Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

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Reassessing the amyloid cascade hypothesis of Alzheimer's disease

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Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1

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The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

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The Roles of Cyclin-dependent Kinase 5 and Glycogen Synthase Kinase 3 in Tau Hyperphosphorylation

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Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

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The ubiquitin‐proteasome system in Alzheimer's disease

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Reversal of Alzheimer’s-like pathology and behavior in human APP transgenic mice by mutation of Asp664

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The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

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NMDA Receptor Subunit NR2A Is Required for Rapidly Acquired Spatial Working Memory But Not Incremental Spatial Reference Memory

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Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

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Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD).

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The C‐terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome‐dependent mechanism distinct from γ‐secretase

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Overexpression of wild-type human APP in mice causes cognitive deficits and pathological features unrelated to Aβ levels

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Objective Assessment of the Degree of Dementia by Means of EEG

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Multiple Roles for Glycogen Synthase Kinase-3 as a Drug Target in Alzheimers Disease

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Chronic lithium treatment magnifies learning in rats

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Mutations in APP have independent effects on Aβ and CTFγ generation

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Alterations in β-amyloid production and deposition in brain regions of two transgenic models

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Fe65 Is Not Involved in the Platelet-derived Growth Factor-induced Processing of Alzheimer's Amyloid Precursor Protein, Which Activates Its Caspase-directed Cleavage

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Amyloid Beta: Structure, Biology and Structure-Based Therapeutic Development

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Alzheimer Mechanisms and Therapeutic Strategies

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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

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Alzheimer's disease: experimental models and reality

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Not just amyloid: physiological functions of the amyloid precursor protein family

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Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease

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NAD ⁺ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

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Synapses and Alzheimer's Disease

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Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network

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GSK‐3 in Neurodegenerative Diseases

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Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease

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The keystone of Alzheimer pathogenesis might be sought in Aβ physiology

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Molecular and cellular aspects of age-related cognitive decline and Alzheimer’s disease

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Current Anti-Amyloid-β Therapy for Alzheimer’s Disease Treatment: From Clinical Research to Nanomedicine

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β-amyloid: The known unknowns

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Coenzyme Q10 Reduces β-Amyloid Plaque in an APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease

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Progress toward valid transgenic mouse models for Alzheimer’s disease

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