The many functions of ESCRTs

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

Shedding light on the cell biology of extracellular vesicles

van Niel, G., D'Angelo, G., & Raposo, G. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.125 · Cited by 8,369

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

Baietti, M. F., Zhang, Z., Mortier, E., Melchior, A., Degeest, G., Geeraerts, A., Ivarsson, Y., Depoortere, F., Coomans, C., Vermeiren, E., et al. (2012) · Nature Cell Biology · doi:10.1038/ncb2502 · Cited by 1,899

Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I

Katzmann, D. J., Babst, M., & Emr, S. D. (2001) · Cell · doi:10.1016/s0092-8674(01)00434-2 · Cited by 1,473

The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes

Itakura, E., Kishi‐Itakura, C., & Mizushima, N. (2012) · Cell · doi:10.1016/j.cell.2012.11.001 · Cited by 1,385

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

Garrus, J. E., von Schwedler, U. K., Pornillos, O. W., Morham, S. G., Zavitz, K. H., Wang, H. E., Wettstein, D. A., Stray, K. M., Côté, M., Rich, R. L., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00506-2 · Cited by 1,369

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

Raiborg, C., & Stenmark, H. (2009) · Nature · doi:10.1038/nature07961 · Cited by 1,359

Nuclear envelope rupture and repair during cancer cell migration

Denais, C. M., Gilbert, R. M., Isermann, P., McGregor, A. L., te Lindert, M., Weigelin, B., Davidson, P. M., Friedl, P., Wolf, K., & Lammerding, J. (2016) · Science · doi:10.1126/science.aad7297 · Cited by 1,318

DNA breaks and chromosome pulverization from errors in mitosis

Crasta, K., Ganem, N. J., Dagher, R., Lantermann, A. B., Ivanova, E. V., Pan, Y., Nezi, L., Protopopov, A., Chowdhury, D., & Pellman, D. (2012) · Nature · doi:10.1038/nature10802 · Cited by 1,227

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

Gibbings, D., Ciaudo, C., Erhardt, M., & Voinnet, O. (2009) · Nature Cell Biology · doi:10.1038/ncb1929 · Cited by 1,037

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

Gillooly, D. J., Morrow, I. C., Lindsay, M., Gould, R., Bryant, N. J., Gaullier, J., Parton, R. G., & Stenmark, H. (2000) · The EMBO Journal · doi:10.1093/emboj/19.17.4577 · Cited by 1,031

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

Raab, M., Gentili, M., Belly, H. D., Thiam, H. R., Vargas, P., Jiménez, A. J., Lautenschläger, F., Voituriez, R., Lennon‐Duménil, A., Manel, N., et al. (2016) · Science · doi:10.1126/science.aad7611 · Cited by 952

The lysosome as a cellular centre for signalling, metabolism and quality control

Lawrence, R. E., & Zoncu, R. (2019) · Nature Cell Biology · doi:10.1038/s41556-018-0244-7 · Cited by 920

Microautophagy of Cytosolic Proteins by Late Endosomes

Sahu, R., Kaushik, S., Clement, C. C., Cannizzo, E. S., Scharf, B., Follenzi, A., Potolicchio, I., Nieves, E., Cuervo, A. M., & Santambrogio, L. (2011) · Developmental Cell · doi:10.1016/j.devcel.2010.12.003 · Cited by 902

Escrt-III

Babst, M., Katzmann, D. J., Estepa, E. J., Meerloo, T., & Emr, S. D. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00220-4 · Cited by 865

AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

Strack, B., Calistri, A., Craig, S., Popova, E., & Göttlinger, H. G. (2003) · Cell · doi:10.1016/s0092-8674(03)00653-6 · Cited by 825

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

Skibinski, G., Parkinson, N. J., Brown, J. M., Chakrabarti, L., Lloyd, S. L., Hummerich, H., Nielsen, J. E., Hodges, J. R., Spillantini, M. G., Thusgaard, T., et al. (2005) · Nature Genetics · doi:10.1038/ng1609 · Cited by 822

Molecular mechanism of multivesicular body biogenesis by ESCRT complexes

Wollert, T., & Hurley, J. H. (2010) · Nature · doi:10.1038/nature08849 · Cited by 804

Multivesicular Endosome Biogenesis in the Absence of ESCRTs

Stuffers, S., Wegner, C. S., Stenmark, H., & Brech, A. (2009) · Traffic · doi:10.1111/j.1600-0854.2009.00920.x · Cited by 791

The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

Babst, M., Wendland, B., Estepa, E. J., & Emr, S. D. (1998) · The EMBO Journal · doi:10.1093/emboj/17.11.2982 · Cited by 770

ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation

Rühl, S., Shkarina, K., Demarco, B., Heilig, R., Santos, J. C., & Brož, P. (2018) · Science · doi:10.1126/science.aar7607 · Cited by 770

Parallels Between Cytokinesis and Retroviral Budding: A Role for the ESCRT Machinery

Carlton, J. G., & Martin-Serrano, J. (2007) · Science · doi:10.1126/science.1143422 · Cited by 764

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

Nabhan, J. F., Hu, R., Oh, R. S., Cohen, S. N., & Lu, Q. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200448109 · Cited by 763

Catastrophic nuclear envelope collapse in cancer cell micronuclei

Hatch, E. M., Fischer, A. H., Deerinck, T. J., & Hetzer, M. W. (2013) · Cell · doi:10.1016/j.cell.2013.06.007 · Cited by 741

Modification of intracellular membrane structures for virus replication

Miller, S., & Krijnse‐Locker, J. (2008) · Nature Reviews Microbiology · doi:10.1038/nrmicro1890 · Cited by 724

Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

Morita, E., Sandrin, V., Chung, H., Morham, S. G., Gygi, S. P., Rodesch, C. K., & Sundquist, W. I. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601850 · Cited by 724

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

Martin-Serrano, J., Zang, T., & Bieniasz, P. D. (2001) · Nature Medicine · doi:10.1038/nm1201-1313 · Cited by 710

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

Gong, Y.-N., Guy, C., Olauson, H., Becker, J. U., Yang, M., Fitzgerald, P., Linkermann, A., & Green, D. R. (2017) · Cell · doi:10.1016/j.cell.2017.03.020 · Cited by 689

ESCRTs are everywhere

Hurley, J. H. (2015) · The EMBO Journal · doi:10.15252/embj.201592484 · Cited by 686

ESCRT Machinery Is Required for Plasma Membrane Repair

Jiménez, A. J., Maiuri, P., Lafaurie-Janvore, J., Divoux, S., Piel, M., & Perez, F. (2014) · Science · doi:10.1126/science.1247136 · Cited by 683

Chromothripsis and Kataegis Induced by Telomere Crisis

Maciejowski, J., Li, Y., Bosco, N., Campbell, P. J., & de Lange, T. (2015) · Cell · doi:10.1016/j.cell.2015.11.054 · Cited by 675

Endosome-Associated Complex, ESCRT-II, Recruits Transport Machinery for Protein Sorting at the Multivesicular Body

Babst, M., Katzmann, D. J., Snyder, W. B., Wendland, B., & Emr, S. D. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00219-8 · Cited by 662

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Maejima, I., Takahashi, A., Omori, H., Kimura, T., Takabatake, Y., Saitoh, T., Yamamoto, A., Hamasaki, M., Noda, T., Isaka, Y., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.171 · Cited by 642

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

Steigemann, P., Wurzenberger, C., Schmitz, M. H. A., Held, M., Guizetti, J., Maar, S., & Gerlich, D. W. (2009) · Cell · doi:10.1016/j.cell.2008.12.020 · Cited by 638

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

Filimonenko, M., Stuffers, S., Raiborg, C., Yamamoto, A., Malerød, L., Fisher, E. M. C., Isaacs, A., Brech, A., Stenmark, H., & Simonsen, A. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200702115 · Cited by 626

Regulation of Clathrin-Mediated Endocytosis

Mettlen, M., Chen, P.-H., Srinivasan, S., Danuser, G., & Schmid, S. L. (2018) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-012644 · Cited by 614

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55 Gag

VerPlank, L., Bouamr, F., LaGrassa, T. J., Agresta, B., Kikonyogo, A., Leis, J., & Carter, C. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.131059198 · Cited by 584

Triggered recruitment of ESCRT machinery promotes endolysosomal repair

Skowyra, M. L., Schlesinger, P. H., Naismith, T. V., & Hanson, P. I. (2018) · Science · doi:10.1126/science.aar5078 · Cited by 578

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells.

D'Angelo, M. A., Raices, M., Panowski, S. H., & Hetzer, M. W. (2009) · Cell · doi:10.1016/j.cell.2008.11.037 · Cited by 565

Virus budding and the ESCRT pathway

Votteler, J., & Sundquist, W. I. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.08.012 · Cited by 547

pH-dependent regulation of lysosomal calcium in macrophages

Christensen, K., Myers, J. T., & Swanson, J. A. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.3.599 · Cited by 537

Cortical Constriction During Abscission Involves Helices of ESCRT-III–Dependent Filaments

Guizetti, J., Schermelleh, L., Mäntler, J., Maar, S., Poser, I., Leonhardt, H., Müller‐Reichert, T., & Gerlich, D. W. (2011) · Science · doi:10.1126/science.1201847 · Cited by 498

ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

Radulovic, M., Schink, K. O., Wenzel, E. M., Nähse, V., Bongiovanni, A., Lafont, F., & Stenmark, H. (2018) · The EMBO Journal · doi:10.15252/embj.201899753 · Cited by 496

Orchestrating nuclear envelope disassembly and reassembly during mitosis

Güttinger, S., Laurell, E., & Kutay, U. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2641 · Cited by 489

Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

Christ, L., Raiborg, C., Wenzel, E. M., Campsteijn, C., & Stenmark, H. (2016) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2016.08.016 · Cited by 474

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

Bache, K. G., Brech, A., Mehlum, A., & Stenmark, H. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302131 · Cited by 465

Vps27 recruits ESCRT machinery to endosomes during MVB sorting

Katzmann, D. J., Stefan, C. J., Babst, M., & Emr, S. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302136 · Cited by 455

Herpesviruses remodel host membranes for virus egress

Johnson, D. C., & Baines, J. D. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2559 · Cited by 451

Reverse-topology membrane scission by the ESCRT proteins

Schöneberg, J., Lee, I., Iwasa, J., & Hurley, J. H. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.121 · Cited by 443

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

Hanson, P. I., Roth, R., Lin, Y., & Heuser, J. E. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200707031 · Cited by 427

Hrs recruits clathrin to early endosomes

Raiborg, C., Bache, K. G., Mehlum, A., Stang, E., & Stenmark, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.5008 · Cited by 403

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

Elia, N., Sougrat, R., Spurlin, T. A., Hurley, J. H., & Lippincott‐Schwartz, J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102714108 · Cited by 403

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

Vietri, M., Schink, K. O., Campsteijn, C., Wegner, C. S., Schultz, S. W., Christ, L., Thoresen, S. B., Brech, A., Raiborg, C., & Stenmark, H. (2015) · Nature · doi:10.1038/nature14408 · Cited by 393

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Takahashi, Y., He, H., Tang, Z., Hattori, T., Liu, Y., Young, M. M., Serfass, J. M., Chen, L., Gebru, M., Chen, C., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05254-w · Cited by 381

A Role for the ESCRT System in Cell Division in Archaea

Samson, R. Y., Obita, T., Freund, S. M. V., Williams, R. L., & Bell, S. D. (2008) · Science · doi:10.1126/science.1165322 · Cited by 379

Mechanism of Ca2+-triggered ESCRT assembly and regulation of cell membrane repair

Scheffer, L., Sreetama, S. C., Sharma, N., Medikayala, S., Brown, K. J., Defour, A., & Jaiswal, J. K. (2014) · Nature Communications · doi:10.1038/ncomms6646 · Cited by 372

ESCRT-III controls nuclear envelope reformation

Olmos, Y., Hodgson, L. R., Mantell, J., Verkade, P., & Carlton, J. G. (2015) · Nature · doi:10.1038/nature14503 · Cited by 370

ESCRTs and Fab1 Regulate Distinct Steps of Autophagy

Rusten, T. E., Vaccari, T., Lindmo, K., Rodahl, L. M., Nezis, I. P., Sem-Jacobsen, C., Wendler, F., Vincent, J., Brech, A., Bilder, D. H., et al. (2007) · Current Biology · doi:10.1016/j.cub.2007.09.032 · Cited by 355

Ordered Assembly of the ESCRT-III Complex on Endosomes Is Required to Sequester Cargo during MVB Formation

Teis, D., Saksena, S., & Emr, S. D. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.08.013 · Cited by 345

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Study, A. C., Pharoah, P. D. P., Australian Ovarian Cancer Study Group, Tsai, Y.-Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M. A., Fridley, B. L., et al. (2013) · Nature Genetics · doi:10.1038/ng.2564 · Cited by 344

Damage control: cellular mechanisms of plasma membrane repair

Andrews, N. W., de Almeida, P. E., & Corrotte, M. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2014.07.008 · Cited by 340

Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation

Chiaruttini, N., Redondo‐Morata, L., Colom, A., Humbert, F., Lenz, M., Scheuring, S., & Roux, A. (2015) · Cell · doi:10.1016/j.cell.2015.10.017 · Cited by 338

ESCRT-III recognition by VPS4 ATPases

Stuchell‐Brereton, M. D., Skalicky, J. J., Kieffer, C., Karren, M. A., Ghaffarian, S., & Sundquist, W. I. (2007) · Nature · doi:10.1038/nature06172 · Cited by 334

ESCRT-III Governs the Aurora B–Mediated Abscission Checkpoint Through CHMP4C

Carlton, J. G., Caballe, A., Agromayor, M., Kloc, M., & Martin‐Serrano, J. (2012) · Science · doi:10.1126/science.1217180 · Cited by 333

ALIX and the multivesicular endosome: ALIX in Wonderland

Bissig, C., & Gruenberg, J. (2014) · Trends in Cell Biology · doi:10.1016/j.tcb.2013.10.009 · Cited by 323

Regulation of ubiquitin-binding proteins by monoubiquitination

Hoeller, D., Crosetto, N., Blagoev, B., Raiborg, C., Tikkanen, R., Wagner, S., Kowanetz, K., Breitling, R., Mann, M., Stenmark, H., et al. (2006) · Nature Cell Biology · doi:10.1038/ncb1354 · Cited by 320

FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes

Raiborg, C., Bremnes, B., Mehlum, A., Gillooly, D. J., D’Arrigo, A., Stang, E., & Stenmark, H. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.12.2255 · Cited by 319

Structural and Biochemical Studies of ALIX/AIP1 and Its Role in Retrovirus Budding

Fisher, R. D., Chung, H.-Y., Zhai, Q., Robinson, H., Sundquist, W. I., & Hill, C. P. (2007) · Cell · doi:10.1016/j.cell.2007.01.035 · Cited by 315

Functional Reconstitution of ESCRT-III Assembly and Disassembly

Saksena, S., Wahlman, J., Teis, D., Johnson, A. E., & Emr, S. D. (2009) · Cell · doi:10.1016/j.cell.2008.11.013 · Cited by 312

The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage

Norden, C., Mendoza, M., Dobbelaere, J., Kotwaliwale, C. V., Biggins, S., & Barral, Y. (2006) · Cell · doi:10.1016/j.cell.2006.01.045 · Cited by 304

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

Lu, Q., Hope, L. W., Brasch, M., Reinhard, C., & Cohen, S. N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0932599100 · Cited by 301

The Doa4 Deubiquitinating Enzyme Is Functionally Linked to the Vacuolar Protein-sorting and Endocytic Pathways

Amerik, A. Y., Nowak, J. A., Swaminathan, S., & Hochstrasser, M. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.10.3365 · Cited by 298

Cytokinetic Abscission: Molecular Mechanisms and Temporal Control

Mierzwa, B. E., & Gerlich, D. W. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.11.006 · Cited by 295

Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy

Mejlvang, J., Olsvik, H. L., Svenning, S., Bruun, J., Abudu, Y. P., Larsen, K. B., Brech, A., Hansen, T. E., Brenne, H. B., Hansen, T., et al. (2018) · The Journal of Cell Biology · doi:10.1083/jcb.201711002 · Cited by 292

STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes

Bache, K. G., Raiborg, C., Mehlum, A., & Stenmark, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210843200 · Cited by 286

Structure and membrane remodeling activity of ESCRT-III helical polymers

McCullough, J., Clippinger, A. K., Talledge, N., Skowyra, M. L., Saunders, M. G., Naismith, T. V., Colf, L. A., Afonine, P. V., Arthur, C. P., Sundquist, W. I., et al. (2015) · Science · doi:10.1126/science.aad8305 · Cited by 279

Cytokinesis defects and cancer

Lens, S. M. A., & Medema, R. H. (2018) · Nature reviews. Cancer · doi:10.1038/s41568-018-0084-6 · Cited by 276

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

Yang, D. J., Rismanchi, N., Renvoisé, B., Lippincott‐Schwartz, J., Blackstone, C. D., & Hurley, J. H. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1512 · Cited by 270

Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55

Lee, H. H., Elia, N., Ghirlando, R., Lippincott‐Schwartz, J., & Hurley, J. H. (2008) · Science · doi:10.1126/science.1162042 · Cited by 262

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

Connell, J. W., Lindon, C., Luzio, J. P., & Reid, E. (2008) · Traffic · doi:10.1111/j.1600-0854.2008.00847.x · Cited by 258

HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein

Pornillos, O., Higginson, D. S., Stray, K. M., Fisher, R. D., Garrus, J. E., Payne, M., He, G.-P., Wang, H. E., Morham, S. G., & Sundquist, W. I. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200302138 · Cited by 258

Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis

Mierzwa, B. E., Chiaruttini, N., Redondo‐Morata, L., von Filseck, J. M., König, J., Larios, J., Poser, I., Müller‐Reichert, T., Scheuring, S., Roux, A., et al. (2017) · Nature Cell Biology · doi:10.1038/ncb3559 · Cited by 254

The Endosomal Sorting Complex ESCRT-II Mediates the Assembly and Architecture of ESCRT-III Helices

Henne, W. M., Buchkovich, N. J., Zhao, Y., & Emr, S. D. (2012) · Cell · doi:10.1016/j.cell.2012.08.039 · Cited by 247

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

Carlton, J. G., Agromayor, M., & Martin‐Serrano, J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802008105 · Cited by 245

Cep55, a Microtubule-bundling Protein, Associates with Centralspindlin to Control the Midbody Integrity and Cell Abscission during Cytokinesis

Zhao, W.-M., Seki, A., & Fang, G. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e06-01-0015 · Cited by 244

ALIX-CHMP4 interactions in the human ESCRT pathway

McCullough, J., Fisher, R. D., Whitby, F. G., Sundquist, W. I., & Hill, C. P. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801567105 · Cited by 242

ESCRT-III protein requirements for HIV-1 budding

Morita, E., Sandrin, V., McCullough, J., Katsuyama, A., Baci Hamilton, I., & Sundquist, W. I. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.02.004 · Cited by 242

Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly

Haraguchi, T., Kojidani, T., Koujin, T., Shimi, T., Osakada, H., Mori, C., Yamamoto, A., & Hiraoka, Y. (2008) · Journal of Cell Science · doi:10.1242/jcs.033597 · Cited by 235

Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy

Papadopoulos, C., & Meyer, H. (2017) · Current Biology · doi:10.1016/j.cub.2017.11.012 · Cited by 230

Surveillance of Nuclear Pore Complex Assembly by ESCRT-III/Vps4

Webster, B. M., Colombi, P., Jäger, J., & Lusk, C. P. (2014) · Cell · doi:10.1016/j.cell.2014.09.012 · Cited by 228

ESCRT-mediated phagophore sealing during mitophagy

Zhen, Y., Spangenberg, H., Munson, M. J., Brech, A., Schink, K. O., Tan, K.-W., Sørensen, V., Wenzel, E. M., Radulovic, M., Engedal, N., et al. (2020) · Autophagy · doi:10.1080/15548627.2019.1639301 · Cited by 209

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Chang, C.-L., Weigel, A. V., Ioannou, M. S., Pasolli, H. A., Xu, C. S., Peale, D. R., Shtengel, G., Freeman, M., Hess, H. F., Blackstone, C., et al. (2019) · Journal of Cell Biology · doi:10.1083/jcb.201902061 · Cited by 206

Live-cell visualization of dynamics of HIV budding site interactions with an ESCRT component

Baumgärtel, V., Ivanchenko, S. V., Dupont, A., Sergeev, M., Wiseman, P. W., Kräusslich, H., Bräuchle, C., Müller, B., & Lamb, D. C. (2011) · Nature Cell Biology · doi:10.1038/ncb2215 · Cited by 205

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells

Gu, M., LaJoie, D., Chen, O. S., von Appen, A., Ladinsky, M. S., Redd, M. J., Nikolova, L. S., Björkman, P. J., Sundquist, W. I., Ullman, K. S., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1613916114 · Cited by 205

Distribution of ESCRT Machinery at HIV Assembly Sites Reveals Virus Scaffolding of ESCRT Subunits

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A Unique Role for the Host ESCRT Proteins in Replication of Tomato bushy stunt virus

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Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission

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An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

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Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions

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p53 Accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101

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Essential Role of hIST1 in Cytokinesis

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Torsin Mediates Primary Envelopment of Large Ribonucleoprotein Granules at the Nuclear Envelope

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The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis

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UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting

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CART: An Hrs/Actinin-4/BERP/Myosin V Protein Complex Required for Efficient Receptor Recycling

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The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

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The ESCRT Machinery Is Recruited by the Viral BFRF1 Protein to the Nucleus-Associated Membrane for the Maturation of Epstein-Barr Virus

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Molecular and Structural Basis of ESCRT-III Recruitment to Membranes during Archaeal Cell Division

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Noncanonical Role for the Host Vps4 AAA+ ATPase ESCRT Protein in the Formation of Tomato Bushy Stunt Virus Replicase

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Temporal and spatial organization of ESCRT protein recruitment during HIV-1 budding

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Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation

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Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission

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Breaching the nuclear envelope in development and disease

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An ESCRT module is required for neuron pruning

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Structural and Functional Organization of the ESCRT-I Trafficking Complex

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Unique Requirement for ESCRT Factors in Flavivirus Particle Formation on the Endoplasmic Reticulum

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An ESCRT-LEM protein surveillance system is poised to directly monitor the nuclear envelope and nuclear transport system

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Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response

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Annexin A7 is required for ESCRT III-mediated plasma membrane repair

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Host ESCRT Proteins Are Required for Bromovirus RNA Replication Compartment Assembly and Function

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Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells

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Growing functions of the ESCRT machinery in cell biology and viral replication

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The Yeast Alix Homolog Bro1 Functions as a Ubiquitin Receptor for Protein Sorting into Multivesicular Endosomes

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Endocytic Pathways Downregulate the L1-type Cell Adhesion Molecule Neuroglian to Promote Dendrite Pruning in Drosophila

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The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting

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Abscission Is Regulated by the ESCRT-III Protein Shrub in Drosophila Germline Stem Cells

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ESCRT-III is required for scissioning new peroxisomes from the endoplasmic reticulum

Mast, F. D., Herricks, T., Strehler, K. M., Miller, L. R., Saleem, R. A., Rachubinski, R. A., & Aitchison, J. D. (2018) · The Journal of Cell Biology · doi:10.1083/jcb.201706044 · Cited by 70

ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission

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ESCRT-III/Vps4 Controls Heterochromatin-Nuclear Envelope Attachments

Pieper, G. H., Sprenger, S., Teis, D., & Oliferenko, S. (2020) · Developmental Cell · doi:10.1016/j.devcel.2020.01.028 · Cited by 69

ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo

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CC2D1A Is a Regulator of ESCRT-III CHMP4B

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Role of Viral RNA and Co-opted Cellular ESCRT-I and ESCRT-III Factors in Formation of Tombusvirus Spherules Harboring the Tombusvirus Replicase

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Association of CHMP4B and autophagy with micronuclei: implications for cataract formation

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HRS-WASH axis governs actin-mediated endosomal recycling and cell invasion

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Alterations of the Coxiella burnetii Replicative Vacuole Membrane Integrity and Interplay with the Autophagy Pathway

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AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway

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Dynein pulling forces counteract lamin-mediated nuclear stability during nuclear envelope repair

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The Multifunctional Ebola Virus VP40 Matrix Protein is a Promising Therapeutic Target

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The RIF1-PP1 Axis Controls Abscission Timing in Human Cells

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Induction of autophagy in ESCRT mutants is an adaptive response for cell survival in C. elegans

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ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y1 Purinergic Receptor via a YPX3L Motif

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Inhibition of ESCRT-II–CHMP6 interactions impedes cytokinetic abscission and leads to cell death

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Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101

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Functional interplay between a virus and the ESCRT machinery in Archaea

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Loss of Nuclear Envelope Integrity in Aging and Disease

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Evidence for a Nonendosomal Function of the Saccharomyces cerevisiae ESCRT-III-Like Protein Chm7

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Capping protein regulates actin dynamics during cytokinetic midbody maturation

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A Unique N-Terminal Sequence in the Carnation Italian ringspot virus p36 Replicase-Associated Protein Interacts with the Host Cell ESCRT-I Component Vps23

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Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis

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The Ubiquitin Ligase Itch and Ubiquitination Regulate BFRF1-Mediated Nuclear Envelope Modification for Epstein-Barr Virus Maturation

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Exosomes as a new frontier of cancer liquid biopsy

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Mechanisms governing autophagosome biogenesis

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Exosomes as mediators of intercellular crosstalk in metabolism

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Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer

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Machinery, regulation and pathophysiological implications of autophagosome maturation

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Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery

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ESCRT Is a Great Sealer: Non-Endosomal Function of the ESCRT Machinery in Membrane Repair and Autophagy

Isono, E. (2021) · Plant and Cell Physiology · doi:10.1093/pcp/pcab045 · Cited by 47

ESCRTs in membrane sealing

Radulovic, M., & Stenmark, H. (2018) · Biochemical Society Transactions · doi:10.1042/bst20170435 · Cited by 44

ESCRT‐III and Vps4: a dynamic multipurpose tool for membrane budding and scission

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Membrane budding and scission by the ESCRT machinery: it's all in the neck

Hurley, J. H., & Hanson, P. I. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2937 · Cited by 793