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Cited by 90

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The Intracellular Domain of the Low Density Lipoprotein Receptor-related Protein Modulates Transactivation Mediated by Amyloid Precursor Protein and Fe65

Kinoshita, Ayae, Shah, Tejal, Tangredi, Michelle M., Strickland, Dudley K., Hyman, Bradley T.·2003·Journal of Biological Chemistry
DOI 10.1074/jbc.m306403200
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Crossref · 10.1074/jbc.m306403200

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2 of 2 references verified0 citation errors · 0 not checkable

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  • γ-Secretase cleavage of LRP leads to release of the LRP intracellular domain (LRP-ICD), which can translocate to the nucleus and interact with Tip60.

    “Furthermore, and as with APP, ␥-secretase cleavage of LRP leads to release of the LRP intracellular domain (LRP-ICD), which can translocate to the nucleus and interact with Tip60 (27,28).”

    From The Low Density Lipoprotein Receptor-related Protein (LRP) Is a Novel β-Secretase (BACE1) Substrate (2005) · cites this paper as [27]

    The Discussion says LRP cleavage releases its intracellular domain, which translocates to the nucleus; Fig. 5 reports close interaction with Tip60 there. The Discussion describes γ-secretase as the probable cause of cleavage, so the citing sentence states that mechanism more definitively than the source does. Page numbers are unavailable in our copy. (LLM, conf=0.85)

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  • The multiple alternative functions assigned to LRP1 in AD complicate interpretation of the available experimental data.

    “Likely, the multiple alternative functions assigned to this receptor in AD, including intracellular APP transport (Ulery et al., 2000; Pietrzik et al., 2002), blockade of APP signaling (Kinoshita et al., 2003), or Aβ shunt across the blood-brain-barrier (Deane et al., 2004) complicate interpretation of the available experimental data.”

    From The Pro-Neurotrophin Receptor Sortilin Is a Major Neuronal Apolipoprotein E Receptor for Catabolism of Amyloid-β Peptide in the Brain (2013) · cites this paper as Kinoshita et al., 2003

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Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 34

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Metadata

Authors
Kinoshita, A., Shah, T., Tangredi, M. M., Strickland, D. K., & Hyman, B. T.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2003-10
Volume
278
Issue
42
Pages
41182-41188
ISSN
0021-9258
DOI
10.1074/jbc.m306403200
Cited by
90
References
2
Language
en
Licence

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