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Cited by 253

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Quantum dot-based theranostics

Open access
Ho, Yi-Ping, Leong, Kam W.·2010·Nanoscale
DOI 10.1039/b9nr00178f
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Abstract

Luminescent semiconductor nanocrystals, also known as quantum dots (QDs), have advanced the fields of molecular diagnostics and nanotherapeutics. Much of the initial progress for QDs in biology and medicine has focused on developing new biosensing formats to push the limit of detection sensitivity. Nevertheless, QDs can be more than passive bio-probes or labels for biological imaging and cellular studies. The high surface-to-volume ratio of QDs enables the construction of a "smart" multifunctional nanoplatform, where the QDs serve not only as an imaging agent but also a nanoscaffold catering for therapeutic and diagnostic (theranostic) modalities. This mini review highlights the emerging applications of functionalized QDs as fluorescence contrast agents for imaging or as nanoscale vehicles for delivery of therapeutics, with special attention paid to the promise and challenges towards QD-based theranostics.

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Metadata

Authors
Ho, Y.-P., & Leong, K. W.
Venue
Nanoscale
Publisher
Royal Society of Chemistry (RSC)
Published
2010
Volume
2
Issue
1
Pages
60-68
ISSN
  • 2040-3364 (ISSN-L)
  • 2040-3372
DOI
10.1039/b9nr00178f
OpenAlex
W2149933383
Cited by
253
References
3
FWCI
7.66
Type
journal article
Language
en
Open access
green

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Ho, Y.-P., & Leong, K. W. (2010). Quantum dot-based theranostics. Nanoscale. https://doi.org/10.1039/b9nr00178f

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