Organ-on-a-chip devices advance to market
Abstract
We reviewed the foundational technologies underlying the commercialization efforts of the current prominent organ-on-a-chip start-ups.
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Organ-on-chip systems have shown promise sustaining functional microtissues for relatively extended timeframes.
“Recently, organ-on-chip systems—microphysiological systems that combine the use of microfluidics, tissue engineering, and microfabrication tools—have shown promise sustaining functional microtissues for relatively extended timeframes [9,10,11,12].”
From The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors (2019) · cites this paper as [12]
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- Authors
- Zhang, B., & Radisic, M.
- Affiliations
- University of Toronto (CA)
- University Health Network (CA)
- Corresponding author
- Zhang, Boyang
- Radisic, Milica
- Venue
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2017
- Volume
- 17
- Issue
- 14
- Pages
- 2395-2420
- ISSN
- 1473-0189 (ISSN-L)
- 1473-0197
- OpenAlex
- W2621842261
- Cited by
- 437
- References
- 30
- Citations by year
- 2026: 30 · 2025: 42 · 2024: 47 · 2023: 41 · 2022: 55 · 2021: 70 · 2020: 43 · 2019: 58 · 2018: 45 · 2017: 6
- FWCI
- 3.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Lab on a Chip (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (137107_1, 126027_1)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Engineering › Biomedical Engineering › Microfluidic and Capillary Electrophoresis Applications
- Keywords
- organ-on-a-chip, drug discovery, drug screening, human tissue model, commercialization, startups, tissue engineering, cellular communication, microfluidics
- MeSH terms
- Humans, Models, Biological, Microfluidic Analytical Techniques, Drug Discovery, Lab-On-A-Chip Devices
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