Cited by 1,090Genetic and phenotypic traits in livestockRegulation of Appetite and ObesityGenetic Mapping and Diversity in Plants and Animals

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OBESE, A NEW MUTATION IN THE HOUSE MOUSE*

INGALLS, ANN M., DICKIE, MARGARET M., SNELL, G. D.·1950·Journal of Heredity

DOI 10.1093/oxfordjournals.jhered.a106073

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Leptin enhances porcine preimplantation embryo development in vitro
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“…has also beome evident (Holness et al., 1999; Gonzalez et al., 2000). bese mice exhibiting a congenital leptin deficiency (ob/ob) re sterile (Ingalls et al., 1950; Jones and Harrison, 1957). owever, this sterility can be reversed by exogenous lepin administration, but not by the restriction…”
Leptin-Deficient Mice Backcrossed to the BALB/cJ Genetic Background Have Reduced Adiposity, Enhanced Fertility, Normal Body Temperature, and Severe Diabetes
Qiu, J., Ogus, S., Mounzih, K., Toland, A. E., & Chehab, F. (2001) · Endocrinology · doi:10.1210/endo.142.8.8323 · Cited by 82
Relationship Between Periodontitis and Diabetes: Lessons From Rodent Studies
Pontes, C. D. N., Flyvbjerg, A., Buschard, K., & Holmstrup, P. (2007) · Journal of Periodontology · doi:10.1902/jop.2007.060491 · Cited by 81
Leptin and its potential interest in assisted reproduction cycles
Catteau, A., Caillon, H., Barrière, P., Denis, M. G., Masson, D., & Fréour, T. (2015) · Human Reproduction Update · doi:10.1093/humupd/dmv057 · Cited by 80
Leptin: Is It Thermogenic?
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Neuroanatomical Framework of the Metabolic Control of Reproduction
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“These autosomal recessive mutations were initially identified in mice at the Jackson Laboratories (named ob/ob or Lep for obese and db/db or Lepr for diabetes) (218, 222).”
Background
Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme
González-Casimiro, C. M., Merino, B., Casanueva-Álvarez, E., Postigo, T., Cámara-Torres, P., Fernández-Díaz, C. M., Leissring, M. A., Cózar‐Castellano, I., & Perdomo, G. (2021) · Biomedicines · doi:10.3390/biomedicines9010086 · Cited by 81

Authors: INGALLS, A. M., DICKIE, M. M., & SNELL, G. D.
Affiliations: Jackson Laboratory (US)
Venue: Journal of Heredity
Publisher: Oxford University Press (OUP)
Published: 1950-12
Volume: 41
Issue: 12
Pages: 317-318
ISSN: 0022-1503 (ISSN-L)
1465-7333
DOI: 10.1093/oxfordjournals.jhered.a106073
OpenAlex: W1896220440
Cited by: 1,090
References: 0
Citations by year: 2026: 14 · 2025: 27 · 2024: 22 · 2023: 22 · 2022: 31 · 2021: 44 · 2020: 28 · 2019: 35 · 2018: 23 · 2017: 42 · 2016: 33 · 2015: 38 · 2014: 56 · 2013: 52 · 2012: 50
FWCI: 9.18
Type: journal article
Language: en
Open access: closed
Locations: Journal of Heredity (publishedVersion)
PubMed (publishedVersion)
The Mouseion at the JAXlibrary (Jackson Laboratory) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and phenotypic traits in livestock
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Mapping and Diversity in Plants and Animals
Keywords: obesity, genetic mutations, house mouse, Mus musculus domesticus, genetic obesity, mutant phenotypes
MeSH terms: Animals, Genetics, Mutation, Mice

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