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Adverse effects of microplastics and oxidative stress-induced MAPK/Nrf2 pathway-mediated defense mechanisms in the marine copepod Paracyclopina nana
Open accessAbstract
Microplastic pollution causes a major concern in the marine environment due to their worldwide distribution, persistence, and adverse effects of these pollutants in the marine ecosystem. Despite its global presence, there is still a lack of information on the effect of microplastics on marine organisms at the molecular level. Herein we demonstrated ingestion and egestion of nano- (0.05 μm) and micro-sized (0.5 and 6 μm) polystyrene microbeads in the marine copepod Paracyclopina nana, and examined molecular responses to exposure to microbeads with in vivo endpoints such as growth rate and fecundity. Also, we proposed an adverse outcome pathway for microplastic exposure that covers molecular and individual levels. This study provides the first insight into the mode of action in terms of microplastic-induced oxidative stress and related signaling pathways in P. nana.
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Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Microplastics in the marine environment
Andrady, A. L. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.05.030 · Cited by 8,105
Accumulation and fragmentation of plastic debris in global environments
Barnes, D. K. A., Galgani, F., Thompson, R. C., & Barlaz, M. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0205 · Cited by 6,126
Microplastics as contaminants in the marine environment: A review
Cole, M., Lindeque, P., Halsband, C., & Galloway, T. S. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.09.025 · Cited by 6,023
Meister, A., & Anderson, M. E. (1983) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.52.070183.003431 · Cited by 5,680
Eriksen, M., Lebreton, L. C. M., Carson, H. S., Thiel, M., Moore, C. J., Borerro, J. C., Galgani, F., Ryan, P. G., & Reisser, J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111913 · Cited by 4,710
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6943 · Cited by 3,999
Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells
AshaRani, P. V., Low Kah Mun, G., Hande, M. P., & Valiyaveettil, S. (2009) · ACS Nano · doi:10.1021/nn800596w · Cited by 3,692
Plastics Recycling: Challenges and Opportunities
Hopewell, J., Dvorak, R., & Kosior, E. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0311 · Cited by 3,201
Microplastic ingestion by zooplankton
Cole, M., Lindeque, P., Fileman, E., Halsband, C., Goodhead, R., Moger, J., & Galloway, T. S. (2013) · Environmental Science & Technology · doi:10.1021/es400663f · Cited by 2,763
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
McCubrey, J. A., Steelman, L. S., Chappell, W. H., Abrams, S. L., Wong, E. W. T., Chang, F., Lehmann, B., Terrian, D. M., Milella, M., Tafuri, A., et al. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.10.001 · Cited by 2,284
Lu, Y., Zhang, Y., Deng, Y., Jiang, W., Zhao, Y., Geng, J., Ding, L., & Ren, H. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b00183 · Cited by 2,125
Synthetic polymers in the marine environment: A rapidly increasing, long-term threat
Moore, C. J. (2008) · Environmental Research · doi:10.1016/j.envres.2008.07.025 · Cited by 2,112
Lusher, A. L., McHugh, M., & Thompson, R. C. (2013) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2012.11.028 · Cited by 2,075
Ingested plastic transfers hazardous chemicals to fish and induces hepatic stress
Rochman, C. M., Hoh, E., Kurobe, T., & Teh, S. J. (2013) · Scientific Reports · doi:10.1038/srep03263 · Cited by 2,027
Size‐Dependent Cytotoxicity of Gold Nanoparticles
Pan, Y., Neuss, S., Leifert, A., Fischler, M., Wen, F., Simon, U., Schmid, G., Brandau, W., & Jahnen‐Dechent, W. (2007) · Small · doi:10.1002/smll.200700378 · Cited by 1,878
OXIDATIVE STRESS IN MARINE ENVIRONMENTS: Biochemistry and Physiological Ecology
Lesser, M. P. (2006) · Annual Review of Physiology · doi:10.1146/annurev.physiol.68.040104.110001 · Cited by 1,833
Ingestion and transfer of microplastics in the planktonic food web
Setälä, O., Fleming-Lehtinen, V., & Lehtiniemi, M. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2013.10.013 · Cited by 1,635
The present and future of microplastic pollution in the marine environment
Ivar do Sul, J. A., & Costa, M. F. (2014) · Environmental Pollution · doi:10.1016/j.envpol.2013.10.036 · Cited by 1,605
Mitogen-activated protein kinases in apoptosis regulation
Wada, T., & Penninger, J. M. (2004) · Oncogene · doi:10.1038/sj.onc.1207556 · Cited by 1,432
Size Dependent and Reactive Oxygen Species Related Nanosilver Toxicity to Nitrifying Bacteria
Choi, O., & Hu, Z. (2008) · Environmental Science & Technology · doi:10.1021/es703238h · Cited by 1,391
Cole, M., Lindeque, P., Fileman, E., Halsband, C., & Galloway, T. S. (2015) · Environmental Science & Technology · doi:10.1021/es504525u · Cited by 1,308
Jeong, C.-B., Won, E.-J., Kang, H.-M., Lee, M.-C., Hwang, D.-S., Hwang, U.-K., Zhou, B., Souissi, S., Lee, S.-J., & Lee, J.-S. (2016) · Environmental Science & Technology · doi:10.1021/acs.est.6b01441 · Cited by 1,233
Self-citationMitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways?
Son, Y., Cheong, Y.-K., Kim, N.-H., Chung, H.-T., Kang, D. G., & Pae, H.-O. (2011) · Journal of Signal Transduction · doi:10.1155/2011/792639 · Cited by 1,219
Nanoplastic Affects Growth of S. obliquus and Reproduction of D. magna
Besseling, E., Wang, B., Lürling, M., & Koelmans, A. A. (2014) · Environmental Science & Technology · doi:10.1021/es503001d · Cited by 1,138
Microplastic ingestion decreases energy reserves in marine worms
Wright, S. L., Rowe, D., Thompson, R. C., & Galloway, T. S. (2013) · Current Biology · doi:10.1016/j.cub.2013.10.068 · Cited by 1,079
Ingestion of Microplastics by Zooplankton in the Northeast Pacific Ocean
Desforges, J.-P. W., Galbraith, M., & Ross, P. S. (2015) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-015-0172-5 · Cited by 1,019
Size-Dependent Effects of Micro Polystyrene Particles in the Marine Copepod Tigriopus japonicus
Lee, K.-W., Shim, W. J., Kwon, O. Y., & Kang, J.-H. (2013) · Environmental Science & Technology · doi:10.1021/es401932b · Cited by 923
Amini, A., & Cheng, C. (2013) · Scientific Reports · doi:10.1038/srep03316 · Cited by 594
Batel, A., Linti, F., Scherer, M., Erdinger, L., & Braunbeck, T. (2016) · Environmental Toxicology and Chemistry · doi:10.1002/etc.3361 · Cited by 589
Nrf2 is essential for protection against acute pulmonary injury in mice
Chan, K., & Kan, Y. W. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.22.12731 · Cited by 574
Lusher, A. L., Hernandez-Milian, G., O'Brien, J., Berrow, S., O'Connor, I., & Officer, R. (2015) · Environmental Pollution · doi:10.1016/j.envpol.2015.01.023 · Cited by 551
Matsuzawa, A., & Ichijo, H. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2007.12.011 · Cited by 502
Origins and Biological Accumulation of Small Plastic Particles in Fur Seals from Macquarie Island
Eriksson, C., & Burton, H. (2003) · AMBIO: A Journal of the Human Environment · doi:10.1579/0044-7447-32.6.380 · Cited by 457
Li, N., Alam, J., Venkatesan, M. I., Eiguren-Fernandez, A., Schmitz, D., Di Stefano, E., Slaughter, N., Killeen, E., Wang, X., Huang, A., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.5.3467 · Cited by 456
Suhrhoff, T. J., & Scholz-Böttcher, B. M. (2016) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2015.11.054 · Cited by 453
Microplastic in a macro filter feeder: Humpback whale Megaptera novaeangliae
Besseling, E., Foekema, E. M., Van Franeker, J. A., Leopold, M. F., Kühn, S., Bravo Rebolledo, E. L., Heße, E., Mielke, L., IJzer, J., Kamminga, P., et al. (2015) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2015.04.007 · Cited by 443
Suthanthiran, M., Anderson, M. E., Sharma, V. K., & Meister, A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.9.3343 · Cited by 382
Nanoparticles can cause DNA damage across a cellular barrier
Bhabra, G., Sood, A., Fisher, B., Cartwright, L., Saunders, M., Evans, W. H., Surprenant, A., Lopez-Castejon, G., Mann, S., Davis, S. A., et al. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.313 · Cited by 381
Polystyrene Nanoparticles Perturb Lipid Membranes
Rossi, G., Barnoud, J., & Monticelli, L. (2014) · The Journal of Physical Chemistry Letters · doi:10.1021/jz402234c · Cited by 373
Raisuddin, S., Kwok, K. W. H., Leung, K. M. Y., Schlenk, D., & Lee, J.-S. (2007) · Aquatic Toxicology · doi:10.1016/j.aquatox.2007.04.005 · Cited by 373
Self-citationParadigms to assess the environmental impact of manufactured nanomaterials
Klaine, S. J., Koelmans, A. A., Horne, N., Carley, S., Handy, R. D., Kapustka, L., Nowack, B., & von der Kammer, F. (2012) · Environmental Toxicology and Chemistry · doi:10.1002/etc.733 · Cited by 371
Effect of Nanoparticles on the Cell Life Cycle
Mahmoudi, M., Azadmanesh, K., Shokrgozar, M. A., Journeay, W. S., & Laurent, S. (2011) · Chemical Reviews · doi:10.1021/cr1003166 · Cited by 352
Salvati, A., Åberg, C., dos Santos, T., Varela, J., Pinto, P., Lynch, I., & Dawson, K. A. (2011) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2011.03.005 · Cited by 333
A comparison of nanoparticle and fine particle uptake by Daphnia magna
Rosenkranz, P., Chaudhry, Q., Stone, V., & Fernandes, T. F. (2009) · Environmental Toxicology and Chemistry · doi:10.1897/08-559.1 · Cited by 331
Rios*, L. M., Jones, P. R., Moore, C., & Narayan, U. V. (2010) · Journal of Environmental Monitoring · doi:10.1039/c0em00239a · Cited by 319
Eom, H.-J., & Choi, J. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.01.028 · Cited by 249
Oxidative stress responses of Daphnia magna exposed to TiO2 nanoparticles according to size fraction
Kim, K. T., Klaine, S. J., Cho, J., Kim, S.-H., & Kim, S. D. (2010) · Science of The Total Environment · doi:10.1016/j.scitotenv.2010.01.041 · Cited by 227
The Genetic Basis of White Tigers
Xu, X., Dong, G.-X., Hu, X.-S., Miao, L., Zhang, X.-L., Zhang, D.-L., Yang, H.-D., Zhang, T.-Y., Zou, Z.-T., Zhang, T.-T., et al. (2013) · Current Biology · doi:10.1016/j.cub.2013.04.054 · Cited by 212
Regulation of Nrf2 Transactivation Domain Activity
Shen, G., Hebbar, V., Nair, S., Xu, C., Li, W., Lin, W., Keum, Y.-S., Han, J., Gallo, M. A., & Kong, A.-N. T. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m401368200 · Cited by 194
Self-citationSato, A., Okada, M., Shibuya, K., Watanabe, E., Seino, S., Narita, Y., Shibui, S., Kayama, T., & Kitanaka, C. (2013) · Stem Cell Research · doi:10.1016/j.scr.2013.09.012 · Cited by 161
Redox State Changes in Density-Dependent Regulation of Proliferation
Hutter, D., Till, B. G., & Greene, J. J. (1997) · Experimental Cell Research · doi:10.1006/excr.1997.3527 · Cited by 150
Wang, X., Liu, J.-Z., Hu, J. X., Wu, H., Li, Y., Chen, H., Bai, H., & Hai, C.-X. (2011) · Free Radical Biology & Medicine · doi:10.1016/j.freeradbiomed.2011.04.019 · Cited by 146
Rhee, J., Yu, I. T., Kim, B., Jeong, C., Lee, K., Kim, M.-J., Lee, S., Park, G. S., & Lee, J. (2013) · Aquatic Toxicology · doi:10.1016/j.aquatox.2013.02.013 · Cited by 108
Self-citationEffects of diets on the growth of the brackish water cyclopoid copepod Paracyclopina nana Smirnov
Lee, K. W., Park, H. G., Lee, S., & Kang, H. (2006) · Aquaculture · doi:10.1016/j.aquaculture.2006.01.015 · Cited by 87
Self-citationKim, B., Rhee, J., Lee, K., Kim, M., Shin, K., Lee, S., Lee, Y.-M., & Lee, J. (2014) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2014.08.003 · Cited by 72
Self-citationDahms, H.-U., Won, E., Kim, H.-S., Han, J., Park, H. G., Souissi, S., Raisuddin, S., & Lee, J. (2016) · Aquatic Toxicology · doi:10.1016/j.aquatox.2016.10.013 · Cited by 50
Self-citationUptake of latex beads as size-model for food of planktonic rotifers
Ronneberger, D. (1998) · Hydrobiologia · doi:10.1023/a:1017046711821 · Cited by 21
Uptake of latex beads as size-model for food of planktonic rotifers
Ronneberger, D. (1998) · Springer eBooks · doi:10.1007/978-94-011-4782-8_57 · Cited by 19
de Souza-Bastos, L. R., Páscoa, M. I., Freire, C. A., & Wilson, J. M. (2013) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2013.09.009 · Cited by 13
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Metadata
- Authors
- Jeong, C.-B., Kang, H.-M., Lee, M.-C., Kim, D.-H., Han, J., Hwang, D.-S., Souissi, S., Lee, S.-J., Shin, K.-H., Park, H. G., & Lee, J.-S.
- Venue
- Scientific Reports
- Published
- 2017-01-24
- Volume
- 7
- Issue
- 1
- Pages
- 41323-41323
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2580899680
- Cited by
- 585
- References
- 60
- FWCI
- 17.61
- Type
- journal article
- Language
- en
- Open access
- gold
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