Polysaccharide Production by Lactic Acid Bacteria: From Genes to Industrial Applications

Zeidan, Ahmad A.; Poulsen, Vera Kuzina; Janzen, Thomas; Buldo, Patrizia; Derkx, Patrick M. F.; Øregaard, Gunnar; Neves, Ana Rute

doi:10.1093/femsre/fux017

Cited by 326Polysaccharides Composition and ApplicationsProbiotics and Fermented FoodsBiopolymer Synthesis and Applications

Polysaccharide Production by Lactic Acid Bacteria: From Genes to Industrial Applications

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Zeidan, Ahmad A., Poulsen, Vera Kuzina, Janzen, Thomas, Buldo, Patrizia, Derkx, Patrick M. F., Øregaard, Gunnar, Neves, Ana Rute·2017·FEMS Microbiology Reviews

DOI 10.1093/femsre/fux017

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Abstract

The ability to produce polysaccharides with diverse biological functions is widespread in bacteria. In lactic acid bacteria (LAB), production of polysaccharides has long been associated with the technological, functional and health-promoting benefits of these microorganisms. In particular, the capsular polysaccharides and exopolysaccharides have been implicated in modulation of the rheological properties of fermented products. For this reason, screening and selection of exocellular polysaccharide-producing LAB has been extensively carried out by academia and industry. To further exploit the ability of LAB to produce polysaccharides, an in-depth understanding of their biochemistry, genetics, biosynthetic pathways, regulation and structure-function relationships is mandatory. Here, we provide a critical overview of the latest advances in the field of glycosciences in LAB. Surprisingly, the understanding of the molecular processes involved in polysaccharide synthesis is lagging behind, and has not accompanied the increasing commercial value and application potential of these polymers. Seizing the natural diversity of polysaccharides for exciting new applications will require a concerted effort encompassing in-depth physiological characterization of LAB at the systems level. Combining high-throughput experimentation with computational approaches, biochemical and structural characterization of the polysaccharides and understanding of the structure-function-application relationships is essential to achieve this ambitious goal.

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Genes of the Wzy-dependent pathway have been reported only in Weisella, Leuconostoc, Lactiplantibacillus, Pediococcus and Streptococcus genera.
“Genes of the Wzy-dependent pathway have been reported only in Weisella, Leuconostoc, Lactiplantibacillus, Pediococcus and Streptococcus genera.”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [16]
The Comparative Genomics section (page not provided) identifies Wzy polymerase and Wzx flippase genes in Lactococcus lactis, a genus absent from the claim's exclusive list. It also distinguishes the listed genera as those with reported sucrase-encoding genes, not the only genera with Wzy-dependent pathway genes. (LLM, conf=0.90)
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In S. thermophilus and Lb. bulgaricus, HePS production is favored under optimal growth conditions.
“in S. thermophilus and Lb. bulgaricus HePS production is favored under optimal growth conditions”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [16]
The ‘Regulation of polysaccharide synthesis’ section says production in some strains of S. thermophilus and Lb. bulgaricus appears to peak under conditions favoring optimal growth. The claim omits ‘some strains’ and presents this tentative observation as a general finding for both species. (LLM, conf=0.88)
Experimental — accuracy not yet measured
In Lacticaseibacillus casei, medium composition influenced exocellular polysaccharide production and its sugar composition.
“in Lacticaseibacillus (Lcb.) casei, medium composition influenced exocellular polysaccharide production and its sugar composition.”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [16]
Polysaccharide production is influenced by pH, temperature, amino acids, vitamins and minerals.
“Polysaccharide production is also influenced by pH, temperature, aminoacids, vitamins and minerals [16].”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [16]

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The biofilm matrix
Flemming, H.-C., & Wingender, J. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2415 · Cited by 10,137 · see citing works
The carbohydrate-active enzymes database (CAZy) in 2013
Lombard, V., Ramulu, H. G., Drula, É., Coutinho, P. M., & Henrissat, B. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1178 · Cited by 6,355 · see citing works
Biosynthesis and Assembly of Capsular Polysaccharides in Escherichia coli
Whitfield, C. (2006) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.75.103004.142545 · Cited by 993 · see citing works
Carbohydrate metabolism in lactic acid bacteria
Kandler, O. (1983) · Antonie van Leeuwenhoek · doi:10.1007/bf00399499 · Cited by 901 · see citing works
Heteropolysaccharides from lactic acid bacteria
Vuyst, L. D., & Degeest, B. (1999) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1999.tb00395.x · Cited by 840 · see citing works
Advances in bacterial exopolysaccharides: from production to Biotechnological applications
Freitas, F., Alves, V. D., & Reis, M. A. M. (2011) · Trends in Biotechnology · doi:10.1016/j.tibtech.2011.03.008 · Cited by 804 · see citing works
Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes
Bentley, S. D., Aanensen, D. M., Mavroidi, A., Saunders, D., Rabbinowitsch, E., Collins, M. D., Donohoe, K., Harris, D. J., Murphy, L., Quail, M. A., et al. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020031 · Cited by 759 · see citing works
Pneumococcal Capsules and Their Types: Past, Present, and Future
Geno, K. A., Gilbert, G. L., Song, J. Y., Skovsted, I. C., Klugman, K. P., Jones, C., Konradsen, H. B., & Nahm, M. H. (2015) · Clinical Microbiology Reviews · doi:10.1128/cmr.00024-15 · Cited by 732 · see citing works
An overview of the functionality of exopolysaccharides produced by lactic acid bacteria
Ruas‐Madiedo, P., Hugenholtz, J., & Zoon, P. (2002) · International Dairy Journal · doi:10.1016/s0958-6946(01)00160-1 · Cited by 625 · see citing works
Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies
Schmid, J., Sieber, V., & Rehm, B. H. A. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00496 · Cited by 616 · see citing works
Microbial Exopolysaccharides: Main Examples of Synthesis, Excretion, Genetics and Extraction
Donot, F., Fontana, A., Baccou, J. C., & Schorr-Galindo, S. (2012) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2011.08.083 · Cited by 605 · see citing works
Exopolysaccharide-deficient mutants of Rhizobium meliloti that form ineffective nodules.
Leigh, J. A., Signer, E. R., & Walker, G. C. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.18.6231 · Cited by 593 · see citing works
Polysaccharide protein interactions
de Kruif, C. G., & Tuinier, R. (2001) · Food Hydrocolloids · doi:10.1016/s0268-005x(01)00076-5 · Cited by 527 · see citing works
Exopolysaccharides from lactic acid bacteria: perspectives and challenges
Welman, A. D., & Maddox, I. S. (2003) · Trends in biotechnology · doi:10.1016/s0167-7799(03)00107-0 · Cited by 523 · see citing works
Bacterial polysaccharide synthesis and gene nomenclature
Reeves, P. R., Hobbs, M., Valvano, M. A., Skurnik, M., Whitfield, C., Coplin, D. L., Kido, N., Klena, J. D., Maskell, D. J., Raetz, C. R. H., et al. (1996) · Trends in Microbiology · doi:10.1016/s0966-842x(97)82912-5 · Cited by 489 · see citing works
Exocellular polysaccharides produced by lactic acid bacteria
Cerning, J. (1990) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1990.tb04883.x · Cited by 470 · see citing works
Invited Commentary: A calculation of all possible oligosaccharide isomers both branched and linear yields 1.05 × 1012 structures for a reducing hexasaccharide: the Isomer Barrier to development of single-method saccharide sequencing or synthesis systems
Laine, R. A. (1994) · Glycobiology · doi:10.1093/glycob/4.6.759 · Cited by 466 · see citing works
Structure-Function Relationships of Glucansucrase and Fructansucrase Enzymes from Lactic Acid Bacteria
van Hijum, S. A. F. T., Kralj, S., Ozimek, L. K., Dijkhuizen, L., & van Geel-Schutten, I. H. (2006) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.70.1.157-176.2006 · Cited by 466 · see citing works
Invited Review: Methods for the Screening, Isolation, and Characterization of Exopolysaccharides Produced by Lactic Acid Bacteria
Ruas-Madiedo, P., & de los Reyes-Gavilán, C. G. (2005) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(05)72750-8 · Cited by 456 · see citing works
Exopolysaccharides Produced by Lactic Acid Bacteria: From Health-Promoting Benefits to Stress Tolerance Mechanisms
Caggianiello, G., Kleerebezem, M., & Spano, G. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7471-2 · Cited by 396 · see citing works
Recent Developments in the Biosynthesis and Applications of Heteropolysaccharides from Lactic Acid Bacteria
De Vuyst, L., De Vin, F., Vaningelgem, F., & Degeest, B. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00114-5 · Cited by 391 · see citing works
Production, Properties, and Industrial Food Application of Lactic Acid Bacteria-Derived Exopolysaccharides
Zannini, E., Waters, D. M., Coffey, A., & Arendt, E. K. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-7172-2 · Cited by 371 · see citing works
The love–hate relationship between bacterial polysaccharides and the host immune system
Mazmanian, S. K., & Kasper, D. L. (2006) · Nature reviews. Immunology · doi:10.1038/nri1956 · Cited by 357 · see citing works
New insights in the molecular biology and physiology of revealed by comparative genomics
Pascal Hols, A., Hancy, F., Fontaine, L., Grossiord, B., Prozzi, D., Leblond‐Bourget, N., Decaris, B., Bolotin, A., Delorme, C., & Ehrlich, S. D. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2005.04.008 · Cited by 354 · see citing works
Present and future medical applications of microbial exopolysaccharides
Moscovici, M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.01012 · Cited by 331 · see citing works
Characterization of a Novel Exopolysaccharide with Antitumor Activity from Lactobacillus plantarum 70810
Wang, K., Li, W., Rui, X., Chen, X., Jiang, M., & Dong, M. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2013.10.036 · Cited by 325 · see citing works
Identification and characterization of the eps (Exopolysaccharide) gene cluster from Streptococcus thermophilus Sfi6
Stingele, F., Neeser, J., & Mollet, B. (1996) · Journal of Bacteriology · doi:10.1128/jb.178.6.1680-1690.1996 · Cited by 319 · see citing works
Capsules of Streptococcus pneumoniae and Other Bacteria: Paradigms for Polysaccharide Biosynthesis and Regulation
Yother, J. (2010) · Annual Review of Microbiology · doi:10.1146/annurev.micro.62.081307.162944 · Cited by 307 · see citing works
Synthesis of bacterial polysaccharides via the Wzx/Wzy-dependent pathway
Islam, S. T., & Lam, J. S. (2014) · Canadian Journal of Microbiology · doi:10.1139/cjm-2014-0595 · Cited by 288 · see citing works
A widespread family of bacterial cell wall assembly proteins
Kawai, Y., Marles‐Wright, J., Cleverley, R. M., Emmins, R., Ishikawa, S., Kuwano, M., Heinz, N., Bui, N. K., Hoyland, C. N., Ogasawara, N., et al. (2011) · The EMBO Journal · doi:10.1038/emboj.2011.358 · Cited by 275 · see citing works
Structural elucidation and antioxidant activities of exopolysaccharides from Lactobacillus helveticus MB2-1
Li, W., Ji, J., Chen, X., Jiang, M., Rui, X., & Dong, M. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.11.053 · Cited by 271 · see citing works
Biochemistry, Genetics, and Applications of Exopolysaccharide Production in Streptococcus thermophilus: A Review
Broadbent, J. R., McMahon, D. J., Welker, D. L., Oberg, C. J., & Moineau, S. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73619-4 · Cited by 271 · see citing works
Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase
Lebeer, S., Verhoeven, T. L. A., Francius, G., Schoofs, G., Lambrichts, I., Dufrêne, Y. F., Vanderleyden, J., & Keersmaecker, S. C. J. D. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02919-08 · Cited by 271 · see citing works
Microstructure and Rheology of Yogurt Made with Cultures Differing Only in Their Ability to Produce Exopolysaccharides
Hassan, A. N., Ipsen, R., Janzen, T., & Qvist, K. B. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73748-5 · Cited by 267 · see citing works
Self-citation
Lactic acid bacteria : microbiological and functional aspects
Lahtinen, S. J. (2012) · CRC Press eBooks · Cited by 263 · see citing works
Molecular characterization of the plasmid‐encoded eps gene cluster essential for exopolysaccharide biosynthesis in Lactococcus lactis
van Kranenburg, R., Marugg, J. D., van Swam, I. I., Willem, N. J., & de Vos, W. M. (1997) · Molecular Microbiology · doi:10.1046/j.1365-2958.1997.3521720.x · Cited by 262 · see citing works
Carbon Source Requirements for Exopolysaccharide Production by Lactobacillus casei CG11 and Partial Structure Analysis of the Polymer
Cerning, J., Renard, C. M. G. C., Thibault, J.-F., Bouillanne, C., Landon, M., Desmazeaud, M., & Topisirovic, L. (1994) · Applied and Environmental Microbiology · doi:10.1128/aem.60.11.3914-3919.1994 · Cited by 251 · see citing works
Production, purification and structural characterization of an exopolysaccharide produced by a probiotic Lactobacillus plantarum MTCC 9510
Ismail, B., & Nampoothiri, K. M. (2010) · Archives of Microbiology · doi:10.1007/s00203-010-0636-y · Cited by 241 · see citing works
Production of exopolysaccharides by lactic acid bacteria and dairy propionibacteria
Cerning, J. (1995) · Le Lait · doi:10.1051/lait:19954-536 · Cited by 240 · see citing works
Influence of exopolysaccharides on the structure, texture, stability and sensory properties of yoghurt and related products
Mende, S., Rohm, H., & Jaros, D. (2015) · International Dairy Journal · doi:10.1016/j.idairyj.2015.08.002 · Cited by 238 · see citing works
In Situ Production of Exopolysaccharides during Sourdough Fermentation by Cereal and Intestinal Isolates of Lactic Acid Bacteria
Tieking, M., Korakli, M., Ehrmann, M. A., Gänzle, M. G., & Vogel, R. F. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.2.945-952.2003 · Cited by 233 · see citing works
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: A regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier
Lazarevic, V., Margot, P., Soldo, B., & Karamata, D. (1992) · Journal of General Microbiology · doi:10.1099/00221287-138-9-1949 · Cited by 227 · see citing works
Production by and isolation of exopolysaccharides from Streptococcus thermophilus grown in a milk medium and evidence for their growth-associated biosynthesis
Vuyst, L. D., Vanderveken, de Ven, V., & Degeest (1998) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.1998.00445.x · Cited by 226 · see citing works
Sugar-Coated: Exopolysaccharide Producing Lactic Acid Bacteria for Food and Human Health Applications
Ryan, P. M., Ross, R. P., Fitzgerald, G. F., Caplice, N. M., & Stanton, C. (2015) · Food & Function · doi:10.1039/c4fo00529e · Cited by 221 · see citing works
Biodiversity of Exopolysaccharides Produced by Streptococcus thermophilus Strains Is Reflected in Their Production and Their Molecular and Functional Characteristics
Vaningelgem, F., Zamfir, M., Mozzi, F., Adriany, T., Vancanneyt, M., Swings, J., & De Vuyst, L. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.2.900-912.2004 · Cited by 221 · see citing works
Tyrosine phosphorylation of CpsD negatively regulates capsular polysaccharide biosynthesis in Streptococcus pneumoniae
Morona, J. K., Paton, J. C., Miller, D. C., & Morona, R. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01808.x · Cited by 221 · see citing works
Exopolysaccharides from Sourdough Lactic Acid Bacteria
Galle, S., & Arendt, E. K. (2013) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2011.617474 · Cited by 219 · see citing works
Food and health applications of exopolysaccharides produced by lactic acid bacteria
JB Prajapat, A. P. (2013) · Advances in Dairy Research · doi:10.4172/2329-888x.1000107 · Cited by 219 · see citing works
Polysaccharide–protein interactions in dairy matrices, control and design of structures
Corredig, M., Sharafbafi, N., & Kristo, E. (2011) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2011.05.014 · Cited by 215 · see citing works
Bacterial Glycobiology: Rhamnose-Containing Cell Wall Polysaccharides in Gram-Positive Bacteria
Mistou, M.-Y., Sutcliffe, I. C., & van Sorge, N. M. (2016) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuw006 · Cited by 215 · see citing works
Biopolymers from Lactic Acid Bacteria. Novel Applications in Foods and Beverages
Torino, M. I., Font de Valdez, G., & Mozzi, F. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00834 · Cited by 201 · see citing works
Screening and characterization of Lactobacillus strains producing large amounts of exopolysaccharides
van Geel-Schutten, G. H., Flesch, F. M., ten Brink, B., Smith, M. R., & Dijkhuizen, L. (1998) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051353 · Cited by 196 · see citing works
Physical characteristics of yoghurts made using exopolysaccharide-producing starter cultures and varying casein to whey protein ratios
Amatayakul, T., Halmos, A. L., Sherkat, F., & Shah, N. P. (2005) · International Dairy Journal · doi:10.1016/j.idairyj.2005.01.004 · Cited by 195 · see citing works
Genetics of lactose utilization in lactic acid bacteria
de Vos, W. M., & Vaughan, E. E. (1994) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1994.tb00136.x · Cited by 192 · see citing works
Isolation and Characterization of Exopolysaccharides from Slime-Forming Mesophilic Lactic Acid Bacteria
Cerning, J., Bouillanne, C., LANDON, M., & Desmazeaud, M. (1992) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(92)77805-9 · Cited by 192 · see citing works
Effects of exopolysaccharide-producing strains of thermophilic lactic acid bacteria on the texture of stirred yoghurt
Marshall, V. M., & Rawson, H. L. (1999) · International Journal of Food Science & Technology · doi:10.1046/j.1365-2621.1999.00245.x · Cited by 181 · see citing works
Overview on sugar metabolism and its control in – The input from in vivo NMR
Neves, A. R., Pool, W., Kok, J., Kuipers, O. P., & Santos, H. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2005.04.005 · Cited by 180 · see citing works
Self-citation
From physiology to systems metabolic engineering for the production of biochemicals by lactic acid bacteria
Gaspar, P., Carvalho, A. L., Vinga, S., Santos, H., & Neves, A. R. (2013) · Biotechnology Advances · doi:10.1016/j.biotechadv.2013.03.011 · Cited by 178 · see citing works
Self-citation
Rheological Properties of Nonfat Yogurt Stabilized Using Lactobacillus delbrueckii ssp. bulgaricus Producing Exopolysaccharide or Using Commercial Stabilizer Systems
Hess, S., Roberts, R., & Ziegler, G. R. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)75933-2 · Cited by 178 · see citing works
Cell Surface of Lactococcus lactis Is Covered by a Protective Polysaccharide Pellicle
Chapot, M.-P., VINOGRADOV, E. V., Sadovskaya, I., André, G., Mistou, M., Trieu‐Cuot, P., Furlan, S., Bidnenko, E., Courtin, P., Péchoux, C., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.082958 · Cited by 176 · see citing works
Biochemical and Structural Characterization of the Glucan and Fructan Exopolysaccharides Synthesized by the Lactobacillus reuteri Wild-Type Strain and by Mutant Strains
van Geel-Schutten, G. H., Faber, E. J., Smit, E., Bonting, K., Smith, M. R., ten Brink, B., Kamerling, J. P., Vliegenthart, J. F. G., & Dijkhuizen, L. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.7.3008-3014.1999 · Cited by 176 · see citing works
Effects of pH, Temperature, Supplementation with Whey Protein Concentrate, and Adjunct Cultures on the Production of Exopolysaccharides by Streptococcus thermophilus 1275
Zisu, B., & Shah, N. P. (2003) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(03)73944-7 · Cited by 175 · see citing works
Exopolysaccharides from cereal-associated lactobacilli
Tieking, M., & Gänzle, M. G. (2005) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2004.02.015 · Cited by 175 · see citing works
Functional Analysis in Type Ia Group B Streptococcusof a Cluster of Genes Involved in Extracellular Polysaccharide Production by Diverse Species of Streptococci
Cieslewicz, M. J., Kasper, D. L., Wang, Y., & Wessels, M. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m005702200 · Cited by 162 · see citing works
Biotechnology of Lactic Acid Bacteria
Kowalczyk, M., Pérez, B. M., García, M. F., & Aleksandrzak‐Piekarczyk, T. (2015) · Wiley eBooks · doi:10.1002/9781118868386 · Cited by 159 · see citing works
Depletion-Induced Phase Separation of Aggregated Whey Protein Colloids by an Exocellular Polysaccharide
Tuinier, R., Dhont, J. K. G., & de Kruif, C. G. (1999) · Langmuir · doi:10.1021/la990202c · Cited by 152 · see citing works
Biofilm Formation by the Fish Pathogen Flavobacterium columnare: Development and Parameters Affecting Surface Attachment
Cai, W. C., Fuente, L. D. L., & Arias, C. R. (2013) · Applied and Environmental Microbiology · doi:10.1128/aem.01192-13 · Cited by 151 · see citing works
Structural characterization and bioactivity of released exopolysaccharides from Lactobacillus plantarum 70810
Wang, K., Li, W., Rui, X., Chen, X., Jiang, M., & Dong, M. (2014) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2014.02.056 · Cited by 150 · see citing works
Enhanced Exopolysaccharide Production by Metabolic Engineering of Streptococcus thermophilus
Levander, F., Svensson, M., & Rådström, P. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.2.784-790.2002 · Cited by 148 · see citing works
Indication that the Nitrogen Source Influences Both Amount and Size of Exopolysaccharides Produced by Streptococcus thermophilus LY03 and Modelling of the Bacterial Growth and Exopolysaccharide Production in a Complex Medium
Degeest, B., & Vuyst, L. D. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.7.2863-2870.1999 · Cited by 148 · see citing works
Sugar catabolism and its impact on the biosynthesis and engineering of exopolysaccharide production in lactic acid bacteria
Boels, I. C., Kranenburg, R. V., Hugenholtz, J., Kleerebezem, M., & de Vos, W. M. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00116-9 · Cited by 147 · see citing works
Correlation of Activities of the Enzymes α-Phosphoglucomutase, UDP-Galactose 4-Epimerase, and UDP-Glucose Pyrophosphorylase with Exopolysaccharide Biosynthesis by Streptococcus thermophilus LY03
Degeest, B., & Vuyst, L. D. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.8.3519-3527.2000 · Cited by 147 · see citing works
Positive Correlation between Tyrosine Phosphorylation of CpsD and Capsular Polysaccharide Production inStreptococcus pneumoniae
Bender, M. H., Cartee, R. T., & Yother, J. (2003) · Journal of Bacteriology · doi:10.1128/jb.185.20.6057-6066.2003 · Cited by 147 · see citing works
Bacterial tyrosine kinases: evolution, biological function and structural insights
Grangeasse, C., Nessler, S., & Mijakovic̀, I. (2012) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0424 · Cited by 147 · see citing works
Diversity of Heteropolysaccharide-Producing Lactic Acid Bacterium Strains and Their Biopolymers
Mozzi, F., Vaningelgem, F., Hebert, E. M., der Meulen, R. V., Foulquié-Moreno, M. R., de Valdez, G. F., & Vuyst, L. D. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.02780-05 · Cited by 145 · see citing works
Regulation of Exopolysaccharide Production by Lactococcus lactis subsp. cremoris by the Sugar Source
Looijesteijn, P. J., Boels, I. C., Kleerebezem, M., & Hugenholtz, J. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.11.5003-5008.1999 · Cited by 145 · see citing works
The Sweet Tooth of Bacteria: Common Themes in Bacterial Glycoconjugates
Tytgat, H. L. P., & Lebeer, S. (2014) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00007-14 · Cited by 143 · see citing works
Bacterial Polysaccharides - Current Innovations and Future Trends
Ullrich, M. S. (2009) · Caister Academic Press eBooks · doi:10.13140/2.1.1992.0321 · Cited by 142 · see citing works
Role of Streptococcus thermophilus MR-1C Capsular Exopolysaccharide in Cheese Moisture Retention
Low, D., Ahlgren, J. A., Horne, D. S., McMahon, D. J., Oberg, C. J., & Broadbent, J. R. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.6.2147-2151.1998 · Cited by 142 · see citing works
The exopolysaccharides produced by Streptococcus thermophilus Rs and Sts have the same repeating unit but differ in viscosity of their milk cultures
Faber, E. J., Zoon, P., Kamerling, J. P., & Vliegenthart, J. F. G. (1998) · Carbohydrate Research · doi:10.1016/s0008-6215(98)00189-x · Cited by 139 · see citing works
Nucleotide sequence analysis of genes essential for capsular polysaccharide biosynthesis in Streptococcus pneumoniae type 19F
Guidolin, A., Morona, J. K., Morona, R., et al. (1994) · Infection and Immunity · doi:10.1128/iai.62.12.5384-5396.1994 · Cited by 137 · see citing works
Predicted Functions and Linkage Specificities of the Products of theStreptococcus pneumoniaeCapsular Biosynthetic Loci
Aanensen, D. M., Mavroidi, A., Bentley, S. D., Reeves, P. R., & Spratt, B. G. (2007) · Journal of Bacteriology · doi:10.1128/jb.00837-07 · Cited by 137 · see citing works
Heterofermentative pattern and exopolysaccharide production by Lactobacillus helveticus ATCC 15807 in response to environmental pH
Torino, M. I., Taranto, M. P., Sesma, F. J. M., & de Valdez, G. F. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01450.x · Cited by 135 · see citing works
Exopolysaccharide-producing Streptococcus thermophilus strains as functional starter cultures in the production of fermented milks
Vuyst, L. D., Zamfir, M., Mozzi, F., Adriany, T., Marshall, V. M., Degeest, B., & Vaningelgem, F. (2003) · International Dairy Journal · doi:10.1016/s0958-6946(03)00105-5 · Cited by 135 · see citing works
Structure and Biosynthesis of Two Exopolysaccharides Produced by Lactobacillus johnsonii FI9785
Dertli, E., Colquhoun, I. J., Gunning, A. P., Bongaerts, R. J., Le Gall, G., Bonev, B. B., Mayer, M. J., & Narbad, A. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.507418 · Cited by 134 · see citing works
Influence of fructose and glucose on the production of exopolysaccharides and the activities of enzymes involved in the sugar metabolism and the synthesis of sugar nucleotides in Lactobacillus delbrueckii subsp. bulgaricus NCFB 2772
Grobben, G. J., Smith, M. R., Sikkema, J., & de Bont, J. A. M. (1996) · Applied Microbiology and Biotechnology · doi:10.1007/s002530050817 · Cited by 133 · see citing works
Molecular organization and functionality of exopolysaccharide gene clusters in lactic acid bacteria
Jolly, L., & Stingele, F. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00117-0 · Cited by 133 · see citing works
Sensory and rheological screening of exopolysaccharide producing strains of bacterial yoghurt cultures
Folkenberg, D. M., Dejmek, P., Skriver, A., Guldager, H. S., & Ipsen, R. (2005) · International Dairy Journal · doi:10.1016/j.idairyj.2004.10.013 · Cited by 132 · see citing works
Comparison of the Functionality of Exopolysaccharides Produced In Situ or Added as Bioingredients on Yogurt Properties
Doleyres, Y., Schaub, L., & Lacroix, C. (2005) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(05)73100-3 · Cited by 127 · see citing works
Textural Properties of Yogurt Made with Encapsulated Nonropy Lactic Cultures
Hassan, A. N., Frank, J. F., Schmidt, K. A., et al. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76583-9 · Cited by 125 · see citing works
Streptococcus pneumoniaeCapsule Biosynthesis Protein CpsB Is a Novel Manganese-Dependent Phosphotyrosine-Protein Phosphatase
Morona, J. K., Morona, R., Miller, D. C., & Paton, J. C. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.2.577-583.2002 · Cited by 125 · see citing works
Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9
Goh, Y. J., Goin, C., O’Flaherty, S., Altermann, E., & Hutkins, R. W. (2011) · Microbial Cell Factories · doi:10.1186/1475-2859-10-s1-s22 · Cited by 123 · see citing works
Comparative analysis of the exopolysaccharide biosynthesis gene clusters from four strains of Lactobacillus rhamnosus
Péant, B., LaPointe, G., Gilbert, C., Atlan, D., Ward, P., & Roy, D. (2005) · Microbiology · doi:10.1099/mic.0.27852-0 · Cited by 122 · see citing works
Production, purification and structural study of an exopolysaccharide from Lactobacillus plantarum BC-25
Zhou, K., Zeng, Y., Yang, M., Chen, S., He, L., Ao, X., Zou, L., & Liu, S. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.02.067 · Cited by 122 · see citing works
Production of extracellular polysaccharides by Lactobacillus delbrueckii ssp. bulgaricus NCFB 2772 grown in a chemically defined medium
Grobben, G. J., Sikkema, J., Smith, M. R., & de Bont, J. A. M. (1995) · Journal of Applied Bacteriology · doi:10.1111/j.1365-2672.1995.tb03130.x · Cited by 121 · see citing works
Isolation, screening and identification of lactic acid bacteria from traditional food fermentation processes and culture collections
van den Berg, D. J. C., Smits, A., Pot, B., Ledeboer, A. M., Kersters, K., Verbake, J. M. A., & Verrips, C. T. (1993) · Food Biotechnology · doi:10.1080/08905439309549857 · Cited by 118 · see citing works
New Insights into Various Production Characteristics of Streptococcus thermophilus Strains
Cui, Y., Xu, T., Qu, X., Hu, T., Jiang, X., & Zhao, C. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17101701 · Cited by 117 · see citing works
Analysis of exopolysaccharide production by Lactobacillus casei CG11, isolated from cheese
Kojić, M., Vujčić, M. T., Banina, A., Cocconcelli, P. S., Cerning, J., & Topisirovic, L. (1992) · Applied and Environmental Microbiology · doi:10.1128/aem.58.12.4086-4088.1992 · Cited by 116 · see citing works
Genetic Analysis of Capsular Polysaccharide Synthesis Gene Clusters from All Serotypes of Streptococcus suis: Potential Mechanisms for Generation of Capsular Variation
Okura, M., Takamatsu, D., Maruyama, F., et al. (2013) · Applied and Environmental Microbiology · doi:10.1128/aem.03742-12 · Cited by 116 · see citing works
Investigation of Biofilm Forming Ability in Staphylococci Causing Bovine Mastitis Using Phenotypic and Genotypic Assays
Darwish, S., & Asfour, H. A. E. (2013) · The Scientific World JOURNAL · doi:10.1155/2013/378492 · Cited by 115 · see citing works
Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae
Eberhardt, A., Hoyland, C. N., Vollmer, D., Bisle, S., Cleverley, R. M., Johnsborg, O., Håvarstein, L. S., Lewis, R. J., & Vollmer, W. (2012) · Microbial Drug Resistance · doi:10.1089/mdr.2011.0232 · Cited by 114 · see citing works
Exopolysaccharide-producing lactic acid bacteria strains from traditional thai fermented foods: isolation, identification and exopolysaccharide characterization
Smitinont, T., Tansakul, C., Tanasupawat, S., Keeratipibul, S., Navarini, L., Bosco, M., & Cescutti, P. (1999) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(99)00094-x · Cited by 114 · see citing works
Investigation of the Relationship between Lactococcal Host Cell Wall Polysaccharide Genotype and 936 Phage Receptor Binding Protein Phylogeny
Mahony, J., Kot, W., Murphy, J., Ainsworth, S., Neve, H., Hansen, L. H., Heller, K. J., Sï¿½rensen, S. J., Hammer, K., Cambillau, C., et al. (2013) · Applied and Environmental Microbiology · doi:10.1128/aem.00653-13 · Cited by 114 · see citing works
Functional Analysis of Glycosyltransferase Genes from Lactococcus lactis and Other Gram-Positive Cocci: Complementation, Expression, and Diversity
van Kranenburg, R., Vos, H. R., van Swam, I. I., Kleerebezem, M., & de Vos, W. M. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.20.6347-6353.1999 · Cited by 113 · see citing works
Exopolysaccharides produced by Lactobacillus and Bifidobacterium strains abrogate in vitro the cytotoxic effect of bacterial toxins on eukaryotic cells
Ruas‐Madiedo, P., Medrano, M., Salazar, N., Reyes‐Gavilán, C. G. D. L., Pérez, P. F., & Abraham, A. G. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2010.04839.x · Cited by 110 · see citing works
Effect of Exopolysaccharides on Phage-Host Interactions in Lactococcus lactis
Deveau, H., Calsteren, M. V., & Moineau, S. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.9.4364-4369.2002 · Cited by 109 · see citing works
Genetics and engineering of microbial exopolysaccharides for food: approaches for the production of existing and novel polysaccharides
van Kranenburg, R., Boels, I. C., Kleerebezem, M., & de Vos, W. M. (1999) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(99)00017-8 · Cited by 107 · see citing works
Staphylococcus aureus Mutants Lacking the LytR-CpsA-Psr Family of Enzymes Release Cell Wall Teichoic Acids into the Extracellular Medium
Chan, Y. G. Y., Frankel, M. B., Haunreiter, V. D., Schneewind, O., & Missiakas, D. M. (2013) · Journal of Bacteriology · doi:10.1128/jb.00544-13 · Cited by 106 · see citing works
Analysis of the exopolysaccharides produced by Lactobacillus delbrueckii subsp. bulgaricus NCFB 2772 grown in continuous culture on glucose and fructose
Grobben, G. J., van Casteren, W. H. M., Schols, H. A., Oosterveld, A., Sala, G., Smith, M. R., Sikkema, J., & de Bont, J. A. M. (1997) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051089 · Cited by 103 · see citing works
Capsular and slime-polysaccharide production by Lactobacillus rhamnosus JAAS8 isolated from Chinese sauerkraut: Potential application in fermented milk products
Yang, Z., Li, S., Zhang, X., Zeng, X., Li, D., Zhao, Y., & Zhang, J. (2010) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2009.12.010 · Cited by 103 · see citing works
Involvement of a Plasmid in Production of Ropiness (Mucoidness) in Milk Cultures by Streptococcus cremoris MS
Vedamuthu, E. R., & Neville, J. M. (1986) · Applied and Environmental Microbiology · doi:10.1128/aem.51.4.677-682.1986 · Cited by 102 · see citing works
The Capsular Polysaccharide of Staphylococcus aureus Is Attached to Peptidoglycan by the LytR-CpsA-Psr (LCP) Family of Enzymes
Chan, Y. G. Y., Kim, H. K., Schneewind, O., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.567669 · Cited by 102 · see citing works
Genomic insights into high exopolysaccharide-producing dairy starter bacterium Streptococcus thermophilus ASCC 1275
Wu, Q., Tun, H. M., Leung, F. C.-C., & Shah, N. P. (2014) · Scientific Reports · doi:10.1038/srep04974 · Cited by 101 · see citing works
Protein phosphorylation in bacterial signal transduction
Kobir, A., Shi, L., Bošković, A., Grangeasse, C., Franjević, D., & Mijakovic̀, I. (2011) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.01.006 · Cited by 101 · see citing works
Sequence-structure relationships in polysaccharide co-polymerase (PCP) proteins
Morona, R., Purins, L., Tocilj, A., et al. (2008) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2008.11.001 · Cited by 100 · see citing works
Improvement of Texture and Structure of Reduced-Fat Cheddar Cheese by Exopolysaccharide-Producing Lactococci
Dabour, N., Kheadr, E., Benhamou, N., Fliss, I., & LaPointe, G. (2006) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(06)72073-2 · Cited by 100 · see citing works
Lactobacillus-produced exopolysaccharides and their potential health benefits: A review
Patten, D. A., & Laws, A. P. (2015) · Beneficial Microbes · doi:10.3920/bm2014.0117 · Cited by 100 · see citing works
An alternative method for screening lactic acid bacteria for the production of exopolysaccharides with rapid confirmation
Paulo, E. M., Vasconcelos, M. P., Oliveira, I. S., Affe, H. M. D. J., Nascimento, R., de Melo, I. S., Roque, M. R. D. A., & de Assis, S. A. (2012) · Food Science and Technology · doi:10.1590/s0101-20612012005000094 · Cited by 100 · see citing works
Capsular Polysaccharide Expression in Commensal Streptococcus Species: Genetic and Antigenic Similarities to Streptococcus pneumoniae
Skov Sørensen, U. B., Yao, K., Yang, Y., Tettelin, H., & Kilian, M. (2016) · mBio · doi:10.1128/mbio.01844-16 · Cited by 100 · see citing works
Introduction of the exopolysaccharide gene cluster from Streptococcus thermophilus Sfi6 into Lactococcus lactis MG1363: production and characterization of an altered polysaccharide
Stingele, F., Vincent, S. J. F., Faber, E. J., Newell, J. W., Kamerling, J. P., & Neeser, J. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01441.x · Cited by 99 · see citing works
RELATION BETWEEN SENSORY TEXTURE PROPERTIES AND EXOPOLYSACCHARIDE DISTRIBUTION IN SET AND IN STIRRED YOGHURTS PRODUCED WITH DIFFERENT STARTER CULTURES
Folkenberg, D. M., Dejmek, P., Skriver, A., & Ipsen, R. (2005) · Journal of Texture Studies · doi:10.1111/j.1745-4603.2005.00010.x · Cited by 98 · see citing works
Rheological Properties of Yogurt Made with Encapsulated Nonropy Lactic Cultures
Hassan, A. N., Frank, J. F., Schmidt, K. A., & Shalabi, S. I. (1996) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(96)76582-7 · Cited by 97 · see citing works
Advances in Production and Simplified Methods for Recovery and Quantification of Exopolysaccharides for Applications in Food and Health
Leroy, F., & De Vuyst, L. (2016) · Journal of Dairy Science · doi:10.3168/jds.2015-9936 · Cited by 96 · see citing works
Control of EpsE, the Phosphoglycosyltransferase Initiating Exopolysaccharide Synthesis in Streptococcus thermophilus , by EpsD Tyrosine Kinase
Minić, Z., Marie, C., Delorme, C., Faurie, J., Mercier, G., Ehrlich, S. D., & Renault, P. (2007) · Journal of Bacteriology · doi:10.1128/jb.01122-06 · Cited by 95 · see citing works
Characterization of the individual glucose uptake systems of Lactococcus lactis: mannose‐PTS, cellobiose‐PTS and the novel GlcU permease
Castro, R., Neves, A. R., Fonseca, L. L., Pool, W. A., Kok, J., Kuipers, O. P., & Santos, H. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06564.x · Cited by 93 · see citing works
Self-citation
Genetic and biochemical characterization of exopolysaccharide biosynthesis by Lactobacillus delbrueckii subsp. bulgaricus
Lamothe, G. T., Jolly, L., Mollet, B., & Stingele, F. (2002) · Archives of Microbiology · doi:10.1007/s00203-002-0447-x · Cited by 92 · see citing works
Enhancement of Exopolysaccharide Production by Lactobacillus delbrueckii subsp. bulgaricus NCFB 2772 with a Simplified Defined Medium
Grobben, G. J., Chin‐Joe, I., Kitzen, V. A., Boels, I. C., Boer, F., Sikkema, J., Smith, M. R., & de Bont, J. A. M. (1998) · Applied and Environmental Microbiology · doi:10.1128/aem.64.4.1333-1337.1998 · Cited by 92 · see citing works
The role of exopolysaccharide produced by Lactococcus lactis subsp. cremoris in structure formation and recovery of acid milk gels
Kristo, E., Miao, Z., & Corredig, M. (2011) · International Dairy Journal · doi:10.1016/j.idairyj.2011.02.002 · Cited by 91 · see citing works
Physiological approach to extracellular polysaccharide production by Lactobacillus rhamnosus strain C83
Gamar, L., Blondeau, K., & Simonet, J.-M. (1997) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.1997.00228.x · Cited by 89 · see citing works
Requirement for Phosphoglucomutase in Exopolysaccharide Biosynthesis in Glucose- and Lactose-Utilizing Streptococcus thermophilus
Levander, F., & Rådström, P. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.6.2734-2738.2001 · Cited by 89 · see citing works
Self-regulation of exopolysaccharide production in Bacillus subtilis by a tyrosine kinasePreprint
Elsholz, A. K. W., Wacker, S., & Losick, R. M. (2014) · Genes & Development · doi:10.1101/gad.246397.114 · Cited by 88 · see citing works
Direct Observation of Bacterial Exopolysaccharides in Dairy Products Using Confocal Scanning Laser Microscopy
Hassan, A. N., Frank, J. F., & Qvist, K. B. (2002) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(02)74243-4 · Cited by 88 · see citing works
Exopolysaccharide Biosynthesis in Lactococcus lactis NIZO B40: Functional Analysis of the Glycosyltransferase Genes Involved in Synthesis of the Polysaccharide Backbone
van Kranenburg, R., van Swam, I. I., Marugg, J. D., Kleerebezem, M., & de Vos, W. M. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.1.338-340.1999 · Cited by 86 · see citing works
Phylogenetic distribution and membrane topology of the LytR-CpsA-Psr protein family
Hübscher, J., Lüthy, L., Berger‐Bächi, B., & Meier, P. S. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-617 · Cited by 86 · see citing works
Depletion interaction of casein micelles and an exocellular polysaccharide
Tuinier, R., ten Grotenhuis, E., Holt, C., et al. (1999) · Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics · doi:10.1103/physreve.60.848 · Cited by 86 · see citing works
CpsE from Type 2Streptococcus pneumoniaeCatalyzes the Reversible Addition of Glucose-1-Phosphate to a Polyprenyl Phosphate Acceptor, Initiating Type 2 Capsule Repeat Unit Formation
Cartee, R. T., Forsee, W. T., Bender, M. H., et al. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.21.7425-7433.2005 · Cited by 86 · see citing works
Gel formation and rheological properties of fermented milk with in situ exopolysaccharide production by lactic acid bacteria
Gentès, M., St‐Gelais, D., & Turgeon, S. L. (2011) · Dairy Science and Technology · doi:10.1007/s13594-011-0039-0 · Cited by 84 · see citing works
Biofilm formation in Streptococcus pneumoniae
Domenech, M., Garcı́a, E., & Moscoso, M. (2011) · Microbial Biotechnology · doi:10.1111/j.1751-7915.2011.00294.x · Cited by 83 · see citing works
Use of exopolysaccharide-producing cultures to improve the functionality of low fat cheese
Broadbent, J. R., McMahon, D. J., Oberg, C. J., & Welker, D. L. (2001) · International Dairy Journal · doi:10.1016/s0958-6946(01)00084-x · Cited by 83 · see citing works
Exopolysaccharide-Producing Bacteria from Sugar Beets
Tallgren, A. H., Airaksinen, U., von Weissenberg, R., et al. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.2.862-864.1999 · Cited by 81 · see citing works
Fast carbohydrate analysis via liquid chromatography coupled with ultra violet and electrospray ionization ion trap detection in 96-well format
Rühmann, B., Schmid, J., & Sieber, V. (2014) · Journal of Chromatography A · doi:10.1016/j.chroma.2014.05.014 · Cited by 79 · see citing works
Influence of different substrate limitations on the yield, composition and molecular mass of exopolysaccharides produced by Lactococcus lactis subsp. cremoris in continuous cultures
Looijesteijn, P. J., van Casteren, W. H. M., Tuinier, R., Doeswijk‐Voragen, C. H. L., & Hugenholtz, J. (2000) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2000.01082.x · Cited by 77 · see citing works
Lactobacillus crispatus L1: high cell density cultivation and exopolysaccharide structure characterization to highlight potentially beneficial effects against vaginal pathogens
Donnarumma, G., Molinaro, A., Cimini, D., De Castro, C., Valli, V., De Gregorio, V., De Rosa, M., & Schiraldi, C. (2014) · BMC Microbiology · doi:10.1186/1471-2180-14-137 · Cited by 76 · see citing works
Comparison of the thickening properties of fourLactobacillus delbrueckiisubsp.bulgaricusstrains and physicochemical characterization of their exopolysaccharides
Pétry, S., Furlan, S., Waghorne, W. E., Saulnier, L., Cerningâ, J., & Maguin, E. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00214-3 · Cited by 76 · see citing works
Functional Analysis of Glycosyltransferases Encoded by the Capsular Polysaccharide Biosynthesis Locus of Streptococcus pneumoniae Serotype 14
Kolkman, M. A. B., van der Zeijst, B. A. M., & Nuijten, P. J. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.31.19502 · Cited by 75 · see citing works
Exopolysaccharide (EPS) Synthesis by Oenococcus oeni: From Genes to Phenotypes
Dimopoulou, M., Vuillemin, M., Campbell-Sills, H., Lucas, P., Ballestra, P., Miot‐Sertier, C., Favier, M., Coulon, J., Moine, V., Doco, T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098898 · Cited by 75 · see citing works
Interactions Between Milk Proteins and Exopolysaccharides Produced by Lactococcus lactis Observed by Scanning Electron Microscopy
Hernandez, I. A., Goff, H. D., & Corredig, M. (2008) · Journal of Dairy Science · doi:10.3168/jds.2007-0876 · Cited by 73 · see citing works
Characterization of a novel polysaccharide with anti-colon cancer activity from Lactobacillus helveticus MB2-1
Li, W., Tang, W., Ji, J., Xia, X., Rui, X., Chen, X., Jiang, M., Zhou, J., & Dong, M. (2015) · Carbohydrate Research · doi:10.1016/j.carres.2014.12.014 · Cited by 72 · see citing works
Gelation and resistance to shearing of fermented milk: Role of exopolysaccharides
Girard, M., & Schaffer-Lequart, C. (2006) · International Dairy Journal · doi:10.1016/j.idairyj.2006.08.007 · Cited by 72 · see citing works
Spontaneous Mutation Reveals Influence of Exopolysaccharide on Lactobacillus johnsonii Surface Characteristics
Horn, N., Wegmann, U., Dertli̇, E., Mulholland, F., Collins, S. R. A., Waldron, K. W., Bongaerts, R. J., Mayer, M. J., & Narbad, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059957 · Cited by 72 · see citing works
Autophosphorylation of the Bacterial Tyrosine-Kinase CpsD Connects Capsule Synthesis with the Cell Cycle in Streptococcus pneumoniae
Nourikyan, J., Kjos, M., Mercy, C., Cluzel, C., Morlot, C., Noirot‐Gros, M., Guiral, S., Lavergne, J.-P., Veening, J., & Grangeasse, C. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005518 · Cited by 72 · see citing works
Exopolysaccharides of Lactic Acid Bacteria for Food and Colon Health Applications
TSUDA, H. (2013) · InTech eBooks · doi:10.5772/50839 · Cited by 71 · see citing works
Effect of galactose and glucose on the exopolysaccharide production and the activities of biosynthetic enzymes in Lactobacillus casei CRL 87
Mozzi, F., Rollán, G., de Giori, G. S., & de Valdez, G. F. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01367.x · Cited by 70 · see citing works
Identification and Molecular Characterization of the Chromosomal Exopolysaccharide Biosynthesis Gene Cluster from Lactococcus lactis subsp. cremoris SMQ-461
Dabour, N., & LaPointe, G. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.11.7414-7425.2005 · Cited by 69 · see citing works
The Influence of Fermentation Condition on Production and Molecular Mass of EPS Produced by Streptococcus thermophilus 05-34 in Milk-Based Medium
Li, D., Li, J., Zhao, F., Wang, G., Qin, Q., & Hao, Y. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2015.10.129 · Cited by 69 · see citing works
Structural characterization of the exopolysaccharide produced by Lactobacillus acidophilus LMG9433
Robijn, G. W., Gallego, R. G., van den Berg, D. J. C., Haas, H., Kamerling, J. P., & Vliegenthart, J. F. G. (1996) · Carbohydrate Research · doi:10.1016/s0008-6215(96)90799-5 · Cited by 68 · see citing works
Gelation of skim milk containing anionic exopolysaccharides and recovery of texture after shearing
Girard, M., & Schaffer-Lequart, C. (2006) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2006.07.012 · Cited by 65 · see citing works
Staphylococcus aureus Operates Protein-tyrosine Phosphorylation through a Specific Mechanism
Soulat, D., Jault, J., Duclos, B., et al. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m513600200 · Cited by 65 · see citing works
Carbon and Energy Storage in Bacteria
WILKINSON, J. F. (1963) · Journal of General Microbiology · doi:10.1099/00221287-32-2-171 · Cited by 65 · see citing works
Structural and immunochemical studies of neutral exopolysaccharide produced by Lactobacillus johnsonii 142
Górska, S., Jachymek, W., Rybka, J., Strus, M., Heczko, P. B., & Gamian, A. (2009) · Carbohydrate Research · doi:10.1016/j.carres.2009.09.015 · Cited by 64 · see citing works
Streptococcus agalactiae Capsule Polymer Length and Attachment Is Determined by the Proteins CpsABCD
Toniolo, C., Balducci, E., Romano, M. R., Proietti, D., Ferlenghi, I., Grandi, G., Berti, F., Ros, I. M. Y., & Janulczyk, R. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.631499 · Cited by 63 · see citing works
UDP-galactose 4-epimerase: a key enzyme in exopolysaccharide formation by Lactobacillus casei CRL 87 in controlled pH batch cultures
Mozzi, F., de Giori, G. S., & de Valdez, G. F. (2003) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2003.01821.x · Cited by 62 · see citing works
Interactions between EPS-producing Streptococcus thermophilus strains in mixed yoghurt cultures
Folkenberg, D. M., Dejmek, P., Skriver, A., & Ipsen, R. (2006) · Journal of Dairy Research · doi:10.1017/s0022029906001920 · Cited by 62 · see citing works
Physico-chemical characterization of an exopolysaccharide produced by a non-ropy strain of Leuconostoc sp. CFR 2181 isolated from dahi, an Indian traditional lactic fermented milk product
Vijayendra, S. V. N., Palanivel, G., Mahadevamma, S., & Tharanathan, R. N. (2007) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2007.08.016 · Cited by 61 · see citing works
Structural characterisation of the exopolysaccharide produced by Streptococcus thermophilus EU20
Marshall, V. M., Dunn, H., Elvin, M., McLay, N. R., Gu, Y., & Laws, A. P. (2001) · Carbohydrate Research · doi:10.1016/s0008-6215(01)00052-0 · Cited by 61 · see citing works
Phage-Host Interactions of Cheese-Making Lactic Acid Bacteria
Mahony, J., McDonnell, B., Casey, E., & van Sinderen, D. (2016) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-041715-033322 · Cited by 60 · see citing works
Deletion of hypothetical wall teichoic acid ligases in Staphylococcus aureus activates the cell wall stress response
Haunreiter, V. D., Meier, P. S., Heusser, R., Kupferschmied, P., Fazekas, J., Friebe, S., Staufer, S. B., Majcherczyk, P. A., Moreillon, P., Berger‐Bächi, B., et al. (2012) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2012.02603.x · Cited by 60 · see citing works
Increased Exopolysaccharide Production in Lactococcus lactis due to Increased Levels of Expression of the NIZO B40 eps Gene Cluster
Boels, I. C., van Kranenburg, R., Kanning, M. W., Chong, B. F., de Vos, W. M., & Kleerebezem, M. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.8.5029-5031.2003 · Cited by 60 · see citing works
Interactions of the cell-wall glycopolymers of lactic acid bacteria with their bacteriophages
Chapot, M.-P. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00236 · Cited by 60 · see citing works
Rewiring the Pneumococcal Cell Cycle with Serine/Threonine- and Tyrosine-kinases
Grangeasse, C. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.04.004 · Cited by 60 · see citing works
Fat-free yogurt made using a galactose-positive exopolysaccharide-producing recombinant strain of Streptococcus thermophilus
Robitaille, G., Tremblay, A., Moineau, S., St‐Gelais, D., Vadeboncoeur, C., & Britten, M. (2009) · Journal of Dairy Science · doi:10.3168/jds.2008-1312 · Cited by 59 · see citing works
Structural studies of the exopolysaccharide from Lactobacillus plantarum C88 using NMR spectroscopy and the program CASPER
Fontana, C., Li, S., Yang, Z., & Widmalm, G. (2014) · Carbohydrate Research · doi:10.1016/j.carres.2014.09.003 · Cited by 59 · see citing works
Nucleotide Sequence Analysis of the Lactococcal EPS Plasmid pNZ4000
van Kranenburg, R., Kleerebezem, M., & de Vos, W. M. (2000) · Plasmid · doi:10.1006/plas.1999.1453 · Cited by 59 · see citing works
Screening of lactic acid bacteria from Indonesia reveals glucansucrase and fructansucrase genes in two differentWeissella confusastrains from soya
Malik, A., Radji, M., Kralj, S., & Dijkhuizen, L. (2009) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2009.01772.x · Cited by 59 · see citing works
High throughput exopolysaccharide screening platform: From strain cultivation to monosaccharide composition and carbohydrate fingerprinting in one day
Rühmann, B., Schmid, J., & Sieber, V. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2014.12.021 · Cited by 58 · see citing works
Functional Analysis of the CpsA Protein of Streptococcus agalactiae
Hanson, B. R., Runft, D. L., Streeter, C. C., Kumar, A., Carion, T. W., & Neely, M. N. (2012) · Journal of Bacteriology · doi:10.1128/jb.06373-11 · Cited by 58 · see citing works
Construction of Streptococcus lactis subsp. lactis Strains with a Single Plasmid Associated with Mucoid Phenotype
von Wright, A., & Tynkkynen, S. (1987) · Applied and Environmental Microbiology · doi:10.1128/aem.53.6.1385-1386.1987 · Cited by 57 · see citing works
Exopolysaccharide production by Lactobacillus delbruckii subsp. bulgaricus and Streptococcus thermophilus strains under different growth conditions
Aslım, B., Yüksekdağ, Z. N., Beyatlı, Y., & Mercan, N. (2005) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-004-3613-2 · Cited by 57 · see citing works
The complete cps gene cluster from Streptococcus thermophilus NCFB 2393 involved in the biosynthesis of a new exopolysaccharide
Almiron‐Roig, E., Mulholland, F., Gasson, M. J., et al. (2000) · Microbiology · doi:10.1099/00221287-146-11-2793 · Cited by 57 · see citing works
Heterologous expression and characterization of the exopolysaccharide from Streptococcus thermophilus Sfi39
Germond, J., Delley, M., D'Amico, N., & Vincent, S. J. F. (2001) · European Journal of Biochemistry · doi:10.1046/j.0014-2956.2001.02450.x · Cited by 56 · see citing works
Characterization of lactic acid bacteria isolated from sourdoughs for Cornetto, a traditional bread produced in Basilicata (Southern Italy)
Zotta, T., Piraino, P., Parente, E., Salzano, G., & Ricciardi, A. (2008) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-008-9671-0 · Cited by 55 · see citing works
Identification and Functional Characterization of the Lactococcus lactis rfb Operon, Required for dTDP-Rhamnose Biosynthesis
Boels, I. C., Beerthuyzen, M. M., Kosters, M. H. W., van Kaauwen, M., Kleerebezem, M., & de Vos, W. M. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.5.1239-1248.2004 · Cited by 55 · see citing works
Exopolysaccharides produced by Oenococcus oeni: From genomic and phenotypic analysis to technological valorization
Dimopoulou, M., Bardeau, T., Ramonet, P.-Y., Miot‐Sertier, C., Claisse, O., Doco, T., Petrel, M., Lucas, P., & Dols‐Lafargue, M. (2015) · Food Microbiology · doi:10.1016/j.fm.2015.07.011 · Cited by 55 · see citing works
A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence
Schaffner, T. O., Hinds, J., Gould, K. A., et al. (2014) · BMC Microbiology · doi:10.1186/s12866-014-0210-x · Cited by 54 · see citing works
Plasmid-encoded functions of ropy lactic acid streptococcal strains from Scandinavian fermented milk
Neve, H., Geis, A., & Teuber, M. (1988) · Biochimie · doi:10.1016/0300-9084(88)90218-0 · Cited by 54 · see citing works
Characterization of Multiple Regions Involved in Replication and Mobilization of Plasmid pNZ4000 Coding for Exopolysaccharide Production in Lactococcus lactis
van Kranenburg, R., & de Vos, W. M. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.20.5285-5290.1998 · Cited by 53 · see citing works
Enzymes involved in carbohydrate metabolism and their role on exopolysaccharide production in Streptococcus thermophilus
Escalante, A., Wacher, C., García-Garibay, & Farrés, A. (1998) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.1997.00330.x · Cited by 53 · see citing works
Synthesis of capsular polysaccharide at the division septum of Streptococcus pneumoniae is dependent on a bacterial tyrosine kinase
Henriques, M. X., Rodrigues, T., Carido, M., et al. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07828.x · Cited by 53 · see citing works
Exopolysaccharide production during batch cultures with free and immobilized Lactobacillus rhamnosus RW-9595M
Bergmaier, D., Champagne, C. P., & Lacroix, C. (2003) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2003.02084.x · Cited by 52 · see citing works
Structural analysis of the exopolysaccharide produced by Streptococcus thermophilus ST1 solely by NMR spectroscopy
Säwén, E., Huttunen, E., Zhang, X., Yang, Z., & Widmalm, G. (2010) · Journal of Biomolecular NMR · doi:10.1007/s10858-010-9413-0 · Cited by 52 · see citing works
Exopolysaccharide Production and Ropy Phenotype Are Determined by Two Gene Clusters in Putative Probiotic Strain Lactobacillus paraplantarum BGCG11
Živković, M., Miljković, M., Ruas‐Madiedo, P., Strahinić, I., Tolinački, M., Golić, N., & Kojić, M. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.03028-14 · Cited by 52 · see citing works
Structural studies of the rhamnose-rich cell wall polysaccharide of Lactobacillus casei BL23
VINOGRADOV, E. V., Sadovskaya, I., Grard, T., & Chapot, M.-P. (2016) · Carbohydrate Research · doi:10.1016/j.carres.2016.10.002 · Cited by 52 · see citing works
Impact of LytR-CpsA-Psr Proteins on Cell Wall Biosynthesis in Corynebacterium glutamicum
Baumgart, M., Schubert, K., Bramkamp, M., & Frunzke, J. (2016) · Journal of Bacteriology · doi:10.1128/jb.00406-16 · Cited by 51 · see citing works
The structure and immunomodulatory activity on intestinal epithelial cells of the EPSs isolated from Lactobacillus helveticus sp. Rosyjski and Lactobacillus acidophilus sp. 5e2
Patten, D. A., Leivers, S., Chadha, M. J., Maqsood, M., Humphreys, P. N., Laws, A. P., & Collett, A. (2013) · Carbohydrate Research · doi:10.1016/j.carres.2013.12.008 · Cited by 50 · see citing works
Effect of protein supplementation on the rheological characteristics of milk permeates fermented with exopolysaccharide-producing Lactococcus lactis subsp. cremoris
Hernandez, I. A., Hassan, A. N., Goff, H. D., & Corredig, M. (2008) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2008.11.004 · Cited by 50 · see citing works
The role of exopolysaccharide-producing cultures and whey protein ingredients in yoghurt
Buldo, P., Benfeldt, C., Folkenberg, D. M., et al. (2016) · LWT · doi:10.1016/j.lwt.2016.04.050 · Cited by 50 · see citing works
Self-citation
Exopolysaccharide production by three different strains of S treptococcus thermophilus and its effect on physical properties of acidified milk
Mende, S., Mentner, C., Thomas, S., Rohm, H., & Jaros, D. (2012) · Engineering in Life Sciences · doi:10.1002/elsc.201100114 · Cited by 48 · see citing works
Exopolysaccharide–milk protein interactions in a dairy model system simulating yoghurt conditions
Gentès, M., St‐Gelais, D., & Turgeon, S. L. (2013) · Dairy Science and Technology · doi:10.1007/s13594-013-0121-x · Cited by 47 · see citing works
Rheological, sensorial, and chemopreventive properties of milk fermented with exopolysaccharide-producing lactic cultures
Purohit, D. H., Hassan, A. N., Bhatia, E., Zhang, X., & Dwivedi, C. (2009) · Journal of Dairy Science · doi:10.3168/jds.2008-1256 · Cited by 47 · see citing works
Intracellular phosphorylation of glucose analogs via the phosphoenolpyruvate: mannose-phosphotransferase system in Streptococcus lactis
Thompson, J., & Chassy, B. M. (1985) · Journal of Bacteriology · doi:10.1128/jb.162.1.224-234.1985 · Cited by 46 · see citing works

Flagged first, then by citations

Research works printed but not linked: 8

Aanensen DM, Mavroidi A, Bentley SD et al. Predicted func- tions and linkage specificities of the products of the Strep- tococcus pneumoniae capsular biosynthetic loci. J Bacteriol 2007;189:7856-76.
Dertli E, Mayer MJ, Colquhoun IJ et al. EpsA is an essential gene in exopolysaccharide production in Lactobacillus john- sonii FI9785. Microb Biotechnol 2016;9:496-501.
Krajl S, Van Geel-Schutten GH, Van Der Maarel MJEC et al. Ef- ficient screening methods for glucosyltransferase genes in Lactobacillus strains. Biocatal Biotransform 2003;21:181-7.
Mende S, Dong T, Rathemacher A et al. Physicochemical char- acterisation of the exopolysaccharides of Streptococcus ther- mophilus ST-143. Int J Food Sci Technol 2014;49:1254-63.
Mozzi F, Torino MI, de Valdez GF. Identification of exopolysaccharide-producing lactic acid bacteria. In: Spencer JFT, de Ragout Spencer AL (eds.) Food Microbiol- ogy Protocols. Totowa: Humana Press, 2001, 183-90.
Petry S, Furlan S, Waghorne E et al. Comparison of the thicken- ing properties of four Lactobacillus delbrueckii subsp. bulgari- cus strains and physicochemical characterization of their ex- opolysaccharides. FEMS Microbiol Lett 2003;221:285-91.
Tuinier R, van Casteren WH, Looijesteijn PJ et al. Effects of structural modifications on some physical characteristics of exopolysaccharides from Lactococcus lactis. Biopolymers 2001;59:160-6.
Ullrich M (ed.) Bacterial Polysaccharides: Current Innovations and Fu- ture Trends. Poole: Horizon Scientific Press, 2009.

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Authors: Zeidan, A. A., Poulsen, V. K., Janzen, T., Buldo, P., Derkx, P. M. F., Øregaard, G., & Neves, A. R.
Affiliations: Chr. Hansen (Denmark) (DK)
Corresponding author: Zeidan, Ahmad A.
Poulsen, Vera Kuzina
Neves, Ana Rute
ORCID: Zeidan, Ahmad A.
Poulsen, Vera Kuzina
Buldo, Patrizia
Derkx, Patrick M. F.
Neves, Ana Rute
Venue: FEMS Microbiology Reviews
Publisher: Oxford University Press (OUP)
Published: 2017-06-19
Volume: 41
Issue: Supp_1
Pages: S168-S200
ISSN: 0168-6445 (ISSN-L)
1574-6976
DOI: 10.1093/femsre/fux017
OpenAlex: W2630895790
Cited by: 326
References: 259
Citations by year: 2026: 47 · 2025: 39 · 2024: 28 · 2023: 39 · 2022: 39 · 2021: 40 · 2020: 41 · 2019: 27 · 2018: 23 · 2017: 1 · 2015: 1
FWCI: 2.71
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: FEMS Microbiology Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biopolymer Synthesis and Applications
Keywords: lactic acid bacteria, polysaccharide production, exopolysaccharides, capsular polysaccharide, polysaccharide synthesis, structure-function relationship, high-throughput screening
MeSH terms: Carrier Proteins, Fermentation, Food Microbiology, Phosphorylases, Industrial Microbiology, Polysaccharides, Bacterial, Bacterial Capsules, Biosynthetic Pathways, Lactobacillales

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Polysaccharide Production by Lactic Acid Bacteria: From Genes to Industrial Applications

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