Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

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Hypoxia-Mediated Metastasis

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Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner

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Hypoxia-Inducible Factor in Thyroid Carcinoma

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Hypoxia-inducible factor 2α (HIF-2α) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity

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Hypoxia‐Induced Acidification Causes Mitoxantrone Resistance Not Mediated by Drug Transporters in Human Breast Cancer Cells

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Dynamics of Hypoxia, Proliferation and Apoptosis after Irradiation in a Murine Tumor Model

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Temporal heterogeneity in oxygen tension in human melanoma xenografts

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Prognostic Value of Carbonic Anhydrase IX and Ki-67 Expression in Squamous Cell Carcinoma of the Tongue

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Antisense hypoxia‐inducible factor 1α gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma

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Generation of Oxygen Deficiency in Cell Culture Using a Two-Enzyme System to Evaluate Agents Targeting Hypoxic Tumor Cells

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Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

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Establishment and characterization of a new hypoxia-resistant cancer cell line, OCUM-12/Hypo, derived from a scirrhous gastric carcinoma

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Contemporary Perspectives on the Warburg Effect Inhibition in Cancer Therapy

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MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells

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Development of hypoxia-sensitive Gd3+-based MRI contrast agents

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Moderate Hypoxia Induces β-Cell Dysfunction with HIF-1–Independent Gene Expression Changes

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Pathophysiology of Solid Tumors

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The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis

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Meta-Alkoxy-Substituted Difluoroboron Dibenzoylmethane Complexes as Environment-Sensitive Materials

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Bioprinted Three-Dimensional Cell-Laden Hydrogels to Evaluate Adipocyte-Breast Cancer Cell Interactions

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Correlation of Tumor Oxygen Dynamics with Radiation Response of the Dunning Prostate R3327-HI Tumor1

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Genetic Analysis of Hypoxia Signaling and Response in C. elegans

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Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1α-independent manner

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HIF-1α and p53: the ODD couple?

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Orally administered pimonidazole to label hypoxic tumor cells.

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Photodynamic Therapy and Hyperthermia in Combination Treatment—Neglected Forces in the Fight against Cancer

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Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model – role of tumor stroma cells

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Novel Function of Orphan Nuclear Receptor Nur77 in Stabilizing Hypoxia-inducible Factor-1α

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Hypoxia-induced miR-210 in epithelial ovarian cancer enhances cancer cell viability via promoting proliferation and inhibiting apoptosis

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Metabolite profiling identifies a signature of tumorigenicity in hepatocellular carcinoma

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Photoacoustic Imaging in Oxygen Detection

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Tissue oxygen saturation predicts response to breast cancer neoadjuvant chemotherapy within 10 days of treatment

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Effects of Photodynamic Therapy with Redaporfin on Tumor Oxygenation and Blood Flow in a Lung Cancer Mouse Model

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Measurement of Hypoxia-related Parameters in Bronchial Mucosa by Use of Optical Spectroscopy

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Enhancing targeted radiotherapy by copper(II)diacetyl- bis(N4-methylthiosemicarbazone) using 2-deoxy-D-glucose.

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AMP-activated protein kinase activity is required for vanadate-induced hypoxia-inducible factor 1 expression in DU145 cells

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Radiation response non-invasively imaged by [18F]FDG-PET predicts local tumor control and survival in advanced oral squamous cell carcinoma

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Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma

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Hypoglycemic/hypoxic condition in vitro mimicking the tumor microenvironment markedly reduced the efficacy of anticancer drugs

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Selective Tumor Targeting by the Hypoxia-Activated Prodrug AQ4N Blocks Tumor Growth and Metastasis in Preclinical Models of Pancreatic Cancer

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Examining the relationship between Cu-ATSM hypoxia selectivity and fatty acid synthase expression in human prostate cancer cell lines

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Hypoxic Tumors and Their Effect on Immune Cells and Cancer Therapy

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Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells

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Progressive hypoxia‐on‐a‐chip: An in vitro oxygen gradient model for capturing the effects of hypoxia on primary hepatocytes in health and disease

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Oncolytic effects of adenovirus mutant capable of replicating in hypoxic and normoxic regions of solid tumor

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Design of Hypoxia-Targeting Drugs as New Cancer Chemotherapeutics

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A Phase 1 Open-Label, Accelerated Dose-Escalation Study of the Hypoxia-Activated Prodrug AQ4N in Patients with Advanced Malignancies

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Human Organ‐Specific 3D Cancer Models Produced by the Stromal Self‐Assembly Method of Tissue Engineering for the Study of Solid Tumors

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Ovarian Tumor Attachment, Invasion, and Vascularization Reflect Unique Microenvironments in the Peritoneum: Insights from Xenograft and Mathematical Models

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