Neuropsychological functioning in severe acute respiratory disorders caused by the coronavirus: implications for the current COVID-19 pandemic.
Abstract
Objective: The coronavirus class of respiratory viruses - including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19) - has been associated with central nervous system (CNS) disease. In fact, multiple mechanisms of CNS involvement have been proposed, making it difficult to identify a unitary syndrome that can be the focus of clinical work and research. Neuropsychologists need to understand the potential cognitive and psychological sequelae of COVID-19 and the impact of the interventions (e.g., ICU, ventilation) that have been used in treating patients with severe forms of the illness.Method: We briefly review the literature regarding the neurological and neuropsychological effects of similar coronaviruses, the limited information that has been published to date on COVID-19, and the literature regarding the long-term cognitive and psychological effects of undergoing treatment in the intensive care unit (ICU).Results: We discuss the roles that neuropsychologists can play in assessing and treating the cognitive difficulties and psychiatric symptoms described.Conclusions: At this time, the mechanisms, correlates, and effects of COVID-19 are poorly understood, but information gleaned from the literature on similar viruses and utilized interventions should help inform neuropsychologists as they begin to work with this population.
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The association between IQCODE and TICS-40 scores was analyzed to ensure consistency of the two cognitive assessments.
“The association between IQCODE and TICS-40 scores was analyzed to ensure the consistency of the 2 cognitive assessments verified in previous studies.20,21”
From One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study (2022) · cites this paper as [20]
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- Authors
- Rabinovitz, B., Jaywant, A., & Fridman, C. B.
- Affiliations
- NewYork–Presbyterian Hospital (US)
- Corresponding author
- Fridman, Chaya B.
- ORCID
- Jaywant, Abhishek
- Venue
- The Clinical Neuropsychologist
- Publisher
- Informa UK Limited
- Published
- 2020-09-09
- Volume
- 34
- Issue
- 7-8
- Pages
- 1453-1479
- ISSN
- 0920-1637 (ISSN-L)
- 1385-4046
- 1744-4144
- OpenAlex
- W3083936504
- Cited by
- 46
- References
- 103
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 9 · 2022: 16 · 2021: 15 · 2020: 1
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Clinical Neuropsychologist (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (P50CA097274)
- Topics
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Keywords
- COVID-19 pandemic, SARS-CoV-2, neuropsychological performance, cognitive sequelae, psychiatric symptoms, central nervous system involvement, intensive care unit, mechanical ventilation, neuropsychological assessment, neuropsychological intervention, long-term cognitive outcomes
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Mental Disorders, Humans, Neuropsychological Tests, Pneumonia, Viral, Coronavirus Infections, Pandemics
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