Vitamin C and immune cell function in inflammation and cancer

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Functional Polarization of Tumour-Associated Macrophages by Tumour-Derived Lactic Acid

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PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced: MDSC-mediated T cell activation

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HIF-1α is essential for myeloid cell-mediated inflammation

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Metabolic Pathways in Immune Cell Activation and Quiescence

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TET-mediated active DNA demethylation: mechanism, function and beyond

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Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

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JmjC-domain-containing proteins and histone demethylation

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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

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The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

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Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

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The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

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Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

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Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

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HIF1α and metabolic reprogramming in inflammation

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Hypoxia and cancer

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Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

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HIF-1α expression regulates the bactericidal capacity of phagocytes

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Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen

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Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

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The biochemical functions of ascorbic acid

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Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

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The Warburg effect then and now: From cancer to inflammatory diseases

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An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

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Epigenetic regulation of the alternatively activated macrophage phenotype

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A new recommended dietary allowance of vitamin C for healthy young women

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Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

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Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

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Jmjd3 contributes to the control of gene expression in LPS‐activated macrophages

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Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine

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Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes

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Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

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Vitamin C Promotes Maturation of T-Cells

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Vitamin C Facilitates Demethylation of the Foxp3 Enhancer in a Tet-Dependent Manner

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Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation

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Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility

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