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The human frontal lobes: Transcending the default mode through contingent encoding.
Abstract
This chapter sets the stage for the rest of the book, presenting anatomical and clinical distinctions that serve as organizational and memory “hooks” for reading many of the other chapters. It discusses how massive damage to the frontal lobes can cause dramatic changes in personality and comportment while keeping sensation, movement, consciousness, and most cognitive faculties. It addresses questions such as: Is there a unitary “frontal lobe syndrome” encompassing all signs and symptoms? Are there regional segregations of function within the frontal lobes? Is it possible to identify a potentially unifying principle of organization which cuts across the heterogeneous specializations attributed to the frontal lobes?
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“I hypothesize, as others do (Mesulam, 2002; Hassabis and Maguire, 2009; Buckner, 2012), that the default mode network is necessary for the brain’s internal model.”
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Metadata
- Authors
- Mesulam, M.-M.
- Affiliations
- Northwestern University (US)
- Corresponding author
- Mesulam, M.-Marsel
- ORCID
- Mesulam, M.-Marsel
- Venue
- Principles of Frontal Lobe Function
- Publisher
- Oxford University Press
- Published
- 2002-08-08
- Pages
- 8-30
- OpenAlex
- W2478443986
- Cited by
- 262
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 7 · 2022: 8 · 2021: 15 · 2020: 7 · 2019: 9 · 2018: 11 · 2017: 14 · 2016: 13 · 2015: 15 · 2014: 7 · 2013: 10 · 2012: 18
- FWCI
- 12.58
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- frontal lobe, frontal lobe syndrome, personality change, regional specialization, default mode network, frontal lobe function
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