Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

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Lactate Dehydrogenase-5 (LDH-5) Expression in Human Gastric Cancer: Association with Hypoxia-Inducible Factor (HIF-1α) Pathway, Angiogenic Factors Production and Poor Prognosis

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Preconditioning of the Tumor Vasculature and Tumor Cells by Intermittent Hypoxia: Implications for Anticancer Therapies

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The Clinical Significance of Hypoxia in Human Cancers

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Oxygen, the Lead Actor in the Pathophysiologic Drama: Enactment of the Trinity of Normoxia, Hypoxia, and Hyperoxia in Disease and Therapy

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Oxygen Consumption Can Regulate the Growth of Tumors, a New Perspective on the Warburg Effect

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Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy

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Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

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Hypoxic Tumor Microenvironment and Cancer Cell Differentiation

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Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: exploiting the hypoxia-induced pathway.

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18F-EF5: A New PET Tracer for Imaging Hypoxia in Head and Neck Cancer

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The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness

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Tumor Hypoxia as a Barrier in Cancer Therapy: Why Levels Matter

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Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells

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Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells

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Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

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Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis

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Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination

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Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

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YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-κB signaling to HIF-1α accumulation during hypoxia

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Fluctuating and Diffusion-Limited Hypoxia in Hypoxia-Induced Metastasis

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Randomized Phase II Trial Comparing Nitroglycerin Plus Vinorelbine and Cisplatin With Vinorelbine and Cisplatin Alone in Previously Untreated Stage IIIB/IV Non–Small-Cell Lung Cancer

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Reactive Oxygen Species–Activatable Liposomes Regulating Hypoxic Tumor Microenvironment for Synergistic Photo/Chemodynamic Therapies

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Dominant-Negative Hypoxia-Inducible Factor-1α Reduces Tumorigenicity of Pancreatic Cancer Cells through the Suppression of Glucose Metabolism

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Increased Exposure of Phosphatidylethanolamine on the Surface of Tumor Vascular Endothelium

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Hypoxia in head and neck cancer: How much, how important?

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Hybrid TiO 2 –Ruthenium Nano‐photosensitizer Synergistically Produces Reactive Oxygen Species in both Hypoxic and Normoxic Conditions

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Overexpression of hypoxia-inducible factor and metabolic pathways: possible targets of cancer

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Hypoxia-Inducible Factor-1-Independent Regulation of Vascular Endothelial Growth Factor by Hypoxia in Colon Cancer

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Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses

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Targeted Anti–Vascular Endothelial Growth Factor Receptor-2 Therapy Leads to Short-term and Long-term Impairment of Vascular Function and Increase in Tumor Hypoxia

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Hypoxia Induces Transcription Factor ETS-1 via the Activity of Hypoxia-Inducible Factor-1

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Dynamics of Tumor Hypoxia Measured with Bioreductive Hypoxic Cell Markers

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Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor.

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Mechanisms of cisplatin resistance and targeting of cancer stem cells: Adding glycosylation to the equation

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Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro

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Cancer cells stemness: A doorstep to targeted therapy

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Caffeine Inhibits Adenosine-Induced Accumulation of Hypoxia-Inducible Factor-1α, Vascular Endothelial Growth Factor, and Interleukin-8 Expression in Hypoxic Human Colon Cancer Cells

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A Paclitaxel Prodrug Activatable by Irradiation in a Hypoxic Microenvironment

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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

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Impact of lactate on immune cell function in the tumor microenvironment: mechanisms and therapeutic perspectives

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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies

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Enhanced Photodynamic Cancer Treatment by Mitochondria‐Targeting and Brominated Near‐Infrared Fluorophores

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Mechanical Forces in Tumor Angiogenesis

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A Versatile Theranostic Nanoemulsion for Architecture‐Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy

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Hypoxia-inducible factor 1α is closely linked to an aggressive phenotype in breast cancer

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