Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

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Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics

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Can perfusion CT assessment of primary colorectal adenocarcinoma blood flow at staging predict for subsequent metastatic disease? A pilot study

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Hypoxia Selection of Death-resistant Cells

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Serine-dependent redox homeostasis regulates glioblastoma cell survival

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Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells

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Ovarian Carcinoma-Associated Mesenchymal Stem Cells Arise from Tissue-Specific Normal Stroma

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IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism

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Hypoxia in Breast Cancer

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Hypoxic Tumor Microenvironments Reduce Collagen I Fiber Density

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Tumor oxygenation status as a prognostic marker

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Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues

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Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen‐Dependent Photodynamic Cancer Therapy

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A turn-on fluorescent probe for tumor hypoxia imaging in living cells

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Hypoxia activates the hedgehog signaling pathway in a ligand‐independent manner by upregulation of Smo transcription in pancreatic cancer

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Mutations in the PI3K/PTEN/TSC2 Pathway Contribute to Mammalian Target of Rapamycin Activity and Increased Translation under Hypoxic Conditions

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Hypoxia and Cellular Localization Influence the Radiosensitizing Effect of Gold Nanoparticles (AuNPs) in Breast Cancer Cells

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CXCR4 as biomarker for radioresistant cancer stem cells

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Hypoxia-induced autophagy as an additional mechanism in human osteosarcoma radioresistance

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Vascular endothelial growth factor isoform expression as a determinant of blood vessel patterning in human melanoma xenografts.

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Changing the energy of an immune response.

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Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response

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Cellular Signal Transduction of the Hypoxia Response

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Mitochondria and Energetic Depression in Cell Pathophysiology

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A3 Adenosine Receptors Modulate Hypoxia-inducible Factor-1a Expression in Human A375 Melanoma Cells

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Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.

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Recent advances in pancreatic cancer: biology, treatment, and prevention

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Near-Infrared Optical Mammography for Breast Cancer Detection with Intrinsic Contrast

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Ginsenoside 20(S)-Rg3 Targets HIF-1α to Block Hypoxia-Induced Epithelial-Mesenchymal Transition in Ovarian Cancer Cells

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Hypoxia in head and neck cancer

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Residual Esophageal Cancer after Neoadjuvant Chemoradiotherapy Frequently Involves the Mucosa and Submucosa

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Is the hypoxia-inducible factor pathway important in gastric cancer?

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Treatment with siRNA and antisense oligonucleotides targeted to HIF‐1α induced apoptosis in human tongue squamous cell carcinomas

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Chlorella-gold nanorods hydrogels generating photosynthesis-derived oxygen and mild heat for the treatment of hypoxic breast cancer

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Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors

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Reduced Levels of ATF-2 Predispose Mice to Mammary Tumors

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The tumor microenvironment: An irreplaceable element of tumor budding and epithelial-mesenchymal transition-mediated cancer metastasis

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PEG‐fibrinogen hydrogels for three‐dimensional breast cancer cell culture

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MALDI-Mass Spectrometric Imaging Revealing Hypoxia-Driven Lipids and Proteins in a Breast Tumor Model

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Hypoxia can contribute to the induction of the Epstein-Barr virus (EBV) lytic cycle

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Hypoxia-induced miR-424 decreases tumor sensitivity to chemotherapy by inhibiting apoptosis

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NO and TNF-α released from activated macrophages stabilize HIF-1α in resting tubular LLC-PK1 cells

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Application of62Cu-Diacetyl-Bis (N4-Methylthiosemicarbazone) PET Imaging to Predict Highly Malignant Tumor Grades and Hypoxia-Inducible Factor-1α Expression in Patients with Glioma

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Chronic hypoxia promotes hypoxia-inducible factor-1α–dependent resistance to etoposide and vincristine in neuroblastoma cells

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Nanomedicines Targeting the Tumor Microenvironment

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Regulatory Networks of LncRNA MALAT-1 in Cancer

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LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation

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Study of copper-cysteamine based X-ray induced photodynamic therapy and its effects on cancer cell proliferation and migration in a clinical mimic setting

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The Hidden Role of Hydrogen Sulfide Metabolism in Cancer

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Oxyhaemoglobin saturation NIR-IIb imaging for assessing cancer metabolism and predicting the response to immunotherapy

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Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole

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Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer

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Hypoxia Regulates Cross-talk between Syk and Lck Leading to Breast Cancer Progression and Angiogenesis

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The Evolving, Multifaceted Roles of Autophagy in Cancer

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Vorinostat suppresses hypoxia signaling by modulating nuclear translocation of hypoxia inducible factor 1 alpha

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Prognostic Value of Pretreatment 18F-FDG PET/CT Parameters Including Visual Evaluation in Patients With Head and Neck Squamous Cell Carcinoma

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Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells

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Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells

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Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity

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A domain responsible for HIF-1α degradation by YC-1, a novel anticancer agent

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Tumor Oxygen Dynamics: Correlation of In Vivo MRI with Histological Findings

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Diffuse Optical Monitoring of the Neoadjuvant Breast Cancer Therapy

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Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Cancer Cells to Ionizing Radiation via Inhibition of DNA Repair Machinery

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Improving cancer therapies by targeting the physical and chemical hallmarks of the tumor microenvironment

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Iridium(III) Anthraquinone Complexes as Two‐Photon Phosphorescence Probes for Mitochondria Imaging and Tracking under Hypoxia

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Increased Metastatic Dissemination in Human Melanoma Xenografts after Subcurative Radiation Treatment

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Re: Levels of Hypoxia-Inducible Factor-1 During Breast Carcinogenesis

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Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines

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The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma

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Regulation of cancer metastasis by stress pathways

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Cellular reaction to hypoxia: sensing and responding to an adverse environment

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Hypoxia Markers in Human Osteosarcoma: An Exploratory Study

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Role of carbonic anhydrase IX expression in prediction of the efficacy and outcome of primary epirubicin/tamoxifen therapy for breast cancer

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Hypoxia-Induced Signaling in the Cardiovascular System

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Non-Angiogenic Functions of VEGF in Breast Cancer

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Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity

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Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

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Synthesis and Chemical and Biological Comparison of Nitroxyl- and Nitric Oxide-Releasing Diazeniumdiolate-Based Aspirin Derivatives

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Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)

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Oxygen-independent combined photothermal/photodynamic therapy delivered by tumor acidity-responsive polymeric micelles

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Role of tumor microenvironment in cancer stem cell chemoresistance and recurrence

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Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors

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The Hypoxic Tumour Microenvironment, Patient Selection and Hypoxia-modifying Treatments

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