Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

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A haplotype map of the human genome

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The Future of Genetic Studies of Complex Human Diseases

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Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

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Axonal transection in the lesions of multiple sclerosis

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A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

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A genome-wide association study identifies novel risk loci for type 2 diabetes

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

Scott, L. J., Mohlke, K. L., Bonnycastle, L. L., Willer, C. J., Li, Y., Duren, W. L., Erdos, M. R., Stringham, H. M., Chines, P. S., Jackson, A. U., et al. (2007) · Science · doi:10.1126/science.1142382 · Cited by 2,753

Revised diagnostic criteria for neuromyelitis optica

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ALCAM — Novel multiple sclerosis locus interfering with HLA-DRB1*1501

Wagner, M., Wiśniewski, A., Bilińska, M. M., Pokryszko‐Dragan, A., Nowak, I., Kuśnierczyk, P., & Jasek, M. (2013) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2013.02.015 · Cited by 18

Transmission Distortion in Crohnʼs Disease Risk Gene ATG16L1 Leads to Sex Difference in Disease Association

Liu, L. Y., Schaub, M. A., Sirota, M., & Butte, A. J. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21781 · Cited by 21

The Possible Future Roles for iPSC-Derived Therapy for Autoimmune Diseases

Hew, M., O’Connor, K. D. J., Edel, M. J., & Lucas, M. (2015) · Journal of Clinical Medicine · doi:10.3390/jcm4061193 · Cited by 21

New approaches for predicting T cell–mediated drug reactions: A role for inducible and potentially preventable autoimmunity

Michels, A. W., & Ostrov, D. A. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.06.024 · Cited by 18

Novel somatic single nucleotide variants within the RNA binding protein hnRNP A1 in multiple sclerosis patients

Lee, S., & Levin, M. C. (2014) · F1000Research · doi:10.12688/f1000research.4436.1 · Cited by 18

Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells

McArdel, S. L., Brown, D. R., Sobel, R. A., & Sharpe, A. H. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1600706 · Cited by 18

Immunopathogenesis of multiple sclerosis

Racke, M. K. (2009) · Annals of Indian Academy of Neurology · doi:10.4103/0972-2327.58274 · Cited by 18

Differential expression, and genetic association, of CD58 in Swedish multiple sclerosis patients

Brynedal, B., Bomfim, I. L., Olsson, T. P., Duvefelt, K., & Hillert, J. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904338106 · Cited by 18

CD24 as a genetic modifier of disease progression in multiple sclerosis in Argentinean patients

González, S. J., Rojas, J. I., Redal, M. A., Patrucco, L., Correale, J. D., Argibay, P. F., & Cristiano, E. (2011) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2011.05.032 · Cited by 17

Breakdown of multiple sclerosis genetics to identify an integrated disease network and potential variant mechanisms

Shepard, C. J., Cline, S. G., Hinds, D., Jahanbakhsh, S., & Prokop, J. W. (2019) · Physiological Genomics · doi:10.1152/physiolgenomics.00120.2018 · Cited by 17

A Final Frontier in Environment-Genome Interactions? Integrated, Multi-Omic Approaches to Predictions of Non-Communicable Disease Risk

Noble, A. J., Purcell, R. V., Adams, A. T., Lam, Y. K., Ring, P. M., Anderson, J. R., & Osborne, A. J. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.831866 · Cited by 18

A multiple sclerosis–protective coding variant reveals an essential role for HDAC7 in regulatory T cells

Axisa, P., Yoshida, T. M., Lucca, L. E., Kasler, H. G., Lincoln, M. R., Pham, G. H., Priore, D. D., Carpier, J.-M., Lucas, C. L., Verdin, E. M., et al. (2022) · Science Translational Medicine · doi:10.1126/scitranslmed.abl3651 · Cited by 18

RNF157 attenuates CD4+ T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation

Wang, P., Zhao, J., Tan, Y., Sheng, J., He, S., Chen, Y., Nie, D., You, X., Luo, J., Zhang, Y., et al. (2023) · Theranostics · doi:10.7150/thno.86307 · Cited by 17

Tumor necrosis factor polymorphisms associated with tumor necrosis factor production influence the risk of idiopathic intermediate uveitis.

Atan, D., Heissigerova, J., Kuffová, L., Hogan, A. C., Kilmartin, D. J., Forrester, J. V., Bidwell, J. L., Dick, A. D., & Churchill, A. (2013) · Europe PMC (PubMed Central) · Cited by 17

Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locus

Zouk, H., D'Hennezel, E., Du, X., Ounissi-Benkalha, H., Piccirillo, C. A., & Polychronakos, C. (2014) · Clinical and Experimental Immunology · doi:10.1111/cei.12240 · Cited by 17

Genetic variants in interleukin 7 receptor α chain (IL-7Ra) are associated with multiple sclerosis risk and disability progression in Central European Slovak population

Čierný, D., Hányšová, S., Michalík, J., Kantorová, E., Kurča, E., Škereňová, M., & Lehotský, J. (2015) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2015.03.010 · Cited by 18

Multiple Sclerosis: Are Protective Immune Mechanisms Compromised by a Complex Infectious Background?

Krone, B., & Grange, J. M. (2010) · Autoimmune Diseases · doi:10.4061/2011/708750 · Cited by 17

Chronic Cerebrospinal Vascular Insufficiency Is Not Associated with HLA DRB1*1501 Status in Multiple Sclerosis Patients

Weinstock‐Guttman, B., Zivadinov, R., Cutter, G., Tamaño‐Blanco, M., Marr, K., Badgett, D., Carl, E. M., Elfadil, M., Kennedy, C. L., Benedict, R. H. B., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016802 · Cited by 17

Vitamin D and Multiple Sclerosis

Ho, S.-L., Alappat, L., & Awad, A. B. (2012) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.516034 · Cited by 17

Insufficiently Defined Genetic Background Confounds Phenotypes in Transgenic Studies As Exemplified by Malaria Infection in Tlr9 Knockout Mice

Geurts, N., Martens, E., Verhenne, S., Lays, N., Thijs, G., Magez, S., Cauwe, B., Li, S., Heremans, H., Opdenakker, G., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0027131 · Cited by 17

Multiple sclerosis genetics: Results from meta-analyses of candidate-gene association studies

Tizaoui, K. (2017) · Cytokine · doi:10.1016/j.cyto.2017.10.024 · Cited by 17

Incorporating machine learning approaches to assess putative environmental risk factors for multiple sclerosis

Mowry, E. M., Hedström, A. K., Gianfrancesco, M. A., Shao, X., Schaefer, C. A., Shen, L., Bellesis, K. H., Briggs, F. B. S., Olsson, T. P., Alfredsson, L. S., et al. (2018) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2018.06.009 · Cited by 17

FutureMS cohort profile: a Scottish multicentre inception cohort study of relapsing-remitting multiple sclerosis

Kearns, P. K. A., Martin, S. J., Chang, J. C., Meijboom, R., York, E. N., Chen, Y., Weaver, C., Stenson, A., Hafezi, K., Thomson, S., et al. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-058506 · Cited by 16

Genetic Basis of Inflammatory Demyelinating Diseases of the Central Nervous System: Multiple Sclerosis and Neuromyelitis Optica Spectrum

Ortíz, G. G., Torres-Mendoza, B. M., Ramírez-Jirano, L. J., Márquez-Pedroza, J., Hernández-Cruz, J. J., Mireles-Ramírez, M. A., & Torres-Sánchez, E. D. (2023) · Genes · doi:10.3390/genes14071319 · Cited by 18

IL-7Rα and multiple sclerosis risk

Harley, J. B. (2007) · Nature Genetics · doi:10.1038/ng0907-1053 · Cited by 17

Association between the IL7R T244I polymorphism and multiple sclerosis: a meta-analysis

Zhang, R., Duan, L., Jiang, Y., Zhang, X., Sun, P., Li, J., Zhang, M., Tang, G., Wang, X., & Li, X. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0654-5 · Cited by 17

TLR4 haplotypes in multiple sclerosis: A case-control study in the Spanish population

Urcelay, E., Blanco‐Kelly, F., Heras, V. D. L., de la Concha, E. G., Arroyo, R., & Martínez, A. (2007) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2007.10.001 · Cited by 16

Susceptibility variants in the CD58 gene locus point to a role of microRNA-548ac in the pathogenesis of multiple sclerosis

Hecker, M., Fitzner, B., Blaschke, J., Blaschke, P., & Zettl, U. K. (2014) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2014.10.002 · Cited by 17

SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3

del Río, R., Noubade, R., Subramanian, M., Saligrama, N., Diehl, S. A., Rincón, M., & Teuscher, C. (2008) · Genes and Immunity · doi:10.1038/sj.gene.6364455 · Cited by 17

Interleukin 18 Receptor 1 expression distinguishes patients with multiple sclerosis

Gillett, A., Hedreul, M. T., Khademi, M., Espinosa, A., Beyeen, A. D., Jagodic, M., Kockum, I. S., Harris, R. A., & Olsson, T. P. (2010) · Multiple Sclerosis Journal · doi:10.1177/1352458510364634 · Cited by 16

Susceptibility Genes for Multiple Sclerosis Identified in a Gene-Based Genome-Wide Association Study

Lin, X., Deng, F., Lu, X., & Lei, S. (2015) · Journal of Clinical Neurology · doi:10.3988/jcn.2015.11.4.311 · Cited by 18

Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis

Sombekke, M. H., Arteta, D., van de Wiel, M. A., Crusius, J. B. A., Tejedor, D., Killestein, J., Martínez, A., Peña, A. S., Polman, C. H., & Uitdehaag, B. M. J. (2010) · Multiple Sclerosis Journal · doi:10.1177/1352458510364633 · Cited by 17

Unrecognized sequence homologies may confound genome-wide association studies

Galichon, P., Mesnard, L., Hertig, A., Stengel, B., & Rondeau, É. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks169 · Cited by 17

HLA-DRB1*1501 intensifies the impact of IL-6 promoter polymorphism on the susceptibility to multiple sclerosis in an Iranian population

Shahbazi, M., Ebadi, H., Fathi, D., Roshandel, D., Mohamadhosseni, M., Tahmasebi, A., Shahbazi, S., Zamani, M., & Rashidbaghan, A. (2010) · Multiple Sclerosis Journal · doi:10.1177/1352458510376177 · Cited by 17

The association of HLA-DRB1 and HLA-DQB1 alleles with genetic susceptibility to multiple sclerosis in the Slovak population

Michalík, J., Čierný, D., Kantorová, E., Kantárová, D., Javor, J., Párnická, Z., Kurča, E., Dobrota, D., & Lehotský, J. (2015) · Neurological Research · doi:10.1080/01616412.2015.1115212 · Cited by 17

Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity

Bearoff, F. M., del Río, R., Case, L. K., Dragon, J. A., Nguyen-Vu, T., Lin, C.-Y., Blankenhorn, E. P., Teuscher, C., & Krementsov, D. N. (2016) · Genes and Immunity · doi:10.1038/gene.2016.37 · Cited by 16

EPIGENETIC MECHANISMS IN MULTIPLE SCLEROSIS.

Gacias, M., & Casaccia, P. (2014) · PubMed · Cited by 17

A Genome-Wide Association Study Primer for Clinicians

Wang, T., & Wang, H. (2009) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/s1028-4559(09)60265-5 · Cited by 17

Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair

Bieber, A. J., Suwansrinon, K., Kerkvliet, J. G., Zhang, W., Pease, L. R., & Rodriguez, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906589107 · Cited by 18

The developing mosaic of autoimmune disease risk

Maier, L. M., & Hafler, D. A. (2008) · Nature Genetics · doi:10.1038/ng0208-131 · Cited by 17

Shared susceptibility variations in autoimmune diseases: a brief perspective on common issues

Seldin, M. F., & Amos, C. I. (2009) · Genes and Immunity · doi:10.1038/gene.2008.92 · Cited by 17

Bioinformatics approach to identifying molecular biomarkers and networks in multiple sclerosis

Satoh, J. (2010) · Clinical and Experimental Neuroimmunology · doi:10.1111/j.1759-1961.2010.00013.x · Cited by 16

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Smits, D. J., Dekker, J., Schot, R., Tabarki, B. M., Alhashem, A. M., Demmers, J., Dekkers, D. H. W., Romito, A., van der Spek, P. J., van Ham, T. J., et al. (2022) · Human Genetics · doi:10.1007/s00439-022-02511-3 · Cited by 15

The Orally Available, Synthetic Ether Lipid Edelfosine Inhibits T Cell Proliferation and Induces a Type I Interferon Response

Abramowski, P., Otto, B., & Martinꝉ, R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0091970 · Cited by 15

The Genetic and Environmental Bases of Complex Human-Disease: Extending the Utility of Twin-Studies

Goodin, D. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047875 · Cited by 16

Genomic Binding Sites and Biological Effects of the Vitamin D: VDR Complex in Multiple Sclerosis

Kálmán, B., & Toldy, E. (2014) · NeuroMolecular Medicine · doi:10.1007/s12017-014-8301-2 · Cited by 16

Physiopathologie de la sclérose en plaques

Brassat, D. (2010) · La Presse Médicale · doi:10.1016/j.lpm.2009.12.001 · Cited by 20

Association of Multiple Sclerosis Susceptibility Variants and Early Attack Location in the CNS

Mowry, E. M., Carey, R. F., Quilez, M. R. B., Pelletier, J., Duquette, P., Villoslada, P., Irina Malikova, A., Roger, É., Kinkel, R. P., McDonald, J., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075565 · Cited by 16

Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array

Dankowski, T., Buck, D., Andlauer, T. F. M., Antony, G., Bayas, A., Bechmann, L., Berthele, A., Bettecken, T., Chan, A., Franke, A., et al. (2015) · Genetic Epidemiology · doi:10.1002/gepi.21933 · Cited by 18

The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis.

Fard, N. A., Azizi, G., & Mirshafiey, A. (2016) · PubMed Central · Cited by 16

Modificaciones epigenéticas en neurología: alteraciones en la metilación del ADN en la esclerosis múltiple

Zulet, M. I., Fontes, L. P., Blanco, T. A., Bescos, F. L., & Mendióroz, M. (2015) · Neurología · doi:10.1016/j.nrl.2015.03.011 · Cited by 16

Dynamic demethylation of theIL2RApromoter duringin vitroCD4+ T cell activation in association with IL2RA expression

Belot, M., Castell, A., Fur, S. L., & Bougneres, P. F. (2018) · Epigenetics · doi:10.1080/15592294.2018.1469893 · Cited by 16

Genetic Association and Altered Gene Expression of CYBB in Multiple Sclerosis Patients

Cardamone, G., Paraboschi, E. M., Soldà, G., Duga, S., Saarela, J., & Asselta, R. (2018) · Biomedicines · doi:10.3390/biomedicines6040117 · Cited by 16

Lung cancer risk in patients with multiple sclerosis: a Mendelian randomization analysis

Ge, F., Huo, Z., Li, C., Wang, R., Wang, R., Liu, Y., Chen, J., Lu, Y., Wen, Y., Jiang, Y., et al. (2021) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2021.102927 · Cited by 15

The Double-Edged Sword of Autoimmunity: Lessons from Multiple Sclerosis

Hestvik, A. L. K. (2010) · Toxins · doi:10.3390/toxins2040856 · Cited by 16

Association between Protective and Deleterious HLA Alleles with Multiple Sclerosis in Central East Sardinia

Pastorino, R., Menni, C., Barca, M., Foco, L., Saddi, V., Gazzaniga, G., Ferrai, R., Mascaretti, L. G., Dudbridge, F., Berzuini, C., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006526 · Cited by 16

Nonparametric Methods for Molecular Biology

Wittkowski, K. M., & Song, T. (2009) · Methods in molecular biology · doi:10.1007/978-1-60761-580-4_2 · Cited by 17

Association of IL4 and IL4R polymorphisms with multiple sclerosis susceptibility in Caucasian population: A meta-analysis

Zhang, Z., Wang, L., Sun, X. Y., Zhang, L., & Lu, L.-Y. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.02.049 · Cited by 16

Abnormal CD25 expression on hematopoietic cells in myelodysplastic syndromes

Liu, P., Jiang, H., Che, M., Fu, R., Wang, H., Li, L., Zhang, W., Tao, J., Gao, S., & Shao, Z. (2017) · Leukemia Research · doi:10.1016/j.leukres.2017.11.010 · Cited by 16

In silico identification of protein targets for chemical neurotoxins using ToxCast in vitro data and read-across within the QSAR toolbox

Chushak, Y. G., Shows, H. W., Gearhart, J. M., & Pangburn, H. A. (2018) · Toxicology Research · doi:10.1039/c7tx00268h · Cited by 16

Lack of replication of KIF1B gene in an Italian primary progressive multiple sclerosis cohort

Boneschi, F. M., Esposito, F., Scalabrini, D., Fenoglio, C., Rodegher, M., Brambilla, P., Colombo, B., Ghezzi, A., Capra, R., Collimedaglia, L., et al. (2010) · European Journal of Neurology · doi:10.1111/j.1468-1331.2009.02925.x · Cited by 16

ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response

Doi, K., Fujimoto, T., Okamura, T., Ogawa, M., Tanaka, Y., Mototani, Y., Goto, M., Ota, T., Matsuzaki, H., Kuroki, M., et al. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.07.065 · Cited by 16

Fungal Infection in Patients with Multiple Sclerosis

Ramos, M., Pisa, D., Molina, S., Rábano, A., Juarranz, Á., & Carrasco, L. (2008) · The Open Mycology Journal · doi:10.2174/1874437000802010022 · Cited by 16

HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study

Liguori, M., Healy, B. C., Glanz, B. I., Khoury, S. J., Moscufo, N., Weiner, H. L., Jager, P. L. D., & Guttmann, C. R. G. (2010) · Genes and Immunity · doi:10.1038/gene.2010.58 · Cited by 16

Monoclonal antibody treatments for multiple sclerosis

ROSE, J. W., Foley, J. F., & Carlson, N. G. (2008) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-008-0065-3 · Cited by 16

Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset

Khankhanian, P., Gourraud, P., Caillier, S. J., Santaniello, A., Hauser, S. L., Baranzini, S. E., & Oksenberg, J. R. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-626 · Cited by 17

Cytokines Genes Polymorphisms and Risk of Multiple Sclerosis

Izad, M., Vodjgani, M., Niknam, M. H., Amirzargar, A., Heidari, A. B., Shahbeigi, S., & Keramatipour, M. (2010) · The American Journal of the Medical Sciences · doi:10.1097/maj.0b013e3181cef1a1 · Cited by 15

A Candidate Gene Approach of the Calcineurin Pathway To Identify Variants Associated with Clinical Outcomes in Renal Transplantation

Pouché, L., Koitka, M., Stojanova, J., Woillard, J., Monchaud, C., Villeneuve, C., Essig, M., Abraham, J., Meur, Y. L., Rérolle, J. P., et al. (2016) · Pharmacogenomics · doi:10.2217/pgs.15.181 · Cited by 17

Meta-analysis of theIL23RandIL12Bpolymorphisms in multiple sclerosis

Huang, J., Yang, Y., Zhou, F.-M., Liang, Z., Kang, M., Kuang, Y., & Li, F. (2015) · International Journal of Neuroscience · doi:10.3109/00207454.2015.1007508 · Cited by 15

Inflammation and susceptibility to neurodegeneration: The use of unbiased genetics to decipher critical regulatory pathways

Piehl, F., & Olsson, T. P. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.08.031 · Cited by 15

The Missing Heritability Paradigm: A Dramatic Resurgence of the GIGO Syndrome in Genetics

Génin, E., & Clerget‐Darpoux, F. (2015) · Human Heredity · doi:10.1159/000370327 · Cited by 19

Recent advances of long noncoding RNAs involved in the development of multiple sclerosis

Li, Q., Lei, W., Chen, C., & Guo, W. Y. (2020) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(20)30003-0 · Cited by 15

Genetic susceptibility to multiple sclerosis in African Americans

Goodin, D. S., Oksenberg, J. R., Douillard, V., Gourraud, P., & Vince, N. (2021) · PLoS ONE · doi:10.1371/journal.pone.0254945 · Cited by 15

PSI: The Dutch Academic Infrastructure for shared biobanks for translational research.

Talmon, J. L., Ros', M. G., & Legemate, D. A. (2008) · PubMed Central · Cited by 15

The Genetics of Multiple Sclerosis

Hillert, J. A. (2009) · Results and problems in cell differentiation · doi:10.1007/400_2009_13 · Cited by 19

Contributing factors in multiple sclerosis and the female sex bias

Khalid, R. (2014) · Immunology Letters · doi:10.1016/j.imlet.2014.09.004 · Cited by 15

Disease Modifying Therapy in Multiple Sclerosis

Williams, U. E., Oparah, S. K., & Philip-Ephraim, E. E. (2014) · International Scholarly Research Notices · doi:10.1155/2014/307064 · Cited by 15

Missing links in multiple sclerosis etiology. A working connecting hypothesis

Soulillou, J. (2013) · Medical Hypotheses · doi:10.1016/j.mehy.2013.01.036 · Cited by 15

Genetic Correlations of Brain Lesion Distribution in Multiple Sclerosis: An Exploratory Study

Sombekke, M. H., Vellinga, M. M., Uitdehaag, B. M. J., Barkhof, F., Polman, C. H., Arteta, D., Tejedor, D., Martinez, A., Crusius, J. B. A., Peña, A. S., et al. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2352 · Cited by 15

Association between the IL7R T244I polymorphism and multiple sclerosis risk: a meta analysis

Wu, S., Liu, Q., Zhu, J., Wang, M.-R., Li, J., & Sun, M.-G. (2016) · Neurological Sciences · doi:10.1007/s10072-016-2608-8 · Cited by 15

Therapeutic Application of Monoclonal Antibodies in Multiple Sclerosis

Orthmann‐Murphy, J. L., & Calabresi, P. A. (2016) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.547 · Cited by 15

Design and Synthesis of Non-Peptide Mimetics Mapping the Immunodominant Myelin Basic Protein (MBP83–96) Epitope to Function as T-Cell Receptor Antagonists

Yannakakis, M.-P., Simal, C., Tzoupis, H., Rodi, M., Dargahi, N., Prakash, M. D., Mouzaki, Α., Platts, J. A., Apostolopoulos, V., & Tselios, T. V. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061215 · Cited by 15

Investigating multiple sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci

Fazia, T., Pastorino, R., Foco, L., Han, L., Abney, M., Beecham, A. H., Hadjixenofontos, A., Guo, H., Gentilini, D., Papachristou, C., et al. (2017) · Multiple Sclerosis Journal · doi:10.1177/1352458517732841 · Cited by 15

Epigenetic changes in neurology: DNA methylation in multiple sclerosis

Zulet, M. I., Fontes, L. P., Blanco, T. A., Bescos, F. L., & Mendióroz, M. (2017) · Neurología (English Edition) · doi:10.1016/j.nrleng.2015.03.020 · Cited by 15

Soluble IL-7Rα/sCD127 in Health, Disease, and Its Potential Role as a Therapeutic Agent

Barros, P. O., Berthoud, T. K., Aloufi, N., & Angel, J. B. (2021) · ImmunoTargets and Therapy · doi:10.2147/itt.s264149 · Cited by 15

Planning a genome-wide association study: Points to consider

Hakonarson, H. H., & Grant, S. F. A. (2011) · Annals of Medicine · doi:10.3109/07853890.2011.573803 · Cited by 14

Clonal composition of neuroantigen-specific CD8+ and CD4+ T-cells in multiple sclerosis

Biegler, B. W., Yan, S. X., Ortega, S. B., Tennakoon, D. K., Racke, M. K., & Karandikar, N. J. (2011) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2011.02.001 · Cited by 14

Association of CD58 Polymorphism with Multiple Sclerosis and Response to Interferon ß Therapy in A Subset of Iranian Population.

Torbati, S., Karami, F., Ghaffarpour, M., & Zamani, M. (2015) · Europe PMC (PubMed Central) · doi:10.22074/cellj.2015.505 · Cited by 14

Human leucocyte antigen class I and II imputation in a multiracial population

Kuniholm, M. H., Xie, X., Anastos, K., Xue, X., Reimers, L., French, A. L., Gange, S. J., Kassaye, S., Kovács, A., Wang, T., et al. (2016) · International Journal of Immunogenetics · doi:10.1111/iji.12292 · Cited by 15

Gene variation in IL-7 receptor (IL-7R)α affects IL-7R response in CD4+ T cells in HIV-infected individuals

Hartling, H. J., Ryder, L. P., Ullum, H., Ødum, N., & Nielsen, S. D. (2017) · Scientific Reports · doi:10.1038/srep42036 · Cited by 15

Genome-Wide Multiple Sclerosis Association Data and Coagulation

Starza, S. L., Ferraldeschi, M., Buscarinu, M. C., Romano, S., Fornasiero, A., Mechelli, R., Umeton, R., Ristori, G., & Salvetti, M. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00095 · Cited by 13

Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms

Keindl, M., Fedotkina, O., du Plessis, E., Jain, R., Bergum, B., Jensen, T. M., Møller, C. L., Falhammar, H., Nyström, T., Catrina, S., et al. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.575469 · Cited by 14

Cannabinoid-Based Medicines and Multiple Sclerosis

Manera, C., & Bertini, S. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-57369-0_8 · Cited by 15

Current and Future Immunotherapies for Multiple Sclerosis.

Bourque, J., & Hawiger, D. (2021) · PubMed Central · Cited by 14

Predicting Peptide Binding Affinities to MHC Molecules Using a Modified Semi-Empirical Scoring Function

Liao, W. W. P., & Arthur, J. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025055 · Cited by 14

Tibetan Medical Interpretation of Myelin Lipids and Multiple Sclerosis

Husted, C. A., & Dhondup, L. (2009) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1393.022 · Cited by 14

Specific aspects of modern life for people with multiple sclerosis: considerations for the practitioner

Oreja‐Guevara, C., Wiendl, H., Kieseier, B. C., Airas, L. M., & for the NeuroNet Study Group (2013) · Therapeutic Advances in Neurological Disorders · doi:10.1177/1756285613501575 · Cited by 14

Association of interleukin 7 receptor gene polymorphism rs6897932 with multiple sclerosis patients in Khuzestan.

Majdinasab, N., Behbahani, M. H., Galehdari, H., & Mohaghegh, M. (2014) · Europe PMC (PubMed Central) · Cited by 14

Family Analysis of Linkage and Association of HLA-DRB1, CTLA4, TGFB1, IL4, CCR5, RANTES, MMP9 and TIMP1 Gene Polymorphisms with Multiple Sclerosis

Макарычева, О. Ю., Tsareva, E., Sudomoina, M. A., Кулакова, О. Г., Titov, B. V., Быкова, О. В., Гольцова, Н. В., Kuzenkova, L. M., Бойко, А. Н., & Favorova, O. O. (2011) · Acta Naturae · doi:10.32607/20758251-2011-3-1-85-92 · Cited by 14

HLA-DRB1*14 is a protective allele for multiple sclerosis in an admixed Colombian population

Toro, J., Cuéllar-Giraldo, D. F., Diaz‐Cruz, C., Burbano, L. E., Guío‐Sánchez, C., Reyes, S., Cortés-Muñoz, F., Cárdenas‐Robledo, S., Narváez, D. M., Cárdenas, W. A., et al. (2015) · Neurology Neuroimmunology & Neuroinflammation · doi:10.1212/nxi.0000000000000192 · Cited by 14

News in brief

(2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70214-4

Interleukin 7 receptor α chain ( IL7R ) shows allelic and functional association with multiple sclerosis

for the Multiple Sclerosis Genetics Group, Gregory, S. G., Schmidt, S., Seth, P., Oksenberg, J. R., Hart, J., Prokop, A., Caillier, S. J., Ban, M., Goris, A., et al. (2007) · Nature Genetics · doi:10.1038/ng2103 · Cited by 657

Risk alleles for multiple sclerosis in multiplex families

D’Netto, M. J., Ward, H., Morrison, K., Ramagopalan, S. V., Dyment, D. A., DeLuca, G. C., Handunnetthi, L., Sadovnick, A. D., & Ebers, G. C. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a92c25 · Cited by 62

Decoding multiple sclerosis: an update on genomics and future directions

Oksenberg, J. R. (2013) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2013.865867 · Cited by 66

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility

Zuvich, R. L., McCauley, J. L., Oksenberg, J. R., Sawcer, S. J., Jager, P. L. D., Aubin, C., Cross, A. H., Piccio, L. M., Aggarwal, N. T., Evans, D. A., et al. (2010) · Human Genetics · doi:10.1007/s00439-010-0789-4 · Cited by 65