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The Ensembl gene annotation system
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The main difference between NCBI's EGAP and Ensembl's Gene annotation system is the way in which they incorporate several lines of evidence into the end gene model results.
“The main difference between NCBI’s Eukaryotic Genome Annotation Pipeline (EGAP) and Ensembl’s Gene annotation system is the way in which they incorporate several lines of evidence into the end gene model results.”
From Annotation matters: the effect of structural gene annotation on orthology inference (2025) · cites this paper as Aken et al. 2016
Ensembl and NCBI eukaryotic gene annotation pipelines have stringent requirements to include a solely ab initio model in their final gene set.
“Indeed, the Ensembl and NCBI eukaryotic gene annotation pipelines have stringent requirements to include a solely ab initio model in their final gene set (Aken et al. 2016, Goldfarb et al. 2025).”
From Annotation matters: the effect of structural gene annotation on orthology inference (2025) · cites this paper as Aken et al. 2016
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Self-citationLoss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
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Metadata
- Authors
- Aken, B. L., Ayling, S., Barrell, D., Clarke, L., Curwen, V., Fairley, S., Fernandez Banet, J., Billis, K., García Girón, C., Hourlier, T., Howe, K., Kähäri, A., Kokocinski, F., Martin, F. J., Murphy, D. N., Nag, R., Ruffier, M., Schuster, M., Tang, Y. A., Vogel, J.-H., White, S., Zadissa, A., Flicek, P., & Searle, S. M. J.
- Venue
- Database
- Publisher
- Oxford University Press (OUP)
- Published
- 2016
- Volume
- 2016
- Pages
- baw093
- ISSN
- 1758-0463
- PMC
- PMC4919035
- Cited by
- 1,086
- References
- 17
- Language
- en
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