The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Endometriosis
Open accessAbstract
A healthy 25-year-old woman presents with worsening dysmenorrhea, new-onset left lower quadrant pain, and dyspareunia. She has regular menstrual cycles, and her last menstrual period was 3 weeks before presentation. How should this patient be evaluated and treated?
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In the citing paper
“Among this population, 12% are estimated to experience endometriosis of nonreproductive organs, referred to as extragenital endometriosis.2–7”
From Thoracic Endometriosis Syndrome: A Review of Diagnosis and Management (2019) · cites this paper as [3]
Experimental — accuracy not yet measuredIn the citing paper
“Biochemical, histological and clinical evidence show that estrogens play a critical role in the pathogenesis of endometriosis”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [3]
In the citing paper
“endometriosis, a common chronic inflammatory disease causing pain and infertility [1,2,3]”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [3]
In the citing paper
“the impact of estradiol (E2), which is known to have proinflammatory and antiapoptotic effects on endometrial cells, especially in ectopic foci [2,3]”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [3]
In the citing paper
“post-operative recurrence is common, because persistent foci not detected at the time of surgery may progress under the influence of circulating estrogens [1,2,3,5,6].”
From Endometriosis and Medical Therapy: From Progestogens to Progesterone Resistance to GnRH Antagonists: A Review (2021) · cites this paper as [3]
In the citing paper
“Wide local excision is the treatment of choice and results in complete resolution of symptoms [2].”
From Giant Abdominal Wall Endometrioma: A Case Report (2021) · cites this paper as [2]
In the citing paper
“Wide local excision is the treatment of choice and results in complete resolution of symptoms [2].”
From Giant Abdominal Wall Endometrioma: A Case Report (2021) · cites this paper as [2]
In the citing paper
“Fertility impairments such as conception delay and infertility are associated with an endometriosis diagnosis (44)”
In the citing paper
“Endometriosis is an estrogen-dependent chronic inflammatory disease (Giudice, 2010)”
From “Waiting for Godot”: a commonsense approach to the medical treatment of endometriosis (2011) · cites this paper as Giudice, 2010
In the citing paper
“Symptoms include dysmenorrhea, dyspareunia (vaginal hyperalgesia), chronic pelvic/abdominal musculoskeletal and other types of severe pain that are often difficult to alleviate without resorting either to hormonal treatments that produce often-intolerable side effects of hypoestrogenicity or to surgery that frequently fails to help [16,21,27,16,48].”
From Endocannabinoid involvement in endometriosis. (2010) · cites this paper as [16]
In the citing paper
“Although it is recognized that both inflammatory and neuropathic mechanisms contribute to endometriosis-associated pains, progress in developing new treatment strategies is impeded by a poor understanding of how the growths, which do not correlate with the pains, contribute to them [16,21,27,48].”
From Endocannabinoid involvement in endometriosis. (2010) · cites this paper as [16]
In the citing paper
“Although it is recognized that both inflammatory and neuropathic mechanisms contribute to endometriosis-associated pains, progress in developing new treatment strategies is impeded by a poor understanding of how the growths, which do not correlate with the pains, contribute to them [16,21,27,48].”
From Endocannabinoid involvement in endometriosis. (2010) · cites this paper as [16]
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Citations
Cites
4 retracted
Laparoscopic surgery for subfertility associated with endometriosis
Jacobson, T. Z., Duffy, J. M., Barlow, D. H., Farquhar, C. M., Koninckx, P. R., & Olive, D. L. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001398.pub2 · Cited by 367
RetractedLaparoscopic surgery for pelvic pain associated with endometriosis
Jacobson, T. Z., Duffy, J. M., Barlow, D. H., Koninckx, P. R., & Garry, R. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001300.pub2 · Cited by 219
RetractedLaparoscopic surgery for subfertility associated with endometriosis
Jacobson, T. Z., Duffy, J. M., Barlow, D. H., Farquhar, C. M., Koninckx, P. R., & Olive, D. L. (2002) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001398 · Cited by 143
RetractedGonadotrophin-releasing hormone analogues for pain associated with endometriosis
Prentice, A., Deary, A., Goldbeck-Wood, S., Farquhar, C., & Smith, S. (1999) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000346 · Cited by 116
RetractedEndocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
Diamanti-Kandarakis, E., Bourguignon, J.-P., Giudice, L. C., Hauser, R., Prins, G. S., Soto, A. M., Zoeller, R. T., & Gore, A. C. (2009) · Endocrine Reviews · doi:10.1210/er.2009-0002 · Cited by 4,585
Self-citationRevised American Society for Reproductive Medicine classification of endometriosis: 1996
American Society for Reproductive Medicine (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81391-x · Cited by 3,018
Bulun, S. E. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804690 · Cited by 1,772
Eskenazi, B., & Warner, M. L. (1997) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(05)70302-8 · Cited by 1,617
ESHRE guideline for the diagnosis and treatment of endometriosis
Kennedy, S., Bergqvist, A., Chapron, C., D’Hooghe, T., Dunselman, G., Greb, R., Hummelshoj, L., Prentice, A., & Saridogan, E. (2005) · Human Reproduction · doi:10.1093/humrep/dei135 · Cited by 1,584
Bulletti, C., Coccia, M. E., Battistoni, S., & Borini, A. (2010) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-010-9436-1 · Cited by 831
Effect of endometriosis on in vitro fertilization
Barnhart, K. T., Dunsmoor-Su, R. F., & Coutifaris, C. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)03112-6 · Cited by 805
Missmer, S. A. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh275 · Cited by 616
Efficacy of Superovulation and Intrauterine Insemination in the Treatment of Infertility
Guzick, D. S., Carson, S. A., Coutifaris, C., Overstreet, J. W., Factor-Litvak, P. R., Steinkampf, M. P., Hill, J. A., Mastroianni, L., Buster, J. E., Nakajima, S. T., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901213400302 · Cited by 521
Delay in the diagnosis of endometriosis: a survey of women from the USA and the UK
Hadfield, R., Mardon, H., Barlow, D., & Kennedy, S. (1996) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a019270 · Cited by 517
Excisional surgery versus ablative surgery for ovarian endometriomata
Hart, R. J., Hickey, M., Maouris, P., & Buckett, W. M. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004992.pub3 · Cited by 470
Berkley, K. J., Rapkin, A. J., & Papka, R. E. (2005) · Science · doi:10.1126/science.1111445 · Cited by 455
Endometriosis: cost estimates and methodological perspective
Simoens, S., Hummelshoj, L., & D'Hooghe, T. (2007) · Human Reproduction Update · doi:10.1093/humupd/dmm010 · Cited by 357
The performance of CA-125 measurement in the detection of endometriosis: a meta-analysis
Mol, B. W. J., Bayram, N., Lijmer, J. G., Wiegerinck, M. A. H. M., Bongers, M. Y., van der Veen, F., & Bossuyt, P. M. M. (1998) · Fertility and Sterility · doi:10.1016/s0015-0282(98)00355-0 · Cited by 355
Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis
Sallam, H. N., Garcia-Velasco, J. A., Dias, S., Arici, A., Abou-Setta, A. M., & Jaafar, S. H. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004635.pub2 · Cited by 349
Hormone treatment of endometriosis: The estrogenthreshold hypothesis
Barbieri, R. L. (1992) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(92)91706-g · Cited by 335
Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis
Brown, J., Crawford, T. J., Allen, C., Hopewell, S., & Prentice, A. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004753.pub4 · Cited by 308
Nerve fibres in peritoneal endometriosis
Tokushige, N., Markham, R., Russell, P., & Fraser, I. S. (2006) · Human Reproduction · doi:10.1093/humrep/del260 · Cited by 299
Vercellini, P., Frontino, G., De Giorgi, O., Pietropaolo, G., Pasin, R., & Crosignani, P. G. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00794-5 · Cited by 289
Harada, T., Momoeda, M., Taketani, Y., Hoshiai, H., & Terakawa, N. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.08.051 · Cited by 289
Endometriosis in association with uterine anomaly
Sanfilippo, J. S., Wakim, N. G., Schikler, K. N., & Yussman, M. A. (1986) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(86)90389-3 · Cited by 270
Pre and post-operative medical therapy for endometriosis surgery
Furness, S., Yap, C., Farquhar, C. M., & Cheong, Y. C. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003678.pub2 · Cited by 257
A prospective study of dietary fat consumption and endometriosis risk
Missmer, S. A., Chavarro, J. E., Malspeis, S., Bertone-Johnson, E. R., Hornstein, M. D., Spiegelman, D., Barbieri, R. L., Willett, W. C., & Hankinson, S. E. (2010) · Human Reproduction · doi:10.1093/humrep/deq044 · Cited by 251
Sutton, C. J. G., Pooley, A. S., Ewen, S. P., & Haines, P. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00403-2 · Cited by 247
Leuprolide Acetate Depot and Hormonal Add-Back in Endometriosis: A 12-Month Study
Hornstein, M. D. (1998) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(97)00620-0 · Cited by 244
Ovulation suppression for endometriosis
Hughes, E., Fedorkow, D. M., Collins, J. A., & Vandekerckhove, P. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000155 · Cited by 242
Progestins for symptomatic endometriosis: a critical analysis of the evidence
Vercellini, P., Cortesi, I., & Crosignani, P. G. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00193-3 · Cited by 229
ACOG Practice Bulletin #51: Chronic Pelvic Pain
(2004) · Obstetrics and Gynecology · doi:10.1097/00006250-200403000-00045 · Cited by 226
The search for genes contributing to endometriosis risk
Montgomery, G. W., Nyholt, D. R., Zhao, Z. Z., Treloar, S. A., Painter, J. N., Missmer, S. A., Kennedy, S. H., & Zondervan, K. T. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn016 · Cited by 211
In utero exposures and the incidence of endometriosis
Missmer, S. A., Hankinson, S. E., Spiegelman, D., Barbieri, R. L., Michels, K. B., & Hunter, D. J. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.04.065 · Cited by 184
Surgical interruption of pelvic nerve pathways for primary and secondary dysmenorrhoea
Proctor, M., Latthe, P., Farquhar, C., Khan, K., & Johnson, N. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001896.pub2 · Cited by 180
Laparoscopy in the diagnosis and management of pelvic pain in adolescents.
GOLDSTEIN, D. P., deCholnoky, C., Emans, S. J., & Leventhal, J. M. (1980) · PubMed · Cited by 161
Gonadotrophin-releasing hormone analogues for endometriosis: bone mineral density
Farmer, J. E., Prentice, A., Breeze, A., Ahmad, G., Duffy, J. M., Watson, A., & Pick, A. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001297 · Cited by 147
Wayne, P. M., Kerr, C. E., Schnyer, R. N., Legedza, A., Savetsky, J. B., Shields, M., Buring, J. E., Davis, R. B., Conboy, L. A., Highfield, E. S., et al. (2008) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2007.07.008 · Cited by 132
Vincent, K., Kennedy, S., & Stratton, P. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.09.056 · Cited by 132
Struthers, R. S., Nicholls, A. J., Grundy, J. S., Chen, T., Jimenez, R., Yen, S. S. C., & Bozigian, H. P. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1695 · Cited by 127
D’Hooghe, T. M., & Hummelshøj, L. (2006) · Human Reproduction · doi:10.1093/humrep/del123 · Cited by 124
Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis
Patwardhan, S., Nawathe, A., Yates, D., Harrison, G., & Khan, K. (2008) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2008.01740.x · Cited by 116
Chen, M. R. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.08.014 · Cited by 107
Diagnosis of endometriosis: pelvic endoscopy and imaging techniques
Brosens, I. A., Puttemans, P., Campo, R., Gordts, S., & Kinkel, K. (2004) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2004.03.002 · Cited by 105
Treatment of pelvic pain associated with endometriosis
(2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.08.057 · Cited by 101
ACOG Committee Opinion #310: Endometriosis in Adolescents
(2005) · Obstetrics and Gynecology · doi:10.1097/00006250-200504000-00058 · Cited by 89
Hormone therapy for endometriosis and surgical menopause
Al Kadri, H., Hassan, S., Al-Fozan, H. M., & Hajeer, A. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005997.pub2 · Cited by 85
Bone Density in Adolescents Treated with a GnRH Agonist and Add-Back Therapy for Endometriosis
DiVasta, A. D., Laufer, M. R., & Gordon, C. M. (2007) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2007.04.008 · Cited by 73
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ACOG Practice Bulletin No. 51. Chronic pelvic pain.
(2004) · PubMed · Cited by 68
Focal pelvic tenderness, pelvic pain and dysmenorrhea in endometriosis.
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Non-steroidal anti-inflammatory drugs for pain in women with endometriosis
Allen, C., Hopewell, S., Prentice, A., & Gregory, D. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004753.pub2 · Cited by 54
Abou-Setta, A. M., Al-Inany, H. G., & Farquhar, C. M. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005072.pub2 · Cited by 45
Evidence may change with more trials: concepts to be kept in mind
Al-Inany, H. G. (2000) · Human Reproduction · doi:10.1093/humrep/15.11.2447-a · Cited by 20
Research works printed but not linked: 17
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- Goldstein DP, 1980, J Reprod Med, 24, 251
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Cited by
Sorted by citations
Endometriosis: pathogenesis and treatment
Vercellini, P., Viganò, P., Somigliana, E., & Fedele, L. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.255 · Cited by 1,940
Bulun, S. E., Yilmaz, B. D., Sison, C., Miyazaki, K., Bernardi, L., Liu, S., Kohlmeier, A., Yin, P., Milad, M., & Wei, J. (2019) · Endocrine Reviews · doi:10.1210/er.2018-00242 · Cited by 844
Cancer-associated mutations in endometriosis without cancer
Anglesio, M. S., Papadopoulos, N., Ayhan, A., Nazeran, T. M., Noë, M., Horlings, H. M., Lum, A., Jones, S., Senz, J., Seckin, T., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1614814 · Cited by 628
Consensus on current management of endometriosis
Johnson, N. P., Hummelshoj, L., for the World Endometriosis Society Montpellier Consortium, Abrao, M. S., Adamson, G. D., Allaire, C., Amelung, V., Andersson, E., Becker, C., Birna Árdal, K. B., et al. (2013) · Human Reproduction · doi:10.1093/humrep/det050 · Cited by 558
Self-citationTreatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist
Taylor, H. S., Giudice, L. C., Lessey, B. A., Abrao, M. S., Kotarski, J., Archer, D. F., Diamond, M. P., Surrey, E., Johnson, N. P., Watts, N. B., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1700089 · Cited by 511
Self-citation
Metadata
- Authors
- Giudice, L. C.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Giudice, Linda C.
- ORCID
- Giudice, Linda C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2010-06-24
- Volume
- 362
- Issue
- 25
- Pages
- 2389-2398
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC3108065
- OpenAlex
- W1513717411
- Cited by
- 1,924
- References
- 54
- Citations by year
- 2026: 101 · 2025: 112 · 2024: 139 · 2023: 151 · 2022: 139 · 2021: 174 · 2020: 200 · 2019: 145 · 2018: 131 · 2017: 123 · 2016: 116 · 2015: 99 · 2014: 87 · 2013: 72 · 2012: 81
- FWCI
- 9.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U54HD055764)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, dysmenorrhea, dyspareunia, pelvic pain, treatment, young women
- MeSH terms
- Dysmenorrhea, Dyspareunia, Endometriosis, Female, Humans, Infertility, Female, Pelvic Pain
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