Leveraging technology to personalize cognitive enhancement methods in aging
Open accessAbstract
As population aging advances at an increasing rate, efforts to help people maintain or improve cognitive function late in life are critical. Although some studies have shown promise, the question of whether cognitive training is an effective tool for improving general cognitive ability remains incompletely explored, and study results to date have been inconsistent. Most approaches to cognitive enhancement in older adults have taken a 'one size fits all' tack, as opposed to tailoring interventions to the specific needs of individuals. In this Perspective, we argue that modern technology has the potential to enable large-scale trials of public health interventions to enhance cognition in older adults in a personalized manner. Technology-based cognitive interventions that rely on closed-loop systems can be tailored to individuals in real time and have the potential for global testing, extending their reach to large and diverse populations of older adults. We propose that the future of cognitive enhancement in older adults will rely on harnessing new technologies in scientifically informed ways.
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Cognitive training through digital platforms offers exercises designed to target specific cognitive domains, such as memory, attention, and executive function, with the goal of improving overall cognitive abilities and everyday functioning.
“Cognitive training through digital platforms such as through computer programs, smartphone apps, wearables or webbased platforms offer exercises designed to target specific cognitive domains, such as memory, attention, and executive function, with the goal of improving overall cognitive abilities and everyday functioning (Ziegler et al., 2022).”
From The impact of digital technology, social media, and artificial intelligence on cognitive functions: a review (2023) · cites this paper as Ziegler et al., 2022
The sections on closed-loop video games and digital meditation describe technology-based interventions targeting attention, working memory and cognitive control; the virtual-reality section addresses long-term memory (page numbers unavailable). The paper does not establish that these exercises improve overall cognitive ability or everyday functioning, and it describes the benefits of cognitive training for older adults as ambiguous. It also does not present the full list of computer programs, apps, wearables and web platforms as interchangeable cognitive-training formats. (LLM, conf=0.84)
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- Authors
- Ziegler, D. A., Anguera, J. A., Gallen, C. L., Hsu, W.-Y., Wais, P. E., & Gazzaley, A.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Ziegler, David A.
- Venue
- Nature Aging
- Published
- 2022-06-17
- Volume
- 2
- Issue
- 6
- Pages
- 475-483
- ISSN
- 2662-8465 (ISSN-L)
- PMC
- PMC9302894
- OpenAlex
- W4283023732
- Cited by
- 50
- References
- 135
- Citations by year
- 2026: 5 · 2025: 24 · 2024: 17 · 2023: 3 · 2022: 1
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Nature Aging (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health (R01-AG076668, R34-MH100466, K99/R00-AG043557, R01-AG049424, R21-AG058896, R01-AG040333, R21-AG041071)
- Schwab Dyslexia and Cognitive Diversity Center Innovation Fund Award
- Neuroscape Network
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Abilities and Testing
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- cognitive enhancement, older adults, cognitive training, personalized interventions, technology-based interventions, closed-loop systems, real-time personalization, public health interventions, cognitive aging, large-scale trials
- MeSH terms
- Cognitive Training, Aged, Aging, Cognition, Humans, Technology
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