The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Is the Optimal Level of Protein Intake for Older Adults Greater Than the Recommended Dietary Allowance?
Open accessAbstract
BACKGROUND: Protein is a macronutrient essential for growth, muscle function, immunity and overall tissue homeostasis. Suboptimal protein intake can significantly impact physical function and overall health in older adults. METHODS: This article reviews the literature on the recommendations for protein intake in older adults in light of the new evidence linking protein intake with sarcopenia and physical function. Challenges and opportunities for optimal protein nutrition in older persons are discussed. RESULTS: Recent metabolic and epidemiological studies suggest that the current recommendations of protein intake may not be adequate for maintenance of physical function and optimal health in older adults. Methodological limitations and novel concepts in protein nutrition are also discussed. CONCLUSION: We conclude that new research and novel research methodologies are necessary to establish the protein needs and optimal patterns of protein intake for older persons.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gait speed and survival in older adults.
Studenski, S. (2011) · JAMA · doi:10.1001/jama.2010.1923 · Cited by 4,558
Fielding, R. A., Vellas, B., Evans, W. J., Bhasin, S., Morley, J. E., Newman, A. B., Abellan van Kan, G., Andrieu, S., Bauer, J., Breuille, D., et al. (2011) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2011.01.003 · Cited by 3,256
Self-citationAnabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
Cuthbertson, D., Smith, K., Babraj, J., Leese, G., Waddell, T., Atherton, P., Wackerhage, H., Taylor, P. M., & Rennie, M. J. (2005) · The FASEB Journal · doi:10.1096/fj.04-2640fje · Cited by 1,211
Weight loss, exercise, or both and physical function in obese older adults
Villareal, D. T., Chode, S., Parimi, N., Sinacore, D. R., Hilton, T., Armamento-Villareal, R., Napoli, N., Qualls, C., & Shah, K. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1008234 · Cited by 1,096
Katsanos, C. S., Kobayashi, H., Sheffield-Moore, M., Aarsland, A., & Wolfe, R. R. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00488.2005 · Cited by 923
Self-citationVolpi, E., Kobayashi, H., Sheffield-Moore, M., Mittendorfer, B., & Wolfe, R. R. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.2.250 · Cited by 846
Self-citationFarnsworth, E., Luscombe, N. D., Noakes, M., Wittert, G., Argyiou, E., & Clifton, P. M. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.1.31 · Cited by 438 · cited 1×
“Additionally, hypocaloric diets for sarcopenic obesity in older persons should supply adequate protein, which may help prevent muscle loss (44) and improve adherence to low energy intake (45).”
BackgroundFulgoni, V. L. (2008) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/87.5.1554s · Cited by 369 · cited 7×
“However, older adults (especially women) may consume protein intakes within the AMDR, yet below the EAR (1).”
BackgroundInfluentialNutrient signalling in the regulation of human muscle protein synthesis
Fujita, S., Dreyer, H. C., Drummond, M. J., Glynn, E. L., Cadenas, J. G., Yoshizawa, F., Volpi, E., & Rasmussen, B. B. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.134593 · Cited by 339
Self-citationProtein Intake and Incident Frailty in the Women's Health Initiative Observational Study
Beasley, J. M., LaCroix, A. Z., Neuhouser, M. L., Huang, Y., Tinker, L., Woods, N., Michael, Y., Curb, J. D., & Prentice, R. L. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02866.x · Cited by 337
Ferrando, A. A., Paddon-Jones, D., Hays, N. P., Kortebein, P., Ronsen, O., Williams, R. H., McComb, A., Symons, T. B., Wolfe, R. R., & Evans, W. (2010) · Clinical Nutrition · doi:10.1016/j.clnu.2009.03.009 · Cited by 237 · cited 1×
“However, excess amino acids during inactivity can help maintain muscle mass in older adults (49).”
BackgroundSelf-citationProtein intake and muscle strength in older persons: does inflammation matter?
Bartali, B., Frongillo, E. A., Stipanuk, M. H., Bandinelli, S., Salvini, S., Palli, D., Morais, J. A., Volpato, S., Guralnik, J. M., & Ferrucci, L. (2012) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2011.03833.x · Cited by 76
Protein and amino acid requirements in the elderly
Kurpad, A., & Vaz, M. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601035 · Cited by 70
Benton, M. J., Wagner, C. L., & Alexander, J. L. (2010) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0b013e3181d6f94f · Cited by 29
Cited by
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., et al. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.021 · Cited by 2,553
Self-citationDeutz, N. E. P., Bauer, J. M., Barazzoni, R., Biolo, G., Boirie, Y., Bosy-Westphal, A., Cederholm, T., Cruz-Jentoft, A., Krznariç, Z., Nair, K. S., et al. (2014) · Clinical Nutrition · doi:10.1016/j.clnu.2014.04.007 · Cited by 1,738
Moore, D. R., Churchward-Venne, T. A., Witard, O., Breen, L., Burd, N. A., Tipton, K. D., & Phillips, S. M. (2015) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glu103 · Cited by 770
Dietary protein intake and human health
Wu, G. (2016) · Food & Function · doi:10.1039/c5fo01530h · Cited by 748
Nutrition, frailty, and sarcopenia
Cruz-Jentoft, A. J., Kiesswetter, E., Drey, M., & Sieber, C. C. (2017) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0709-0 · Cited by 488
Metadata
- Authors
- Volpi, E., Campbell, W. W., Dwyer, J. T., Johnson, M. A., Jensen, G. L., Morley, J. E., & Wolfe, R. R.
- Venue
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-11-26
- Volume
- 68
- Issue
- 6
- Pages
- 677-681
- ISSN
- 1079-5006 (ISSN-L)
- 1758-535X
- OpenAlex
- W2129281902
- Cited by
- 381
- References
- 14
- FWCI
- 12.45
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.