Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer ( Brachionus koreanus )

Jeong, Chang-Bum; Won, Eun-Ji; Kang, Hye-Min; Lee, Min-Chul; Hwang, Dae-Sik; Hwang, Un-Ki; Zhou, Bingsheng; Souissi, Sami; Lee, Su-Jae; Lee, Jae-Seong

doi:10.1021/acs.est.6b01441

Cited by 1,233Microplastics and Plastic PollutionEnvironmental Toxicology and EcotoxicologyPharmaceutical and Antibiotic Environmental Impacts

Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer ( Brachionus koreanus )

Jeong, Chang-Bum, Won, Eun-Ji, Kang, Hye-Min, Lee, Min-Chul, Hwang, Dae-Sik, Hwang, Un-Ki, Zhou, Bingsheng, Souissi, Sami +2 more·2016·Environmental Science & Technology

DOI 10.1021/acs.est.6b01441

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Abstract

In this study, we evaluated accumulation and adverse effects of ingestion of microplastics in the monogonont rotifer (Brachionus koreanus). The dependence of microplastic toxicity on particle size was investigated by measuring several in vivo end points and studying the ingestion and egestion using 0.05-, 0.5-, and 6-μm nonfunctionalized polystyrene microbeads. To identify the defense mechanisms activated in response to microplastic exposure, the activities of several antioxidant-related enzymes and the phosphorylation status of mitogen-activated protein kinases (MAPKs) were determined. Exposure to polystyrene microbeads of all sizes led to significant size-dependent effects, including reduced growth rate, reduced fecundity, decreased lifespan and longer reproduction time. Rotifers exposed to 6-μm fluorescently labeled microbeads exhibited almost no fluorescence after 24 h, while rotifers exposed to 0.05- and 0.5-μm fluorescently labeled microbeads displayed fluorescence until 48 h, suggesting that 6-μm microbeads are more effectively egested from B. koreanus than 0.05- or 0.5-μm microbeads. This observation provides a potential explanation for our findings that microbead toxicity was size-dependent and smaller microbeads were more toxic. In vitro tests revealed that antioxidant-related enzymes and MAPK signaling pathways were significantly activated in response to microplastic exposure in a size-dependent manner.

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Nanoplastics have high surface to volume ratios and thus better adsorb toxic compounds and potentially transfer them to organisms after ingestion.
“Nanoplastics are characterised by high surface to volume ratios and thus better adsorb toxic compounds and potentially transfers them to organisms aer ingestion.16,18,137,[147][148][149]”
From The fate of plastic in the ocean environment – a minireview (2021) · cites this paper as [148]

Free radicals in biology and medicine
Gutteridge, J. M. C. (1991) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(91)90478-o · Cited by 17,178 · see citing works
Microplastics in the marine environment
Andrady, A. L. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.05.030 · Cited by 8,105 · see citing works
Accumulation and fragmentation of plastic debris in global environments
Barnes, D. K. A., Galgani, F., Thompson, R. C., & Barlaz, M. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0205 · Cited by 6,126 · see citing works
Microplastics as contaminants in the marine environment: A review
Cole, M., Lindeque, P., Halsband, C., & Galloway, T. S. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.09.025 · Cited by 6,023 · see citing works
Microplastic ingestion by zooplankton
Cole, M., Lindeque, P., Fileman, E., Halsband, C., Goodhead, R., Moger, J., & Galloway, T. S. (2013) · Environmental Science & Technology · doi:10.1021/es400663f · Cited by 2,763 · see citing works
Ingested Microscopic Plastic Translocates to the Circulatory System of the Mussel, Mytilus edulis (L.)
Browne, M. A., Dissanayake, A., Galloway, T. S., Lowe, D. M., & Thompson, R. C. (2008) · Environmental Science & Technology · doi:10.1021/es800249a · Cited by 2,263 · see citing works
Size‐Dependent Cytotoxicity of Gold Nanoparticles
Pan, Y., Neuß, S., Leifert, A., Fischler, M., Wen, F., Simon, U., Schmid, G., Brandau, W., & Jahnen‐Dechent, W. (2007) · Small · doi:10.1002/smll.200700378 · Cited by 1,881 · see citing works
Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity
Manke, A., Wang, L., & Rojanasakul, Y. (2013) · BioMed Research International · doi:10.1155/2013/942916 · Cited by 1,736 · see citing works
Uptake and Effects of Microplastics on Cells and Tissue of the Blue Mussel Mytilus edulis L. after an Experimental Exposure
von Moos, N., Burkhardt-Holm, P., & Köhler, A. (2012) · Environmental Science & Technology · doi:10.1021/es302332w · Cited by 1,697 · see citing works
The present and future of microplastic pollution in the marine environment
do Sul, J. A. I., & da Costa, M. F. (2013) · Environmental Pollution · doi:10.1016/j.envpol.2013.10.036 · Cited by 1,604 · see citing works
Size Dependent and Reactive Oxygen Species Related Nanosilver Toxicity to Nitrifying Bacteria
Choi, O., & Hu, Z. (2008) · Environmental Science & Technology · doi:10.1021/es703238h · Cited by 1,398 · see citing works
Engineered nanoparticles interacting with cells: size matters
Shang, L., Nienhaus, K., & Nienhaus, G. U. (2014) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-12-5 · Cited by 1,319 · see citing works
The Impact of Polystyrene Microplastics on Feeding, Function and Fecundity in the Marine Copepod Calanus helgolandicus
Cole, M., Lindeque, P., Fileman, E., Halsband, C., & Galloway, T. S. (2015) · Environmental Science & Technology · doi:10.1021/es504525u · Cited by 1,308 · see citing works
(Nano)plastics in the environment - Sources, fates and effects
da Costa, J. P., Santos, P. S. M., Duarte, A. C., & Rocha-Santos, T. (2016) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.05.041 · Cited by 1,139 · see citing works
Nanoplastic Affects Growth of S. obliquus and Reproduction of D. magna
Besseling, E., Wang, B., Lürling, M., & Koelmans, A. A. (2014) · Environmental Science & Technology · doi:10.1021/es503001d · Cited by 1,138 · see citing works
Polystyrene Spherules in Coastal Waters
Carpenter, E. J., Anderson, S. J., Harvey, G. R., Miklas, H. P., & Peck, B. B. (1972) · Science · doi:10.1126/science.178.4062.749 · Cited by 1,115 · see citing works
Physical Adsorption of Charged Plastic Nanoparticles Affects Algal Photosynthesis
Bhattacharya, P., Lin, S., Turner, J. P., & Ke, P. C. (2010) · The Journal of Physical Chemistry C · doi:10.1021/jp1054759 · Cited by 1,021 · see citing works
Effects of Microplastic on Fitness and PCB Bioaccumulation by the Lugworm Arenicola marina (L.)
Besseling, E., Wegner, A., Foekema, E. M., van den Heuvel-Greve, M. J., & Koelmans, A. A. (2013) · Environmental Science & Technology · doi:10.1021/es302763x · Cited by 1,012 · see citing works
Size-Dependent Effects of Micro Polystyrene Particles in the Marine Copepod Tigriopus japonicus
Lee, K.-W., Shim, W. J., Kwon, O. Y., & Kang, J.-H. (2013) · Environmental Science & Technology · doi:10.1021/es401932b · Cited by 923 · see citing works
Free radicals in biology and medicine
Lucy, J. A. (1985) · FEBS Letters · doi:10.1016/0014-5793(85)80903-0 · Cited by 908 · see citing works
Effects of nanopolystyrene on the feeding behavior of the blue mussel (Mytilus edulis L.)
Wegner, A., Besseling, E., Foekema, E. M., Kamermans, P., & Koelmans, A. A. (2012) · Environmental Toxicology and Chemistry · doi:10.1002/etc.1984 · Cited by 550 · see citing works
Are marine plastic particles transport vectors for organic pollutants to the Arctic?
Zarfl, C., & Matthies, M. (2010) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2010.05.026 · Cited by 395 · see citing works
Rotifers in ecotoxicology: a review
Snell, T. W., & Janssen, C. R. (1995) · Hydrobiologia · doi:10.1007/bf00025956 · Cited by 323 · see citing works
Ecotoxicology, ecophysiology, and mechanistic studies with rotifers
Dahms, H.-U., Hagiwara, A., & Lee, J. (2010) · Aquatic Toxicology · doi:10.1016/j.aquatox.2010.09.006 · Cited by 297 · see citing works
Self-citation
Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways
Chairuangkitti, P., Lawanprasert, S., Roytrakul, S., Aueviriyavit, S., Phummiratch, D., Kulthong, K., Pithi Chanvorachote, B., & Maniratanachote, R. (2012) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.08.021 · Cited by 292 · see citing works
Pelagic Plastics and Other Seaborne Persistent Synthetic Debris: A Review of Southern Hemisphere Perspectives
Gregory, M. R., & Ryan, P. G. (1997) · Springer series on environmental management · doi:10.1007/978-1-4613-8486-1_6 · Cited by 172 · see citing works
Impacts of bleaching on the soft coral Lobophytum compactum . I. Fecundity, fertilization and offspring viability
Michalek-Wagner, K., & Willis, B. L. (2001) · Coral Reefs · doi:10.1007/s003380170003 · Cited by 153 · see citing works
Telmisartan ameliorates cisplatin-induced nephrotoxicity by inhibiting MAPK mediated inflammation and apoptosis
Malik, S., Suchal, K., Gamad, N., Dinda, A. K., Arya, D. S., & Bhatia, J. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.12.008 · Cited by 116 · see citing works
Copper induces apoptotic cell death through reactive oxygen species-triggered oxidative stress in the intertidal copepod Tigriopus japonicus
Rhee, J., Yu, I. T., Kim, B., Jeong, C., Lee, K., Kim, M.-J., Lee, S., Park, G. S., & Lee, J. (2013) · Aquatic Toxicology · doi:10.1016/j.aquatox.2013.02.013 · Cited by 104 · see citing works
Self-citation
Titanium dioxide nanoparticles stimulate sea urchin immune cell phagocytic activity involving TLR/p38 MAPK-mediated signalling pathway
Pinsino, A., Russo, R., Bonaventura, R., Brunelli, A., Marcomini, A., & Matranga, V. (2015) · Scientific Reports · doi:10.1038/srep14492 · Cited by 95 · see citing works
Comparison of TiO2 nanoparticle and graphene–TiO2 nanoparticle composite phototoxicity to Daphnia magna and Oryzias latipes
Li, S., Pan, X., Wallis, L. K., Fan, Z., Chen, Z., & Diamond, S. A. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.03.058 · Cited by 94 · see citing works
A new intertidal Brachionus and intrageneric phylogenetic relationships among Brachionus as revealed by allometry and CO1-ITS1 gene analysis
Hwang, D., Dahms‬, H.-U., Park, H. G., & Lee, J. (2013) · Zoological studies · doi:10.1186/1810-522x-52-13 · Cited by 86 · see citing works
Self-citation
Developmental retardation, reduced fecundity, and modulated expression of the defensome in the intertidal copepod Tigriopus japonicus exposed to BDE-47 and PFOS
Han, J., Won, E., Lee, M., Seo, J. S., Lee, S., & Lee, J. (2015) · Aquatic Toxicology · doi:10.1016/j.aquatox.2015.05.022 · Cited by 71 · see citing works
Self-citation
UV-B radiation-induced oxidative stress and p38 signaling pathway involvement in the benthic copepod Tigriopus japonicus
Kim, B., Rhee, J., Lee, K., Kim, M., Shin, K., Lee, S., Lee, Y.-M., & Lee, J. (2014) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2014.08.003 · Cited by 71 · see citing works
Self-citation
Gamma radiation induces growth retardation, impaired egg production, and oxidative stress in the marine copepod Paracyclopina nana
Won, E., & Lee, J. (2014) · Aquatic Toxicology · doi:10.1016/j.aquatox.2014.02.010 · Cited by 70 · see citing works
Self-citation
Nanoparticles up-regulate tumor necrosis factor-α and CXCL8 via reactive oxygen species and mitogen-activated protein kinase activation
Lee, H.-M., Shin, D.-M., Song, H.-M., Yuk, J.-M., Lee, Z.-W., Lee, S.-H., Hwang, S. M., Kim, J.-M., Lee, C.-S., & Jo, E.-K. (2009) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2009.05.010 · Cited by 67 · see citing works
Self-citation
Complete mitochondrial genome of the monogonont rotifer,Brachionus koreanus(Rotifera, Brachionidae)
Hwang, D., Suga, K., Sakakura, Y., Park, H. G., Hagiwara, A., Rhee, J., & Lee, J. (2013) · Mitochondrial DNA · doi:10.3109/19401736.2013.775274 · Cited by 67 · see citing works
Self-citation
Multi-walled carbon nanotubes (MWCNTs) lead to growth retardation, antioxidant depletion, and activation of the ERK signaling pathway but decrease copper bioavailability in the monogonont rotifer (Brachionus koreanus)
Lee, J. W., Kang, H.-M., Won, E., Hwang, D.-S., Kim, D., Lee, J., & Lee, J. (2016) · Aquatic Toxicology · doi:10.1016/j.aquatox.2015.12.022 · Cited by 39 · see citing works
Self-citation
Annelids and Nematodes as Sentinels of Environmental Pollution
Monserrat, J. M., da Rosa, C. E., Sandrini, J. Z., Marins, L. F., Bianchini, A., & Geracitano, L. A. (2003) · Comments on Toxicology · doi:10.1080/08865140390450386 · Cited by 30 · see citing works
Size-dependent toxicity of silver nanoparticles to Glyptotendipes tokunagai
Choi, S., Kim, S., Bae, Y.-J., Park, J., & Jung, J. (2015) · Environmental Health and Toxicology · doi:10.5620/eht.e2015003 · Cited by 22 · see citing works

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Microplastics in Freshwater and Terrestrial Environments: Evaluating the Current Understanding to Identify the Knowledge Gaps and Future Research Priorities
Horton, A. A., Walton, A., Spurgeon, D. J., Lahive, E., & Svendsen, C. (2017) · Science of The Total Environment · doi:10.1016/j.scitotenv.2017.01.190 · Cited by 3,756 · see citing works
“These smaller fragments are likely to pose a greater risk to organism 807 health due to their increased likelihood of uptake, increased surface area for interactions with 808 chemicals and greater number of particles per unit of bulk mass (Jeong et al., 2016; Lee et al., 2013).”
Background
Microplastics as an emerging threat to terrestrial ecosystems
Machado, A. A. D. S., Kloas, W., Zarfl, C., Hempel, S., & Rillig, M. C. (2017) · Global Change Biology · doi:10.1111/gcb.14020 · Cited by 2,381 · see citing works
Microplastics in wastewater treatment plants: Detection, occurrence and removal
Sun, J., Dai, X., Wang, Q., van Loosdrecht, M. C. M., & Ni, B. (2019) · Water Research · doi:10.1016/j.watres.2018.12.050 · Cited by 2,033 · see citing works
Interactions of microplastic debris throughout the marine ecosystem
Galloway, T. S., Cole, M., & Lewis, C. (2017) · Nature Ecology & Evolution · doi:10.1038/s41559-017-0116 · Cited by 1,955 · see citing works
Microplastic particles cause intestinal damage and other adverse effects in zebrafish Danio rerio and nematode Caenorhabditis elegans
Lei, L., Wu, S., Lu, S., Liu, M., Song, Y., Fu, Z., Shi, H., Raley‐Susman, K. M., & He, D. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.11.103 · Cited by 1,399 · see citing works
Agricultural plastic mulching as a source of microplastics in the terrestrial environment
Huang, Y., Liu, Q., Jia, W., Yan, C., & Wang, J. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114096 · Cited by 1,348 · see citing works
Studies of the Effects of Microplastics on Aquatic Organisms: What Do We Know and Where Should We Focus Our Efforts in the Future?
de Sá, L. C., Oliveira, M., Ribeiro, F., Rocha, T. L., & Futter, M. N. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.07.207 · Cited by 1,316 · see citing works
Risk assessment of microplastic particles
Koelmans, A., Redondo-Hasselerharm, P., Nor, N. H. M., de Ruijter, V. D., Mintenig, S., & Kooi, M. (2022) · Nature Reviews Materials · doi:10.1038/s41578-021-00411-y · Cited by 964 · see citing works
Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice
Jin, Y., Lu, L., Tu, W., Luo, T., & Fu, Z. (2019) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.08.353 · Cited by 1,100 · see citing works
Environmental source, fate, and toxicity of microplastics
Wang, C., Zhao, J. L., & Xing, B. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124357 · Cited by 1,093 · see citing works
Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice
Lu, L., Wan, Z., Luo, T., Fu, Z., & Jin, Y. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.03.051 · Cited by 1,059 · see citing works
Source and potential risk assessment of suspended atmospheric microplastics in Shanghai.
Liu, K., Wang, X.-H., Fang, T., Xu, P., Zhu, L.-X., & Li, D.-J. (2019) · Science of the Total Environment · doi:10.1016/j.scitotenv.2019.04.110 · Cited by 801 · see citing works
New Insights into the Aging Behavior of Microplastics Accelerated by Advanced Oxidation Processes.
Liu, P., Qian, L., Wang, H., Zhan, X., Lu, K., Gu, C., & Gao, S. (2019) · Environmental Science and Technology · doi:10.1021/acs.est.9b00493 · Cited by 799 · see citing works
Accumulation of different shapes of microplastics initiates intestinal injury and gut microbiota dysbiosis in the gut of zebrafish
Qiao, R., Deng, Y., Zhang, S., Wolosker, M. B., Zhu, Q., Ren, H., & Zhang, Y. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.07.065 · Cited by 924 · see citing works
Microplastics in aquatic environments: Occurrence, accumulation, and biological effects
Xu, S., Ma, J., Ji, R., Pan, K., & Miao, A. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.134699 · Cited by 882 · see citing works
Polystyrene microplastics induce microbiota dysbiosis and inflammation in the gut of adult zebrafish
Jin, Y., Xia, J., Pan, Z., Yang, J., Wang, W., & Fu, Z. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2017.12.088 · Cited by 873 · see citing works
“…and mechanical damages (Jovanovi c, 2017; Ped a et al., 2017) but also block the digestive tract, reduce growth rates, block enzyme production, induce oxidative stress and even affect reproduction (Wright et al., 2013b; Jeong et al., 2016; Sussarellu et al., 2016; Rodriguez-Seijo et al., 2017).”
Background
Microplastics and associated contaminants in the aquatic environment: A review on their ecotoxicological effects, trophic transfer, and potential impacts to human health
Huang, W., Song, B., Liang, J., Niu, Q., Zeng, G., Shen, M., Deng, J., Luo, Y., Wen, X., & Zhang, Y. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124187 · Cited by 801 · see citing works
Effect of weathering on environmental behavior of microplastics: properties, sorption and potential risks
Liu, P., Zhan, X., Wu, X., Li, J., Wang, H., & Gao, S. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2019.125193 · Cited by 756 · see citing works
Accumulation, tissue distribution, and biochemical effects of polystyrene microplastics in the freshwater fish red tilapia (Oreochromis niloticus)
Ding, J., Zhang, S., Razanajatovo, R. M., Zou, H., & Zhu, W. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.03.001 · Cited by 766 · see citing works
Mini-review of microplastics in the atmosphere and their risks to humans
Chen, G., Feng, Q., & Wang, J. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.135504 · Cited by 778 · see citing works
Microplastics: A Real Global Threat for Environment and Food Safety: A State of the Art Review
Ziani, K., Ioniță-Mîndrican, C.-B., Mititelu, M., Neacșu, S. M., Negrei, C., Moroșan, E., Drăgănescu, D., & Preda, O.-T. (2023) · Nutrients · doi:10.3390/nu15030617 · Cited by 782 · see citing works
Phytoplankton response to polystyrene microplastics: Perspective from an entire growth period
Mao, Y., Ai, H., Chen, Y., Zhang, Z., Zeng, P., Kang, L., Li, W., Gu, W., He, Q., & Li, H. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.05.170 · Cited by 713 · see citing works
Potential toxicity of polystyrene microplastic particles
Hwang, J., Choi, D., Han, S., Jung, S. Y., Choi, J. H., & Hong, J. (2020) · Scientific Reports · doi:10.1038/s41598-020-64464-9 · Cited by 723 · see citing works
A meta-analysis of the effects of exposure to microplastics on fish and aquatic invertebrates.
Foley, C. J., Feiner, Z. S., Malinich, T. D., & Höök, T. (2018) · Science of the Total Environment · doi:10.1016/j.scitotenv.2018.03.046 · Cited by 566 · see citing works
A review of the removal of microplastics in global wastewater treatment plants: characteristics and mechanisms
Liu, W., Zhang, J., Liu, H., Guo, X., Zhang, X., Yao, X., Cao, Z., & Zhang, T. (2021) · Environment International · doi:10.1016/j.envint.2020.106277 · Cited by 631 · see citing works
Polystyrene microplastics induced male reproductive toxicity in mice
Jin, H., Ma, T., Sha, X., Liu, Z., Zhou, Y., Meng, X., Chen, Y., Han, X., & Ding, J. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123430 · Cited by 660 · see citing works
Effects of micro- and nanoplastics on aquatic ecosystems: Current research trends and perspectives
Chae, Y., & An, Y. (2017) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2017.01.070 · Cited by 652 · see citing works
Micro- and nano-plastics activation of oxidative and inflammatory adverse outcome pathways
Hu, M., & Palić, D. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101620 · Cited by 647 · see citing works
Marine microplastics as vectors of major ocean pollutants and its hazards to the marine ecosystem and humans
Amelia, T. S. M., Khalik, W. M. A. W. M., Ong, M. C., Shao, Y. T., Pan, H.-J., & Bhubalan, K. (2021) · Progress in Earth and Planetary Science · doi:10.1186/s40645-020-00405-4 · Cited by 641 · see citing works
“…severe intestinal damage, and mortality (Besseling et al. 2015; Betts 2008; Courtene-Jones et al. 2017; Gambardella et al. 2017; Greven et al. 2016; Jeong et al. 2016; Jovanovic 2017; Lei et al. 2018; Leroueil et al. 2008; Naidu et al. 2018; Nakki et al. 2017; Prokic et al. 2019; Savoca et al.…”
Background
Environmental behaviors of microplastics in aquatic systems: A systematic review on degradation, adsorption, toxicity and biofilm under aging conditions
Luo, H., Liu, C., He, D., Xu, J., Sun, J., Li, J., & Pan, X. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.126915 · Cited by 620 · see citing works
A critical review on the interactions of microplastics with heavy metals: Mechanism and their combined effect on organisms and humans
Cao, Y., Zhao, M., Ma, X., Song, Y., Zuo, S., Li, H., & Deng, W. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.147620 · Cited by 611 · see citing works
Microplastics and seafood: lower trophic organisms at highest risk of contamination
Walkinshaw, C., Lindeque, P. K., Thompson, R. C., Tolhurst, T. J., & Cole, M. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.110066 · Cited by 605 · see citing works
“…suggesting that PS-MPs did not induce adverse hepatic stress in rainbow trout; however, Ašmonaitė et al. (2018) theorize that this may be due to the size of the PS-MPs used, as oxidative stress effects have been observed for smaller polystyrene particles (Jeong et al. , 2016; Lei et al. , 2018).”
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Zhang, Z., & Chen, Y. (2019) · Chemical Engineering Journal · doi:10.1016/j.cej.2019.122955 · Cited by 586 · see citing works
Adverse effects of microplastics and oxidative stress-induced MAPK/Nrf2 pathway-mediated defense mechanisms in the marine copepod Paracyclopina nana
Jeong, C.-B., Kang, H.-M., Lee, M.-C., Kim, D.-H., Han, J., Hwang, D.-S., Souissi, S., Lee, S.-J., Shin, K., Park, H., et al. (2017) · Scientific Reports · doi:10.1038/srep41323 · Cited by 524 · see citing works
Self-citation
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Ma, H., Pu, S., Liu, S., Bai, Y., Mandal, S., & Xing, B. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114089 · Cited by 597 · see citing works
Quantifying ecological risks of aquatic micro- and nanoplastic
Besseling, E., Redondo-Hasselerharm, P., Foekema, E. M., & Koelmans, A. A. (2019) · Critical Reviews in Environmental Science and Technology · doi:10.1080/10643389.2018.1531688 · Cited by 564 · see citing works
“A similar approach of combining data for freshwater and marine invertebrate species has been used for pesticide risk assessment (Diepens et al., 2016; Jeong et al., 2016).”
Background
Risk assessment of microplastics in the ocean: Modelling approach and first conclusions
Everaert, G., Cauwenberghe, L. V., Rijcke, M. D., Koelmans, A. A., Mees, J., Vandegehuchte, M., & Janssen, C. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.07.069 · Cited by 547 · see citing works
Micro- and nanoplastic toxicity on aquatic life: Determining factors
Kögel, T., Bjorøy, Ø., Toto, B., Bienfait, A. M., & Sanden, M. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2019.136050 · Cited by 518 · see citing works
Ecotoxicological effects of microplastics: Examination of biomarkers, current state and future perspectives
Prokić, M. D., Radovanović, T. B., Gavrić, J. P., & Faggio, C. (2018) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2018.12.001 · Cited by 530 · see citing works
Effects of polystyrene microplastics on the composition of the microbiome and metabolism in larval zebrafish
Wan, Z., Wang, C., Zhou, J., Shen, M., Wang, X., Fu, Z., & Jin, Y. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.11.070 · Cited by 503 · see citing works
Influence of microplastics on the accumulation and chronic toxic effects of cadmium in zebrafish (Danio rerio)
Lü, K., Qiao, R., An, H., & Zhang, Y. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.03.145 · Cited by 486 · see citing works
Reporting Guidelines to Increase the Reproducibility and Comparability of Research on Microplastics
Cowger, W., Booth, A. M., Hamilton, B. M., Thaysen, C., Primpke, S., Munno, K., Lusher, A., Dehaut, A., Vaz, V. P., Liboiron, M., et al. (2020) · Applied Spectroscopy · doi:10.1177/0003702820930292 · Cited by 488 · see citing works
Microplastic pollution identified in deep-sea water and ingested by benthic invertebrates in the Rockall Trough, North Atlantic Ocean
Courtene‐Jones, W., Quinn, B., Gary, S. F., Mogg, A. O. M., & Narayanaswamy, B. E. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.08.026 · Cited by 466 · see citing works
Microplastics removal in wastewater treatment plants: a critical review
Iyare, P. U., Ouki, S. K., & Bond, T. (2020) · Environmental Science Water Research & Technology · doi:10.1039/d0ew00397b · Cited by 472 · see citing works
Microplastic Contamination in Freshwater Environments: A Review, Focusing on Interactions with Sediments and Benthic Organisms
Bellasi, A., Binda, G., Pozzi, A., Galafassi, S., Volta, P., & Bettinetti, R. (2020) · Environments · doi:10.3390/environments7040030 · Cited by 449 · see citing works
“In addition to problems related with feeding inhibition (including consequent effects on reproduction and growth), some authors also consider physiological effects on cellular stress and oxidative damage [146,147].”
Background
Polyvinyl Chloride Microplastics Affect Methane Production from the Anaerobic Digestion of Waste Activated Sludge through Leaching Toxic Bisphenol-A
Wei, W., Huang, Q.-S., Sun, J., Wang, J., Wu, S.-L., & Ni, B. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.8b07069 · Cited by 442 · see citing works
A comparative review of microplastics and nanoplastics: Toxicity hazards on digestive, reproductive and nervous system
Yin, K., Wang, Y., Zhao, H., Wang, D., Guo, M., Mu, M., Liu, Y., Nie, X., Li, B., Li, J., et al. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.145758 · Cited by 437 · see citing works
Polystyrene (nano)microplastics cause size-dependent neurotoxicity, oxidative damage and other adverse effects in Caenorhabditis elegans
Lei, L., Liu, M., Song, Y., Lu, S., Hu, J., Cao, C., Xie, B., Shi, H., & He, D. (2018) · Environmental Science Nano · doi:10.1039/c8en00412a · Cited by 429 · see citing works
Maternal transfer of nanoplastics to offspring in zebrafish (Danio rerio): A case study with nanopolystyrene
Pitt, J. A., Trevisan, R., Massarsky, A., Kozal, J. S., Levin, E. D., & Di Giulio, R. T. (2018) · Science of The Total Environment · doi:10.1016/j.scitotenv.2018.06.186 · Cited by 413 · see citing works
“In addition, micro- and nano-sized polystyrene particles were shown to have pro-oxidant properties, leading to decreased levels of reduced glutathione in zebrafish larvae, and increased ROS levels and antioxidant enzyme activities in copepods Paracyclopina nana (Chen et al., 2017; Jeong et al., 2017; Jeong et al., 201…”
Background
Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications
Wu, P., Lin, S., Cao, G., Wu, J., Jin, H., Wang, C., Wong, M. H., Yang, Z., & Cai, Z. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129361 · Cited by 428 · see citing works
Microplastic pollution in North Yellow Sea, China: Observations on occurrence, distribution and identification
Zhu, L., Bai, H., Chen, B., Sun, X., Qu, K., & Xia, B. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.04.182 · Cited by 425 · see citing works
Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health
Lu, L., Luo, T., Zhao, Y., Cai, C., Fu, Z., & Jin, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.02.380 · Cited by 423 · see citing works
Release of hazardous nanoplastic contaminants due to microplastics fragmentation under shear stress forces
Enfrin, M., Lee, J., Gibert, Y., Basheer, F., Kong, L., & Dumée, L. F. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.121393 · Cited by 410 · see citing works
Self-citation
Effects of nanoplastics on Mytilus galloprovincialis after individual and combined exposure with carbamazepine
Brandts, I., Teles, M., Gonçalves, A. P., Barreto, Â., Franco‐Martínez, L., Tvarijonaviciute, A., Martins, M. A., Soares, A. M. V. M., Tort, L., & Oliveira, M. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.06.257 · Cited by 389 · see citing works
Toxicological effects of irregularly shaped and spherical microplastics in a marine teleost, the sheepshead minnow (Cyprinodon variegatus)
Choi, J. S., Jung, Y.-J., Hong, N.-H., Hong, S. H., & Park, J. (2018) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2018.02.039 · Cited by 390 · see citing works
The emerging role of microplastics in systemic toxicity: Involvement of reactive oxygen species (ROS)
Das, A. K. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165076 · Cited by 384 · see citing works
Revealing the Mechanisms of Polyethylene Microplastics Affecting Anaerobic Digestion of Waste Activated Sludge
Wei, W., Huang, Q.-S., Sun, J., Dai, X., & Ni, B. (2019) · Environmental Science & Technology · doi:10.1021/acs.est.9b02971 · Cited by 377 · see citing works
Microplastics as an emerging threat to plant and soil health in agroecosystems
Zhou, J., Wen, Y., Marshall, M. R., Zhao, J., Gui, H., Yang, Y., Zeng, Z., Jones, D. L., & Zang, H. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.147444 · Cited by 379 · see citing works
Quantitative tracing of uptake and transport of submicrometre plastics in crop plants using lanthanide chelates as a dual-functional tracer
Luo, Y., Li, L., Feng, Y., Li, R., Yang, J., Peijnenburg, W. J. G. M., & Tu, C. (2022) · Nature Nanotechnology · doi:10.1038/s41565-021-01063-3 · Cited by 376 · see citing works
Urban stormwater runoff: a major pathway for anthropogenic particles, black rubbery fragments, and other types of microplastics to urban receiving waters
Werbowski, L. M., Gilbreath, A. N., Munno, K., Zhu, X., Grbic, J., Wu, T., Sutton, R., Sedlak, M. D., Deshpande, A. D., & Rochman, C. M. (2021) · ACS ES&T Water · doi:10.1021/acsestwater.1c00017 · Cited by 359 · see citing works
Aging of microplastics affects their surface properties, thermal decomposition, additives leaching and interactions in simulated fluids
Luo, H., Zhao, Y., Li, Y., Xiang, Y., He, D., & Pan, X. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.136862 · Cited by 355 · see citing works
Microplastic exposure and effects in aquatic organisms: A physiological perspective
Franzellitti, S., Canesi, L., Auguste, M., Wathsala, R. H. G. R., & Fabbri, E. (2019) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2019.03.009 · Cited by 366 · see citing works
Microplastics and Oxidative Stress—Current Problems and Prospects
Kadac-Czapska, K., Ośko, J., Knez, E., & Grembecka, M. (2024) · Antioxidants · doi:10.3390/antiox13050579 · Cited by 372 · see citing works
“The activation of mitogen-activated protein kinase (MAPK) pathways is the underlying cause of MPs’ detrimental e ﬀ ects on health.”
BackgroundMethodInfluential
Negligible effects of microplastics on animal fitness and HOC bioaccumulation in earthworm Eisenia fetida in soil
Wang, J., Coffin, S., Sun, C., Schlenk, D., & Gan, J. J. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.03.102 · Cited by 343 · see citing works
Closing the gap between small and smaller: towards a framework to analyse nano- and microplastics in aqueous environmental samples
Mintenig, S. M., Bäuerlein, P. S., Koelmans, A. A., Dekker, S. C., & van Wezel, A. P. (2018) · Environmental Science Nano · doi:10.1039/c8en00186c · Cited by 338 · see citing works
Accurate quantification and transport estimation of suspended atmospheric microplastics in megacities: Implications for human health.
Liu, K., Wang, X.-H., Wei, N., Song, Z.-Y., & Li, D.-J. (2019) · Environment International · doi:10.1016/j.envint.2019.105127 · Cited by 277 · see citing works
“Potential health risks may be aggravated by smaller-sized SAMPs, which pose more of a threat to aquatic organisms than larger SAMPs (Jeong et al., 2016).”
Background
Environmentally relevant concentrations of polyethylene microplastics negatively impact the survival, growth and emergence of sediment-dwelling invertebrates
Ziajahromi, S., Kumar, A., Neale, P. A., & Leusch, F. D. L. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.01.094 · Cited by 325 · see citing works
The fate of plastic in the ocean environment – a minireview
Wayman, C., & Niemann, H. (2021) · Environmental Science: Processes & Impacts · doi:10.1039/d0em00446d · Cited by 325 · see citing works
Toxicity comparison of nano-sized and micron-sized microplastics to Goldfish Carassius auratus Larvae
Yang, H., Xiong, H., Mi, K., Xue, W., Wei, W., & Zhang, Y. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122058 · Cited by 326 · see citing works
The emerging risk of exposure to nano(micro)plastics on endocrine disturbance and reproductive toxicity: From a hypothetical scenario to a global public health challenge
Amereh, F., Babaei, M., Eslami, A., Fazelipour, S., & Rafiee, M. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114158 · Cited by 322 · see citing works
Polyvinyl chloride microplastics induce growth inhibition and oxidative stress in Cyprinus carpio var. larvae
Xia, X., Sun, M., Zhou, M., Chang, Z., & Li, L. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.136479 · Cited by 313 · see citing works
Effect of salinity and humic acid on the aggregation and toxicity of polystyrene nanoplastics with different functional groups and charges
Wu, J., Jiang, R., Lin, W., & Ouyang, G. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2018.11.055 · Cited by 309 · see citing works
Nanoplastics formed during the mechanical breakdown of daily-use polystyrene products
Ekvall, M. T., Lundqvist, M., Kelpsiene, E., Šileikis, E., Gunnarsson, S. B., & Cedervall, T. (2019) · Nanoscale Advances · doi:10.1039/c8na00210j · Cited by 304 · see citing works
Effects of microplastics on the innate immunity and intestinal microflora of juvenile Eriocheir sinensis
Liu, Z., Yu, P., Cai, M., Wu, D., Zhang, M., Chen, M., & Zhao, Y. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.06.265 · Cited by 307 · see citing works
Critical Review of Processing and Classification Techniques for Images and Spectra in Microplastic Research
Cowger, W., Gray, A. B., Christiansen, S. H., Frond, H. D., Deshpande, A. D., Hermabessière, L., Lee, E., Mill, L., Munno, K., Oßmann, B. E., et al. (2020) · Applied Spectroscopy · doi:10.1177/0003702820929064 · Cited by 312 · see citing works
“Exact size dimensions of particles can aid in fate and transport analysis and modeling as well as risk assessment.(32,33) For fibers, the total length (long axis) of the fiber can be traced using straight or segmented lines, which may be useful for calculating volume since the width of fibers is relatively symmetric.”
Background
Polyethylene microplastics adhere to Lemna minor (L.), yet have no effects on plant growth or feeding by Gammarus duebeni (Lillj.)
Mateos-Cárdenas, A., Scott, D. T., Seitmaganbetova, G., van Pelt Frank, N. A. M., O’Halloran, J., & Jansen, M. A. K. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.06.359 · Cited by 307 · see citing works
Microplastics increase mercury bioconcentration in gills and bioaccumulation in the liver, and cause oxidative stress and damage in Dicentrarchus labrax juveniles
Barboza, L. G. A., Vieira, L. R., Branco, V., Carvalho, C. M. L., & Guilhermino, L. M. (2018) · Scientific Reports · doi:10.1038/s41598-018-34125-z · Cited by 306 · see citing works
Acute microplastic exposure raises stress response and suppresses detoxification and immune capacities in the scleractinian coral Pocillopora damicornis
Tang, J., Ni, X., Zhou, Z., Wang, L., & Lin, S. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.08.045 · Cited by 302 · see citing works
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats
Li, Z., Zhu, S., Liu, Q., Wei, J., Jin, Y., Wang, X., & Zhang, L. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.115025 · Cited by 301 · see citing works
Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation
Park, E., Han, J.-S., Park, E.-J., Seong, E., Lee, G., Kim, D., Son, H., Han, H., & Lee, B. (2020) · Toxicology Letters · doi:10.1016/j.toxlet.2020.01.008 · Cited by 305 · see citing works
Assessment on interactive prospectives of nanoplastics with plasma proteins and the toxicological impacts of virgin, coronated and environmentally released-nanoplastics
Gopinath, P. M., Saranya, V., Vijayakumar, S., Meera, M. M., Ruprekha, S., Kunal, R., Agarwal, P., Thomas, J., Mukherjee, A., & Chandrasekaran, N. (2019) · Scientific Reports · doi:10.1038/s41598-019-45139-6 · Cited by 303 · see citing works
Effects of polystyrene microbeads in marine planktonic crustaceans
Gambardella, C., Morgana, S., Ferrando, S., Bramini, M., Piazza, V., Costa, E., Garaventa, F., & Faimali, M. (2017) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2017.07.036 · Cited by 296 · see citing works
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway
Jin, H., Yan, M., Pan, C., Liu, Z., Sha, X., Jiang, C., Li, L., Pan, M., Li, D., Han, X., et al. (2022) · Particle and Fibre Toxicology · doi:10.1186/s12989-022-00453-2 · Cited by 306 · see citing works
Polystyrene nanoplastic exposure induces immobilization, reproduction, and stress defense in the freshwater cladoceran Daphnia pulex
Liu, Z., Yu, P., Cai, M., Wu, D., Zhang, M., Huang, Y., & Zhao, Y. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.09.176 · Cited by 297 · see citing works
Nanoplastics impaired oyster free living stages, gametes and embryos
Tallec, K., Huvet, A., Poi, C. D., González-Fernández, C., Christophe Lambert, B., Petton, B., Goïc, N. L., Berchel, M., Soudant, P., & Paul-Pont, I. (2018) · Environmental Pollution · doi:10.1016/j.envpol.2018.08.020 · Cited by 293 · see citing works
Environmental health impacts of microplastics exposure on structural organization levels in the human body
Yang, X., Man, Y. B., Wong, M. H., Owen, R. B., & Chow, K. L. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154025 · Cited by 281 · see citing works
Spatial-temporal distribution of microplastics in surface water and sediments of Maozhou River within Guangdong-Hong Kong-Macao Greater Bay Area
Wu, P., Tang, Y., Dang, M., Wang, S., Jin, H., Liu, Y., Jing, H., Zheng, C., Yi, S., & Cai, Z. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.135187 · Cited by 276 · see citing works
Impacts of nanoplastics on bivalve: Fluorescence tracing of organ accumulation, oxidative stress and damage
Li, Z., Feng, C., Wu, Y., & Guo, X. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122418 · Cited by 278 · see citing works
Constraints and Priorities for Conducting Experimental Exposures of Marine Organisms to Microplastics
Paul-Pont, I., Tallec, K., González-Fernández, C., Christophe Lambert, B., Vincent, D., Mazurais, D., Zambonino‐Infante, J., Brotons, G., Lagarde, F., Fabioux, C., et al. (2018) · Frontiers in Marine Science · doi:10.3389/fmars.2018.00252 · Cited by 270 · see citing works
“Effects were also reported to be sizedependent, especially for nanometric sizes, due to the physicochemical properties of NP (Lee et al., 2013; Jeong et al., 2016, 2017; Mattsson et al., 2017).”
BackgroundMethod
Toxicological effects of nano- and micro-polystyrene plastics on red tilapia: Are larger plastic particles more harmless?
Ding, J., Huang, Y., Liu, S., Zhang, S., Zou, H., Wang, Z., Zhu, W., & Geng, J. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122693 · Cited by 270 · see citing works
Different effects of nano- and microplastics on oxidative status and gut microbiota in the marine medaka Oryzias melastigma
Kang, H.-M., Byeon, E., Jeong, H., Kim, M., Chen, Q., & Lee, J. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124207 · Cited by 264 · see citing works
Self-citation
Micro/nano-plastics occurrence, identification, risk analysis and mitigation: challenges and perspectives
Kiran, B. R., Kopperi, H., & Mohan, S. V. (2022) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-021-09609-6 · Cited by 278 · see citing works
“Due to protozoa or metazoan feeding, MPs might be trapped in sludge flocs (Scherer et al. 2018; Jeong et al. 2016).”
Background
Dietary administration of PVC and PE microplastics produces histological damage, oxidative stress and immunoregulation in European sea bass (Dicentrarchus labrax L.)
Espinosa‐Ruíz, C., Esteban, M. Á., & Cuesta, A. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.10.072 · Cited by 267 · see citing works
From natural environment to animal tissues: A review of microplastics(nanoplastics) translocation and hazards studies
Dong, X., Liu, X., Hou, Q., & Wang, Z. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.158686 · Cited by 269 · see citing works
Kinetic and mechanistic aspects of ultrafiltration membrane fouling by nano- and microplastics
Enfrin, M., Lee, J., Le‐Clech, P., & Dumée, L. F. (2020) · Journal of Membrane Science · doi:10.1016/j.memsci.2020.117890 · Cited by 265 · see citing works
Self-citation
Microplastic residues in wetland ecosystems: Do they truly threaten the plant-microbe-soil system?
Yu, H., Qi, W., Cao, X., Hu, J., Li, Y., Peng, J., Hu, C., & Qu, J. (2021) · Environment International · doi:10.1016/j.envint.2021.106708 · Cited by 266 · see citing works
Effects of microplastics and nanoplastics on marine environment and human health
Sana, S. S., Dogiparthi, L. K., Gangadhar, L., Chakravorty, A., & Abhishek, N. (2020) · Environmental science and pollution research international · doi:10.1007/s11356-020-10573-x · Cited by 203 · see citing works
“They have accumulated and persisted for years to centuries in aquatic habitats (Jeong et al. 2016) and are the main problem for the toxicity of plastic waste (Bergmann et al. 2015).”
BackgroundInfluential
Nanoplastic Ingestion Enhances Toxicity of Persistent Organic Pollutants (POPs) in the Monogonont Rotifer Brachionus koreanus via Multixenobiotic Resistance (MXR) Disruption
Jeong, C.-B., Kang, H.-M., Lee, Y. H., Kim, M.-S., Lee, J.-S., Seo, J. S., Wang, M., & Lee, J.-S. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.8b03211 · Cited by 263 · see citing works
Self-citation
Uptake and cellular effects of PE, PP, PET and PVC microplastic particles
Stock, V., Laurisch, C., Franke, J., Dönmez, M. H., Voß, L., Böhmert, L., Braeuning, A., & Sieg, H. (2020) · Toxicology in Vitro · doi:10.1016/j.tiv.2020.105021 · Cited by 262 · see citing works
Environmental fate and impacts of microplastics in aquatic ecosystems: A review
Du, S., Zhu, R., Cai, Y., Xu, N., Yap, P.-S., Zhang, Y., He, Y., & Zhang, Y. (2021) · RSC Advances · doi:10.1039/d1ra00880c · Cited by 261 · see citing works

Metabolism deficiency and oxidative stress induced by plastic particles in the rotifer Brachionus plicatilis: Common and distinct phenotypic and transcriptomic responses to nano- and microplastics
Shin, H., & Jeong, C. (2022) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2022.113981 · Cited by 27 · see citing works
Self-citation
Evaluation of microplastic toxicity in accordance with different sizes and exposure times in the marine copepod Tigriopus japonicus
Choi, J. S., Hong, S. H., & Park, J. (2019) · Marine Environmental Research · doi:10.1016/j.marenvres.2019.104838 · Cited by 216 · see citing works
Effects of polypropylene and polyethylene on the antioxidant system of the marine rotifer Brachionus koreanus
Park, J. S., Yoo, J.-W., & Lee, Y. (2024) · Toxicology and Environmental Health Sciences · doi:10.1007/s13530-024-00224-w · Cited by 5 · see citing works
Effects of polystyrene in the brackish water flea Diaphanosoma celebensis: Size-dependent acute toxicity, ingestion, egestion, and antioxidant response
Yoo, J.-W., Cho, H., Jeon, M., Jeong, C., Jung, J.-H., & Lee, Y. (2021) · Aquatic Toxicology · doi:10.1016/j.aquatox.2021.105821 · Cited by 53 · see citing works
Self-citation
Comparative impacts of fragmented versus spherical microplastics on the marine rotifer Brachionus koreanus: Multigenerational chronic toxicity and multi-omics perspective
Yoo, J.-W., Choi, T.-J., Park, J. S., Lee, Y.-H., Hwang, D. H., Kim, C.-B., Jeong, T., & Lee, Y.-M. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.139094 · Cited by 6 · see citing works
Self-citation

Authors: Jeong, C.-B., Won, E.-J., Kang, H.-M., Lee, M.-C., Hwang, D.-S., Hwang, U.-K., Zhou, B., Souissi, S., Lee, S.-J., & Lee, J.-S.
Affiliations: Hanyang University (KR)
Korea Institute of Ocean Science and Technology (KR)
Sungkyunkwan University (KR)
National Institute of Fisheries Science (KR)
Chinese Academy of Sciences (CN)
Centre National de la Recherche Scientifique (FR)
Corresponding author: Lee, Jae-Seong
ORCID: Jeong, Chang-Bum
Won, Eun-Ji
Lee, Min-Chul
Hwang, Un-Ki
Zhou, Bingsheng
Souissi, Sami
Lee, Su-Jae
Lee, Jae-Seong
Venue: Environmental Science & Technology
Publisher: American Chemical Society (ACS)
Published: 2016-08-04
Volume: 50
Issue: 16
Pages: 8849-8857
ISSN: 0013-936X (ISSN-L)
1520-5851
DOI: 10.1021/acs.est.6b01441
OpenAlex: W2505003366
Cited by: 1,233
References: 40
Citations by year: 2026: 97 · 2025: 131 · 2024: 159 · 2023: 180 · 2022: 189 · 2021: 148 · 2020: 165 · 2019: 89 · 2018: 57 · 2017: 15 · 2016: 2 · 2013: 1
FWCI: 29.62
Type: journal article
Language: en
Open access: closed
Locations: Environmental Science & Technology (publishedVersion)
PubMed (publishedVersion)
Institute of Hydrobiology, CAS Institutional Repository (submittedVersion)
Funders: Ministry of Oceans and Fisheries (20150342, PM15050)
Topics: Physical Sciences › Environmental Science › Pollution › Microplastics and Plastic Pollution
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
Keywords: microplastics, size-dependent toxicity, polystyrene microspheres, oxidative stress, antioxidant enzymes, MAPK signaling, JNK phosphorylation, p38 phosphorylation, growth rate, fecundity, lifespan, microplastic accumulation
MeSH terms: Animals, Antioxidants, Rotifera, Oxidative Stress, Mitogen-Activated Protein Kinases

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Microplastic Size-Dependent Toxicity, Oxidative Stress Induction, and p-JNK and p-p38 Activation in the Monogonont Rotifer ( Brachionus koreanus )

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