Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T. B., Oukka, M., Weiner, H. L., & Kuchroo, V. K. (2006) · Nature · doi:10.1038/nature04753 · Cited by 6,992 · see citing works

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Park, J., Adoro, S., Guinter, T. I., Erman, B., Alag, A., Catálfamo, M., Kimura, M. Y., Cui, Y., Lucas, P. J., Gress, R. E., et al. (2010) · Nature Immunology · doi:10.1038/ni.1840 · Cited by 5,835 · see citing works

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., & Toda, M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.3.1151 · Cited by 5,608 · see citing works

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Curiel, T. J., Coukos, G., Zou, L., Alvarez, X., Cheng, P., Mottram, P., Evdemon-Hogan, M., Conejo-Garcia, J. R., Zhang, L., Burow, M., et al. (2004) · Nature Medicine · doi:10.1038/nm1093 · Cited by 5,151 · see citing works

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3

Chen, W., Jin, W., Hardegen, N. J., Lei, K.-J., Li, L., Marinos, N. J., McGrady, G., & Wahl, S. M. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030152 · Cited by 4,678 · see citing works

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivanov, I. I., Atarashi, K., Manel, N., Brodie, E. L., Shima, T., Karaoz, U., Wei, D., Goldfarb, K. C., Santee, C. A., Lynch, S. V., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.033 · Cited by 4,554 · see citing works

Induction of Colonic Regulatory T Cells by Indigenous <i>Clostridium</i> Species

Atarashi, K., Tanoue, T., Shima, T., Imaoka, A., Kuwahara, T., Momose, Y., Cheng, G., Yamasaki, S., Saito, T., Ohba, Y., et al. (2011) · Science · doi:10.1126/science.1198469 · Cited by 3,752 · see citing works

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Bennett, C. L., Christie, J., Ramsdell, F., Brunkow, M., Ferguson, P., Whitesell, L., Kelly, T., Saulsbury, F., Chance, P., & Ochs, H. (2001) · Nature Genetics · doi:10.1038/83713 · Cited by 3,576 · see citing works

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism

Coombes, J. L., Siddiqui, K. R. R., Arancibia-Cárcamo, C. V., Hall, J. A., Sun, C., Belkaid, Y., & Powrie, F. M. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070590 · Cited by 2,708 · see citing works

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

Thornton, A. M., & Shevach, E. M. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.2.287 · Cited by 2,637 · see citing works

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B. W., Clark, L. B., Yasayko, S.-A., Wilkinson, J. E., Galas, D. J., Ziegler, S. F., & Ramsdell, F. (2001) · Nature Genetics · doi:10.1038/83784 · Cited by 2,628 · see citing works

Inducible Foxp3 ⁺ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

Round, J. L., & Mazmanian, S. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909122107 · Cited by 2,233 · see citing works

Reciprocal T _H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid

Mucida, D., Park, Y., Kim, G., Turovskaya, O., Scott, I., Kronenberg, M., & Cheroutre, H. (2007) · Science · doi:10.1126/science.1145697 · Cited by 1,982 · see citing works

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

Wildin, R. S., Ramsdell, F., Peake, J., Faravelli, F., Casanova, J., Buist, N. R. M., Levy‐Lahad, E., Mazzella, M., Goulet, O., Perroni, L., et al. (2001) · Nature Genetics · doi:10.1038/83707 · Cited by 1,916 · see citing works

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

Sun, C., Hall, J. A., Blank, R. B., Bouladoux, N. J., Oukka, M., Mora, J. R., & Belkaid, Y. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20070602 · Cited by 1,880 · see citing works

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

Zhou, L., Lopes, J. E., Chong, M. M. W., Ivanov, I. I., Min, R., Victora, G. D., Shen, Y., Du, J., Rubtsov, Y. P., Rudensky, A. Y., et al. (2008) · Nature · doi:10.1038/nature06878 · Cited by 1,859 · see citing works

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Kim, J. M., Rasmussen, J. P., & Rudensky, A. Y. (2006) · Nature Immunology · doi:10.1038/ni1428 · Cited by 1,827 · see citing works

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

Takahashi, T., Kuniyasu, Y., Toda, M., Sakaguchi, N., Itoh, M., Iwata, M., Shimizu, J., & Sakaguchi, S. (1998) · International Immunology · doi:10.1093/intimm/10.12.1969 · Cited by 1,566 · see citing works

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

Thornton, A. M., Korty, P. E., Tran, D. Q., Wohlfert, E. A., Murray, P. E., Belkaid, Y., & Shevach, E. M. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0904028 · Cited by 1,382 · see citing works

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

Zhou, X., Bailey-Bucktrout, S. L., Jeker, L. T., Peñaranda, C., Martínez‐Llordella, M., Ashby, M., Nakayama, M., Rosenthal, W. L., & Bluestone, J. A. (2009) · Nature Immunology · doi:10.1038/ni.1774 · Cited by 1,374 · see citing works

Natural versus adaptive regulatory T cells

Bluestone, J. A., & Abbas, A. K. (2003) · Nature reviews. Immunology · doi:10.1038/nri1032 · Cited by 1,319 · see citing works

Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Floess, S., Freyer, J., Siewert, C., Baron, U., Olek, S., Polansky, J. K., Schlawe, K., Chang, H., Bopp, T., Schmitt, E., et al. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050038 · Cited by 1,272 · see citing works

Inducing and expanding regulatory T cell populations by foreign antigen

Kretschmer, K., Apostolou, I., Hawiger, D., Khazaie, K., Nussenzweig, M. C., & von Boehmer, H. (2005) · Nature Immunology · doi:10.1038/ni1265 · Cited by 1,240 · see citing works

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Zheng, Y., Josefowicz, S. Z., Chaudhry, A., Peng, X. P., Forbush, K. A., & Rudensky, A. Y. (2010) · Nature · doi:10.1038/nature08750 · Cited by 1,170 · see citing works

Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

de Lafaille, M. A. C., & Lafaille, J. J. (2009) · Immunity · doi:10.1016/j.immuni.2009.05.002 · Cited by 1,057 · see citing works

Peripheral education of the immune system by colonic commensal microbiota

Lathrop, S. K., Bloom, S. M., Rao, S. M., Nutsch, K., Lio, C.-W., Santacruz, N., Peterson, D. A., Stappenbeck, T. S., & Hsieh, C.-S. (2011) · Nature · doi:10.1038/nature10434 · Cited by 1,034 · see citing works

Regulatory T cells in tumor immunity

Nishikawa, H., & Sakaguchi, S. (2010) · International Journal of Cancer · doi:10.1002/ijc.25429 · Cited by 944 · see citing works

Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.

Hadis, U., Wahl, B., Schulz, O., Hardtke-Wolenski, M., Schippers, A., Wagner, N., Müller, W., Sparwasser, T., Förster, R., & Pabst, O. (2011) · Immunity · doi:10.1016/j.immuni.2011.01.016 · Cited by 893 · see citing works

Extrathymically generated regulatory T cells control mucosal TH2 inflammation

Josefowicz, S. Z., Niec, R. E., Kim, H. Y., Treuting, P. M., Chinen, T., Zheng, Y., Umetsu, D. T., & Rudensky, A. Y. (2012) · Nature · doi:10.1038/nature10772 · Cited by 823 · see citing works

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation

Korn, T., Reddy, J., Gao, W., Bettelli, E., Awasthi, A., Petersen, T. R., Bäckström, B. T., Sobel, R. A., Wucherpfennig, K. W., Strom, T. B., et al. (2007) · Nature Medicine · doi:10.1038/nm1564 · Cited by 803 · see citing works

Transforming Growth Factor-β Controls Development, Homeostasis, and Tolerance of T Cells by Regulatory T Cell-Dependent and -Independent Mechanisms

Li, M. O., Sanjabi, S., & Flavell, R. A. (2006) · Immunity · doi:10.1016/j.immuni.2006.07.011 · Cited by 794 · see citing works

DNA methylation controls Foxp3 gene expression

Polansky, J. K., Kretschmer, K., Freyer, J., Floess, S., Garbe, A. I., Baron, U., Olek, S., Hamann, A., von Boehmer, H., & Huehn, J. (2008) · European Journal of Immunology · doi:10.1002/eji.200838105 · Cited by 784 · see citing works

Stability of the Regulatory T Cell Lineage in Vivo

Rubtsov, Y. P., Niec, R. E., Josefowicz, S., Li, L., Darce, J., Mathis, D., Benoist, C., & Rudensky, A. Y. (2010) · Science · doi:10.1126/science.1191996 · Cited by 730 · see citing works

In Vivo Instruction of Suppressor Commitment in Naive T Cells

Apostolou, I., & von Boehmer, H. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20040249 · Cited by 728 · see citing works

Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.

Hill, J., Feuerer, M., Tash, K., Haxhinasto, S., Perez, J., Melamed, R., Mathis, D., & Benoist, C. (2007) · Immunity · doi:10.1016/j.immuni.2007.09.010 · Cited by 671 · see citing works

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

Miyao, T., Floess, S., Setoguchi, R., Luche, H., Fehling, H. J., Waldmann, H., Huehn, J., & Hori, S. (2012) · Immunity · doi:10.1016/j.immuni.2011.12.012 · Cited by 612 · see citing works

Oral tolerance

Faria, A. M. C., & Weiner, H. L. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00280.x · Cited by 601 · see citing works

Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.Preprint

Deiss, L. P., Feinstein, E., Berissi, H., Cohen, O., & Kimchi, A. (1995) · Genes & Development · doi:10.1101/gad.9.1.15 · Cited by 591 · see citing works

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

Oldenhove, G., Bouladoux, N. J., Wohlfert, E. A., Hall, J. A., Chou, D. B., dos Santos, L. M., O’Brien, S., Blank, R. B., Lamb, E. W., Natarajan, S., et al. (2009) · Immunity · doi:10.1016/j.immuni.2009.10.001 · Cited by 578 · see citing works

Induced CD4⁺Foxp3⁺Regulatory T Cells in Immune Tolerance

Bilate, A. M., & Lafaille, J. J. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-075043 · Cited by 569 · see citing works

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

Lafaille, J. J., Nagashima, K., Katsuki, M., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90419-7 · Cited by 532 · see citing works

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

Huehn, J., Polansky, J. K., & Hamann, A. (2008) · Nature reviews. Immunology · doi:10.1038/nri2474 · Cited by 527 · see citing works

Heterogeneity of natural Foxp3 + T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

Komatsu, N., Mariotti‐Ferrandiz, E., Wang, Y., MALISSEN, B., Waldmann, H., & Hori, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811556106 · Cited by 521 · see citing works

Oral tolerance in the absence of naturally occurring Tregs

Mucida, D. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24487 · Cited by 498 · see citing works

Regulatory T cell development in the absence of functional Foxp3

Lin, W. X., Haribhai, D., Relland, L. M., Truong, N., Carlson, M. R. J., Williams, C. B., & Chatila, T. A. (2007) · Nature Immunology · doi:10.1038/ni1445 · Cited by 485 · see citing works

Frontline: Neuropilin‐1: a surface marker of regulatory T cells

Bruder, D., Probst-Kepper, M., Westendorf, A., Geffers, R., Beissert, S., Loser, K., von Boehmer, H., Buer, J., & Hansen, W. (2004) · European Journal of Immunology · doi:10.1002/eji.200324799 · Cited by 475 · see citing works

Tumor Evasion of the Immune System by Converting CD4+CD25− T Cells into CD4+CD25+ T Regulatory Cells: Role of Tumor-Derived TGF-β

Liu, V. C., Wong, L. Y., Jang, T. L., Shah, A. H., Park, I. I., Yang, X. J., Zhang, Q., Lonning, S. M., Teicher, B. A., & Lee, C. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.5.2883 · Cited by 453 · see citing works

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

Haribhai, D., Williams, J. B., Jia, S., Nickerson, D. W., Schmitt, E. G., Edwards, B., Ziegelbauer, J., Yassai, M. B., Li, S.-H., Relland, L. M., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.03.029 · Cited by 430 · see citing works

Adaptive Foxp3+ Regulatory T Cell-Dependent and -Independent Control of Allergic Inflammation

de Lafaille, M. A. C., Kutchukhidze, N., Shen, S., Ding, Y., Yee, H. T., & Lafaille, J. J. (2008) · Immunity · doi:10.1016/j.immuni.2008.05.010 · Cited by 424 · see citing works

Induction of foxP3 + Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants

Cobbold, S. P., Castejón, R., Adams, E., Zélénika, D., Graça, L., Humm, S., & Waldmann, H. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6003 · Cited by 410 · see citing works

Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition

Sarris, M., Andersen, K., Randow, F., Mayr, L. M., & Betz, A. G. (2008) · Immunity · doi:10.1016/j.immuni.2008.01.012 · Cited by 371 · see citing works

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

de Lafaille, M. A. C., Lino, A. C., Kutchukhidze, N., & Lafaille, J. J. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.12.7259 · Cited by 368 · see citing works

Regulatory CD4+ T Cells Expressing Endogenous T Cell Receptor Chains Protect Myelin Basic Protein–specific Transgenic Mice from Spontaneous Autoimmune Encephalomyelitis

Olivares–Villagómez, D., Wang, Y., & Lafaille, J. J. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.10.1883 · Cited by 294 · see citing works

Tumor-Induced Expansion of Regulatory T Cells by Conversion of CD4+CD25− Lymphocytes Is Thymus and Proliferation Independent

Valzasina, B., Piconese, S., Guiducci, C., & Colombo, M. P. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-4217 · Cited by 258 · see citing works

Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions

Duarte, J. H., Zelenay, S., Bergman, M., Martins, A. C., & Demengeot, J. (2009) · European Journal of Immunology · doi:10.1002/eji.200839196 · Cited by 250 · see citing works

A Central Role for Induced Regulatory T Cells in Tolerance Induction in Experimental Colitis

Haribhai, D., Lin, W. X., Edwards, B., Ziegelbauer, J., Salzman, N. H., Carlson, M. R., Li, S.-H., Simpson, P. M., Chatila, T. A., & Williams, C. B. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802535 · Cited by 226 · see citing works

Natural Regulatory T Cells and De Novo-Induced Regulatory T Cells Contribute Independently to Tumor-Specific Tolerance

Zhou, G., & Levitsky, H. I. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.4.2155 · Cited by 212 · see citing works

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta.

Glinka, Y., Stoilova, S., Mohammed, N., & Prud'homme, G. (2011) · Carcinogenesis · doi:10.1093/carcin/bgq281 · Cited by 186 · see citing works

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

Sharma, M. D., Hou, D., Baban, B., Koni, P. A., He, Y., Chandler, P., Blazar, B. R., Mellor, A. L., & Munn, D. H. (2010) · Immunity · doi:10.1016/j.immuni.2010.11.022 · Cited by 174 · see citing works

Regulatory T cells in spontaneous autoimmune encephalomyelitis

Furtado, G. D. C., Olivares–Villagómez, D., de Lafaille, M. A. C., Wensky, A. K., Latkowski, J.-A. M., & Lafaille, J. J. (2001) · Immunological Reviews · doi:10.1034/j.1600-065x.2001.1820110.x · Cited by 155 · see citing works

Swift Entry of Myelin-Specific T Lymphocytes into the Central Nervous System in Spontaneous Autoimmune Encephalomyelitis

Furtado, G. C., Marcondes, M. C. G., Latkowski, J.-A. M., Tsai, J., Wensky, A. K., & Lafaille, J. J. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.7.4648 · Cited by 136 · see citing works

Prognostic significance of regulatory T cells in tumor

Wilke, C. M., Wu, K., Zhao, E., Wang, G., & Zou, W. (2010) · International Journal of Cancer · doi:10.1002/ijc.25464 · Cited by 119 · see citing works

Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors

Hindley, J. P., Ferreira, C., Jones, E., Lauder, S. N., Ladell, K., Wynn, K. K., Betts, G. J., Singh, Y., Price, D. A., Godkin, A. J., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-1797 · Cited by 118 · see citing works

Hyper Immunoglobulin E Response in Mice with Monoclonal Populations of B and T Lymphocytes✪

de Lafaille, M. A. C., Muriglan, S. J., Sunshine, M. J., Lei, Y., Kutchukhidze, N., Furtado, G. C., Wensky, A. K., Olivares–Villagómez, D., & Lafaille, J. J. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.9.1349 · Cited by 106 · see citing works

Regulatory T cells: stability revisited

Bailey-Bucktrout, S. L., & Bluestone, J. A. (2011) · Trends in Immunology · doi:10.1016/j.it.2011.04.002 · Cited by 104 · see citing works

Regulatory T cells and immune tolerance to tumors

Cao, X. (2009) · Immunologic Research · doi:10.1007/s12026-009-8124-7 · Cited by 75 · see citing works

CD8+ Tumor-Infiltrating Lymphocytes Are Primed for Fas-Mediated Activation-Induced Cell Death But Are Not Apoptotic In Situ

Radoja, S., Saio, M., & Frey, A. B. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.10.6074 · Cited by 59 · see citing works

Neuropilin 1 and CD25 co-regulation during early murine thymic differentiation

Corbel, C., Lemarchandel, V., Thomas‐Vaslin, V., Pelus, A.-S., Agboton, C., & Roméo, P. (2007) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2007.01.009 · Cited by 44 · see citing works

Cutting Edge: Intrathymic Differentiation of Adaptive Foxp3+ Regulatory T Cells upon Peripheral Proinflammatory Immunization

Zelenay, S., Bergman, M., Paiva, R., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001281 · Cited by 20 · see citing works

It Takes Two to Tango

Bilate, A. M. B., & Lafaille, J. J. (2011) · Immunity · doi:10.1016/j.immuni.2011.07.003 · Cited by 15 · see citing works

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature · doi:10.1038/nature12721 · Cited by 5,549 · see citing works

The microbiota in adaptive immune homeostasis and disease

Honda, K., & Littman, D. R. (2016) · Nature · doi:10.1038/nature18848 · Cited by 1,846 · see citing works

The immunology of asthma

Lambrecht, B. N., & Hammad, H. (2015) · Nature Immunology · doi:10.1038/ni.3049 · Cited by 1,673 · see citing works

The microbiota regulates type 2 immunity through RORγt ⁺ T cells

Ohnmacht, C., Park, J.-H., Cording, S., Wing, J. B., Atarashi, K., Obata, Y., Gaboriau-Routhiau, V., Marques, R., Dulauroy, S., Fedoseeva, M., et al. (2015) · Science · doi:10.1126/science.aac4263 · Cited by 863 · see citing works

Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis

Delgoffe, G. M., Woo, S.-R., Turnis, M. E., Gravano, D. M., Guy, C., Overacre, A. E., Bettini, M. L., Vogel, P., Finkelstein, D., Bonnevier, J., et al. (2013) · Nature · doi:10.1038/nature12428 · Cited by 587 · see citing works

Development and maintenance of intestinal regulatory T cells

Tanoue, T., Atarashi, K., & Honda, K. (2016) · Nature Reviews Immunology · doi:10.1038/nri.2016.36 · Cited by 553 · see citing works

Tissue Tregs

Panduro, M., Benoist, C., & Mathis, D. (2016) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095948 · Cited by 536 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology · doi:10.1002/eji.202170126 · Cited by 531 · see citing works

c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont

Xu, M., Pokrovskii, M., Ding, Y., Yi, R., Au, C., Harrison, O. J., Galan, C., Belkaid, Y., Bonneau, R., & Littman, D. R. (2018) · Nature · doi:10.1038/nature25500 · Cited by 498 · see citing works

Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice

Kolodin, D., van Panhuys, N., Li, C., Magnuson, A. M., Cipolletta, D., Miller, C. M., Wagers, A., Germain, R. N., Benoist, C., & Mathis, D. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.03.005 · Cited by 365 · see citing works

Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice

Faith, J. J., Ahern, P. P., Ridaura, V. K., Cheng, J., & Gordon, J. I. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3008051 · Cited by 373 · see citing works

The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation

DuPage, M., Chopra, G., Quiros, J., Rosenthal, W. L., Morar, M. M., Holohan, D., Zhang, R., Turka, L., Marson, A., & Bluestone, J. A. (2015) · Immunity · doi:10.1016/j.immuni.2015.01.007 · Cited by 332 · see citing works

Regulatory T Cell Development

Savage, P. A., Klawon, D. E. J., & Miller, C. H. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-100219-020937 · Cited by 321 · see citing works

Cell surface polysaccharides of <i>Bifidobacterium bifidum</i> induce the generation of Foxp3 ⁺ regulatory T cells

Verma, R., Lee, C., Jeun, E.-J., Yi, J., Kim, K. S., Ghosh, A., Byun, S., Lee, C.-G., Kang, H.-J., Kim, G.-C., et al. (2018) · Science Immunology · doi:10.1126/sciimmunol.aat6975 · Cited by 242 · see citing works

Neuropilin 1: function and therapeutic potential in cancer

Chaudhary, B., Khaled, Y. S., Ammori, B. J., & Elkord, E. (2014) · Cancer Immunology, Immunotherapy · doi:10.1007/s00262-013-1500-0 · Cited by 233 · see citing works

Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation

Klein, L., Robey, E. A., & Hsieh, C.-S. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-018-0083-6 · Cited by 214 · see citing works

mTOR Signaling, Tregs and Immune Modulation

Chapman, N. M., & Chi, H. (2014) · Immunotherapy · doi:10.2217/imt.14.84 · Cited by 148 · see citing works

Neuropilin-1: a checkpoint target with unique implications for cancer immunology and immunotherapy

Chuckran, C. A., Liu, C., Bruno, T. C., Workman, C. J., & Vignali, D. A. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-000967 · Cited by 147 · see citing works

GILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β Signaling

Bereshchenko, O., Coppo, M., Bruscoli, S., Biagioli, M., Cimino, M., Frammartino, T., Sorcini, D., Venanzi, A., Di Sante, M., & Riccardi, C. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.004 · Cited by 131 · see citing works

Regulatory T cells in the face of the intestinal microbiota

Ramanan, D., Pratama, A., Zhu, Y., Venezia, O., Sassone-Corsi, M., Chowdhary, K., Galván-Peña, S., Sefik, E., Brown, C., Gélineau, A., et al. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-023-00890-w · Cited by 126 · see citing works

Mining the human gut microbiota for effector strains that shape the immune system

Ahern, P. P., Faith, J. J., & Gordon, J. I. (2014) · Immunity · doi:10.1016/j.immuni.2014.05.012 · Cited by 123 · see citing works

Helios: still behind the clouds

Thornton, A. M., & Shevach, E. M. (2019) · Immunology · doi:10.1111/imm.13115 · Cited by 101 · see citing works

Treg cell therapy: How cell heterogeneity can make the difference

Giganti, G., Atif, M., Mohseni, Y., Mastronicola, D., Grageda, N., Povoleri, G. A., Miyara, M., & Scottà, C. (2021) · European Journal of Immunology · doi:10.1002/eji.201948131 · Cited by 82 · see citing works

Host-microbiota interactions and adaptive immunity

McCoy, K. D., Ronchi, F., & Geuking, M. B. (2017) · Immunological Reviews · doi:10.1111/imr.12575 · Cited by 77 · see citing works

Reprogrammed CD4+ T Cells That Express FoxP3+ Control Inhibitory Antibody Formation in Hemophilia A Mice

Herzog, R. W., Kuteyeva, V., Saboungi, R., Terhorst, C., & Biswas, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00274 · Cited by 24 · see citing works

Regulatory T Cells: Central Concepts from Ontogeny to Therapy

Khor, B. (2017) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2016.07.003 · Cited by 15 · see citing works

The cytoplasmic domain of neuropilin‐1 regulates focal adhesion turnover

Seerapu, H. R., Borthakur, S., Kong, N., et al. (2013) · FEBS Letters · doi:10.1016/j.febslet.2013.08.040 · Cited by 22 · see citing works

Supplementary Figure 1 from Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis

Benwell, C. J., Johnson, R. T., Taylor, J. A. G. E., et al. (2023) · doi:10.1158/2767-9764.22546182

Supplementary Figure 1 from Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis

Benwell, C. J., Johnson, R. T., Taylor, J. A. G. E., et al. (2023) · doi:10.1158/2767-9764.22546182.v1

Expression and Clinical Significance of Neuropilin-1 in Patients With Multiple Myeloma

Karczmarczyk, A., Bilska, S., Korpysz, M., et al. (2020) · Anticancer Research · doi:10.21873/anticanres.14554 · Cited by 2 · see citing works

Supplementary Figure 3 from Endothelial VEGFR Coreceptors Neuropilin-1 and Neuropilin-2 Are Essential for Tumor Angiogenesis

Benwell, C. J., Johnson, R. T., Taylor, J. A. G. E., et al. (2023) · doi:10.1158/2767-9764.22546176