Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

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Silencing hypoxia-inducible factor-1α inhibits cell migration and invasion under hypoxic environment in malignant gliomas

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Reconsidering azobenzene as a component of small-molecule hypoxia-mediated cancer drugs: A theranostic case study

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(Aryloxyacetylamino)benzoic Acid Analogues: A New Class of Hypoxia-Inducible Factor-1 Inhibitors

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Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling.

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Hypoxia Tolerance in Animals: Biology and Application

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Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells

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Oxygen self-sufficient photodynamic therapy

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Engineered Culture Models for Studies of Tumor-Microenvironment Interactions

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Epithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology

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Targeting Tumor Microenvironment by Small-Molecule Inhibitors

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Acute versus chronic hypoxia in tumors

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E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis

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ARK5 Is a Tumor Invasion-Associated Factor Downstream of Akt Signaling

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Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

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Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT

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Hypoxia and Hypoxia Inducible Factors in Cancer Stem Cell Maintenance

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Targeted Luminescent Near-Infrared Polymer-Nanoprobes for In Vivo Imaging of Tumor Hypoxia

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Stereotactic Ablative Radiotherapy Should Be Combined With a Hypoxic Cell Radiosensitizer

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Chemosensitization of Cancer In vitro and In vivo by Nitric Oxide Signaling

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The Presence of a Fibrotic Focus in Invasive Breast Carcinoma Correlates with the Expression of Carbonic Anhydrase IX and is a Marker of Hypoxia and Poor Prognosis

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Carbonic Anhydrase Inhibitors. Inhibition of Cytosolic Isozymes I and II and Transmembrane, Tumor-Associated Isozyme IX with Sulfamates Including EMATE Also Acting as Steroid Sulfatase Inhibitors

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In vivo quantitative imaging of tumor pH by nanosonophore assisted multispectral photoacoustic imaging

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Cell density mediated pericellular hypoxia leads to induction of HIF-1α via nitric oxide and Ras/MAP kinase mediated signaling pathways

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HIF-1-driven skeletal muscle adaptations to chronic hypoxia: molecular insights into muscle physiology

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Hypoxia Induces EMT in Low and Highly Aggressive Pancreatic Tumor Cells but Only Cells with Cancer Stem Cell Characteristics Acquire Pronounced Migratory Potential

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Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer

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MiRNA-29b suppresses tumor growth through simultaneously inhibiting angiogenesis and tumorigenesis by targeting Akt3

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Systematic investigation of mitochondrial transfer between cancer cells and T cells at single-cell resolution

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Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours

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Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function

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F-18 Fluoromisonidazole for Imaging Tumor Hypoxia: Imaging the Microenvironment for Personalized Cancer Therapy

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HIF-1alpha-mediated up-regulation of vascular endothelial growth factor, independent of basic fibroblast growth factor, is important in the switch to the angiogenic phenotype during early tumorigenesis.

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Quantifying Transient Hypoxia in Human Tumor Xenografts by Flow Cytometry

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Hypoxia-Inducible Factor 1α Expression as an Intrinsic Marker of Hypoxia

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Preliminary Study of Oxygen-Enhanced Longitudinal Relaxation in MRI: A Potential Novel Biomarker of Oxygenation Changes in Solid Tumors

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STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination

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Glucose Metabolic Dysfunction in Neurodegenerative Diseases—New Mechanistic Insights and the Potential of Hypoxia as a Prospective Therapy Targeting Metabolic Reprogramming

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Efficacy of cytotoxic agents used in the treatment of testicular germ cell tumours under normoxic and hypoxic conditions in vitro

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Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia

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Targeting tumor associated macrophages (TAMs) via nanocarriers

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Biomimetic nanoscale metal–organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy

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Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

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Pathophysiological and vascular characteristics of tumours and their importance for hyperthermia: Heterogeneity is the key issue

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Hypoxia-Inducible Factors as Essential Regulators of Inflammation

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Hypoxia Activation of Mitophagy and Its Role in Disease Pathogenesis

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Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors

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Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy

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E. coli and colorectal cancer: a complex relationship that deserves a critical mindset

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Expression of hypoxia-inducible factor 1α, hypoxia-inducible factor 2α, and von Hippel–Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1α is an independent prognostic factor in ovarian carcinoma

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AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells

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Overexpression of GLUT-1 is associated with resistance to radiotherapy and adverse prognosis in squamous cell carcinoma of the oral cavity

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Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning

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Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness

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Advances in Hypoxia-Mediated Mechanisms in Hepatocellular Carcinoma

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Hypoxia Regulates Expression and Activity of Kv1.3 Channels in T Lymphocytes: A Possible Role in T Cell Proliferation

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Hypoxia, drug therapy and toxicity

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Gene Expression Signatures as Biomarkers of Tumour Hypoxia

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Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis

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Advances in nanomaterials for treatment of hypoxic tumor

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Nitroglycerin Treatment May Enhance Chemosensitivity to Docetaxel and Carboplatin in Patients with Lung Adenocarcinoma

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