Irregular Heavy Drinking Occasions and Risk of Ischemic Heart Disease: A Systematic Review and Meta-Analysis
Abstract
Contrary to a cardioprotective effect of moderate regular alcohol consumption, accumulating evidence points to a detrimental effect of irregular heavy drinking occasions (>60 g of pure alcohol or > or =5 drinks per occasion at least monthly) on ischemic heart disease risk, even for drinkers whose average consumption is moderate. The authors systematically searched electronic databases from 1980 to 2009 for case-control or cohort studies examining the association of irregular heavy drinking occasions with ischemic heart disease risk. Studies were included if they reported either a relative risk estimate for intoxication or frequency of > or =5 drinks stratified by or adjusted for total average alcohol consumption. The search identified 14 studies (including 31 risk estimates) containing 4,718 ischemic heart disease events (morbidity and mortality). Using a standardized protocol, the authors extracted relative risk estimates and their variance, in addition to study characteristics. In a random-effects model, the pooled relative risk of irregular heavy drinking occasions compared with regular moderate drinking was 1.45 (95% confidence interval: 1.24, 1.70), with significant between-study heterogeneity (I(2) = 53.9%). Results were robust in several sensitivity analyses. The authors concluded that the cardioprotective effect of moderate alcohol consumption disappears when, on average, light to moderate drinking is mixed with irregular heavy drinking occasions.
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There is evidence for an increased risk associated with irregular heavy drinking, even in people who are on average light to moderate drinkers, for ischaemic heart disease, ischaemic stroke, all types of stroke, and different cardiovascular outcomes.
“but there is also evidence for an increased risk associated with irregular heavy drinking, even in people who are on average light to moderate drinkers (ischaemic heart disease 247, 248, 249; ischaemic stroke 250; all types of stroke 251; different cardiovascular outcomes 252).”
From The relationship between different dimensions of alcohol use and the burden of disease—an update (2017) · cites this paper as [247]
In a meta-analysis, irregular binge drinking (>60 g pure alcohol or ≥5 drinks per occasion at least monthly) increased CHD risk by 45% (RR 1.45, 95% CI 1.24-1.70).
“Patterns of alcohol consumption may be a particularly important determinant of the magnitude of the association—in a meta-analysis of 10 prospective cohort and 4 case-control studies, irregular “binge” drinking (>60 g of pure alcohol or >=5 drinks per occasion at least monthly) increased CHD risk by 45% (RR: 1.45; 95% CI: 1.24 to 1.70) (276).”
From Food Consumption and its Impact on Cardiovascular Disease: Importance of Solutions Focused on the Globalized Food System (2015) · cites this paper as [276]
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Cites
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · see citing works
Quantifying heterogeneity in a meta‐analysis
Higgins, J. P. T., & Thompson, S. G. (2002) · Statistics in Medicine · doi:10.1002/sim.1186 · Cited by 36,763 · see citing works
Projections of Global Mortality and Burden of Disease from 2002 to 2030
Mathers, C. D., & Loncar, D. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030442 · Cited by 11,386 · see citing works
Lopez, A. D., Mathers, C. D., Ezzati, M., Jamison, D. T., & Murray, C. J. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68770-9 · Cited by 5,630 · see citing works
The combination of estimates from different experiments
Cochran, W. G. (1954) · Biometrics · doi:10.2307/3001666 · Cited by 5,380 · see citing works
Ezzati, M., López, A. D., Rodgers, A., & Murray, C. J. L. (2004) · Cited by 3,319 · see citing works
Cardiovascular Survey Methods.
Rose, G., & Blackburn, H. (1968) · Annals of Internal Medicine · doi:10.7326/0003-4819-69-6-1335_2 · Cited by 3,065 · see citing works
How should meta‐regression analyses be undertaken and interpreted?
Thompson, S. G., & Higgins, J. P. T. (2002) · Statistics in Medicine · doi:10.1002/sim.1187 · Cited by 3,026 · see citing works
Comparison of two methods to detect publication bias in meta-analysis.
Peters, J. L. (2006) · JAMA · doi:10.1001/jama.295.6.676 · Cited by 2,278 · see citing works
A modified test for small‐study effects in meta‐analyses of controlled trials with binary endpoints
Harbord, R. M., Egger, M., & Sterne, J. A. C. (2006) · Statistics in Medicine · doi:10.1002/sim.2380 · Cited by 2,267 · see citing works
Tunstall-Pedoe, H., Kuulasmaa, K., Amouyel, P., Arveiler, D., Rajakangas, A.-M., & Pająk, A. (1994) · Circulation · doi:10.1161/01.cir.90.1.583 · Cited by 2,260 · see citing works
(1999) · PubMed · Cited by 2,062 · see citing works
The case of the misleading funnel plot
Lau, J., Ioannidis, J. P. A., Terrin, N., Schmid, C. H., & Olkin, I. (2006) · BMJ · doi:10.1136/bmj.333.7568.597 · Cited by 1,766 · see citing works
Sudden Cardiac Death in the United States, 1989 to 1998
Zheng, Z.-J., Croft, J., Giles, W., & Mensah, G. (2001) · Circulation · doi:10.1161/hc4301.098254 · Cited by 1,611 · see citing works
Rimm, E. B., Williams, P., Fosher, K., Criqui, M., & Stampfer, M. J. (1999) · BMJ · doi:10.1136/bmj.319.7224.1523 · Cited by 1,360 · see citing works
Statistics Notes: The odds ratio
Bland, J. M. (2000) · BMJ · doi:10.1136/bmj.320.7247.1468 · Cited by 1,298 · see citing works
A meta-analysis of alcohol consumption and the risk of 15 diseases
Corrao, G. (2004) · Preventive Medicine · doi:10.1016/j.ypmed.2003.11.027 · Cited by 1,077 · see citing works
Metan: fixed- and random-effects meta-analysis
Harris, R. J., Deeks, J. J., Altman, D. G., Bradburn, M. J., Harbord, R. M., & Sterne, J. A. C. (2008) · The Stata Journal: Promoting communications on statistics and Stata · doi:10.1177/1536867x0800800102 · Cited by 1,027 · see citing works
Rehm, J., Room, R., Graham, K., Monteiro, M., Gmel, G., & Sempos, C. T. (2003) · Addiction · doi:10.1046/j.1360-0443.2003.00467.x · Cited by 995 · see citing works
Self-citationRimm, E. B., Klatsky, A., Grobbee, D., & Stampfer, M. J. (1996) · BMJ · doi:10.1136/bmj.312.7033.731 · Cited by 992 · see citing works
Binge Drinking Among US Adults
Naimi, T. S., Brewer, R. D., Mokdad, A., Denny, C., Serdula, M. K., & Marks, J. S. (2003) · JAMA · doi:10.1001/jama.289.1.70 · Cited by 987 · see citing works
Clarke, R., Shipley, M. J., Lewington, S., Youngman, L. D., Collins, R., Marmot, M. G., & Peto, R. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a010013 · Cited by 879 · see citing works
Alcohol and coronary heart disease: a meta-analysis.
Corrao, G., Rubbiati, L., Bagnardi, V., Zambon, A., & Poikolainen, K. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.951015056.x · Cited by 875 · see citing works
Roles of Drinking Pattern and Type of Alcohol Consumed in Coronary Heart Disease in Men
Mukamal, K. J., Conigrave, K. M., Mittleman, M. A., Camargo, C. A., Stampfer, M. J., Willett, W. C., & Rimm, E. B. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022095 · Cited by 805 · see citing works
ALCOHOL AND MORTALITY IN BRITISH MEN: EXPLAINING THE U-SHAPED CURVE
Shaper, A. G., Wannamethee, G., & Walker, M. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92890-5 · Cited by 780 · see citing works
Meta-Analysis of Wine and Beer Consumption in Relation to Vascular Risk
Castelnuovo, A. F. D., Rotondo, S., Iacoviello, L., Donati, M. B., & de Gaetano, G. (2002) · Circulation · doi:10.1161/01.cir.0000018653.19696.01 · Cited by 562 · see citing works
Evans, D. J., Sharp, W. R., & Ammirato, P. V. (1986) · Macmillan , Collier-Macmillan eBooks · Cited by 547 · see citing works
Does diet or alcohol explain the French paradox?
Criqui, M. H. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92883-5 · Cited by 520 · see citing works
Stockwell, T. R., Donath, S. M., Cooper‐Stanbury, M., Chikritzhs, T. N., Catalano, P., & Mateo, C. (2004) · Addiction · doi:10.1111/j.1360-0443.2004.00815.x · Cited by 488 · see citing works
The quanitification of drug caused morbidity and mortality in Australia: Part 1
English, D. R., Holman, D., Milne, E., Winter, M., Hulse, G. K., Codde, J., Bower, C., Giles‐Corti, B., Dawes, V. P., de Klerk, N. H., et al. (1995) · UWA Profiles and Research Repository (UWA) · Cited by 464 · see citing works
Fillmore, K. M., Stockwell, T., Chikritzhs, T., Bostrom, A., & Kerr, W. (2007) · Annals of Epidemiology · doi:10.1016/j.annepidem.2007.01.005 · Cited by 402 · see citing works
Taylor, B., Irving, H. M., Baliunas, D., Roerecke, M., Patra, J., Mohapatra, S., & Rehm, J. (2009) · Addiction · doi:10.1111/j.1360-0443.2009.02694.x · Cited by 346 · see citing works
Self-citationCROSS-CULTURAL AND ANTHROPOBIOLOGICAL REFLECTIONS ON AFRICAN UVULECTOMY
Wind, J. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92809-5 · Cited by 317 · see citing works
Influence of pattern of drinking on cardiovascular disease and cardiovascular risk factors–a review.
Puddey, I. B., Rakic, V., Dimmitt, S. B., & Beilin, L. J. (1999) · Addiction · doi:10.1046/j.1360-0443.1999.9456493.x · Cited by 309 · see citing works
Alcohol and mortality: a review of prospective studies
Shaper, A. G. (1990) · British Journal of Addiction · doi:10.1111/j.1360-0443.1990.tb03710.x · Cited by 299 · see citing works
Kauhanen, J., Kaplan, G. A., Goldberg, D. E., & Salonen, J. T. (1997) · BMJ · doi:10.1136/bmj.315.7112.846 · Cited by 278 · see citing works
McElduff, P., & Dobson, A. J. (1997) · BMJ · doi:10.1136/bmj.314.7088.1159 · Cited by 270 · see citing works
Murray, R. P., Connett, J. E., Tyas, S. L., Bond, R., Ekuma, O., Silversides, C. K., & Barnes, G. E. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.3.242 · Cited by 266 · see citing works
Mckee, M., & Britton, A. (1998) · Journal of the Royal Society of Medicine · doi:10.1177/014107689809100802 · Cited by 264 · see citing works
Lemmens, P. H. H. M., Tan, E. S., & Knibbe, R. A. (1992) · Journal of Studies on Alcohol · doi:10.15288/jsa.1992.53.476 · Cited by 252 · see citing works
Malyutina, S. K., Bobák, M., Kurilovitch, S., Гафаров, В. В., Симонова, Г. И., IuP, N., & Marmot, M. G. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11470-x · Cited by 242 · see citing works
Britton, A., & McKee, M. (2000) · Journal of Epidemiology and Community Health · doi:10.1136/jech.54.5.328 · Cited by 239 · see citing works
Alcohol and sudden cardiac death
Wannamethee, S. G., & Shaper, A. G. (1992) · Heart · doi:10.1136/hrt.68.11.443 · Cited by 227 · see citing works
Pearson, T. A. (1996) · Circulation · doi:10.1161/01.cir.94.11.3023 · Cited by 223 · see citing works
Risk Factors for Sudden Cardiac Death in Middle-Aged British Men
Wannamethee, S. G., Shaper, A. G., Macfarlane, P. W., & Walker, M. (1995) · Circulation · doi:10.1161/01.cir.91.6.1749 · Cited by 210 · see citing works
Moderate Alcohol Consumption and the Risk of Sudden Cardiac Death Among US Male Physicians
Albert, C. M., Manson, J. E., Cook, N. R., Ajani, U. A., Gaziano, J. M., & Hennekens, C. H. (1999) · Circulation · doi:10.1161/01.cir.100.9.944 · Cited by 206 · see citing works
Alcohol and cardiovascular mortality in Moscow; new evidence of a causal association.
Chenet, L., McKee, M., Leon, D. A., Школьников, В. М., & Vassin, S. (1998) · Journal of Epidemiology & Community Health · doi:10.1136/jech.52.12.772 · Cited by 202 · see citing works
The "Holiday Heart": Electrophysiologic Studies of Alcohol Effects in Alcoholics
Greenspon, A. J., & SCHAAL, S. F. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-98-2-135 · Cited by 181 · see citing works
Prospective study of alcohol drinking patterns and coronary heart disease in women and men
Tolstrup, J. S., Jensen, M. K., Tjønneland, A. M., Overvad, K., Mukamal, K. J., & Grønbæk, M. (2006) · BMJ · doi:10.1136/bmj.38831.503113.7c · Cited by 179 · see citing works
Drinking habits and cardiovascular disease: The Framingham Study
Gordon, T., & Kannel, W. B. (1983) · American Heart Journal · doi:10.1016/0002-8703(83)90492-1 · Cited by 174 · see citing works
(2003) · PubMed · doi:10.1097/01.hjr.0000051961.68260.30 · Cited by 166 · see citing works
Self-citationBagnardi, V, Zatonski, W., Scotti, L., La Vecchia, C., & Corrao, G. (2008) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2007.065607 · Cited by 165 · see citing works
Rehm, J., Sempos, C. T., & Trevisan, M. (2003) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/174182670301000104 · Cited by 164 · see citing works
Self-citationBinge-Trinken in Europa: Definitionen, Epidemiologie und Folgen
Gmel, G. E., Rehm, J. T., & Kuntsche, E. N. (2003) · SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice · doi:10.1024/suc.2003.49.2.105 · Cited by 157 · see citing works
Self-citationGmel, G. E., Gutjahr, E., & Rehm, J. T. (2003) · European Journal of Epidemiology · doi:10.1023/a:1024805021504 · Cited by 153 · see citing works
Self-citationIncreased mortality related to heavy alcohol intake pattern
Laatikainen, T. K., Manninen, L., Poikolainen, K., & Vartiainen, E. (2003) · Journal of Epidemiology & Community Health · doi:10.1136/jech.57.5.379 · Cited by 116 · see citing works
Trends in alcohol use and binge drinking, 1985–1999
Serdula, M. K., Brewer, R. D., Gillespie, C., Denny, C. H., & Mokdad, A. H. (2004) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2003.12.017 · Cited by 108 · see citing works
[Alcohol consumption and mortality].
Allebeck, P. (2002) · PubMed · Cited by 108 · see citing works
Overview of studies on drinking patterns and consequences
Bondy, S. J. (1996) · Addiction · doi:10.1046/j.1360-0443.1996.911116637.x · Cited by 101 · see citing works
Fuchs, F. D. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh229 · Cited by 99 · see citing works
Alcohol and coronary heart disease*
Marmot, M. G. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.4.724 · Cited by 91 · see citing works
Alcohol Consumption and Sudden Coronary Death in Middle‐aged Finnish Men
SUHONEN, O., Aromaa, A., Reunanen, A., & Knekt, P. (1987) · Acta Medica Scandinavica · doi:10.1111/j.0954-6820.1987.tb03353.x · Cited by 86 · see citing works
Daily variations in deaths in Lithuania: the possible contribution of binge drinking
Chenet, L., Britton, A. R., Kalèdiené, R., & Petrauskienė, J. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.4.743 · Cited by 85 · see citing works
Evans, C. (2000) · BMJ · doi:10.1136/bmj.320.7229.218 · Cited by 78 · see citing works
Provocation of Ventricular Tachycardia after Consumption of Alcohol
Greenspon, A. J., Stang, J. M., Lewis, R. P., & Schaal, S. F. (1979) · New England Journal of Medicine · doi:10.1056/nejm197911083011906 · Cited by 77 · see citing works
Alcohol and coronary heart disease
(1996) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(96)80386-3 · Cited by 77 · see citing works
Школьников, В. М., McKee, M., Chervyakov, V. V., & Kyrianov, N. A. (2002) · Journal of Epidemiology & Community Health · doi:10.1136/jech.56.3.171 · Cited by 76 · see citing works
DRINKING HABITS AND CORONARY HEART DISEASE
Kozarević, D., Demirovic, J., Gordon, T., Kaelber, C. T., McGee, D., & Zukel, W. J. (1982) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113464 · Cited by 73 · see citing works
Drinking pattern and risk of non‐fatal myocardial infarction: a population‐based case–control study
Trevisan, M., Dorn, J. M., Falkner, K. L., Russell, M., Ram, M., Muti, P. C., Freudenheim, J. L., Nochajaski, T., & Hovey, K. M. (2004) · Addiction · doi:10.1111/j.1360-0443.2003.00630.x · Cited by 71 · see citing works
Alcohol, Type of Alcohol, and All‐Cause and Coronary Heart Disease Mortality
Grønbæk, M. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02902.x · Cited by 67 · see citing works
Alcohol and ischaemic heart disease in middle aged British men.
Shaper, A. G., Phillips, A. N., Pocock, S., & Walker, M. (1987) · BMJ · doi:10.1136/bmj.294.6574.733 · Cited by 66 · see citing works
Guiraud, A., de Lorgeril, M., Boucher, F. R., Berthonneche, C., Rakotovao, A., & de Leiris, J. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.02.003 · Cited by 58 · see citing works
EDITORIAL Alcohol consumption and mortality. What do we know and where should we go?
Rehm, J. (2000) · Addiction · doi:10.1046/j.1360-0443.2000.9579891.x · Cited by 56 · see citing works
Self-citationAlcohol intake, drinking patterns, and risk of nonfatal acute myocardial infarction in Costa Rica
Kabagambe, E. K., Baylín, A., Ruiz-Narváez, E., Rimm, E. B., & Campos, H. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.6.1336 · Cited by 54 · see citing works
Harriss, L. R., English, D. R., Hopper, J. L., Powles, J. W., Simpson, J. A., O’Dea, K., Giles, G. G., & Tonkin, A. M. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01947.x · Cited by 50 · see citing works
Comparability of Old and New World Health Organization Criteria for Definite Myocardial Infarction
Beaglehole, R., Stewart, A. W., & BUzTLER, M. (1987) · International Journal of Epidemiology · doi:10.1093/ije/16.3.373 · Cited by 48 · see citing works
Overview of studies on drinking patterns and consequences
Bondy, S. J. (1996) · Addiction · doi:10.1111/j.1360-0443.1996.tb02269.x · Cited by 48 · see citing works
Alcohol and cardiovascular disease - more than one paradox to consider
Beilin, L. J., & Puddey, I. B. (2003) · Journal of Cardiovascular Risk · doi:10.1097/00043798-200302000-00001 · Cited by 43 · see citing works
Mäkelä, P., Paljärvi, T., & Poikolainen, K. (2005) · Journal of Studies on Alcohol · doi:10.15288/jsa.2005.66.722 · Cited by 42 · see citing works
Patterns of alcohol consumption in middle-aged men from France and Northern Ireland. The PRIME Study
Marques-Vidal, P. M., Arveiler, D., Evans, A., Montaye, M., Bingham, A., Ruidavets, J., McMaster, D., Haas, B., Amouyel, P., & Ducimetière, P. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600954 · Cited by 41 · see citing works
Poikolainen, K. (1983) · International Journal of Epidemiology · doi:10.1093/ije/12.2.151 · Cited by 41 · see citing works
It can be bad for the heart, too‐drinking patterns and coronary heart disease
Poikolainen, K. (1998) · Addiction · doi:10.1046/j.1360-0443.1998.931217571.x · Cited by 38 · see citing works
Marques-Vidal, P. M., Montaye, M., Arveiler, D., Evans, A., Bingham, A., Ruidavets, J., Amouyel, P., Haas, B., Yarnell, J., Ducimetière, P., et al. (2004) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/01.hjr.0000136416.24769.42 · Cited by 35 · see citing works
Hammar, N., Romelsjö, A., & Alfredsson, L. S. (1997) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1997.92106000.x · Cited by 33 · see citing works
Bastian, A. J. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb07552.x · Cited by 30 · see citing works
Weekend binge drinking may be linked to Monday peaks in cardiovascular deaths
Chenet, L., & Britton, A. R. (2001) · BMJ · doi:10.1136/bmj.322.7292.998 · Cited by 29 · see citing works
Alcohol drinking pattern and non‐fatal myocardial infarction in women
Dorn, J. M., Hovey, K. M. O., Williams, B. A., Freudenheim, J. L., Russell, M., Nochajski, T. H., & Trevisan, M. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01765.x · Cited by 28 · see citing works
Grønbæk, M. (2003) · Pathophysiology · doi:10.1016/j.pathophys.2003.10.004 · Cited by 28 · see citing works
Alcohol consumption and mortality—questions about causality, confounding and methodology
Rehm, J. T., & Sempos, C. T. (1995) · Addiction · doi:10.1111/j.1360-0443.1995.tb02184.x · Cited by 27 · see citing works
Self-citationMetcalfe, J. (1993) · Physics World · doi:10.1088/2058-7058/6/10/32 · Cited by 25 · see citing works
Patterns of Alcohol Consumption and Acute Myocardial Infarction: A Case-Crossover Analysis
Gerlich, M. G., Krämer, A., Gmel, G. E., Maggiorini, M., Lüscher, T. F., Rickli, H., Kleger, G., & Rehm, J. T. (2009) · European Addiction Research · doi:10.1159/000213641 · Cited by 23 · see citing works
Self-citationCase fatality after an acute cardiac event
McElduff, P., & Dobson, A. J. (2001) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00265-1 · Cited by 18 · see citing works
Peasey, A., Bobák, M., Malyutina, S. K., Pająk, A., Kubínová, R., Pikhart, H., Kurilovitch, S., Poledne, R., & Marmot, M. G. (2005) · Alcohol and Alcoholism · doi:10.1093/alcalc/agh161 · Cited by 17 · see citing works
Sempos, C. T., Rehm, J. T., Crespo, C. J., & Trevisan, M. (2002) · Contemporary Drug Problems · doi:10.1177/009145090202900407 · Cited by 10 · see citing works
Self-citationThe Importance of Keeping Regular: Accurate Guidance to the Public on Low-Risk Drinking Levels
Heather, N. (2009) · Alcohol and Alcoholism · doi:10.1093/alcalc/agp021 · Cited by 9 · see citing works
ALCOHOL AND ISCHEMIC-HEART-DISEASE IN MIDDLE-AGED BRITISH MEN - REPLY
Shaper, A. G., Phillips, A. N., Pocock, S., & Walker, M. (1987) · Cited by 8 · see citing works
Review: Alcohol and heart disease
Britton, A. R. (2004) · European Journal of Public Health · doi:10.1093/eurpub/14.2.217-b · Cited by 2 · see citing works
Flagged first, then by citations
1 of the 99 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Gmel G, Rehm J, Kuntsche E. Binge drinking in Europe: definitions, epidemiology, and consequences. Sucht. 2003; 49(2):105-116.
- Britton A, McKee M. The relation between alcohol and car- diovascular disease in Eastern Europe: explaining the paradox. J Epidemiol Community Health. 2000;54(5):328-332.
- Greenland S, Rothman KJ. Introduction to categorical statis- tics. In: Rothman KJ, Greenland S, Lash TL, eds. Modern Epidemiology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008:238-257.
Cited by
Sorted by citations
Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., AlMazroa, M. A., Amann, M., Anderson, H. R., Andrews, K. G., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)61766-8 · Cited by 11,805 · see citing works
Grant, B. F., Chou, S. P., Saha, T. D., Pickering, R. P., Kerridge, B. T., Ruan, W. J., Huang, B., Jung, J., Zhang, H., Fan, A., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.2161 · Cited by 1,362 · see citing works
The relationship between different dimensions of alcohol use and the burden of disease—an update
Rehm, J., Gmel, G. E., Gmel, G., Hasan, O. S. M., Imtiaz, S., Popova, S., Probst, C., Roerecke, M., Room, R., Samokhvalov, A. V., et al. (2017) · Addiction · doi:10.1111/add.13757 · Cited by 1,204 · see citing works
Self-citationThe relation between different dimensions of alcohol consumption and burden of disease: an overview
Rehm, J., Baliunas, D., Borges, G. L. G., Graham, K., Irving, H., Kehoe, T., Parry, C. D., Patra, J., Popova, S., Poznyak, V., et al. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.02899.x · Cited by 1,174 · see citing works
Self-citationBehavioral and Dietary Risk Factors for Noncommunicable Diseases
Ezzati, M., & Ríboli, E. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1203528 · Cited by 744 · see citing works
Stockwell, T. R., Zhao, J., Panwar, S., Roemer, A., Naimi, T. S., & Chikritzhs, T. N. (2016) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2016.77.185 · Cited by 658 · see citing works
“It has been demonstrated that a pattern of heavy episodic (i.e., “binge”) drinking is not associated with the appearance of reduced health risks even when average daily volume is low (Roerecke & Rehm, 2010).”
BackgroundAnand, S. S., Hawkes, C., de Souza, R. J., Mente, A., Dehghan, M., Nugent, R., Zulyniak, M. A., Weis, T., Bernstein, A. M., Krauss, R. M., et al. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.07.050 · Cited by 507 · see citing works
Chronic diseases and conditions related to alcohol use
Shield, K. (2013) · Alcohol Research: Current Reviews · doi:10.35946/arcr.v35.2.06 · Cited by 488 · see citing works
Kontis, V., Mathers, C. D., Rehm, J., Stevens, G. A., Shield, K. D., Bonita, R., Riley, L. M., Poznyak, V., Beaglehole, R., & Ezzati, M. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60616-4 · Cited by 418 · see citing works
Self-citationMultiple health behaviours: overview and implications
Spring, B., Moller, A. C., & Coons, M. J. (2012) · Journal of Public Health · doi:10.1093/pubmed/fdr111 · Cited by 408 · see citing works
The 2015 Dutch food-based dietary guidelines
Kromhout, D., Spaaij, C. J. K., de Goede, J., & Weggemans, R. M. (2016) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2016.52 · Cited by 400 · see citing works
Binge drinking: Health impact, prevalence, correlates and interventions
Kuntsche, E. N., Kuntsche, S., Thrul, J., & Gmel, G. E. (2017) · Psychology and Health · doi:10.1080/08870446.2017.1325889 · Cited by 407 · see citing works
“Roerecke and Rehm (2010) showed that beneficial effects of moderate alcohol use on ischaemic heart disease did not persist among usually moderate drinkers if they also had infrequent binge drinking occasions.”
BackgroundKnott, C., Bell, S., & Britton, A. (2015) · Diabetes Care · doi:10.2337/dc15-0710 · Cited by 375 · see citing works
“This analysis mirrored findings from earlier studies (43,44) and suggests that a higher degree of heavy episodic drinking among men may go some way toward explaining observed sex-specific differences in the”
ResultRoerecke, M., & Rehm, J. (2014) · BMC Medicine · doi:10.1186/s12916-014-0182-6 · Cited by 342 · see citing works
“Second, we searched for original articles, excluding letters, editorials, conference abstracts, reviews, and comments, for variations of search terms for the exposure (alcohol consumption), outcome (IHD), and study design based on previous meta-analyses [15,26].”
BackgroundMethodResultInfluentialSelf-citationContributions of risk factors and medical care to cardiovascular mortality trends
Ezzati, M., Obermeyer, Z., Tzoulaki, I., Mayosi, B. M., Elliott, P., & Leon, D. A. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.82 · Cited by 336 · see citing works
Alcohol consumption and non‐communicable diseases: epidemiology and policy implications
Parry, C. D. H., Patra, J., & Rehm, J. T. (2011) · Addiction · doi:10.1111/j.1360-0443.2011.03605.x · Cited by 310 · see citing works
“For on average light to moderate drinking there is a protective effect on ischaemic diseases, which disappears when this drinking style contains irregular heavy drinking occasions [25;26].”
Self-citationOkamura, T., Tsukamoto, K., Arai, H., Fujioka, Y., Ishigaki, Y., Koba, S., Ohmura, H., Shoji, T., Yokote, K., Yoshida, H., et al. (2023) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2022 · Cited by 317 · see citing works
Effects of moderate beer consumption on health and disease: A consensus document
de Gaetano, G., Costanzo, S., Castelnuovo, A. F. D., Badimón, L., Bejko, D., Alkerwi, A., Chiva‐Blanch, G., Estruch, R., Vecchia, C. L., Panico, S., et al. (2016) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2016.03.007 · Cited by 283 · see citing works
“While alcohol misuse can 9 present health risks in all age groups, it is even more dangerous for children and adolescents.(99,100) 10 National surveys-based data: adolescents and young adults (16-24 years) The European School 11 Survey Project on Alcohol and Other Drugs (ESPAD-2011), conducted among 100,000 students i…”
Association Between Daily Alcohol Intake and Risk of All-Cause Mortality
Zhao, J., Stockwell, T. R., Naimi, T. S., Churchill, S., Clay, J. M., & Sherk, A. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2023.6185 · Cited by 265 · see citing works
Roerecke, M., & Rehm, J. (2012) · Addiction · doi:10.1111/j.1360-0443.2012.03780.x · Cited by 249 · see citing works
“However, at the same time it seems that this does not apply to all drinkers and that other determinants of the alcohol effect on heart disease that were not captured by average consumption as an exposure measurement, such as drinking patterns (29), might play an important role.”
BackgroundSelf-citationNeufeld, M., & Rehm, J. T. (2013) · Alcohol and Alcoholism · doi:10.1093/alcalc/ags134 · Cited by 246 · see citing works
“…related to alcohol in Russia for a number of reasons: first, the drinking pattern in Russia is clearly not cardioprotective (Puddey et al., 1999; Roerecke and Rehm, 2010); secondly, many of the CVDs that are detrimentally impacted by alcohol are prevalent in Russia such as haemorrhagic stroke…”
BackgroundSelf-citationBellis, M. A., Hughes, K. E., Nicholls, J. Q., Sheron, N., Gilmore, I. T., & Jones, L. (2016) · BMC Public Health · doi:10.1186/s12889-016-2766-x · Cited by 241 · see citing works
“Thus, even occasional heavy drinking sessions (>60 g pure alcohol at least monthly) remove any benefits from reduced risks of ischaemic heart disease (IHD) that individuals might otherwise accrue from moderate drinking [14].”
BackgroundWorldwide Exposures to Cardiovascular Risk Factors and Associated Health Effects
Tzoulaki, I., Elliott, P., Kontis, V., & Ezzati, M. (2016) · Circulation · doi:10.1161/circulationaha.115.008718 · Cited by 236 · see citing works
Can Noncommunicable Diseases Be Prevented? Lessons from Studies of Populations and Individuals
Ezzati, M., & Ríboli, E. (2012) · Science · doi:10.1126/science.1227001 · Cited by 224 · see citing works
Alcohol consumption as a cause of cancer
CONNOR, J. L. (2016) · Addiction · doi:10.1111/add.13477 · Cited by 228 · see citing works
“The mechanisms suggested for cardioprotection are sensitive to regularity of drinking, and epidemiological studies across populations show that the benefits are not observed in groups with heavy drinking occasions, even if average consumption is moderate [37].”
BackgroundCoronary heart disease prevention: Nutrients, foods, and dietary patterns
Bhupathiraju, S. N., & Tucker, K. L. (2011) · Clinica Chimica Acta · doi:10.1016/j.cca.2011.04.038 · Cited by 224 · see citing works
Alcohol and Human Health: What Is the Evidence?
Hendriks, H. (2020) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-032519-051827 · Cited by 217 · see citing works
Cardiovascular Disease and Homelessness
Baggett, T. P., Liauw, S. S. L., & Hwang, S. W. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.02.077 · Cited by 203 · see citing works
Alcoholic Cardiomyopathy: Pathophysiologic Insights
Piano, M. R., & Phillips, S. A. (2014) · Cardiovascular Toxicology · doi:10.1007/s12012-014-9252-4 · Cited by 200 · see citing works
Physical, Psychological and Chemical Triggers of Acute Cardiovascular Events
Mittleman, M. A., & Mostofsky, E. (2011) · Circulation · doi:10.1161/circulationaha.110.968776 · Cited by 199 · see citing works
Naimi, T. S., Stockwell, T. R., Zhao, J., Xuan, Z., Dangardt, F., Saitz, R., Liang, W., & Chikritzhs, T. N. (2016) · Addiction · doi:10.1111/add.13451 · Cited by 197 · see citing works
“This is relevant in that binge drinking appears to nullify any apparent protective effects on coronary heart disease (CHD), even among thosewith relatively low levels of average consumption [8].”
BackgroundChiva‐Blanch, G., & Badimón, L. (2019) · Nutrients · doi:10.3390/nu12010108 · Cited by 188 · see citing works
“In fact, heavy and irregular binge drinking (>60 g alcohol) is associated to increased arterial stiffness [22], even at early ages [23], and with a 45% increased risk of ischemic heart disease compared to moderate drinking [24].”
BackgroundRisky single‐occasion drinking: bingeing is not bingeing
Gmel, G. E., Kuntsche, E. N., & Rehm, J. T. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.03167.x · Cited by 185 · see citing works
Self-citationHarm reduction -a systematic review on effects of alcohol reduction on physical and mental symptoms
Charlet, K., & Heinz, A. (2016) · Addiction Biology · doi:10.1111/adb.12414 · Cited by 184 · see citing works
“Further information on inclusion of alcohol-dependent patients, or whether it was tested for alcohol use disorder, respectively, was missed in four studies (Hsieh et al. 1995; Xin et al. 2001; Roerecke & Rehm 2010; Ronksley et al. 2011).”
BackgroundMethodInfluentialAlcohol use disorders and the heart
Day, E., & Rudd, J. H. F. (2019) · Addiction · doi:10.1111/add.14703 · Cited by 183 · see citing works
“< five×/week) had a 45% increased morbidity and mortality risk from ischaemic heart disease compared with individuals with a regular, moderate alcohol use pattern, even after adjusting for study type, subject age and smoking, and exclusion of former drinkers to control for sick quitters [16].”
BackgroundA narrative review of alcohol consumption as a risk factor for global burden of disease
Rehm, J., & Imtiaz, S. (2016) · Substance Abuse Treatment, Prevention, and Policy · doi:10.1186/s13011-016-0081-2 · Cited by 177 · see citing works
“The field of cardiovascular outcomes has been less stable, in part, because two dimensions of alcohol consumption need to be taken into consideration, average volume and patterns of drinking, in particular heavy drinking occasions (in general: [88]; for cardiovascular in particular see [16, 89]), and because there are…”
BackgroundSelf-citationBresin, K., & Mekawi, Y. (2020) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14518 · Cited by 178 · see citing works
Kehoe, T., Gmel, G., Shield, K. D., Gmel, G., & Rehm, J. (2012) · Population Health Metrics · doi:10.1186/1478-7954-10-6 · Cited by 160 · see citing works
“For most major diseases where alcohol plays a role (for example, alcohol-attributable cancers, pancreatitis, and cirrhosis of the liver), the average volume of alcohol consumption alone was found to be an adequate predictor of the risk [3,8-10]; however, some diseases and injuries (for example, ischemic heart disease,…”
BackgroundSelf-citationAlcohol’s Impact on the Cardiovascular System
Roerecke, M. (2021) · Nutrients · doi:10.3390/nu13103419 · Cited by 170 · see citing works
Self-citationBakaloudi, D. R., Jeyakumar, D. T., Jayawardena, R., & Chourdakis, M. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.04.020 · Cited by 167 · see citing works
“Nevertheless, subjects who often consume alcohol are not only more prone to viral and bacterial infections (including COVID-19) due to their impaired immune system [58,59], to CVD in heavy drinking occasions [60], liver [61],”
Epidemiology and alcohol policy in Europe
Rehm, J. T., Zatonksi, W., Taylor, B., & Anderson, P. (2011) · Addiction · doi:10.1111/j.1360-0443.2010.03326.x · Cited by 147 · see citing works
Self-citationRehm, J. T. (2013) · Alcohol research · doi:10.35946/arcr.v35.2.07 · Cited by 145 · see citing works
Self-citationRosoff, D. B., Clarke, T., Adams, M. J., McIntosh, A. M., Smith, G. D., Jung, J., & Lohoff, F. W. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0535-9 · Cited by 126 · see citing works
Alcohol Consumption, Heavy Drinking, and Mortality: Rethinking the J-Shaped Curve
Plunk, A. D., Syed‐Mohammed, H., Cavazos‐Rehg, P. A., Bierut, L. J., & Grucza, R. A. (2013) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12250 · Cited by 127 · see citing works
“In contrast to research on average daily intake, studies investigating the impact of drinking pattern have had difficulty consistently demonstrating simultaneously both an increased risk associated with heavy drinking and a protective association with more moderate consumption (Roerecke and Rehm, 2010).”
InfluentialFunctional Benefits of (Modest) Alcohol Consumption
Dunbar, R., Launay, J., Wlodarski, R., Robertson, C., Pearce, E., Carney, J., & MacCarron, P. (2016) · Adaptive Human Behavior and Physiology · doi:10.1007/s40750-016-0058-4 · Cited by 121 · see citing works
“Perhaps because alcohol addiction has serious medical and social consequences, most research on alcohol use has focussed on the effects of over-consumption (Taylor et al. 2005; Easdon et al. 2005; Roerecke and Rehm 2010).”
BackgroundCardiovascular effects of alcohol consumption
Rehm, J. T., & Roerecke, M. (2017) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2017.06.002 · Cited by 113 · see citing works
Self-citationAlcohol-attributable mortality in France
Guérin, S., Laplanche, A., Dunant, A., & Hill, C. (2013) · European Journal of Public Health · doi:10.1093/eurpub/ckt015 · Cited by 111 · see citing works
The Effect of Alcohol on Blood Pressure and Hypertension
Fuchs, F. D., & Fuchs, S. C. P. C. (2021) · Current Hypertension Reports · doi:10.1007/s11906-021-01160-7 · Cited by 108 · see citing works
Anderson, P., Bendtsen, P., Spak, F., Reynolds, J., Drummond, C., Segura, L., Keurhorst, M. N., Palacio-Vieira, J., Wojnar, M., Parkinson, K., et al. (2016) · Addiction · doi:10.1111/add.13476 · Cited by 98 · see citing works
Quantifying the contribution of alcohol to cardiomyopathy: A systematic review
Rehm, J., Hasan, O. S. M., Imtiaz, S., & Neufeld, M. (2017) · Alcohol · doi:10.1016/j.alcohol.2017.01.011 · Cited by 92 · see citing works
Self-citationHistory of lifetime smoking, smoking cessation and cognitive function in the elderly population
Mons, U., Schöttker, B., Müller, H., Kliegel, M., & Brenner, H. (2013) · European Journal of Epidemiology · doi:10.1007/s10654-013-9840-9 · Cited by 91 · see citing works
“cardiovascular diseases [34], were not assessed.”
Mukamal, K. J., Stampfer, M. J., & Rimm, E. B. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00578-3 · Cited by 91 · see citing works
Ischemic Heart Disease Mortality and Morbidity Rates in Former Drinkers: A Meta-Analysis
Roerecke, M., & Rehm, J. T. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq364 · Cited by 88 · see citing works
Self-citationStockwell, T. R., Butt, P. R., Beirness, D. J., Gliksman, L., & Paradis, C. (2011) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2011.00342.x · Cited by 87 · see citing works
Arsandaux, J., Montagni, I., Macalli, M., Bouteloup, V., Tzourio, C., & Galéra, C. (2020) · International Journal of Behavioral Medicine · doi:10.1007/s12529-020-09857-w · Cited by 91 · see citing works
“HRB as follows [5]: (1) behaviors that contribute to unintentional injuries and violence [6, 7]; (2) sexual behaviors related to unintended pregnancy and sexually transmitted infections (including HIV) [8–10]; (3) alcohol and other drug use [11, 12]; (4) tobacco use [2, 13]; (5) unhealthy dietary behaviors [14–16]; an…”
BackgroundChronic heavy drinking and ischaemic heart disease: a systematic review and meta-analysis
Roerecke, M., & Rehm, J. T. (2014) · Open Heart · doi:10.1136/openhrt-2014-000135 · Cited by 83 · see citing works
Self-citationConsensus statement on management of dyslipidemia in Indian subjects
Chandra, K. S., Bansal, M., Nair, T., Iyengar, S. S., Gupta, R., Manchanda, S. C., Mohanan, P. P., Rao, V. D., Manjunath, C. N., Sawhney, J. P. S., et al. (2014) · Indian Heart Journal · doi:10.1016/j.ihj.2014.12.001 · Cited by 84 · see citing works
“However, binge drinking and heavy drinking increase CV mortality.(197) Heavy drinking has also been shown to be associated with metabolic syndrome, through elevation of blood pressure and TG, inmale patients with diabetes.”
BackgroundRecent Advances in Preventive Cardiology and Lifestyle Medicine
Franklin, B. A., & Cushman, M. (2011) · Circulation · doi:10.1161/circulationaha.110.981613 · Cited by 81 · see citing works
Hatzenbuehler, M. L., Slopen, N. B., & McLaughlin, K. A. (2014) · Health Psychology · doi:10.1037/hea0000126 · Cited by 83 · see citing works
Shield, K. D., Gmel, G. E., Kehoe‐Chan, T. A. K., Dawson, D. A., Grant, B. F., & Rehm, J. T. (2013) · PLoS ONE · doi:10.1371/journal.pone.0051923 · Cited by 74 · see citing works
“In order to estimate the number of fatalities from ischemic heart disease, we combined prevalence data on drinking status, binge drinking status, and average daily volume of alcohol consumed [27,28].”
BackgroundSelf-citationScrimshaw, N. S., & Guzmán, M. A. (1964) · BMJ · doi:10.1136/bmj.2.5424.1544 · Cited by 75 · see citing works
Shield, K. D., Gmel, G., Gmel, G., Mäkelä, P., Probst, C., Room, R., & Rehm, J. (2017) · Addiction · doi:10.1111/add.13827 · Cited by 71 · see citing works
“For instance, for people engaged in heavy episodic drinking (consuming ≥ 60 g on at least one occasion monthly), there is no protective effect of alcohol consumption on ischemic cardiovascular diseases [50,51].”
BackgroundSelf-citationAlcohol and the heart: To abstain or not to abstain?
Movva, R., & Figueredo, V. M. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.01.030 · Cited by 63 · see citing works
“drinking was mixed with irregular heavy drinking (>60 g of pure alcohol or > or =5 drinks per occasion at least monthly).[37] Former drinkers compared to long-term abstainers had significantly increased risk for CHD mortality, in a recent metaanalysis.”
BackgroundRehm, J. T., Shield, K. D., Roerecke, M., & Gmel, G. E. (2016) · BMC Public Health · doi:10.1186/s12889-016-3026-9 · Cited by 63 · see citing works
“2) For both IHD and IS, there is evidence that with either irregular or regular heavy drinking occasions, the beneficial effect disappears [2, 6, 8, 14, 16, 32], which must be taken into account even for light to medium drinkers.”
BackgroundMethodInfluentialSelf-citationAlcohol Intake Revisited: Risks and Benefits
Roerecke, M., & Rehm, J. (2012) · Current Atherosclerosis Reports · doi:10.1007/s11883-012-0277-5 · Cited by 58 · see citing works
Self-citationEpisodic Heavy Drinking and 20-Year Total Mortality Among Late-Life Moderate Drinkers
Holahan, C. J., Brennan, P., Schutte, K., Holahan, C. K., & Moos, R. (2014) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12381 · Cited by 53 · see citing works
“Studies that have failed to identify positive health effects associated with moderate alcohol consumption may include a high proportion of episodic heavy drinkers in the study population (Roerecke and Rehm, 2010).”
Dam, M. K., Hvidtfeldt, U. A., Tjønneland, A. M., Overvad, K., Grønbæk, M., & Tolstrup, J. S. (2016) · BMJ · doi:10.1136/bmj.i2314 · Cited by 58 · see citing works
Hingson, R., Heeren, T., Edwards, E. M., & Saitz, R. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1851-1 · Cited by 57 · see citing works
Alcohol: taking a population perspective
Gilmore, W., Chikritzhs, T. N., Stockwell, T. R., Jernigan, D. H., Naimi, T. S., & Gilmore, I. T. (2016) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.70 · Cited by 68 · see citing works
Naimi, T. S., Xuan, Z., Brown, D. W., & Saitz, R. (2012) · Addiction · doi:10.1111/j.1360-0443.2012.04074.x · Cited by 53 · see citing works
Smoking, alcohol and opioids effect on coronary microcirculation: an update overview
Jalali, Z., Khademalhosseini, M., Soltani, N., & Nadimi, A. E. (2021) · BMC Cardiovascular Disorders · doi:10.1186/s12872-021-01990-y · Cited by 50 · see citing works
Shield, K. D., & Rehm, J. T. (2015) · BMC Public Health · doi:10.1186/s12889-015-1818-y · Cited by 48 · see citing works
“Data for the drinking status indicators for 2012, namely lifetime abstainers (those who have not consumed at least one standard drink of alcohol within their lifetime), former drinkers (those who have consumed at least one standard drink of alcohol, but have not done so in the past year), and current drinkers (those w…”
BackgroundMethodInfluentialSelf-citationBellis, M. A., Hughes, K. E., Jones, L., Morleo, M., Nicholls, J. Q., McCoy, E., Webster, J., & Sumnall, H. R. (2015) · BMC Medicine · doi:10.1186/s12916-015-0337-0 · Cited by 48 · see citing works
“Further, while the benefits of alcohol consumption on reducing risk of ischaemic heart disease remain contested, even potential cardio-protective benefits are absent when individuals binge once a month or more (>60 g of pure alcohol in one session [37]).”
BackgroundJCS 2023 Guideline on the Primary Prevention of Coronary Artery Disease
Fujiyoshi, A., Kohsaka, S., Hata, J., Hara, M., Kai, H., Masuda, D., Miyamatsu, N., Nishio, Y., Ogura, M., Sata, M., et al. (2024) · Circulation Journal · doi:10.1253/circj.cj-23-0285 · Cited by 47 · see citing works
Explaining Disability Trends in the U.S. Elderly and Near‐Elderly Population
Chen, Y., & Sloan, F. A. (2015) · Health Services Research · doi:10.1111/1475-6773.12284 · Cited by 46 · see citing works
“Third, heavy drinking and smoking are leading risk factors for heart disease, respiratory disease, and stroke (Sundell et al. 2008; Roerecke and Rehm 2010; Shah and Cole 2010), and Address correspondence to Frank A. Sloan, Ph.D., J. Alexander McMahon Professor of Health Policy andManagement and…”
BackgroundEstimating uncertainty of alcohol-attributable fractions for infectious and chronic diseases
Gmel, G. E., Shield, K. D., Frick, H., Kehoe, T., Gmel, G., & Rehm, J. T. (2011) · BMC Medical Research Methodology · doi:10.1186/1471-2288-11-48 · Cited by 44 · see citing works
“As some of the non-linear nature may be caused by other dimensions of alcohol consumption (for example, irregular heavy drinking occasions in the case of ischemic diseases) [24,25], it will not be enough to just conduct more epidemiological studies into the impact of average volume of alcohol consumption on the incide…”
BackgroundSelf-citationA burden of proof study on alcohol consumption and ischemic heart disease
Carr, S., Bryazka, D., McLaughlin, S. A., Zheng, P., Bahadursingh, S., Aravkin, A. Y., Hay, S. I., Lawlor, H. R., Mullany, E. C., Murray, C. J. L., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-47632-7 · Cited by 45 · see citing works
“Aprimarylimitationoftheanalysisis thatitwasnotpossible,duetoinsuf fi cientdata,todifferentiatetheestimatedalcohol-IHDrelationshipbyalcoholusesubtype – thatis, by average consumption characterized by frequency and quantity, by HED, or by beverage type – and to then compare subtype-speci fi c relationships across study de…”
InfluentialSelf-citationRoerecke, M., Greenfield, T. K., Kerr, W. C., Bondy, S. J., Cohen, J., & Rehm, J. T. (2011) · International Journal of Epidemiology · doi:10.1093/ije/dyr129 · Cited by 43 · see citing works
Self-citationBinge Drinking and Blood Pressure: Cross-Sectional Results of the HAPIEE Study
Pająk, A., Szafraniec, K., Kubínová, R., Malyutina, S. K., Peasey, A., Pikhart, H., IuP, N., Marmot, M. G., & Bobák, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065856 · Cited by 43 · see citing works
“There is emerging evidence that episodic consumption of high amounts of alcohol (binge drinking) is associated with high risk of coronary heart disease [12], stroke [13] and metabolic syndrome [14].”
BackgroundResultWhite, A., McKee, M., de Sousa, B. C., de Visser, R. O., Hogston, R., Madsen, S. A., MAKARA, P., Richardson, N., ski, W. Z., & Raine, G. (2013) · European Journal of Public Health · doi:10.1093/eurpub/ckt076 · Cited by 43 · see citing works
“(30-32) It is anticipated that this will be an increasingly important factor in Western death rates.(33)”
BackgroundRehm, J. T., & Patra, J. (2011) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2011.00395.x · Cited by 43 · see citing works
Self-citationThe Association Between Alcohol Consumption Patterns and Adherence to Food Consumption Guidelines
Martín, J. V., Galán, I., & Rodríguez‐Artalejo, F. (2011) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2011.01559.x · Cited by 41 · see citing works
Romelsjö, A., Allebeck, P., Andréasson, S., & Leifman, A. (2012) · Alcohol and Alcoholism · doi:10.1093/alcalc/ags021 · Cited by 40 · see citing works
J‐curve revisited: cardiovascular benefits of moderate alcohol use cannot be dismissed
Thompson, P. L. (2013) · The Medical Journal of Australia · doi:10.5694/mja12.10922 · Cited by 40 · see citing works
Graff‐Iversen, S., Jansen, M. D., Hoff, D. A., Høiseth, G., Knudsen, G. P., Magnus, P. M., Mørland, J. G., Normann, P. T., Næss, Ø., & Tambs, K. (2012) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2012-201564 · Cited by 40 · see citing works
Murphy, A., Johnson, C. O., Roth, G. A., Forouzanfar, M. H., Naghavi, M., Ng, M., Вачиковна, П. Н., Vos, T., Murray, C. J. L., & Moran, A. E. (2017) · Heart · doi:10.1136/heartjnl-2016-311142 · Cited by 42 · see citing works
Rehm, J. T., Rehm, M. X., Shield, K. D., Gmel, G. E., & Gual, A. (2013) · Adicciones · doi:10.20882/adicciones.67 · Cited by 39 · see citing works
Self-citationRehm, J. T., & Scafato, E. (2011) · Addiction · doi:10.1111/j.1360-0443.2010.03323.x · Cited by 39 · see citing works
“However, there is also a detrimental effect of heavy drinking occasions when overall drinking is light to moderate, particularly for injury and cardiovascular events [11,24–26].”
BackgroundSelf-citationZyriax, B.-C., Lau, K., Klähn, T., Boeing, H., Völzke, H., & Windler, E. E. T. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.144 · Cited by 40 · see citing works
Marmet, S., Rehm, J. T., Gmel, G. E., Frick, H., & Gmel, G. E. (2014) · Swiss Medical Weekly · doi:10.4414/smw.2014.13947 · Cited by 39 · see citing works
Self-citationToward a unifying theory of dysregulated behaviors
Bresin, K. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101885 · Cited by 38 · see citing works
CONNOR, J. L., Kydd, R. M., Shield, K. D., & Rehm, J. T. (2015) · PubMed · Cited by 37 · see citing works
Self-citationMcCann, M., Perra, O., McLaughlin, A., McCartan, C. J., & Higgins, K. (2015) · Addiction · doi:10.1111/add.13258 · Cited by 36 · see citing works
“…between age of onset and later chronic alcohol problems [2,3], early use is predictive of future drinking patterns [4], which can contribute to long-term health outcomes [5 – 7], delinquency [8 – 10], mental health problems and risky sexual behaviour [11,12] and poor academic performance [8,13,14].”
BackgroundMyocardial infarction and alcohol consumption: A case-control study
Ilić, M., Grujičić, S. Š., Ristic, B. M., & Ilić, I. (2018) · PLoS ONE · doi:10.1371/journal.pone.0198129 · Cited by 36 · see citing works
Mortality and potential years of life lost attributable to alcohol consumption in Canada in 2005
Shield, K. D., Taylor, B., Kehoe, T., Patra, J., & Rehm, J. T. (2012) · BMC Public Health · doi:10.1186/1471-2458-12-91 · Cited by 33 · see citing works
“While restrictions on volume may not be important for certain diseases, patterns of drinking impact the risk of diseases such as ischemic heart disease and other cardiovascular diseases [4,26,27].”
BackgroundSelf-citationPredicting heavy episodic drinking using an extended temporal self-regulation theory
Black, N., Mullan, B. A., & Sharpe, L. (2017) · Addictive Behaviors · doi:10.1016/j.addbeh.2017.04.017 · Cited by 36 · see citing works
Kabashi, S., Vindenes, V., Bryun, E. A., Ea, K., Надеждин, А. В., Tetenova, E. J., Kolgashkin, A. J., Петухов, А. Е., Переходов, С. Н., Davydova, E. N., et al. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107588 · Cited by 35 · see citing works
Mougharbel, F., Sampasa‐Kanyinga, H., Heidinger, B. A., Corace, K., Hamilton, H. A., & Goldfield, G. S. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.680028 · Cited by 35 · see citing works
Per capita alcohol consumption and suicide mortality in a panel of US states from 1950 to 2002
Kerr, W. C., Subbaraman, M. S., & Ye, Y. (2011) · Drug and Alcohol Review · doi:10.1111/j.1465-3362.2011.00306.x · Cited by 34 · see citing works
Associations between heavy alcohol drinking and lipid-related indices in middle-aged men
Wakabayashi, I. (2013) · Alcohol · doi:10.1016/j.alcohol.2013.10.001 · Cited by 34 · see citing works
- Authors
- Roerecke, M., & Rehm, J.
- Affiliations
- Centre for Addiction and Mental Health (CA)
- ORCID
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-02-08
- Volume
- 171
- Issue
- 6
- Pages
- 633-644
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2033435847
- Cited by
- 307
- References
- 99
- Citations by year
- 2026: 2 · 2025: 11 · 2024: 11 · 2023: 10 · 2022: 5 · 2021: 20 · 2020: 17 · 2019: 11 · 2018: 12 · 2017: 29 · 2016: 33 · 2015: 29 · 2014: 25 · 2013: 29 · 2012: 27
- FWCI
- 3.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Kela
- University of Toronto
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Keywords
- binge drinking, ischemic heart disease, alcohol consumption, moderate drinking, cardioprotection, alcohol intoxication, cardiovascular risk
- MeSH terms
- Alcohol Drinking, Alcoholic Intoxication, Humans, Regression Analysis, Risk Factors, Myocardial Ischemia
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