Stimulus repetition modulates gamma-band synchronization in primate visual cortex
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Significance: When a visual stimulus repeats multiple times, visual cortical neurons show decreasing firing rate responses, yet neither perception nor stimulus-related behavior is compromised. We show that stimulus repetition leads to increased neuronal gamma-band (∼40–90 Hz) synchronization within and between early and higher visual areas. The enhanced gamma-band synchronization likely maintains effective stimulus signaling in the face of dwindling firing rates. We also show that synchronization to the gamma rhythm increases for spikes in general and for those of putative interneurons, whereas it decreases for spikes of putative excitatory neurons if they are not strongly stimulus-driven. Thus, inhibitory interneurons might create increasingly precise gamma-band synchronization, and thereby prune the stimulus representation by pyramidal cells to be sparser and more efficient.
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In previous studies where stimulus repetition was not behaviorally relevant, gamma-band power and synchronization in visual cortex increased with repetition.
“In previous studies where stimulus repetition was not behaviorally relevant, gamma-band power and synchronization in visual cortex increased with repetition, whereas we observed decreases (48, 49).”
From Layer and rhythm specificity for predictive routing (2020) · cites this paper as [48]
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- Authors
- Brunet, N. M., Bosman, C. A., Vinck, M., Roberts, M., Oostenveld, R., Desimone, R., De Weerd, P., & Fries, P.
- Affiliations
- Radboud University Nijmegen (NL)
- Max Planck Society (DE)
- McGovern Institute for Brain Research (US)
- Donders Institute for Brain, Cognition, and Behaviour, Radboud University Nijmegen, 6525 EN Nijmegen, The Netherlands;
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2014-02-19
- Volume
- 111
- Issue
- 9
- Pages
- 3626-3631
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC3948273
- OpenAlex
- W2042775785
- Cited by
- 130
- References
- 40
- Citations by year
- 2026: 5 · 2025: 8 · 2024: 10 · 2023: 8 · 2022: 11 · 2021: 6 · 2020: 14 · 2019: 12 · 2018: 6 · 2017: 8 · 2016: 21 · 2015: 13 · 2014: 8
- FWCI
- 9.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UvA-DARE (University of Amsterdam) (publishedVersion)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- UvA-DARE (University of Amsterdam) (submittedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek (452-03-344)
- National Eye Institute (R01EY017292)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- gamma-band synchronization, stimulus repetition, visual cortex, macaque, area V1, area V4, neuronal firing rate, multi-unit activity, single-unit activity, pyramidal neurons, interneurons, electrophysiology
- MeSH terms
- Action Potentials, Adaptation, Physiological, Animals, Electroencephalography, Macaca mulatta, Male, Photic Stimulation, Visual Cortex, Visual Perception, Principal Component Analysis, Brain Waves
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