A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks

Clouaire, T., & Legube, G. (2019) · Trends in Genetics · doi:10.1016/j.tig.2019.02.003 · Cited by 107 · see citing works

Life or Death after a Break: What Determines the Choice?

Krenning, L., van den Berg, J., & Medema, R. H. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.08.023 · Cited by 108 · see citing works

Human CDK12 and CDK13, multi-tasking CTD kinases for the new millenium

Greenleaf, A. L. (2018) · Transcription · doi:10.1080/21541264.2018.1535211 · Cited by 105 · see citing works

Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair

Korsholm, L. M., Gál, Z., Lin, L., Quevedo, O., Ahmad, D. A., Dulina, E., Luo, Y., Bártek, J., & Larsen, D. H. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz518 · Cited by 102 · see citing works

Cell cycle-dependent control of homologous recombination

Zhao, X., Wei, C., Li, J., Xing, P., Li, J., Zheng, S., & Chen, X. (2017) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmx055 · Cited by 103 · see citing works

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks

Domingo‐Prim, J., Endara-Coll, M., Bonath, F., Jimeno, S., Prados‐Carvajal, R., Friedländer, M. R., Huertas, P., & Visa, N. (2019) · Nature Communications · doi:10.1038/s41467-019-10153-9 · Cited by 104 · see citing works

Relationship among DNA double‐strand break (DSB), DSB repair, and transcription prevents genome instability and cancer

Ui, A., Chiba, N., & Yasui, A. (2020) · Cancer Science · doi:10.1111/cas.14404 · Cited by 104 · see citing works

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair

Lu, H., Shamanna, R. A., de Freitas, J. K., Okur, M. N., Khadka, P., Kulikowicz, T., Holland, P. P., Tian, J. Y., Croteau, D. L., Davis, A. J., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-02146-3 · Cited by 104 · see citing works

The diverse roles of SPOP in prostate cancer and kidney cancer

Wang, Z. P., Song, Y., Ye, M., Dai, X., Zhu, X., & Wei, W. (2020) · Nature Reviews Urology · doi:10.1038/s41585-020-0314-z · Cited by 101 · see citing works

Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage

Burger, K., Schlackow, M., Potts, M., Hester, S., Mohammed, S., & Gullerová, M. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201612131 · Cited by 103 · see citing works

The multi-functionality of UHRF1: epigenome maintenance and preservation of genome integrity

Mancini, M., Magnani, E., Macchi, F., & Bonapace, I. M. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab293 · Cited by 99 · see citing works

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair

Pazi, K., Chathoth, K. T., Taylor, G. C. A., Meynert, A. M., Ballinger, T. J., Kelder, M. J. E., Lalevée, S., Sanli, I., Feil, R., & Wood, A. J. (2018) · PLoS Biology · doi:10.1371/journal.pbio.2005595 · Cited by 99 · see citing works

Deciphering the BRCA1 Tumor Suppressor Network

Jiang, Q., & Greenberg, R. A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.r115.667931 · Cited by 95 · see citing works

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

Kalousi, A., Hoffbeck, A.-S., Selemenakis, P., Pinder, J. B., Savage, K. I., Khanna, K. K., Brino, L., Dellaire, G., Gorgoulis, V. G., & Soutoglou, E. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.03.005 · Cited by 92 · see citing works

RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks

Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, L. J., Ćejka, P., Croteau, D. L., & Bohr, V. A. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.079 · Cited by 95 · see citing works

Single-molecule imaging reveals the mechanism of Exo1 regulation by single-stranded DNA binding proteins

Myler, L. R., Gallardo, I. F., Zhou, Y., Gong, F., Yang, S.-H., Wold, M. S., Miller, K. M., Paull, T. T., & Finkelstein, I. J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516674113 · Cited by 94 · see citing works

Preserving genome integrity and function: the DNA damage response and histone modifications

Kim, J. J., Lee, S. Y., & Miller, K. M. (2019) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2019.1620676 · Cited by 95 · see citing works

DNA double strand break repair pathway choice: a chromatin based decision?

Clouaire, T., & Legube, G. (2015) · Nucleus · doi:10.1080/19491034.2015.1010946 · Cited by 108 · see citing works

New roles for RAD52 in DNA repair

Xue, C., & Greene, E. C. (2018) · Cell Research · doi:10.1038/s41422-018-0105-8 · Cited by 8 · see citing works

Transcriptionally tailored break repair

Zlotorynski, E. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0069-z

Regulation of DNA break repair by transcription and RNA

Ouyang, J., Lan, L., & Zou, L. (2017) · Science China Life Sciences · doi:10.1007/s11427-017-9164-1 · Cited by 18 · see citing works

Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid

Muñoz-Galván, S., Jimeno, S., Rothstein, R. J., & Aguilera, A. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003237 · Cited by 89 · see citing works