Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

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Hypoxia-induced TGF-β–RBFOX2–ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer

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Tyrosine Kinase p56 Regulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Tyrosine Phosphorylation of IκBα following Hypoxia/Reoxygenation

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Nano versus Molecular: Optical Imaging Approaches to Detect and Monitor Tumor Hypoxia

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Oxygen control: the often overlooked but essential piece to create better in vitro systems

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Feasibility and repeatability of PET with the hypoxia tracer [18F]HX4 in oesophageal and pancreatic cancer

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Photoacoustic lifetime imaging for direct in vivo tissue oxygen monitoring

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Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells

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The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential

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Poor prognosis in human papillomavirus–positive oropharyngeal squamous cell carcinomas that overexpress hypoxia inducible factor‐1α

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The HIF‑1α/miR‑224‑3p/ATG5 axis affects cell mobility and chemosensitivity by regulating hypoxia‑induced protective autophagy in glioblastoma and astrocytoma

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Pathological Crosstalk between Metastatic Breast Cancer Cells and the Bone Microenvironment

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Hypoxia PET Imaging with [18F]-HX4—A Promising Next-Generation Tracer

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Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas

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Involvement of Transforming Growth Factor-β1 Signaling in Hypoxia-induced Tolerance to Glucose Starvation

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Dynamic response of breast tumor oxygenation to hyperoxic respiratory challenge monitored with three oxygen-sensitive parameters

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Gold Nanoclusters-Based NIR-II Photosensitizers with Catalase-like Activity for Boosted Photodynamic Therapy

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In Vivo Optical Imaging of Tumor and Microvascular Response to Ionizing Radiation

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Oxygen Sensing, Hypoxia Tracing and in Vivo Imaging with Functional Metalloprobes for the Early Detection of Non-communicable Diseases

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Cancer cachexia demonstrates the energetic impact of gluconeogenesis in human metabolism

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Bioreductive and gene therapy approaches to hypoxic diseases

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A Versatile Theranostic Nanoemulsion for Architecture‐Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Tumors: Preclinical Validation of Parametric Images

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Transcriptional Down-Regulation of Brca1 and E-cadherin by CtBP1 in Breast Cancer

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Hypoxia‐induced SM22α in A549 cells activates the IGF1R/PI3K/Akt pathway, conferring cellular resistance against chemo‐ and radiation therapy

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In vivo assessment and evaluation of lung tissue morphologic and physiological changes from non-contact endoscopic reflectance spectroscopy for improving lung cancer detection

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Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1

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Effects of acute and chronic hypoxia on the radiosensitivity of gastric and esophageal cancer cells.

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Multiparametric [18F]Fluorodeoxyglucose/ [18F]Fluoromisonidazole Positron Emission Tomography/ Magnetic Resonance Imaging of Locally Advanced Cervical Cancer for the Non-Invasive Detection of Tumor Heterogeneity: A Pilot Study

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Functional Flow Patterns and Static Blood Pooling in Tumors Revealed by Combined Contrast-Enhanced Ultrasound and Photoacoustic Imaging

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Predicting breast cancer response to neoadjuvant chemotherapy using pretreatment diffuse optical spectroscopic texture analysis

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In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy and Imaging of Tumor Microenvironment and Redox Using Functional Paramagnetic Probes

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MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models

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A one-pot synthesis of multifunctional Bi 2 S 3 nanoparticles and the construction of core–shell Bi 2 S 3 @Ce6–CeO 2 nanocomposites for NIR-triggered phototherapy

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Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas

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Advanced nanomaterials for hypoxia tumor therapy: challenges and solutions

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Peroxidase-mimicking evodiamine/indocyanine green nanoliposomes for multimodal imaging-guided theranostics for oral squamous cell carcinoma

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Targeting hypoxia and angiogenesis through HIF-1alpha inhibition

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Modulation of intratumoral hypoxia by the epidermal growth factor receptor inhibitor gefitinib detected using small animal PET imaging

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Tumor Hypoxia: Chicken, Egg, or a Piece of the Farm?

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Transdermal delivery of multifunctional CaO 2 @Mn-PDA nanoformulations by microneedles for NIR-induced synergistic therapy against skin melanoma

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Breaking‐Down Tumoral Physical Barrier by Remotely Unwrapping Metal‐Polyphenol‐Packaged Hyaluronidase for Optimizing Photothermal/Photodynamic Therapy‐Induced Immune Response

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Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer

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γ-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line

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Phase II study. Concurrent chemotherapy and radiotherapy with nitroglycerin in locally advanced non-small cell lung cancer

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MiR675-5p Acts on HIF-1α to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma

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Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients

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Hypoxia-inducible tumour-specific promoters as a dual-targeting transcriptional regulation system for cancer gene therapy

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A pH-Sensing Optode for Mapping Spatiotemporal Gradients in 3D Paper-Based Cell Cultures

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A Zero Cross-Talk Ratiometric Two-Photon Probe for Imaging of Acid pH in Living Cells and Tissues and Early Detection of Tumor in Mouse Model

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Biosynthetic energy cost for amino acids decreases in cancer evolution

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Model-based optical and acoustical compensation for photoacoustic tomography of heterogeneous mediums

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NS398 reduces hypoxia‐inducible factor (HIF)‐1α and HIF‐1 activity: Multiple‐level effects involving cyclooxygenase‐2 dependent and independent mechanisms

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Restoration of Normoxia by Ozone Therapy May Control Neoplastic Growth: A Review and a Working Hypothesis

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Correlation of radiation response with tumor oxygenation in the Dunning prostate R3327-AT1 tumor

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Lack of Microvessels in Well-Differentiated Regions of Human Head and Neck Squamous Cell Carcinoma A253 Associated with Functional Magnetic Resonance Imaging Detectable Hypoxia, Limited Drug Delivery, and Resistance to Irinotecan Therapy

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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

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Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

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12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells

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MiRNA-486 regulates angiogenic activity and survival of mesenchymal stem cells under hypoxia through modulating Akt signal

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Oxygen Mapping of Melanoma Spheroids using Small Molecule Platinum Probe and Phosphorescence Lifetime Imaging Microscopy

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Long Noncoding RNA MALAT1 Regulates Hepatocellular Carcinoma Growth Under Hypoxia via Sponging MicroRNA-200a

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Hypoxia suppresses the production of matrix metalloproteinases and the migration of humanmonocyte‐derived dendritic cells

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Morphologic and functional renal impact of acute kidney injury after prolonged hemorrhagic shock in mice*

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Hypoxia-Inducible Factor-1 Inhibition in Combination with Temozolomide Treatment Exhibits Robust Antitumor Efficacy In vivo

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Bridging angiogenesis and immune evasion in the hypoxic tumor microenvironment

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A Mathematical Study of the Influence of Hypoxia and Acidity on the Evolutionary Dynamics of Cancer

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State of the Art in Carbon Nanomaterials for Photoacoustic Imaging

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NF-κB and TET2 promote macrophage reprogramming in hypoxia that overrides the immunosuppressive effects of the tumor microenvironment

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Cobalt chloride, a chemical inducer of hypoxia-inducible factor-1α in U251 human glioblastoma cell line

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Diffuse optical imaging and spectroscopy for cancer

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Expression of macrophage inflammatory protein‐1α and monocyte chemoattractant protein‐1 in glioma‐infiltrating microglia: Involvement of ATP and P2X7receptor

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Operable Non–Small Cell Lung Cancer: Correlation of Volumetric Helical Dynamic Contrast-enhanced CT Parameters with Immunohistochemical Markers of Tumor Hypoxia

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Differentiating the grades of thymic epithelial tumor malignancy using textural features of intratumoral heterogeneity via 18F-FDG PET/CT

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Redox Potential and ROS-Mediated Nanomedicines for Improving Cancer Therapy

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