Cited by 175Probiotics and Fermented FoodsFatty Acid Research and HealthGut microbiota and health

Antiobesity effect of trans-10,cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice

Lee, K., Paek, K., Lee, H.Y., Park, J.H., Lee, Y.·2007·Journal of Applied Microbiology

Abstract

AIMS: To observe the antiobesity activity of trans-10,cis-12-conjugated linoleic acid (CLA)-producing lactobacillus in mice. METHODS AND RESULTS: Lactobacillus plantarum PL62, which can grow in the presence of linoleic acid, was selected and studied. The culture supernatant of Lact. plantarum PL62 contained trans-10,cis-12-conjugated linoleic acid (6.4 microg ml(-1)), and the crude enzyme prepared from washed cells produced trans-10,cis-12 CLA (1395 microg mg(-1) protein). Lact. plantarum PL62 reduced the weights of epididymal, inguinal, mesenteric, and perirenal white adipose tissues and significantly reduced the blood levels of total glucose and body weights of mice (P<0.01). CONCLUSIONS: trans-10,cis-12-CLA-producing Lact. plantarum PL62 can exert the same antiobesity activity as trans-10,cis-12-CLA in mice. SIGNIFICANCE AND IMPACT OF THE STUDY: trans-10,cis-12-CLA-producing Lactobacillus can be a replacement for CLA for obesity treatment via the continuous production of trans-10,cis-12-CLA. The results provide a novel opportunity to develop foods with antiobesity activity.

Integrity signals

Registry

Crossref · 10.1111/j.1365-2672.2007.03336.x

Cites

28 of 28 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Lee, K., Paek, K., Lee, H. Y., Park, J. H., & Lee, Y.
Affiliations
  • Seoul Women's University (KR)
  • Soongsil University (KR)
  • Seoul National University (KR)
Corresponding author
Lee, K.
Venue
Journal of Applied Microbiology
Published
2007-10
Volume
103
Issue
4
Pages
1140-1146
ISSN
  • 1364-5072 (ISSN-L)
  • 1365-2672
OpenAlex
W2155921937
Cited by
175
References
28
Citations by year
2025: 5 · 2024: 5 · 2023: 5 · 2022: 10 · 2021: 6 · 2020: 10 · 2019: 6 · 2018: 5 · 2017: 14 · 2016: 18 · 2015: 16 · 2014: 16 · 2013: 19 · 2012: 10
FWCI
10.31
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Applied Microbiology (publishedVersion)
  • PubMed (publishedVersion)
  • Seoul National University Open Repository (Seoul National University) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
trans-10, cis-12 conjugated linoleic acid, anti-obesity, diet-induced obesity, white adipose tissue, linoleic acid, probiotics, obesity treatment, functional foods
MeSH terms
Animals, Energy Intake, Chromatography, Gas, Dietary Fats, Eating, Feces, Glycerol, Lipids, Male, Mice, Inbred C57BL, Obesity, Organ Size, Weight Gain, Probiotics, Leptin, Linoleic Acids, Conjugated, Lactobacillus plantarum, Lactiplantibacillus plantarum, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review