NAD+ homeostasis in health and disease

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice

Geisler, S., Huang, S. X., Strickland, A., Doan, R. A., Summers, D. W., Mao, X., Park, J., DiAntonio, A., & Milbrandt, J. (2019) · Journal of Experimental Medicine · doi:10.1084/jem.20181040 · Cited by 145

Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD+ Recycling

Kim, W., Deik, A., González, C., Gonzalez, M. E., Fu, F., Ferrari, M., Churchhouse, C. L., Florez, J. C., Jacobs, S. B. R., Clish, C. B., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2018.12.023 · Cited by 144

A continuous microplate assay for sirtuins and nicotinamide-producing enzymes

Smith, B. C., Hallows, W. C., & Denu, J. M. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.07.019 · Cited by 143

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

Davila, A., Liu, L., Chellappa, K., Redpath, P., Nakamaru-Ogiso, E., Paolella, L. M., Zhang, Z., Migaud, M. E., Rabinowitz, J. D., & Baur, J. A. (2018) · eLife · doi:10.7554/elife.33246 · Cited by 142

Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans

van de Weijer, T., Phielix, E., Bilet, L., Williams, E. G., Ropelle, E. R., Bierwagen, A., Livingstone, R., Nowotny, P., Sparks, L. M., Paglialunga, S., et al. (2015) · Diabetes · doi:10.2337/db14-0667 · Cited by 139

Identification of NAD + capped mRNAs in Saccharomyces cerevisiae

Walters, R. W., Matheny, T., Mizoue, L. S., Rao, B. S., Muhlrad, D., & Parker, R. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1619369114 · Cited by 139

NAD + supplementation rejuvenates aged gut adult stem cells

Igarashi, M., Miura, M., Williams, E., Jaksch, F., Kadowaki, T., Yamauchi, T., & Guarente, L. (2019) · Aging Cell · doi:10.1111/acel.12935 · Cited by 138

Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis

Schweiger, M., Hennig, K., Lerner, F., Niere, M., Hirsch‐Kauffmann, M., Specht, T., Weise, C., Oei, S. L., & Ziegler, M. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02180-9 · Cited by 137

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

Sallin, O., Reymond, L., Gondrand, C., Raith, F., Koch, B., & Johnsson, K. (2018) · eLife · doi:10.7554/elife.32638 · Cited by 137

Structural characterization of a human cytosolic NMN/NaMN adenylyltransferase and implication in human NAD biosynthesis

Zhang, X., Kurnasov, O. V., Karthikeyan, S., Grishin, N. V., Osterman, A. L., & Zhang, H. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300073200 · Cited by 136

The ALD6 Gene Product Is Indispensable for Providing NADPH in Yeast Cells Lacking Glucose-6-phosphate Dehydrogenase Activity

Grabowska, D., & Chełstowska, A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m210076200 · Cited by 136

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes

Yang, S. J., Choi, J. M., Kim, L., Park, S. E., Rhee, E., Lee, W., Oh, K. W., Park, S. W., & Park, C.-Y. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.09.004 · Cited by 135

SARM1-specific motifs in the TIR domain enable NAD + loss and regulate injury-induced SARM1 activation

Summers, D. W., Gibson, D. A., DiAntonio, A., & Milbrandt, J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1601506113 · Cited by 133

Essential role for IL-6 in postresuscitation inflammation in hemorrhagic shock

Meng, Z. H., Dyer, K., Billiar, T. R., & Tweardy, D. J. (2001) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2001.280.2.c343 · Cited by 131

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

Jesús‐Cortés, H. D., Xu, P., Drawbridge, J., Estill, S. J., Huntington, P. J., Tran, S., Britt, J. K., Tesla, R., Morlock, L., Naidoo, J., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213956109 · Cited by 130

Nicotinamide phosphoribosyltransferase imparts human endothelial cells with extended replicative lifespan and enhanced angiogenic capacity in a high glucose environment

Borradaile, N. M., & Pickering, J. G. (2009) · Aging Cell · doi:10.1111/j.1474-9726.2009.00453.x · Cited by 129

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Tesla, R., Wolf, H. P., Xu, P., Drawbridge, J., Estill, S. J., Huntington, P., McDaniel, L., Knobbe, W., Burket, A., Tran, S., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213960109 · Cited by 129

A chemical screen for biological small molecule–RNA conjugates reveals CoA-linked RNA

Kowtoniuk, W. E., Shen, Y., Heemstra, J. M., Agarwal, I., & Liu, D. R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900528106 · Cited by 129

Identification of a novel human nicotinamide mononucleotide adenylyltransferase

Raffaelli, N., Sorci, L., Amici, A., Emanuelli, M., Mazzola, F., & Magni, G. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02285-4 · Cited by 127

Muscle-Specific SIRT1 Gain-of-Function Increases Slow-Twitch Fibers and Ameliorates Pathophysiology in a Mouse Model of Duchenne Muscular Dystrophy

Chalkiadaki, A., Igarashi, M., Nasamu, A. S., Knezevic, J., & Guarente, L. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004490 · Cited by 126

Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis

Pittelli, M. G., Felici, R., Pitozzi, V., Giovannelli, L., Bigagli, E., Cialdai, F., Romano, G., Moroni, F., & Chiarugi, A. (2011) · Molecular Pharmacology · doi:10.1124/mol.111.073916 · Cited by 125

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

Fletcher, R. S., Ratajczak, J., Doig, C. L., Oakey, L. A., Callingham, R., Xavier, G. D. S., Garten, A., Elhassan, Y., Redpath, P., Migaud, M. E., et al. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.05.011 · Cited by 125

Poly (ADP-Ribose) Polymerase-1 Is a Key Mediator of Liver Inflammation and Fibrosis

Mukhopadhyay, P., Rajesh, M., Cao, Z., Horváth, B., Park, O., Wang, H., Erdélyi, K., Holovac, E., Wang, Y., Liaudet, L., et al. (2013) · Hepatology · doi:10.1002/hep.26763 · Cited by 125

[39] Protein phosphatase-2C from rabbit skeletal muscle and liver: An Mg2+-dependent enzyme

McGowan, C. H., & Cohen, P. (1988) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(88)59041-9 · Cited by 124

P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury

Yin, T. C., Britt, J. K., Jesús‐Cortés, H. D., Lü, Y., Genova, R. M., Khan, M. Z., Voorhees, J. R., Shao, J., Katzman, A. C., Huntington, P. J., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.030 · Cited by 124

Studies on the Biosynthesis of Nicotinamide Adenine Dinucleotide

Ijichi, H., Ichiyama, A., & Hayaishi, O. (1966) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99829-7 · Cited by 121

The Reaction Mechanism for CD38. A Single Intermediate Is Responsible for Cyclization, Hydrolysis, and Base-Exchange Chemistries

Sauve, A. A., Munshi, C. B., Lee, H. C., & Schramm, V. L. (1998) · Biochemistry · doi:10.1021/bi981248s · Cited by 120

Axonal degeneration as a therapeutic target in the CNS

Lingor, P., Koch, J. C., Tönges, L., & Bähr, M. (2012) · Cell and Tissue Research · doi:10.1007/s00441-012-1362-3 · Cited by 119

The Cholesterol Lowering Atherosclerosis Study (CLAS): Design, methods, and baseline results

Blankenhorn, D. H., Johnson, R. L., Nessim, S., Azen, S. P., Sanmarco, M. E., & Selzer, R. H. (1987) · Controlled Clinical Trials · doi:10.1016/0197-2456(87)90156-5 · Cited by 118

The early IL‐6 and IL‐10 response in trauma is correlated with injury severity and mortality

Stensballe, J., Christiansen, M., Tønnesen, E., Espersen, K., Lippert, F. K., & Rasmussen, L. S. (2009) · Acta Anaesthesiologica Scandinavica · doi:10.1111/j.1399-6576.2008.01801.x · Cited by 116

Syntheses of Nicotinamide Riboside and Derivatives: Effective Agents for Increasing Nicotinamide Adenine Dinucleotide Concentrations in Mammalian Cells

Yang, T., Chan, N. Y., & Sauve, A. A. (2007) · Journal of Medicinal Chemistry · doi:10.1021/jm701001c · Cited by 115

Peripheral distribution of kynurenine metabolites and activity of kynurenine pathway enzymes in renal failure.

Pawlak, D., Tankiewicz‐Kwedlo, A., Matys, T., & Buczko, W. (2003) · PubMed · Cited by 113

Dihydronicotinamide riboside is a potent NAD+ concentration enhancer in vitro and in vivo

Yang, Y. J., Mohammed, N. A. K., Zhang, N., & Sauve, A. A. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.005772 · Cited by 113

The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity

Ugur, S., Ulu, R., Doğukan, A., Gürel, A., Yiğit, İ. P., Gözel, N., Aygen, B., & İlhan, A. (2015) · Renal Failure · doi:10.3109/0886022x.2014.986005 · Cited by 113

Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH

Madsen, A. S., Andersen, C. D., Daoud, M., Anderson, K. A., Laursen, J. S., Chakladar, S., Huynh, F. K., Colaço, A. R., Backos, D. S., Fristrup, P., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.668699 · Cited by 111

Studies of the Dietary Habits, Food Consumption and Nutrient Intakes of Adolescents and Young Adults

Bull, N. L. (2015) · World review of nutrition and dietetics · doi:10.1159/000416396 · Cited by 102

Large Supplements of Nicotinic Acid and Nicotinamide Increase Tissue NAD+ and Poly(ADP-Ribose) Levels but Do Not Affect Diethylnitrosamine-Induced Altered Hepatic Foci in Fischer-344 Rats

Jackson, T. M., Rawling, J. M., Roebuck, B. D., & Kirkland, J. B. (1995) · Journal of Nutrition · doi:10.1093/jn/125.6.1455 · Cited by 102

Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling

Li, Z., Xu, K., Zhang, N., Amador, G. O., Wang, Y., Zhao, S., Li, L., Qiu, Y., & Wang, Z. (2018) · Kidney International · doi:10.1016/j.kint.2017.10.021 · Cited by 95

Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome

Mauvoisin, D., Atger, F., Dayon, L., Galindo, A. N., Wang, J., Martín, E., Silva, L. D., Montoliu, I., Collino, S., Martin, F., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.07.065 · Cited by 94

The association of elevated reactive oxygen species levels from neutrophils with low-grade inflammation in the elderly

Ogawa, K., Suzuki, K., Okutsu, M., Yamazaki, K., & Shinkai, S. (2008) · Immunity & Ageing · doi:10.1186/1742-4933-5-13 · Cited by 93

NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia

Zheng, C., Han, J., Xia, W., Shi, S., Liu, J., & Ying, W. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.01.007 · Cited by 92

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

de la Rubia, J. E., Drehmer, E., Platero, J. L., Benlloch, M., Caplliure-Llopis, J., Villaron-Casales, C., de Bernardo, N., AlarcÓn, J., Fuente, C., Carrera, S., et al. (2019) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2018.1536152 · Cited by 92

Lipid-Altering Efficacy and Safety of Ezetimibe/Simvastatin Coadministered With Extended-Release Niacin in Patients With Type IIa or Type IIb Hyperlipidemia

Guyton, J. R., Brown, B. G., Fazio, S., Polis, A., Tomassini, J. E., & Tershakovec, A. M. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.03.003 · Cited by 91

Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine

Riederer, M., Erwa, W., Zimmermann, R., Frank, S., & Zechner, R. (2008) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2008.09.015 · Cited by 91

Sirtuins and the circadian clock: Bridging chromatin and metabolism

Masri, S., & Sassone‐Corsi, P. (2014) · Science Signaling · doi:10.1126/scisignal.2005685 · Cited by 91

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation

Zheng, M., Cai, J., Liu, Z., Shu, S., Wang, Y., Tang, C., & Dong, Z. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14285 · Cited by 91

Highly efficient 5' capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase

Bird, J. G., Basu, U., Kuster, D., Ramachandran, A., Grudzien‐Nogalska, E., Towheed, A., Wallace, D. C., Kiledjian, M., Temiakov, D., Patel, S. S., et al. (2018) · eLife · doi:10.7554/elife.42179 · Cited by 89

Pyridin, der wasserstoffübertragende Bestandteil von Gärungsfermenten

Warburg, O. H., & Walter, C. A. (1936) · Helvetica Chimica Acta · doi:10.1002/hlca.193601901199 · Cited by 86

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Neelakantan, H., Vance, V., Wetzel, M. D., Wang, H.-Y. L., McHardy, S. F., Finnerty, C. C., Hommel, J. D., & Watowich, S. J. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.11.007 · Cited by 85

Regulation of Calcium Signaling by the Second Messenger Cyclic Adenosine Diphosphoribose (cADPR)

Guse, A. H. (2004) · Current Molecular Medicine · doi:10.2174/1566524043360771 · Cited by 84

Dysregulation of SIRT-1 in aging mice increases skeletal muscle fatigue by a PARP-1-dependent mechanism

Mohamed, J. S., Wilson, J. C., Myers, M. J., Sisson, K. J., & Alway, S. E. (2014) · Aging · doi:10.18632/aging.100696 · Cited by 83

Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells

VanLinden, M. R., Dölle, C., Pettersen, I. K. N., Kulikova, V., Niere, M., Agrimi, G., Dyrstad, S. E., Palmieri, F., Nikiforov, A. A., Tronstad, K. J., et al. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.654129 · Cited by 82

Identification of and molecular basis for sirt6 loss-of-function point mutations in cancer

Kugel, S., Feldman, J. L., Klein, M. A., Silberman, D. M., Sebastián, C., Mermel, C., Dobersch, S., Clark, A. R., Getz, G., Denu, J. M., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.022 · Cited by 81

Deficiency of Nicotinamide Mononucleotide Adenylyltransferase 3 (Nmnat3) Causes Hemolytic Anemia by Altering the Glycolytic Flow in Mature Erythrocytes

Hikosaka, K., Ikutani, M., Shito, M., Kazuma, K., Gulshan, M., Nagai, Y., Takatsu, K., Konno, K., Tobe, K., Kanno, H., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.554378 · Cited by 81

Coronary drug project: Experience with niacin

Berge, K. G., & Canner, P. L. (1991) · European Journal of Clinical Pharmacology · doi:10.1007/bf03216290 · Cited by 80

Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: Chemical and metabolic logic of acetyl-lysine modifications

Ghanta, S., Grossmann, R. E., & Brenner, C. (2013) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2013.838204 · Cited by 80

Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

Hamity, M. V., White, S. R., Walder, R. Y., Schmidt, M. S., Brenner, C., & Hammond, D. L. (2017) · Pain · doi:10.1097/j.pain.0000000000000862 · Cited by 79

Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation

Sahar, S., Nin, V., Barbosa, M. T., Chini, E. N., & Sassone-Corsi, P. (2011) · Aging · doi:10.18632/aging.100368 · Cited by 79

Tissue expression and biochemical characterization of human 2‐amino 3‐carboxymuconate 6‐semialdehyde decarboxylase, a key enzyme in tryptophan catabolism

Pucci, L., Perozzi, S., Cimadamore, F., Orsomando, G., & Raffaelli, N. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05635.x · Cited by 78

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice

Bellet, M. M., Masri, S., Astarita, G., Sassone‐Corsi, P., Fazia, M. A. D., & Servillo, G. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.737114 · Cited by 78

(−)-P7C3-S243 Protects a Rat Model of Alzheimer’s Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia

Voorhees, J. R., Remy, M. T., Cintrón-Pérez, C. J., El Rassi, E., Khan, M. Z., Dutca, L. M., Yin, T. C., McDaniel, L. N., Williams, N. S., Brat, D. J., et al. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.10.023 · Cited by 78

Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity

Dollerup, O. L., Trammell, S. A. J., Hartmann, B., Holst, J. J., Christensen, B., Møller, N., Gillum, M. P., Treebak, J. T., & Jessen, N. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2019-01081 · Cited by 77

Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment

Zhou, M., Ottenberg, G. K., Sferrazza, G. F., Hubbs, C., Fallahi, M., Rumbaugh, G., Brantley, A. F., & Lasmézas, C. I. (2015) · Brain · doi:10.1093/brain/awv002 · Cited by 77

Bacterial RNA polymerase caps RNA with various cofactors and cell wall precursors

Julius, C., & Yuzenkova, Y. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx452 · Cited by 77

Small molecule nicotinamide N‐methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Neelakantan, H., Brightwell, C. R., Graber, T. G., Maroto, R., Wang, H.-Y. L., McHardy, S. F., Papaconstantinou, J., Fry, C. S., & Watowich, S. J. (2019) · Biochemical Pharmacology · doi:10.1016/j.bcp.2019.02.008 · Cited by 76

PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis

Waldman, M., Nudelman, V., Shainberg, A., Abraham, N. G., Kornwoski, R., Aravot, D. J., Arad, M., & Hochhauser, E. (2018) · Experimental Cell Research · doi:10.1016/j.yexcr.2018.10.003 · Cited by 75

Molecular Identification of Human Glutamine- and Ammonia-dependent NAD Synthetases

Hara, N., Yamada, K., Terashima, M., Osago, H., Shimoyama, M., & Tsuchiya, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209203200 · Cited by 74

The branchial chloride pump in the goldfish Carassius auratus: relationship between Cl-/HCO3- and Cl-/Cl- exchanges and the effect of thiocyanate

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Evaluating the role of niacin in human carcinogenesis

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Maternal Nicotinamide Riboside Enhances Postpartum Weight Loss, Juvenile Offspring Development, and Neurogenesis of Adult Offspring

Ear, P. H., Chadda, A., Gumusoglu, S. B., Schmidt, M. S., Vogeler, S., Malicoat, J., Kadel, J., Moore, M. M., Migaud, M. E., Stevens, H. E., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.01.007 · Cited by 72

The suppression of rejection of Nippostrongylus brasiliensis in lactating rats: the nature of the immunological defect.

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Niacin: an old lipid drug in a new NAD+ dress

Romani, M., Hofer, D., Katsyuba, E., & Auwerx, J. H. (2019) · Journal of Lipid Research · doi:10.1194/jlr.s092007 · Cited by 72

Nmnat3 Is Dispensable in Mitochondrial NAD Level Maintenance In Vivo

Yamamoto, M., Hikosaka, K., Mahmood, A., Tobe, K., Shojaku, H., Inohara, H., & Nakagawa, T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147037 · Cited by 70

Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease

Ward, J. M., Stoyas, C. A., Switonski, P. M., Ichou, F., Fan, W., Collins, B. L., Wall, C. E., Adanyeguh, I. M., Niu, C., Sopher, B. L., et al. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.01.028 · Cited by 70

Probable mechanisms of regulation of the utilization of dietary tryptophan, nicotinamide and nicotinic acid as precursors of nicotinamide nucleotides in the rat

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A Novel Muscle-Specific β1 Integrin Binding Protein (Mibp) That Modulates Myogenic Differentiation

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NAD Blocks High Glucose Induced Mesangial Hypertrophy via Activation of the Sirtuins-AMPK-mTOR Pathway

Zhuo, L., Fu, B., Bai, X., Zhang, B., Wu, L., Cui, J., Cui, S., Ribao, W., Chen, X., & Cai, G. (2011) · Cellular Physiology and Biochemistry · doi:10.1159/000330077 · Cited by 69

Luteolinidin Protects the Postischemic Heart through CD38 Inhibition with Preservation of NAD(P)(H)

Boslett, J., Hemann, C., Zhao, Y. J., Lee, H.-C., & Zweier, J. L. (2017) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.239459 · Cited by 69

Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock

Sims, C. A., Guan, Y., Mukherjee, S., Singh, K., Botolin, P., Dávila, A., & Baur, J. A. (2018) · JCI Insight · doi:10.1172/jci.insight.120182 · Cited by 67

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase.

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Influence of Continuous Gonadotropin-Releasing Hormone (GnRH) Agonist Treatment on Luteinizing Hormone and Testosterone Secretion, the Response to GnRH, and the Testicular Response to Human Chorionic Gonadotropin in Male Rhesus Monkeys*

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NADP+ is an endogenous PARP inhibitor in DNA damage response and tumor suppression

Bian, C., Zhang, C., Luo, T., Vyas, A., Chen, S.-H., Liu, C., Kassab, M. A., Yang, Y., Kong, M., & Yu, X. (2019) · Nature Communications · doi:10.1038/s41467-019-08530-5 · Cited by 66

Treatment of Alzheimer's disease with stabilized oral nicotinamide adenine dinucleotide: a randomized, double-blind study.

Demarin, V., Podobnik, S. S., Štorga-Tomić, D., & Kay, G. (2004) · PubMed · Cited by 65

Nicotinamide Attenuates Focal Ischemic Brain Injury in Rats: With Special Reference to Changes in Nicotinamide and NAD+ Levels in Ischemic Core and Penumbra

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