ARGINASE: A CRITICAL REGULATOR OF NITRIC OXIDE SYNTHESIS AND VASCULAR FUNCTION

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POLYAMINES

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Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

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Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

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Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

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Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox

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Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation

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Arginase modulates nitric oxide production in activated macrophages

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α‐Lipoic acid inhibits TNF‐a‐induced NF‐κB activation and adhesion molecule expression in human aortic endothelial cells

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Arginine Nutrition and Cardiovascular Function

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Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production

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Thrombin Stimulates Human Endothelial Arginase Enzymatic Activity via RhoA/ROCK Pathway

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Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide‐mediated vasodilatory function

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Human type II arginase: sequence analysis and tissue-specific expression

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Increased Expression of Arginase II in Human Diabetic Corpus Cavernosum: In Diabetic-Associated Erectile Dysfunction

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Upregulation of Vascular Arginase in Hypertension Decreases Nitric Oxide–Mediated Dilation of Coronary Arterioles

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Cloning and Characterization of the Human Type II Arginase Gene

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Carbon monoxide inhibits apoptosis in vascular smooth muscle cells

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Ischemia‐reperfusion selectively impairs nitric oxide‐ mediated dilation in coronary arterioles: counteracting role of arginase

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Translational Control of Inducible Nitric Oxide Synthase by IL-13 and Arginine Availability in Inflammatory Macrophages

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Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats

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Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness

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Nω-Hydroxy-L-Arginine, an Intermediate in the L-Arginine to Nitric Oxide Pathway, Is a Strong Inhibitor of Liver and Macrophage Arginase

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Mouse Model for Human Arginase Deficiency

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Arginase: Structure, Mechanism, and Physiological Role in Male and Female Sexual Arousal

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Arginase 1 Overexpression in Psoriasis

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IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells

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Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation

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Arginase inhibition increases nitric oxide production in bovine pulmonary arterial endothelial cells

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Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats

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Transforming Growth Factor-β 1 Stimulates l -Arginine Transport and Metabolism in Vascular Smooth Muscle Cells

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Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation

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Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension

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Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene

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Effects of the New Arginase Inhibitor Nω-Hydroxy-nor-l-Arginine on NO Synthase Activity in Murine Macrophages

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Hyperargininemia due to liver arginase deficiency

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Increased Arginase Activity in Cystic Fibrosis Airways

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Inhibition of arginase in rat and rabbit alveolar macrophages by Nω‐hydroxy‐ D , L ‐indospicine, effects on L ‐arginine utilization by nitric oxide synthase

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Arginase pathway in human endothelial cells in pathophysiological conditions

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L-arginine improves endothelium-dependent vasorelaxation and reduces intimal hyperplasia after balloon angioplasty.

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Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase.

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Physiological cyclic stretch directs L‐arginine transport and metabolism to collagen synthesis in vascular smooth muscle

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Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia

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L-Arginine in cardiovascular disease: dream or reality?

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Isolation of human liver arginase cdna and demonstration of nonhomology between the two human arginase genes

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Growth Hormone Overexpression in the Central Nervous System Results in Hyperphagia-Induced Obesity Associated With Insulin Resistance and Dyslipidemia

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Asymmetric Dimethylarginine, Derangements of the Endothelial Nitric Oxide Synthase Pathway, and Cardiovascular Diseases

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Platelet-derived Growth Factor Regulates Vascular Smooth Muscle Cell Proliferation by Inducing Cationic Amino Acid Transporter Gene Expression

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Expression and Activity of Arginase Isoenzymes During Normal and Diabetes-Impaired Skin Repair

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Three Different Oxygen-induced Radical Species in Endothelial Nitric-oxide Synthase Oxygenase Domain under Regulation by L-Arginine and Tetrahydrobiopterin

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Urea inhibits inducible nitric oxide synthase in macrophage cell line

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Identification of Macrophage Arginase I as a New Candidate Gene of Atherosclerosis Resistance

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Cytokine-Induced Endothelial Arginase Expression Is Dependent on Epidermal Growth Factor Receptor

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Agents that modify EDRF formation alter antiplatelet properties of brain arteriolar endothelium in vivo

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INCREASED ARGINASE ACTIVITY IN AORTA OF MINERALOCORTICOID-SALT HYPERTENSIVE RATS

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Lysophosphatidylcholine Regulates Cationic Amino Acid Transport and Metabolism in Vascular Smooth Muscle Cells

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Cytokine treatment increases arginine metabolism and uptake in bovine pulmonary arterial endothelial cells

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Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide.

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Regulation of L-Arginine Transport and Metabolism in Vascular Smooth Muscle Cells

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Thrombin Stimulates Vascular Smooth Muscle Cell Polyamine Synthesis by Inducing Cationic Amino Acid Transporter and Ornithine Decarboxylase Gene Expression

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Modulation of contractility by myocyte-derived arginase in normal and hypertrophied feline myocardium

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Accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, attenuated dimethylarginine dimethylaminohydrolase activity and intimal hyperplasia in premenopausal human uterine arteries

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An experiment of nature: genetic l-arginine deficiency and NO insufficiency

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Intimal hyperplasia is reduced by ornithine decarboxylase inhibition

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Arginase in Glomerulonephritis

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ARGINASE PROMOTES VASCULAR SMOOTH MUSCLE CELL PROLIFERATION AND NEOINTIMA FORMATION

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Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

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Arginine metabolism and nutrition in growth, health and disease

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Endothelial Dysfunction and Diabetes: Effects on Angiogenesis, Vascular Remodeling, and Wound Healing

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Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasisPreprint

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Amino acid metabolism in health and disease

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Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

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Arginase: A Multifaceted Enzyme Important in Health and Disease

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Recent advances in arginine metabolism: roles and regulation of the arginases

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Cellular backpacks for macrophage immunotherapy

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Cutaneous Vasodilator and Vasoconstrictor Mechanisms in Temperature Regulation

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Thirty Years of Saying NO

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Regulation of nitric oxide production in health and disease

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Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?

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Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis

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Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats

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Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

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