Cited by 339Psychedelics and Drug StudiesReligion, Spirituality, and PsychologyAlkaloids: synthesis and pharmacology

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil.

GROB, CHARLES S., McKENNA, DENNIS J., CALLAWAY, JAMES C., BRITO, GLACUS S., NEVES, EDISON S., OBERLAENDER, GUILHERME, SAIDE, OSWALDO L., LABIGALINI, ELIZEU, TACLA, CRISTIANE, MIRANDA, CLAUDIO T., STRASSMAN, RICK J., BOONE, KYLE B.·1996·The Journal of Nervous and Mental Disease

DOI 10.1097/00005053-199602000-00004

Open this paper in CoChat — free account

Abstract

A multinational, collaborative, biomedical investigation of the effects of hoasca (ayahuasca), a potent concoction of plant hallucinogens, was conducted in the Brazilian Amazon during the summer of 1993. This report describes the psychological assessment of 15 long-term members of a syncretic church that utilizes hoasca as a legal, psychoactive sacrament as well as 15 matched controls with no prior history of hoasca ingestion. Measures administered to both groups included structured psychiatric diagnostic interviews, personality testing, and neuropsychological evaluation. Phenomenological assessment of the altered state experience as well as semistructured and open-ended life story interviews were conducted with the long-term use hoasca group, but not the hoasca-naive control group. Salient findings included the remission of psychopathology following the initiation of hoasca use along with no evidence of personality or cognitive deterioration. Overall assessment revealed high functional status. Implications of this unusual phenomenon and need for further investigation are discussed.

Integrity signals

Registry

Crossref · 10.1097/00005053-199602000-00004

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A Systematic Method for Clinical Description and Classification of Personality Variants: A Proposal
Cloninger, C. R. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800180093014 · Cited by 3,678
L’examen Clinique en Psychologie
Rubé, P. (1959) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.1959.13.4.989 · Cited by 3,299
The Composite International Diagnostic Interview: An Epidemiologic Instrument Suitable for Use in Conjunction With Different Diagnostic Systems and in Different Cultures
Robins, L. N. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360017003 · Cited by 2,909
THE TRIDIMENSIONAL PERSONALITY QUESTIONNAIRE: U.S. NORMATIVE DATA
Cloninger, C. R., Przybeck, T. R., & Švrakić, D. M. (1991) · Psychological Reports · doi:10.2466/pr0.1991.69.3.1047 · Cited by 1,034
Cross-cultural Feasibility, Reliability and Sources of Variance of the Composite International Diagnostic Interview (CIDI)
Wittchen, H.-U., Robins, L. N., Cottler, L. B., Sartorius, N., Burke, J. D., Regier, D., & Trials, P. I. T. M. W. F. (1991) · British Journal of Psychiatry · doi:10.1192/bjp.159.5.645 · Cited by 833
Shamanism, Colonialism, and the Wild Man: A Study in Terror and Healing
Taussig, M. (2020) · Duke University Press eBooks · doi:10.1515/9780822390169-065 · Cited by 719
Plants of the Gods: Their Sacred, Healing and Hallucinogenic Powers
Hofmann, A., & Schultes, R. E. (1992) · Medical Entomology and Zoology · Cited by 469
Dose-response study of N,N-dimethyltryptamine in humans. II. Subjective effects and preliminary results of a new rating scale.
Strassman, R. J. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950020022002 · Cited by 453
Self-citation
Hallucinogens and shamanism
Harner, M. J. (1973) · Oxford University Press eBooks · Cited by 406
Monoamine oxidase inhibitors in South American hallucinogenic plants: Tryptamine and β-carboline constituents of ayahuasca
McKenna, D. J., Towers, G. H. N., & Abbott, F. (1984) · Journal of Ethnopharmacology · doi:10.1016/0378-8741(84)90003-5 · Cited by 398
Self-citation

Show all 23 references

Research works printed but not linked: 1

Dobkin de Rios, 1994, Yearbook of Ethnomedicine and the Study of Consciousness, 3, 113

Sorted by citations

Psychedelics
Nichols, D. E. (2016) · Pharmacological Reviews · doi:10.1124/pr.115.011478 · Cited by 1,762
Hallucinogens
Nichols, D. E. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2003.11.002 · Cited by 1,211
Human hallucinogen research: guidelines for safety
Johnson, M., Richards, W., & Griffiths, R. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108093587 · Cited by 1,203
Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness
MacLean, K. A., Johnson, M. W., & Griffiths, R. R. (2011) · Journal of Psychopharmacology · doi:10.1177/0269881111420188 · Cited by 895
Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial
Palhano-Fontes, F., Barreto, D., Onias, H., Andrade, K. C., Novaes, M. M., Pessoa, J. A., Mota-Rolim, S. A., Osório, F. L., Sanches, R., dos Santos, R. G., et al. (2019) · Psychological Medicine · doi:10.1017/s0033291718001356 · Cited by 852
“Over the last two decades, mental health evaluations of regular ayahuasca consumers have shown preserved cognitive function, increased well-being, reduction of anxiety, and depressive symptoms when compared to non-ayahuasca consumers (Grob et al., 1996; Bouso et al., 2012; Barbosa et al., 2016).”
BackgroundInfluential
Human pharmacology of ayahuasca: Subjective and cardiovascular effects, monoamine metabolite excretion, and pharmacokinetics
Riba, J., Valle, M., Urbano, G., Yritia, M., Morte, A., & Barbanoj, M. J. (2003) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.103.049882 · Cited by 390
Plants and the central nervous system
Carlini, E. A. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00112-6 · Cited by 357
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada
Thomas, G., Lucas, P., Capler, N., Tupper, K., & Martin, G. (2013) · Current Drug Abuse Reviews · doi:10.2174/15733998113099990003 · Cited by 330
Adverse effects of psychedelics: From anecdotes and misinformation to systematic science
Schlag, A. K., Aday, J. S., Salam, I., Neill, J. C., & Nutt, D. (2022) · Journal of Psychopharmacology · doi:10.1177/02698811211069100 · Cited by 359
Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges.
McKenna, D. J. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.03.002 · Cited by 321
Self-citation
Pharmacokinetics of Hoasca alkaloids in healthy humans
Callaway, J. C., McKenna, D. J., Grob, C. S., Brito, G. S., Raymon, L. P., Poland, R. E., Andrade, E. O., Andrade, E. O., & Mash, D. C. (1999) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(98)00168-8 · Cited by 318
Self-citation
Personality, psychopathology, life attitudes and neuropsychological performance among ritual users of ayahuasca: a longitudinal study.
Bouso, J. C., González, D., Fondevila, S., Cutchet, M., Fernández, X., Ribeiro Barbosa, P. C., Alcázar-Córcoles, M. Á., Araújo, W. S., Barbanoj, M. J., Fábregas, J. M., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042421 · Cited by 313
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years
dos Santos, R. G., Osório, F. L., Crippa, J. A. S., Riba, J., Zuardi, A. W., & Hallak, J. E. C. (2016) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125316638008 · Cited by 306
Subjective effects and tolerability of the South American psychoactive beverage ayahuasca in healthy volunteers
Riba, J., Rodríguez-Fornells, A., Urbano, G., Morte, A., Antonijoan, R., Montero, M., Callaway, J. C., & Barbanoj, M. J. (2001) · Psychopharmacology · doi:10.1007/s002130000606 · Cited by 303
Self-citation
Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates
Barrett, F. S., & Griffiths, R. R. (2017) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2017_474 · Cited by 273
Peak experiences and the afterglow phenomenon: When and how do therapeutic effects of hallucinogens depend on psychedelic experiences?
Majić, T., Schmidt, T. T., & Gallinat, J. (2015) · Journal of Psychopharmacology · doi:10.1177/0269881114568040 · Cited by 278
Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids.
Gable, R. S. (2007) · Addiction · doi:10.1111/j.1360-0443.2006.01652.x · Cited by 244
The therapeutic potentials of Ayahuasca: possible effects against various diseases of civilization
Frecska, E., Bokor, P., & Winkelman, M. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00035 · Cited by 242
Increased frontal and paralimbic activation following ayahuasca, the pan-amazonian inebriant
Riba, J., Romero, S., Grasa, E., Mena, E., Carrió, I., & Barbanoj, M. J. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0358-7 · Cited by 241
Psychedelics, personality and political perspectives.
Nour, M. M., Evans, L., & Carhart-Harris, R. L. (2017) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2017.1312643 · Cited by 226
Ayahuasca: pharmacology, neuroscience and therapeutic potential
Domínguez-Clavé, E., Soler, J., Elices, M., Pascual, J. C., Álvarez, E., de la Fuente Revenga, M., Friedlander, P., Feilding, A., & Riba, J. (2016) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2016.03.002 · Cited by 226
Assessment of addiction severity among ritual users of ayahuasca.
Fábregas, J. M., González, D., Fondevila, S., Cutchet, M., Fernández, X., Barbosa, P. C. R., Alcázar-Córcoles, M. Á., Barbanoj, M. J., Riba, J., & Bouso, J. C. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.03.024 · Cited by 227
Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans.
Bouso, J. C., Palhano-Fontes, F., Rodríguez-Fornells, A., Ribeiro, S., Sanches, R., Crippa, J. A. S., Hallak, J. E. C., de Araujo, D. B., & Riba, J. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.01.008 · Cited by 218
Hallucinogens and dissociative agents naturally growing in the United States
Halpern, J. H. (2004) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.03.003 · Cited by 222
Secondary Metabolites from Rubiaceae Species
Martins, D., & Núñez, C. V. (2015) · Molecules · doi:10.3390/molecules200713422 · Cited by 212
Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution.
Uthaug, M. V., van Oorsouw, K., Kuypers, K. P. C., van Boxtel, M., Broers, N. J., Mason, N. L., Toennes, S. W., Riba, J., & Ramaekers, J. G. (2018) · Psychopharmacology · doi:10.1007/s00213-018-4988-3 · Cited by 212
The globalization of ayahuasca: harm reduction or benefit maximization?
Tupper, K. W. (2008) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2006.11.001 · Cited by 212
Binding of β-carbolines and related agents at serotonin (5-HT2 and 5-HT1A), dopamine (D2) and benzodiazepine receptors
Glennon, R. A., Dukat, M., Grella, B. S., Hong, S., Costantino, L., Teitler, M., Smith, C., Egan, C., Davis, K., & Mattson, M. V. (2000) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(99)00148-9 · Cited by 210
Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members
SANTOS, R. G. D., Landeira-Fernández, J., Strassman, R. J., Motta, V., & Cruz, A. P. D. M. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.04.012 · Cited by 212
Self-citation
Clinical applications of hallucinogens: a review
Garcia-Romeu, A., Kersgaard, B., & Addy, P. H. (2016) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000084 · Cited by 201
Psychedelic medicine: a re-emerging therapeutic paradigm
Tupper, K. W., Wood, E., Yensen, R., & Johnson, M. W. (2015) · Canadian Medical Association Journal · doi:10.1503/cmaj.141124 · Cited by 187
Increased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression
Lyons, T., & Carhart-Harris, R. L. (2018) · Journal of Psychopharmacology · doi:10.1177/0269881117748902 · Cited by 201
Ayahuasca: Psychological and Physiologic Effects, Pharmacology and Potential Uses in Addiction and Mental Illness
Hamill, J., Hallak, J. E. C., Dursun, S. M., & Baker, G. B. (2018) · Current Neuropharmacology · doi:10.2174/1570159x16666180125095902 · Cited by 201
Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies
SANTOS, R. G. D., Osório, F. D. L., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2015-1701 · Cited by 175
Therapeutic Effects of Ritual Ayahuasca Use in the Treatment of Substance Dependence—Qualitative Results
Loizaga-Velder, A. K., & Verres, R. (2014) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2013.873157 · Cited by 157
Plant-Based Medicines for Anxiety Disorders, Part 2: A Review of Clinical Studies with Supporting Preclinical Evidence
Sarris, J. J., McIntyre, E., & Camfield, D. (2013) · CNS Drugs · doi:10.1007/s40263-013-0059-9 · Cited by 157
Hallucinogenic Drugs and Plants in Psychotherapy and Shamanism
Metzner, R. (1998) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1998.10399709 · Cited by 142
Developments in harmine pharmacology — Implications for ayahuasca use and drug-dependence treatment
Brierley, D. I., & Davidson, C. (2012) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.06.001 · Cited by 138
Ayahuasca Preparations and Serotonin Reuptake Inhibitors: A Potential Combination for Severe Adverse Interactions
Callaway, J. C., & Grob, C. S. (1998) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1998.10399712 · Cited by 137
Self-citation
Autonomic, Neuroendocrine, and Immunological Effects of Ayahuasca
SANTOS, R. G. D., Valle, M., Bouso, J. C., Nomdedeu, J. F., Rodrı́guez-Espinosa, J., McIlhenny, E. H., Barker, S. A., Barbanoj, M. J., & Riba, J. (2011) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0b013e31823607f6 · Cited by 143
Serotonergic psychedelics and personality: A systematic review of contemporary research
Bouso, J. C., dos Santos, R. G., Alcázar-Córcoles, M. Á., & Hallak, J. E. C. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.02.004 · Cited by 134
Psychedelics as Medicines for Substance Abuse Rehabilitation: Evaluating Treatments with LSD, Peyote, Ibogaine and Ayahuasca
Winkelman, M. (2015) · Current Drug Abuse Reviews · doi:10.2174/1874473708666150107120011 · Cited by 126
The current state of research on ayahuasca: a systematic review of human studies assessing psychiatric symptoms, neuropsychological functioning, and neuroimaging
dos Santos, R. G., Balthazar, F. M., Bouso, J. C., & Hallak, J. E. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116652578 · Cited by 125
Report on psychoactive drug use among adolescents using ayahuasca within a religious context.
Doering-Silveira, E., Grob, C. S., de Rios, M. D., Lopez, E., Alonso, L. K., Tacla, C., & Da Silveira, D. X. (2005) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2005.10399794 · Cited by 122
Self-citation
Classical hallucinogens as antidepressants? A review of pharmacodynamics and putative clinical roles
Baumeister, D., Barnes, G. L., Giaroli, G., & Tracy, D. K. (2014) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125314527985 · Cited by 127
‘Altered States of Consciousness and Short-Term Psychological After-Effects Induced by the First Time Ritual Use of Ayahuasca in an Urban Context in Brazil’
Barbosa, P. C. R., Giglio, J. S., & Dalgalarrondo, P. (2005) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2005.10399801 · Cited by 120
Traditional Medicine in the Treatment of Drug Addiction
Lu, L., Liu, Y.-L., Zhu, W.-L., Shi, J., Liu, Y., Ling, W., & Kosten, T. (2009) · The American Journal of Drug and Alcohol Abuse · doi:10.1080/00952990802455469 · Cited by 116
Toxicokinetics and Toxicodynamics of Ayahuasca alkaloids N,N-dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: clinical and forensic impact
Brito-da-Costa, A. M., Dias-da-Silva, D., Gomes, N. G. M., Dinis-Oliveira, R. J., & Madureira-Carvalho, Á. (2020) · Pharmaceuticals · doi:10.3390/ph13110334 · Cited by 117
Dark Classics in Chemical Neuroscience:N,N-Dimethyltryptamine (DMT)
Cameron, L. P., & Olson, D. E. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00101 · Cited by 128
Treatment of alcoholism using psychedelic drugs: a review of the program of research.
Mangini, M. (1998) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1998.10399714 · Cited by 114
Therapeutic use of serotoninergic hallucinogens: A review of the evidence and of the biological and psychological mechanisms
dos Santos, R. G., & Hallak, J. E. C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.12.001 · Cited by 111
Acute biphasic effects of ayahuasca.
Schenberg, E. E., Alexandre, J. F. M., Filev, R., Cravo, A. M., Sato, J. R., Muthukumaraswamy, S. D., Yonamine, M., Waguespack, M., Lomnicka, I., Barker, S. A., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137202 · Cited by 111
Ayahuasca in Adolescence: A Preliminary Psychiatric Assessment
Da Silveira, D. X., Grob, C. S., de Rios, M. D., Lopez, E., Alonso, L. K., Tacla, C., & Doering-Silveira, E. (2005) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2005.10399792 · Cited by 113
Self-citation
A placebo-controlled study of the effects of ayahuasca, set and setting on mental health of participants in ayahuasca group retreats
Uthaug, M. V., Mason, N. L., Toennes, S. W., Reckweg, J. T., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., van Oorsouw, K., Riba, J., & Ramaekers, J. G. (2021) · Psychopharmacology · doi:10.1007/s00213-021-05817-8 · Cited by 112
Health status of ayahuasca users
Barbosa, P. C. R., Mizumoto, S., Bogenschutz, M. P., & Strassman, R. J. (2012) · Drug Testing and Analysis · doi:10.1002/dta.1383 · Cited by 112
Self-citation
Effects of ayahuasca on mental health and quality of life in naïve users: a longitudinal and cross-sectional study combination.
Jiménez-Garrido, D. F., Gómez-Sousa, M., Ona, G., Dos Santos, R. G., Hallak, J. E. C., Alcázar-Córcoles, M. Á., & Bouso, J. C. (2020) · Scientific Reports · doi:10.1038/s41598-020-61169-x · Cited by 110
A Six-Month Prospective Evaluation of Personality Traits, Psychiatric Symptoms and Quality of Life in Ayahuasca-Naïve Subjects
Barbosa, P. C. R., Cazorla, I. M., Giglio, J. S., & Strassman, R. J. (2009) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2009.10400530 · Cited by 108
Self-citation
Ayahuasca Tourism: Participants in Shamanic Rituals and their Personality Styles, Motivation, Benefits and Risks
Kavenská, V., & Simonová, H. (2015) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2015.1094590 · Cited by 108
Psychological and neuropsychological assessment of regular hoasca users
Barbosa, P. C. R., Strassman, R. J., da Silveira, D. X., Areco, K., Hoy, R., Pommy, J., Thoma, R., & Bogenschutz, M. (2016) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2016.09.003 · Cited by 105
Self-citation
Exploring ayahuasca‐assisted therapy for addiction: A qualitative analysis of preliminary findings among an Indigenous community in Canada
Argento, E., Capler, R., Thomas, G., Lucas, P., & Tupper, K. W. (2019) · Drug and Alcohol Review · doi:10.1111/dar.12985 · Cited by 102
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial
Rothberg, R. L., Azhari, N., Haug, N. A., & Dakwar, E. (2021) · Journal of Psychopharmacology · doi:10.1177/0269881120970879 · Cited by 97
Experiences of encounters with Ayahuasca–“the vine of the soul”
Kjellgren, A., Eriksson, A., & Norlander, T. (2009) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2009.10399767 · Cited by 97
Assessment of Alcohol and Tobacco Use Disorders Among Religious Users of Ayahuasca
Barbosa, P. C. R., Tófoli, L. F., Bogenschutz, M. P., Hoy, R. V., Berro, L. F., Marinho, E. A. V., Areco, K. C. N., & Winkelman, M. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00136 · Cited by 97
Effects of Ayahuasca and its Alkaloids on Drug Dependence: A Systematic Literature Review of Quantitative Studies in Animals and Humans
Nunes, A. A., SANTOS, R. G. D., Osório, F. D. L., Sanches, R. F., Crippa, J. A. S., & Hallak, J. E. C. (2016) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2016.1188225 · Cited by 95
Effects of ayahuasca on the development of ethanol-induced behavioral sensitization and on a post-sensitization treatment in mice.
Oliveira-Lima, A. J., Santos, R., Hollais, A. W., Gerardi-Junior, C. A., Baldaia, M. A., Wuo-Silva, R., Yokoyama, T. S., Costa, J. L., Malpezzi-Marinho, E. L. A., Ribeiro-Barbosa, P. C., et al. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.01.032 · Cited by 91
Investigation of hallucinogenic and related β-carbolines
Grella, B. S., Dukat, M., Young, R., Teitler, M., Herrick‐Davis, K., Gauthier, C. B., & Glennon, R. A. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(97)00163-4 · Cited by 89
Assessing the risk–benefit profile of classical psychedelics: a clinical review of second-wave psychedelic research
Bender, D., & Hellerstein, D. J. (2022) · Psychopharmacology · doi:10.1007/s00213-021-06049-6 · Cited by 88
Safety and Side Effects of Ayahuasca in Humans—An Overview Focusing on Developmental Toxicology
SANTOS, R. G. D. (2013) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2013.763564 · Cited by 94
Examining changes in personality following shamanic ceremonial use of ayahuasca
Weiss, B., Miller, J. D., Carter, N. T., & Keith Campbell, W. (2021) · Scientific Reports · doi:10.1038/s41598-021-84746-0 · Cited by 86
Avanços nas pesquisas etnobotânicas no Brasil
de Oliveira, F. C., Albuquerque, U. P., da Fonseca-Kruel, V. S., & Hanazaki, N. (2009) · Acta Botanica Brasilica · doi:10.1590/s0102-33062009000200031 · Cited by 86
Lasting effects of a single psilocybin dose on resting-state functional connectivity in healthy individuals
McCulloch, D. E.-W., Madsen, M. K., Stenbæk, D. S., Kristiansen, S., Ozenne, B., Jensen, P. S., Knudsen, G. M., & Fisher, P. M. (2021) · Journal of Psychopharmacology · doi:10.1177/02698811211026454 · Cited by 83
Ayahuasca improves emotion dysregulation in a community sample and in individuals with borderline-like traits
Domínguez‐Clavé, E., Soler, J., Pascual, J. C., Elices, M., Franquesa, A., Valle, M., Álvarez, E., & Riba, J. (2018) · Psychopharmacology · doi:10.1007/s00213-018-5085-3 · Cited by 86
Do hallucinogens cause residual neuropsychological toxicity?
Halpern, J. H., & Pope, H. G. (1999) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00129-x · Cited by 82
More Realistic Forecasting of Future Life Events After Psilocybin for Treatment-Resistant Depression
Lyons, T., & Carhart-Harris, R. L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01721 · Cited by 77
Ayahuasca and public health: health status, psychosocial well-being, lifestyle, and coping strategies in a large sample of ritual ayahuasca users
Ona, G., Kohek, M., Massaguer, T., Gomariz, A., Jiménez, D. F., Dos Santos, R. G., Hallak, J. E. C., Alcázar-Córcoles, M. Á., & Bouso, J. C. (2019) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2019.1567961 · Cited by 76
Entheogens and Existential Intelligence: The Use of Plant Teachers as Cognitive Tools
Tupper, K. W. (2002) · Canadian Journal of Education / Revue canadienne de l éducation · doi:10.2307/1602247 · Cited by 78
Therapeutic effect of an ayahuasca analogue in clinically depressed patients: a longitudinal observational study
van Oorsouw, K., Toennes, S. W., & Ramaekers, J. G. (2022) · Psychopharmacology · doi:10.1007/s00213-021-06046-9 · Cited by 74
Ayahuasca in Adolescence: A Neuropsychological Assessment
Doering-Silveira, E., López, E., Grob, C. S., de Ríos, M. D., Alonso, L. K., Tacla, C., Shirakawa, I., Bertolucci, P. H. F., & da Silveira, D. X. (2005) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2005.10399791 · Cited by 72
Self-citation
Dimethyltryptamine (DMT): Subjective effects and patterns of use among Australian recreational users
Cakic, V., Potkonyak, J., & Marshall, A. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.03.015 · Cited by 72
Changes in Spirituality Among Ayahuasca Ceremony Novice Participants
Trichter, S., Klimo, J., & Krippner, S. (2009) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2009.10399905 · Cited by 79
Psychometric assessment of the Hallucinogen Rating Scale☆
Riba, J., Rodrı́guez-Fornells, A., Strassman, R. J., & Barbanoj, M. J. (2001) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(00)00175-7 · Cited by 88
Self-citation
Hallucinogen use and intimate partner violence: Prospective evidence consistent with protective effects among men with histories of problematic substance use
Walsh, Z., Hendricks, P. S., Smith, S. D., Kosson, D. S., Thiessen, M. S., Lucas, P., & Swogger, M. T. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116642538 · Cited by 67
Effects of the Naturalβ-Carboline Alkaloid Harmine, a Main Constituent of Ayahuasca, in Memory and in the Hippocampus: A Systematic Literature Review of Preclinical Studies
SANTOS, R. G. D., & Hallak, J. E. C. (2016) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2016.1260189 · Cited by 66
Psychoactive Plants and Ethnopsychiatric Medicines of the Matsigenka
Shepard, G. H. (1998) · Journal of Psychoactive Drugs · doi:10.1080/02791072.1998.10399708 · Cited by 61
A review of transpersonal theory and its application to the practice of psychotherapy.
Kasprow, M. C., & Scotton, B. W. (1999) · PubMed Central · Cited by 60
Hallucinogens and Redemption
de Ríos, M. D., Grob, C. S., & Baker, J. R. (2002) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2002.10399960 · Cited by 61
Self-citation
Psychological variables implied in the therapeutic effect of ayahuasca: A contextual approach
Franquesa, A., Sainz-Cort, A., Gandy, S., Soler, J., Alcázar-Córcoles, M. Á., & Bouso, J. C. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.04.012 · Cited by 58
Classic and non‐classic psychedelics for substance use disorder: A review of their historic, past and current research
Mendes, F. R., Costa, C. D. S., Wiltenburg, V. D., Morales-Lima, G., Fernandes, J. A. B., & Filev, R. (2022) · Addiction Neuroscience · doi:10.1016/j.addicn.2022.100025 · Cited by 67
Modulatory effects of ayahuasca on personality structure in a traditional framework
Netzband, N., Ruffell, S., Linton, S., Tsang, W., & Wolff, T. J. (2020) · Psychopharmacology · doi:10.1007/s00213-020-05601-0 · Cited by 56
Ayahuasca: Uses, Phytochemical and Biological Activities
Estrella-Parra, E. A., Almanza-Pérez, J. C., & Alarcón-Aguilar, F. J. (2019) · Natural Products and Bioprospecting · doi:10.1007/s13659-019-0210-5 · Cited by 61
Associations between ayahuasca consumption in naturalistic settings and current alcohol and drug use: Results of a large international cross‐sectional survey
Perkins, D., Opaleye, E. S., Šimonová, H., Bouso, J. C., Tófoli, L. F., Coelho, N. L. G., Schubert, V., & Sarris, J. J. (2021) · Drug and Alcohol Review · doi:10.1111/dar.13348 · Cited by 54
Serotonergic Hallucinogens and Emerging Targets for Addiction Pharmacotherapies
Ross, S. (2012) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2012.04.002 · Cited by 54
Policy considerations that support equitable access to responsible, accountable, safe, and ethical uses of psychedelic medicines
Belouin, S. J., Averill, L. A., Henningfield, J. E., Xenakis, S. N., Donato, I., Grob, C. S., Berger, A., Magar, V., Danforth, A. L., & Anderson, B. T. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109214 · Cited by 54
Self-citation
Ritualistic Use of Ayahuasca versus Street Use of Similar Substances Seized by the Police: A Key Factor Involved in the Potential for Intoxications and Overdose?
Lanaro, R., Calemi, D. B. D. A., Togni, L. R., Costa, J. L., Yonamine, M., Cazenave, S. O. S., & Linardi, A. (2015) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2015.1013202 · Cited by 52
Changes in aminoacidergic and monoaminergic neurotransmission in the hippocampus and amygdala of rats after ayahuasca ingestion
de Castro-Neto, E. F., da Cunha, R. H., da Silveira, D. X., Yonamine, M., Gouveia, T. L. F., Cavalheiro, É. A., Amado, D., & Naffah‐Mazzacoratti, M. D. G. (2013) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v4.i4.141 · Cited by 52
Behavioral profile of constituents in ayahuasca, an Amazonian psychoactive plant mixture
Freedland, C. S., & Mansbach, R. S. (1999) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00154-9 · Cited by 51
Ayahuasca and Its DMT- and β-carbolines – Containing Ingredients Block the Expression of Ethanol-Induced Conditioned Place Preference in Mice: Role of the Treatment Environment
Cata-Preta, E. G., Serra, Y. A., Moreira-Junior, E. D. C., Reis, H. S., Kisaki, N. D., Libarino-Santos, M., Silva, R. R. R., Barros-Santos, T., Santos, L. C., Barbosa, P. C. R., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00561 · Cited by 53
Risk assessment of ayahuasca use in a religious context: self-reported risk factors and adverse effects
Durante, Í., SANTOS, R. G. D., Bouso, J. C., & Hallak, J. E. C. (2020) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2020-0913 · Cited by 59
Ayahuasca: A review of historical, pharmacological, and therapeutic aspects
Ruffell, S., Crosland‐Wood, M., Palmer, R., Netzband, N., Tsang, W., Weiss, B., Gandy, S., Cowley‐Court, T., Halman, A., McHerron, D., et al. (2023) · Psychiatry and Clinical Neurosciences Reports · doi:10.1002/pcn5.146 · Cited by 61
Effects of Ayahuasca on the Recognition of Facial Expressions of Emotions in Naive Healthy Volunteers
Rocha, J. M., Rossi, G. N., Osório, F. D. L., Bouso, J. C., Silveira, G. D. O., Yonamine, M., Campos, A. C., Bertozi, G., Hallak, J. E. C., & SANTOS, R. G. D. (2021) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001396 · Cited by 50

Authors: GROB, C. S., McKENNA, D. J., CALLAWAY, J. C., BRITO, G. S., NEVES, E. S., OBERLAENDER, G., SAIDE, O. L., LABIGALINI, E., TACLA, C., MIRANDA, C. T., STRASSMAN, R. J., & BOONE, K. B.
Affiliations: University of California, Los Angeles (US)
University of Eastern Finland (FI)
University of New Mexico (US)
ORCID: BOONE, KYLE B.
Venue: The Journal of Nervous and Mental Disease
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1996-02
Volume: 184
Issue: 2
Pages: 86-94
ISSN: 0022-3018 (ISSN-L)
DOI: 10.1097/00005053-199602000-00004
OpenAlex: W2161617741
Cited by: 338
References: 23
Citations by year: 2026: 12 · 2025: 15 · 2024: 19 · 2023: 21 · 2022: 25 · 2021: 26 · 2020: 14 · 2019: 14 · 2018: 22 · 2017: 10 · 2016: 20 · 2015: 16 · 2014: 8 · 2013: 17 · 2012: 14
FWCI: 7.37
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Nervous and Mental Disease (publishedVersion)
PubMed (publishedVersion)
UNIFESP Institutional Repository (Universidade Federal de São Paulo) (submittedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Psychedelics and Drug Studies
Social Sciences › Health › Religion, Spirituality, and Psychology
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Alkaloids: synthesis and pharmacology
Keywords: ayahuasca, ritual drug use, personality, cognitive function, altered states of consciousness, life story interviews, Amazonian indigenous peoples
MeSH terms: Adult, Mental Disorders, Brazil, Cognition, Hallucinogens, Harmine, Humans, Magic, Male, Medicine, Traditional, Middle Aged, Neuropsychological Tests, Personality, Plants, Medicinal, Psychiatric Status Rating Scales, Religion and Medicine, Tea, Verbal Learning, Substance-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Human psychopharmacology of hoasca, a plant hallucinogen used in ritual context in Brazil.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks